Title: 10 Best Hotels in Medical District, Greenville for 2025 | Expedia.ca

  

[Medical District Travel Guide](https://expedia.ca/Greenville-Medical-District.dx908649044914896896)[Vacation Rentals in Greenville](https://expedia.ca/Greenville-Vacation-Rentals.d2779.Travel-Guide-VacationRentals)[Flights to Greenville](https://expedia.ca/Cheap-Flights-To-Greenville.d2779.Travel-Guide-Flights)[Medical District Car Rentals](https://expedia.ca/Car-Rentals-In-Medical-District.d908649044914896896.Car-Rental-Guide)[Medical District Vacations](https://expedia.ca/Medical-District.d908649044914896896.Destination-Travel-Guides)

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# Hotels in Medical District, Greenville

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## Go beyond your typical stay in Medical District

Family friendly

[](https://www.expedia.ca/Hotel-Search?destination=Medical+District%2C+Greenville%2C+North+Carolina%2C+United+States+of+America&regionId=908649044914896896&latLong=35.608911%2C-77.404095&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&travelerType=family_friendly)

Pool

[](https://www.expedia.ca/Hotel-Search?destination=Medical+District%2C+Greenville%2C+North+Carolina%2C+United+States+of+America&regionId=908649044914896896&latLong=35.608911%2C-77.404095&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=POOL)

Apart­ment

[](https://www.expedia.ca/Hotel-Search?destination=Medical+District%2C+Greenville%2C+North+Carolina%2C+United+States+of+America&regionId=908649044914896896&latLong=35.608911%2C-77.404095&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=APARTMENT)

Pet friendly

[](https://www.expedia.ca/Hotel-Search?destination=Medical+District%2C+Greenville%2C+North+Carolina%2C+United+States+of+America&regionId=908649044914896896&latLong=35.608911%2C-77.404095&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&amenities=PETS)

Cottage

[](https://www.expedia.ca/Hotel-Search?destination=Medical+District%2C+Greenville%2C+North+Carolina%2C+United+States+of+America&regionId=908649044914896896&latLong=35.608911%2C-77.404095&adults=2&startDate=2025-10-24&d1=2025-10-24&endDate=2025-10-26&d2=2025-10-26&lodging=COTTAGE)

## Check prices for these dates

Tonight

[Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=908649044914896896&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Medical District hotels and places to stay

![Reception](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/1f6092e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/2deb739b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/b26d4f63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/120000/119100/119042/99c73073.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Courtyard Marriott Greenville

Medical District

8.8/10

Excellent

(871)

"It was easy to access. Staff was friendly and accomodating. Room was clean and comfortable "

CA $178

CA $201 total

includes taxes & fees

Oct 17 - Oct 18

[](https://www.expedia.ca/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/30d4a3d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/c98c2c60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/e3500d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/1000000/110000/102500/102482/fdb16233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Express Greenville by IHG

0.9 km from Medical District

8.4/10

Very good

(942)

"We will definitely stay there again!"

CA $139

CA $157 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Holiday-Inn-Express-Greenville.h102482.Hotel-Information)

![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/b467b520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/0a7cb5e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/b99bfdac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/1000000/20000/10700/10685/551230eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Baymont by Wyndham Greenville

4.6 km from Medical District

6.4/10

(1000)

"Was kind to allow us to check in at noon which was really appreciated."

CA $85

CA $96 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Greenville-Hotels-Baymont-By-Wyndham-Greenville.h10685.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/67000000/66060000/66051500/66051499/8d31c4e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/67000000/66060000/66051500/66051499/7c4c1e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Accessible](https://images.trvl-media.com/lodging/67000000/66060000/66051500/66051499/ab9c8707.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/67000000/66060000/66051500/66051499/06207e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cypress Inn & Suites Washington by OYO

29.5 km from Medical District

4.4/10

(120)

"Good place to stay for the night before thw Aurora fossil festival. Very affordable"

CA $79

CA $94 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Cypress-Inn-Suites.h66051499.Hotel-Information)

![1 bedroom, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/3fd407a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/ab3838f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/188eeee6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/220000/217400/217352/07e25140.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfort Inn & Suites Greenville Near Convention Center

3.9 km from Medical District

8.6/10

Excellent

(368)

"Great place to stay"

