Title: Medical District Vacation Packages | Holiday Packages & Trips 2026/2027 from Expedia.ca [Medical District Travel Guide](https://expedia.ca/Greenville-Medical-District.dx908649044914896896)[Hotels in Medical District](https://expedia.ca/Medical-District-Greenville-Hotels.0-n908649044914896896-0.Travel-Guide-Filter-Hotels)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Medical District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-District.d908649044914896896.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Medical District Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Where to stay in Medical District Find the best Medical District areas and neighborhoods for the activities you enjoy most. [Learn more about Medical District](https://expedia.ca/Greenville-Medical-District.dx908649044914896896) ![Aerial of Downtown Greenville SC South Carolina Skyline](https://images.trvl-media.com/place/908648619872518144/d19e8f2a-6aaf-40a2-a741-559f078407f5.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Uptown Greenville While visiting Uptown Greenville, you might make a stop by sights like Town Common and Greenville Museum of Art. [Find hotel + flight trips in Uptown Greenville](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Uptown%20Greenville&DestID=908648619872518144&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### University District 1 out of top 10 points of interest in this area When in University District, you can plan a visit to Town Common and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area. [Find hotel + flight trips in University District](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=University%20District&DestID=988738433845506048&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Convention District 2 out of top 10 points of interest in this area Convention District might not have many top sights, but 11 Galleria and Clark-LeClair Stadium are two attractions nearby that you can check out. [Find hotel + flight trips in Convention District](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Convention%20District&DestID=988732362615603200&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![durham north carolina](https://images.trvl-media.com/place/944331318232260608/4c34fdbc-0390-4fc3-95ea-8a2c57992e8f.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### College View Historic District When in College View Historic District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area. [Find hotel + flight trips in College View Historic District](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=College%20View%20Historic%20District&DestID=944331318232260608&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Westhaven While Westhaven isn't home to many top sights, 11 Galleria and Clark-LeClair Stadium are some notable places to visit nearby. [Find hotel + flight trips in Westhaven](https://expedia.ca/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Westhaven&DestID=553248635976472882&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ## Medical District Hotel Deals ![Courtyard Marriott Greenville](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/1f6092e1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Courtyard Marriott Greenville 2225 Stantonsburg Rd Greenville NC Fully refundableReserve now, pay when you stay CA $179 CA $202 total Feb 25 - Feb 26 includes taxes & fees 8.6/10 Excellent! (884 reviews) Rooms were nice and the hotel staff very wonderful. Reviewed on Jan 24, 2026 [](https://expedia.ca/Hotel-Search?startDate=25%2F02%2F2026&endDate=26%2F02%2F2026&selected=119042&PinnedHotelID=119042&HadPinnedHotel=true®ionId=908649044914896896) ![Best Western Plus Suites-Greenville](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/d19b7bd8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Plus Suites-Greenville 2310 Greenville Boulevard NE Greenville NC Fully refundableReserve now, pay when you stay CA $149 CA $168 total Feb 11 - Feb 12 includes taxes & fees 8.8/10 Excellent! (1,005 reviews) All the staff were friendly and helpful. The entire hotel was clean, our room immaculate. Reviewed on Jan 31, 2026 [](https://expedia.ca/Hotel-Search?startDate=11%2F02%2F2026&endDate=12%2F02%2F2026&selected=296584&PinnedHotelID=296584&HadPinnedHotel=true®ionId=908649044914896896) ![Staybridge Suites Greenville Medical Center by IHG](https://images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/356f6fc4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Staybridge Suites Greenville Medical Center by IHG 930 Crosswind Street Greenville NC Fully refundable CA $162 CA $183 total Feb 9 - Feb 10 includes taxes & fees 9.2/10 Wonderful! (279 reviews) The room was great and the staff was very friendly. The towels were a little scratchy but other than that no complaints. Reviewed on Feb 3, 2026 [](https://expedia.ca/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=104466390&PinnedHotelID=104466390&HadPinnedHotel=true®ionId=908649044914896896) [See all 180 properties in Medical District](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=08%2F02%2F2026&endDate=09%2F02%2F2026®ionId=908649044914896896) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.