Title: Mesopotamia Guest Houses from CA $211 | Expedia.ca [Hotels in Mesopotamia](https://expedia.ca/Mesopotamia-Hotels.d3000453277.Travel-Guide-Hotels)[Vacation Rentals in Mesopotamia](https://expedia.ca/Mesopotamia-Vacation-Rentals.d3000453277.Travel-Guide-VacationRentals)[Flights to Mesopotamia](https://expedia.ca/Cheap-Flights-To-Mesopotamia.d3000453277.Travel-Guide-Flights)[Mesopotamia Car Rentals](https://expedia.ca/Car-Rentals-In-Mesopotamia.d3000453277.Car-Rental-Guide)[Mesopotamia Vacation Packages](https://expedia.ca/Mesopotamia.d3000453277.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Next weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-03-13&endDate=2026-03-15&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-03-20&endDate=2026-03-22&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-04-03&endDate=2026-04-05&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=3000453277&startDate=2026-05-01&endDate=2026-05-03&adults=2&lodging=GUEST_HOUSE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mesopotamia guest houses ![Interior](https://images.trvl-media.com/lodging/42000000/41020000/41013100/41013100/3997b79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/42000000/41020000/41013100/41013100/891c9bd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/42000000/41020000/41013100/41013100/b5104632.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/42000000/41020000/41013100/41013100/844b9480.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bonnie's Guesthouse @ Peridot Equine Sanctuary [](https://www.expedia.ca/Cleveland-Hotels-Bonnies-Guesthouse-Peridot-Equine-Sanctuary.h41013100.Hotel-Information) Chardon 9.6/10 Exceptional (79 reviews) "Beautiful property, well decorated, comfortable. We enjoyed our visit" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffrey M. CA $205 CA $232 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Cleveland-Hotels-Bonnies-Guesthouse-Peridot-Equine-Sanctuary.h41013100.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/101000000/100940000/100932300/100932202/7894b591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100940000/100932300/100932202/50a894de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/101000000/100940000/100932300/100932202/dbf98efb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100940000/100932300/100932202/f7f15733.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy two bedroom house close to Middlefield, and not far from Route 80 and 422 [](https://www.expedia.ca/West-Farmington-Hotels-Cozy-Two-Bedroom-House-Close-To-Middlefield.h100932202.Hotel-Information) West Farmington 10/10 Exceptional (14 reviews) "Everything in this stay was great. My family and I enjoyed our stay & felt welcomed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ana V. CA $157 CA $211 total includes taxes & fees Mar 28 - Mar 29 [](https://www.expedia.ca/West-Farmington-Hotels-Cozy-Two-Bedroom-House-Close-To-Middlefield.h100932202.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-17&endDate=2026-03-18®ionId=3000453277&adults=2&lodging=GUEST_HOUSE&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=AA_SPRING_PROMO_3000453277) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Guest-Houses.d3000453277-aaGuestHouses.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMesopotamia-Guest-Houses.d3000453277-aaGuestHouses.Travel-Guide-Accommodation) ## Top Mesopotamia Hotel Reviews ![Log Home, Pvt Pond-Swim, Hot Tub](https://images.trvl-media.com/lodging/114000000/113220000/113215000/113214960/9161e6ee_y.jpg) ### Log Home, Pvt Pond-Swim, Hot Tub 10/10 Excellent "We have rented a lot of places for our large group of friends but I can say, without a doubt, that this was our favorite place by far. Can’t say enough about how pristinely clean, well stocked and fun Winding Wood cabin was. We’ve already rented it again for next year. From the large kitchen/dining room area, the coffee bar/room, the game room, the theater room and the bedrooms with extremely comfortable mattresses, you can’t go wrong staying here. There’s even a large hot tub that was used during the dead of winter. Had a couple of questions for the owners which were promptly addressed. You won’t be disappointed if you decide to stay here. We sure weren’t. Thanks Lisa and Rich for a wonderful stay!" [](https://expedia.ca/Hiram-Hotels-Log-Home.h113214960.Hotel-Information) ![Forever