CA $150

CA $170 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Wingate-By-Wyndham-Greenville.h217352.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2557x3y3-9ca87b37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3840h2556x0y4-0c33f88e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3840h2557x0y3-6eee03ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/109000000/108400000/108395100/108395066/w3837h2560x3y0-dfdc5921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Garden INN Greenville University

Uptown Greenville, 2.9 km from Medical District

9.4/10

Exceptional

(78)

"Excellent stay"

CA $182

CA $206 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Hilton-Garden-INN-Greenville-University.h108395066.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/e3b75742.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Two queen beds non smoking](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/9c141e18.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/ea4d109f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/900000/890500/890485/2472bd66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Washington

30.6 km from Medical District

8.2/10

Very good

(637)

"Great facility. Best in Washington "

CA $154

CA $164 total

includes taxes & fees

Nov 6 - Nov 7

[](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Washington.h890485.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/31fb46e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/2da51b79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/2c82a837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/3000000/2600000/2593900/2593867/c60c62e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hampton Inn Greenville

4.1 km from Medical District

9.0/10

Wonderful

(549)

"Nice location, would stay at again "

CA $179

CA $203 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Hampton-Inn-Greenville.h2593867.Hotel-Information)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/d19b7bd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Jetted Tub (Oversized Room;with Sofabed)](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/9f657c06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/f93c58cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/300000/296600/296584/8fc50c3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Best Western Plus Suites-Greenville

6.5 km from Medical District

9.0/10

Wonderful

(1007)

"Nice suites Beautiful hotel"

CA $152

CA $172 total

includes taxes & fees

Oct 26 - Oct 27

[](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Suites-Greenville.h296584.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/03136946.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/9a1f8379.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free continental breakfast](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/d914847d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/21000000/20400000/20392600/20392562/c12cd9d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn & Suites by Marriott Greenville

0.9 km from Medical District

8.8/10

Excellent

(435)

"Location & Clean"

CA $165

CA $187 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville.h20392562.Hotel-Information)

![Suite, 1 Bedroom, Non Smoking, Jetted Tub](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/d55c4c6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/15ae8005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/0f38728e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/70000/62400/62311/5a87c84b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Country Inn & Suites by Radisson, Greenville, NC

5.8 km from Medical District

7.6/10

Good

(794)

"Had a good stay here "

CA $125

CA $143 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Greenville-Hotels-Country-Inn-Suites-By-Radisson.h62311.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/cf612617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/66b44fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room amenity](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/b9bc4a44.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/2000000/1920000/1916900/1916890/58210977.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Candlewood Suites Greenville NC by IHG

2 km from Medical District

8.6/10

Excellent

(575)

"I loved it will visit again "

CA $128

CA $144 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Greenville-Hotels-Candlewood-Suites-Greenville-NC.h1916890.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/8d14df71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/6d7fbebb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/f0182b89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12900/12870/d37ee56a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Holiday Inn Greenville by IHG

4.2 km from Medical District

8.8/10

Excellent

(1001)

"Property was nice and well kept. Breakfast was good though not a lot of choice."

CA $128

CA $144 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Holiday-Inn-Greenville.h12870.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/d6fc4788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/941cb3a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/dbd945d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Individually decorated, individually furnished, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/13600/13542/af549a8d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quality Inn Greenville near University

0.9 km from Medical District

7.4/10

Good

(1001)

"Great staff, safe area, family friendly, thankful for the workout room "

CA $100

CA $113 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-Quality-Inn-Greenville-Near-University.h13542.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/36cd8e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/90561384.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee/tea maker](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/12a39e10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![42-inch Smart TV with cable channels, TV](https://images.trvl-media.com/lodging/91000000/90160000/90153300/90153266/4540394d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Homewood Suites By Hilton Greenville, NC

0.7 km from Medical District

9.4/10

Exceptional

(279)

"Very clean property , good breakfast and very polite and helpful front desk "

CA $154

CA $174 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/589ff6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/d252c390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Laundry room](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/fc9c3679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/21300/21285/7f1e0e96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Motel 6 Greenville, NC – ECU-Medical Center

0.8 km from Medical District

6.6/10

(85)

"It was overall a very great place "

CA $102

CA $116 total

includes taxes & fees

Nov 2 - Nov 3

[](https://www.expedia.ca/Greenville-Hotels-Uptown-Greenville-Hotel.h21285.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/5f6c9580.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/504a2b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/f018a95f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/19000000/18070000/18068600/18068553/7b52f8d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Fairfield Inn and Suites by Marriott Washington

29.7 km from Medical District

9.4/10

Exceptional

(612)

"Nice Hotel! "

CA $165

CA $187 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Greenville-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Washington.h18068553.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/99000000/98410000/98403900/98403868/a05fe940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/99000000/98410000/98403900/98403868/a74dbd7a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/99000000/98410000/98403900/98403868/f067097d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/99000000/98410000/98403900/98403868/d7d8f40b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Economy Inn of Greenville, NC

0.7 km from Medical District

4.6/10

(70)

"Omg. The only time I’ve ever seen a place this bad was on a movie where drug addicts and roaches live. "

CA $78

CA $88 total

includes taxes & fees

Oct 12 - Oct 13

[](https://www.expedia.ca/Greenville-Hotels-1901-Stantonsburg-Rd.h98403868.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/da486ff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/8d83f6a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/116380de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/530000/522700/522664/234da06e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Econo Lodge Greenville

0.9 km from Medical District

7.2/10

Good

(389)

"The hotel was clean and comfy. I would recommend and stay here again."

CA $91

CA $102 total

includes taxes & fees

Oct 23 - Oct 24

[](https://www.expedia.ca/Greenville-Hotels-Econo-Lodge-Greenville.h522664.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/130000/124200/124149/w3000h1998x0y0-7d646def.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/130000/124200/124149/2e78255e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/130000/124200/124149/39d2a5bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/130000/124200/124149/c9a94033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Super 8 by Wyndham Greenville

1.1 km from Medical District

6.6/10

(575)

"The front desk guy was wonderful "

CA $83

CA $94 total

includes taxes & fees

Oct 19 - Oct 20

[](https://www.expedia.ca/Greenville-Hotels-Super-8-By-Wyndham-Greenville.h124149.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25&regionId=908649044914896896&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Where to stay in Medical District

Find the best Medical District areas and neighborhoods for the activities you enjoy most. [Learn more about Medical District](https://www.expedia.ca/Greenville-Medical-District.dx908649044914896896)

-   Uptown Greenville
-   College View Historic District
-   Westhaven
-   Greenville Heights

![](https://mediaim.expedia.com/destination/1/1889c62fff582460c1ba9499992a0d63.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

![](https://mediaim.expedia.com/destination/1/239f2461f762d7a427725a81c593ca1a.jpg?impolicy=fcrop&w=960&h=540&p=1&q=medium)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=908648619872518144)

![Uptown Greenville map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:yqixErghwMs%5C%7DCdAqMoHmBEfAaEy%40%5EzKiSuElBsIRwQ%60DwYP_G%7EIkAmAjE%7B%40bLn%5DrG%7EAxDdAC%60C%7DInKxBdAiCfAUeAvF%60Bv%40sC%7CWyEtY&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=s9WgZJ-ANzT9G02Uu7iNiIlc2T8=)

### Uptown Greenville

While visiting Uptown Greenville, you might make a stop by sights like Town Common and Greenville Museum of Art.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=908648619872518144)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=944331318232260608)

![College View Historic District map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7BbjxEzcfwMyEmCbAaDeKqFPu%40lHnClDwJyC%7DAmA%7CC%7D%40q%40%7CB%7BIgF%7BCXcAbDpAt%40mD%3FgA%5CeAXsAbFtAToBjGlB_%40pA%60FdDuP%7Ei%40&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=0BESo8X4PcRQsIcIShCSIIeOH3k=)

### College View Historic District

When in College View Historic District, you can plan a visit to Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium, some noteworthy sights in the nearby area.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=944331318232260608)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976472882)

![Westhaven map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:uo%60xEvfmwMoNeBi%40i%40a%40kHyJN%7DQcWMaG%5Bi%40mAs%40uNQSYMmBw%40_BsCoMFkDZa%40vEOTkO%60Qj%40vBQh%40iYj%60%40dLX%5EMrDrAl%40FrEi%40hC%7ECpCbCzGZrVbCvNKdAeCz%40FhUi%40fG&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=ZwpQkNffr01a15IZgckj5QKEGH8=)

### Westhaven

While Westhaven isn't home to many top sights, 11 Galleria and Arlington Crossing are some notable places to visit nearby.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976472882)

[](https://www.expedia.ca/Hotel-Search?pwaOverlay=map&regionId=553248635976482373)

![Greenville Heights map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:itjxElriwM%7B%5E%7DBg%40wPVuJtb%40jGeAbOVb%40%5DN%5DfF&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=EpbKgdsJmGPQt7w0uQlQ2T0zXSo=)

### Greenville Heights

When in Greenville Heights, you can plan a visit to Town Common and Williams Arena at Minges Coliseum, some noteworthy sights in the nearby area.