spring cabin](https://images.trvl-media.com/lodging/24000000/23300000/23299800/23299773/2eb85fc4_y.jpg) ### Forever spring cabin 10/10 Excellent "Beautiful cabin, quiet relaxing stay. Easy and quick response from owners. Highly recommend and will stay again! Thank you! " [](https://expedia.ca/Mesopotamia-Hotels-Forever-Spring-Cabin.h23299773.Hotel-Information) ![Charming Woodside Cabin w/ Private Hot Tub & Scenic Trails at Standing Rock Far](https://images.trvl-media.com/lodging/121000000/120050000/120044900/120044866/2705e0c6_y.jpg) ### Charming Woodside Cabin w/ Private Hot Tub & Scenic Trails at Standing Rock Far 10/10 Excellent "The unit was clean and cozy. A perfect little getaway. " [](https://expedia.ca/Madison-Hotels-Charming-Woodside-Cabin-W-Private-Hot-Tub-Scenic-Trails-At-Standing-Rock-Far.h120044866.Hotel-Information) ![Best Western Park Hotel](https://images.trvl-media.com/lodging/1000000/10000/3100/3047/97f494c2_y.jpg) ### Best Western Park Hotel 10/10 Excellent "The room was clean and generally functional. Breakfast was decent but not great." [](https://expedia.ca/Youngstown-Hotels-Best-Western-Park-Hotel.h3047.Hotel-Information) ![Stay in our cozy Maple Syrup Sugarhouse at Butternut Maple Farm](https://images.trvl-media.com/lodging/104000000/103620000/103612000/103611952/6a44d930_y.jpg) ### Stay in our cozy Maple Syrup Sugarhouse at Butternut Maple Farm 10/10 Excellent "We loved this little place. " [](https://expedia.ca/Stay-In-Our-Cozy-Maple-Syrup-Sugarhouse-At-Butternut-Maple-Farm.h103611952.Hotel-Information) ![Lakefront Haven w/ 50-ft Dock 4BR Near Punderson Park & Amish Country EV Charger](https://images.trvl-media.com/lodging/123000000/122740000/122733100/122733030/4fe012fe_y.jpg) ### Lakefront Haven w/ 50-ft Dock 4BR Near Punderson Park & Amish Country EV Charger 10/10 Excellent "By far the most pleasant and responsive host I have encountered in the dozen or so VRBOs I have stayed at. Keep it up! It's an older, refurbished home which had a few issues which were quickly addressed. I would stay there again. " [](https://expedia.ca/Newbury-Hotels-Lakefront-Haven-W-50-Ft-Dock-4BR-Near-Punderson-Park-Amish-Country-EV-Charger.h122733030.Hotel-Information) ![Country Cottage Farm Stay at Stoneycreek Acres](https://images.trvl-media.com/lodging/19000000/18980000/18970400/18970330/07cd0af1_y.jpg) ### Country Cottage Farm Stay at Stoneycreek Acres 10/10 Excellent "Great time. Molly and family were great." [](https://expedia.ca/Newbury-Hotels-Country-Cottage-Farm-Stay-At-Stoneycreek-Acres.h18970330.Hotel-Information) ![3-bedroom cabin in country setting with AC, WiFi, 15-20 min. to local wineries.](https://images.trvl-media.com/lodging/115000000/114880000/114878800/114878776/1a222835_y.jpg) ### 3-bedroom cabin in country setting with AC, WiFi, 15-20 min. to local wineries. 10/10 Excellent "The cabin is cozy, warm and inviting! It was a great place to stay and recharge! It is very clean and beautifully decorated!" [](https://expedia.ca/3-Bedroom-Cabin-In-Country-Setting-With-AC.h114878776.Hotel-Information) ![The Wildflower - Private cabin in wooded setting](https://images.trvl-media.com/lodging/89000000/88400000/88399500/88399409/cc7f5ca7_y.jpg) ### The Wildflower - Private cabin in wooded setting 10/10 Excellent "Very nice cabin. Clean. We had a little trouble with the tv but we are not tech savvy. " [](https://expedia.ca/Mesopotamia-Hotels-The-Wildflower-Private-Cabin-In-Wooded-Setting.h88399409.Hotel-Information) ## Find out more about Mesopotamia ## Mesopotamia Guest Houses information | Number of reviews | 93 | | ----------------- | -------------- | | Accommodation | 2 Guest Houses | | Lowest Price | CA $211 | | Highest Price | CA $232 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [4 Star Hotels in Middlefield ](https://www.expedia.ca/4Star-Middlefield-Hotels.s40-0-d553248634983583868.Travel-Guide-Filter-Hotels) - [Hotels near Alpine Valley ](https://www.expedia.ca/Alpine-Valley-Hotels.0-l553248621561735299-0.Travel-Guide-Filter-Hotels) - [Aquilla Hotels ](https://www.expedia.ca/Aquilla-Hotels.d553248634983297386.Travel-Guide-Hotels) - [B&B in Burton ](https://www.expedia.ca/Burton-Bed-And-Breakfast.d6341720-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Burton ](https://www.expedia.ca/Burton-Guest-Houses.d6341720-aaGuestHouses.Travel-Guide-Accommodation) - 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