[See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976482373)

## Top Medical District Hotel Reviews

![Microtel Inn & Suites by Wyndham Greenville/University Medic](//images.trvl-media.com/lodging/3000000/2010000/2009600/2009531/2e252281_y.jpg)

### Microtel Inn & Suites by Wyndham Greenville/University Medic

10/10 Excellent

"Everything was well prepared and clean. Me and my girlfriend appreciate the black lady at the desk for being so polite with us as we had some issues before arrriving."

[](https://expedia.ca/Greenville-Hotels-Microtel-Inn-Suites-By-Wyndham-GreenvilleUniversity-Medic.h2009531.Hotel-Information)

![Comfort Inn & Suites Greenville Near Convention Center](//images.trvl-media.com/lodging/1000000/220000/217400/217352/2d5a6141_y.jpg)

### Comfort Inn & Suites Greenville Near Convention Center

10/10 Excellent

"Nice staff and convenient location perfect for short term. "

[](https://expedia.ca/Greenville-Hotels-Wingate-By-Wyndham-Greenville.h217352.Hotel-Information)

![Holiday Inn Express Greenville by IHG](//images.trvl-media.com/lodging/1000000/110000/102500/102482/30d4a3d9_y.jpg)

### Holiday Inn Express Greenville by IHG

10/10 Excellent

"Staff was friendly!"

[](https://expedia.ca/Greenville-Hotels-Holiday-Inn-Express-Greenville.h102482.Hotel-Information)

![Staybridge Suites Greenville Medical Center by IHG](//images.trvl-media.com/lodging/105000000/104470000/104466400/104466390/356f6fc4_y.jpg)

### Staybridge Suites Greenville Medical Center by IHG

10/10 Excellent

"Everything was wonderful "

[](https://expedia.ca/Greenville-Hotels-Staybridge-Suites-Greenville-Medical-Center.h104466390.Hotel-Information)

![Quality Inn Greenville near University](//images.trvl-media.com/lodging/1000000/20000/13600/13542/dbd945d2_y.jpg)

### Quality Inn Greenville near University

10/10 Excellent

"I expected this to be "

[](https://expedia.ca/Greenville-Hotels-Quality-Inn-Greenville-Near-University.h13542.Hotel-Information)

![Residence Inn by Marriott Greenville](//images.trvl-media.com/lodging/7000000/6060000/6057700/6057673/f8514e6b_y.jpg)

### Residence Inn by Marriott Greenville

10/10 Excellent

"The establishment was clean. The staff was absolutely amazing. I would definitely recommend this location tonight at 10 I will be returning"

[](https://expedia.ca/Greenville-Hotels-Residence-Inn-Greenville.h6057673.Hotel-Information)

![Best Western Plus Suites-Greenville](//images.trvl-media.com/lodging/1000000/300000/296600/296584/d19b7bd8_y.jpg)

### Best Western Plus Suites-Greenville

10/10 Excellent

"If you don’t like the smell of fabuloso stay away! Hotel has been updated, clean, comfortable beds, nice size rooms, good breakfast. Staff not very friendly and you MUST be out by 11am! "

[](https://expedia.ca/Greenville-Hotels-Best-Western-Plus-Suites-Greenville.h296584.Hotel-Information)

![Hampton Inn Washington](//images.trvl-media.com/lodging/1000000/900000/890500/890485/e3b75742_y.jpg)

### Hampton Inn Washington

10/10 Excellent

"Great facility. Best in Washington "

[](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Washington.h890485.Hotel-Information)

![Affordable Suites Greenville](//images.trvl-media.com/lodging/3000000/2690000/2682700/2682635/41b082ee_y.jpg)

### Affordable Suites Greenville

10/10 Excellent

"Clean, comfortable, spacious room. Well lit parking lot. Lady at front desk was very courteous and professional. Would stay again."

[](https://expedia.ca/Greenville-Hotels-Affordable-Suites.h2682635.Hotel-Information)

## Frequently asked questions

### What is Medical District like?

> Travelers are sure to enjoy a stay in Greenville's Medical District neighborhood. Consider a visit to Laupus Health Sciences Library as part of your Medical District travel plans.

### Where is the best place to stay in Medical District?

> Based on Expedia customer reviews, [Courtyard Marriott Greenville](https://www.expedia.ca/Greenville-Hotels-Courtyard-Marriott-Greenville.h119042.Hotel-Information) is the highest ranked property in Medical District. This hotel offers a restaurant and free parking.

### If I need to cancel my hotel reservation in Medical District, will I receive a refund?

> Yes, most hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get top deals in Medical District.

### What can I see and do in this Greenville neighborhood?

> Laupus Health Sciences Library is an attraction you might want to check out while you're in Medical District. When you're sightseeing in Greenville, North Pines and Guy Smith Stadium are also worth a stop.

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-   [Flights from Simpson](https://www.expedia.ca/lp/flights/553248634998830009/flights-from-simpson)
-   [Flights from Pinetops](https://www.expedia.ca/lp/flights/553248634999169729/flights-from-pinetops)
-   [Flights from Bellingham (BLI) to Greenville (PGV)](https://www.expedia.ca/lp/flights/bli/pgv/bellingham-to-greenville)
-   [Flights from Concord (CON) to Greenville (PGV)](https://www.expedia.ca/lp/flights/con/pgv/concord-to-greenville)
-   [Flights from Dubuque (DBQ) to Greenville (PGV)](https://www.expedia.ca/lp/flights/dbq/pgv/dubuque-to-greenville)
-   [Flights from Niagara Falls (IAG) to Greenville (PGV)](https://www.expedia.ca/lp/flights/iag/pgv/niagara-falls-to-greenville)
-   [Flights from New York (JFK) to Greenville (PGV)](https://www.expedia.ca/lp/flights/jfk/pgv/new-york-to-greenville)
-   [Flights from Laredo (LRD) to Greenville (PGV)](https://www.expedia.ca/lp/flights/lrd/pgv/laredo-to-greenville)
-   [Flights from Seattle (SEA) to Greenville (PGV)](https://www.expedia.ca/lp/flights/sea/pgv/seattle-to-greenville)
-   [Flights from Singapore (SIN) to Greenville (PGV)](https://www.expedia.ca/lp/flights/sin/pgv/singapore-to-greenville)
-   [Flights from Edmonton (YEG) to Greenville (PGV)](https://www.expedia.ca/lp/flights/yeg/pgv/edmonton-to-greenville)
-   [Flights from Hamilton (YHM) to Greenville (PGV)](https://www.expedia.ca/lp/flights/yhm/pgv/hamilton-to-greenville)
-   [Flights from Halifax (YHZ) to Greenville (PGV)](https://www.expedia.ca/lp/flights/yhz/pgv/halifax-to-greenville)
-   [Flights from Kelowna (YLW) to Greenville (PGV)](https://www.expedia.ca/lp/flights/ylw/pgv/kelowna-to-greenville)
-   [Flights from Montreal (YUL) to Greenville (PGV)](https://www.expedia.ca/lp/flights/yul/pgv/montreal-to-greenville)
-   [Flights from Winnipeg (YWG) to Greenville (PGV)](https://www.expedia.ca/lp/flights/ywg/pgv/winnipeg-to-greenville)
-   [Flights from Calgary (YYC) to Greenville (PGV)](https://www.expedia.ca/lp/flights/yyc/pgv/calgary-to-greenville)
-   [Flights from Toronto (YYZ) to Greenville (PGV)](https://www.expedia.ca/lp/flights/yyz/pgv/toronto-to-greenville)

-   [Visit Uptown Greenville](https://www.expedia.ca/Greenville-Uptown-Greenville.dx908648619872518144)

-   [Car rental Greenville](https://www.expedia.ca/Car-Rentals-In-Greenville.d2779.Car-Rental-Guide)
-   [Car rental House](https://www.expedia.ca/Car-Rentals-In-House.d553248635975848958.Car-Rental-Guide)
-   [Rental cars Pitt-Greenville airport](https://www.expedia.ca/Car-Rentals-In-Pitt-Greenville.d5654352.Car-Rental-Guide)
-   [Enterprise Rental Cars in Pitt-Greenville](https://www.expedia.ca/Enterprise-Car-Rentals-In-Pitt-Greenville.d5654352-c15.Car-Rental-Guide-Suppliers)
-   [Sixt Rental Cars in Pitt-Greenville](https://www.expedia.ca/Sixt-Car-Rentals-In-Pitt-Greenville.d5654352-c35.Car-Rental-Guide-Suppliers)

-   [Greenville Vacation Rentals](https://www.expedia.ca/Greenville-Vacation-Rentals.d2779.Travel-Guide-VacationRentals)

-   [Book Hotels in Medical District on Expedia.com](https://www.expedia.com/Medical-District-Greenville-Hotels.0-n908649044914896896-0.Travel-Guide-Filter-Hotels)

-   Explore a world of travel with Expedia

### Hotels in top Greenville neighborhoods

-   [Hotels in Uptown Greenville](https://expedia.ca/Uptown-Greenville-Greenville-Hotels.0-n908648619872518144-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Medical District](https://expedia.ca/Medical-District-Greenville-Hotels.0-n908649044914896896-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Westhaven](https://expedia.ca/Westhaven-Greenville-Hotels.0-n553248635976472882-0.Travel-Guide-Filter-Hotels)
-   [Hotels in Greenville Heights](https://expedia.ca/Greenville-Heights-Greenville-Hotels.0-n553248635976482373-0.Travel-Guide-Filter-Hotels)

### Hotels near popular Greenville Attractions

-   [Hotels near ECU Health Medical Center](https://expedia.ca/ECU-Health-Medical-Center-Hotels.0-l6221234-0.Travel-Guide-Filter-Hotels)
-   [Hotels near East Carolina University](https://expedia.ca/East-Carolina-University-Hotels.0-l6221225-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Greenville VA Medical Center](https://expedia.ca/Greenville-VA-Medical-Center-Hotels.0-l553248621559275873-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Dowdy–Ficklen Stadium](https://expedia.ca/DowdyFicklen-Stadium-Hotels.0-l553248622006979884-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Greenville North Carolina Convention Center](https://expedia.ca/Greenville-North-Carolina-Convention-Center-Hotels.0-l811185100508377088-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Rock Springs Center](https://expedia.ca/Rock-Springs-Center-Hotels.0-l808984002366144512-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Deadwood](https://expedia.ca/Deadwood-Hotels.0-l553248621532661302-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Bradford Creek Golf Club](https://expedia.ca/Bradford-Creek-Golf-Club-Hotels.0-l553248621532661299-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Clark-LeClair Stadium](https://expedia.ca/Clark-LeClair-Stadium-Hotels.0-l811364008704397312-0.Travel-Guide-Filter-Hotels)

### More Accommodation Types in Medical District

-   [Vacation Homes in Greenville](https://expedia.ca/Greenville-Private-Vacation-Homes.d2779-aaPrivateVacationHomes.Travel-Guide-Accommodation)
-   [Apartments in Greenville](https://expedia.ca/Greenville-Apartments.d2779-aaApartments.Travel-Guide-Accommodation)
-   [Cottages in Greenville](https://expedia.ca/Greenville-Cottages.d2779-aaCottages.Travel-Guide-Accommodation)
-   [Condo Rentals in Greenville](https://expedia.ca/Greenville-Condos.d2779-aaCondos.Travel-Guide-Accommodation)
-   [Motels in Greenville](https://expedia.ca/Greenville-Motels.d2779-aaMotels.Travel-Guide-Accommodation)
-   [Cabin Rentals in Greenville](https://expedia.ca/Greenville-Cabins.d2779-aaCabins.Travel-Guide-Accommodation)
-   [Farmstay in Greenville](https://expedia.ca/Greenville-Agritourism.d2779-aaAgritourism.Travel-Guide-Accommodation)
-   [B&B in Greenville](https://expedia.ca/Greenville-Bed-And-Breakfast.d2779-aaBedAndBreakfast.Travel-Guide-Accommodation)
-   [Guest Houses in Greenville](https://expedia.ca/Greenville-Guest-Houses.d2779-aaGuestHouses.Travel-Guide-Accommodation)
-   [Inns in Greenville](https://expedia.ca/Greenville-Inns.d2779-aaInns.Travel-Guide-Accommodation)

### Medical District Hotels by Star Rating

-   [2 Star Hotels in Medical District](https://expedia.ca/2Star-Medical-District-Greenville-Hotels.s20-n908649044914896896-0.Travel-Guide-Filter-Hotels)
-   [3 Star Hotels in Medical District](https://expedia.ca/3Star-Medical-District-Greenville-Hotels.s30-n908649044914896896-0.Travel-Guide-Filter-Hotels)

### Medical District Hotels by Brand

-   [Independent Hotels](https://expedia.ca/Medical-District-Greenville-Hotels-Independent.0-n908649044914896896-0--bIndependent.Travel-Guide-Filter-Hotels)

### Explore more hotels

-   [Homewood Suites By Hilton Greenville, NC](https://expedia.ca/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville.h90153266.Hotel-Information)
-   [Hampton Inn Greenville](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Greenville.h2593867.Hotel-Information)
-   [Fairfield Inn and Suites by Marriott Washington](https://expedia.ca/Greenville-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Washington.h18068553.Hotel-Information)
-   [Affordable Suites Greenville](https://expedia.ca/Greenville-Hotels-Affordable-Suites.h2682635.Hotel-Information)
-   [Hampton Inn Washington](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Washington.h890485.Hotel-Information)
-   [Residence Inn by Marriott Greenville](https://expedia.ca/Greenville-Hotels-Residence-Inn-Greenville.h6057673.Hotel-Information)
-   [Super 8 by Wyndham Greenville](https://expedia.ca/Greenville-Hotels-Super-8-By-Wyndham-Greenville.h124149.Hotel-Information)
-   [Fairfield Inn & Suites by Marriott Greenville](https://expedia.ca/Greenville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville.h20392562.Hotel-Information)
-   [Hilton Greenville](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h1575.Hotel-Information)
-   [Red Roof Inn Greenville, NC](https://expedia.ca/Greenville-Hotels-Red-Roof-Inn-Greenville.h40380.Hotel-Information)
-   [Motel 6 Greenville, NC – ECU-Medical Center](https://expedia.ca/Greenville-Hotels-Uptown-Greenville-Hotel.h21285.Hotel-Information)
-   [Candlewood Suites Greenville NC by IHG](https://expedia.ca/Greenville-Hotels-Candlewood-Suites-Greenville-NC.h1916890.Hotel-Information)

[See a list of all hotels in Greenville](https://expedia.ca/All-Greenville-Hotels.d2779.Travel-Guide-City-All-Hotels)

### More ways to book

-   [Book Hotels in Medical District on Expedia.com](https://www.expedia.com/Medical-District-Greenville-Hotels.0-n908649044914896896-0.Travel-Guide-Filter-Hotels)

### Expedia's Latest Trends

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-   [Vernon Cheap Hotels](https://expedia.ca/Vernon-Hotels-Cheap-Hotels.0-0-d10619-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Holiday Inn Express & Suites Saskatoon by IHG](https://expedia.ca/Saskatoon-Hotels-Holiday-Inn-Express-Suites-Saskatoon.h900498.Hotel-Information)
-   [Salt Shaker Deli & Inn](https://expedia.ca/Lunenburg-Hotels-Salt-Shaker-Deli-Inn.h11715927.Hotel-Information)
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-   [Luxury Family Oasis W/ GameRoom/Hot Tub & 10 Min Walk to Falls & Clifton Hill](https://expedia.ca/Niagara-Falls-Hotels-Luxury-Farmhouse-Family-Oasis-W-GameRoomKing-BedHot-Tub.h90169443.Hotel-Information)
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Flights

-   [Flights from Vancouver to Winnipeg](https://expedia.ca/lp/flights/yvr/ywg/vancouver-to-winnipeg)
-   [Cheap Flights to Philippines](https://expedia.ca/Destinations-In-Philippines.d145.Flight-Destinations)
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-   [Flights from Vancouver to Barcelona](https://expedia.ca/lp/flights/yvr/bcn/vancouver-to-barcelona)
-   [Flights from Toronto to Bujumbura](https://expedia.ca/lp/flights/yyz/bjm/toronto-to-bujumbura)
-   [Flights from New York to Toronto](https://expedia.ca/lp/flights/lga/yyz/new-york-to-toronto)

Packages

-   [Dubai Trip](https://expedia.ca/Dubai.d1079.Destination-Travel-Guides)
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Vacation Rentals

-   [Rentals in The Villages](https://expedia.ca/The-Villages-Vacation-Rentals.d6053731.Travel-Guide-VacationRentals)