Title: The 10 Best Hotels Near Mcleod Regional Medical Center, Florence from CA $73 | Expedia.ca [Vacation Rentals in Florence](https://expedia.ca/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Mcleod Regional Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide)[Mcleod Regional Medical Center Vacations](https://expedia.ca/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) ![Florence_McleodRegionalMedicalCenter_6162127_0006](https://images.trvl-media.com/place/6162127/fc91dc39-457a-4bce-865f-7d732cbd43f6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels near Mcleod Regional Medical Center, Florence from CA $73 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 10 - Oct 11](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2025-10-10&endDate=2025-10-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 11 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2025-10-11&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Top Hotels Close to Mcleod Regional Medical Center ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Bedrooms (Penthouse)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/20c926f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/9a944163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/5b020e41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Florence, Tapestry Collection by Hilton 0.8 km from Mcleod Regional Medical Center 8.8/10 Excellent (586) "Really nice, really pretty, friendly staff , lovely stay " CA $183 CA $205 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/bee831df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/ad4579b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown 0.8 km from Mcleod Regional Medical Center 8.8/10 Excellent (1008) "There is a great restaurant called Town Hall across the street. It is the absolute best place to eat." CA $140 CA $157 total includes taxes & fees Nov 3 - Nov 4 [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118990000/118982900/118982850/8e3233ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Florence Downtown 1.2 km from Mcleod Regional Medical Center 6.0/10 (2) "Good" CA $63 CA $73 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Florence-Hotels-Rodeway-Inn.h118982850.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/2d22b260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/dd4c54c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Accessible bathroom](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/6df09eae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/861500/861452/097baa2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Florence 4.8 km from Mcleod Regional Medical Center 6.8/10 (1001) "Pleasant stay " CA $79 CA $89 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Super-8-By-Wyndham-Florence.h861452.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/0980cab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/611a193a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/bb2eaca3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/a7359212.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Florence, SC 5.3 km from Mcleod Regional Medical Center 6.4/10 (603) "Friendly staff the right location " CA $76 CA $85 total includes taxes & fees Oct 11 - Oct 12 [](https://www.expedia.ca/Florence-Hotels-Motel-6-Florence.h898902.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/b1bbd639.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/dab62d55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/65e0bac5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North 5.9 km from Mcleod Regional Medical Center 6.8/10 (1005) "Clean room Nice staff Good area Plenty of food places to eat Air conditioning worked great Nice place" CA $83 CA $93 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Iron/ironing board, rollaway beds, bed sheets](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/ea58653f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed with Sofa bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/3252d1d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/5dcc1481.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/190000/180100/180086/ab8d3cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge 5.1 km from Mcleod Regional Medical Center 5.8/10 (1000) "Alot of foot traffic between neighboring hotel and drugs. " CA $77 CA $86 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Econo-Lodge.h180086.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/1000000/920000/911400/911306/d6be6ae2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/920000/911400/911306/a530f92d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/920000/911400/911306/af016f21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/1000000/920000/911400/911306/a60c1179.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Suburban Studios Florence I-95 5.1 km from Mcleod Regional Medical Center 5.6/10 (574) "Dresser drawer was broken apart, bathroom door would not close, badly worn bed linens, holes in carpet and bedspreads, microwave did not function properly. Room was clean, quiet, safe, no bed bugs, bathroom recently refitted." CA $72 CA $82 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Florence-Hotels-Suburban-Extended-Stay-Hotel.h911306.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Accessible, Non Smoking | Bathroom shower](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/7046523d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/2d26ec35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/73965d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence 6.1 km from Mcleod Regional Medical Center 6.6/10 (1003) "This our usual hotel we stay everyone were in the area." CA $74 CA $83 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13400/13359/541e5541.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/13400/13359/cb66cb4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13400/13359/395140c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/13400/13359/b64c30bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clarion Inn & Suites 5 km from Mcleod Regional Medical Center 4.4/10 (288) "It appears the property is under new management and possible being updated. The room was very inexpensive and the staff charge a deposit refundable typically 3-5 business days almost as much as room cost. My room was prepaid before I arrived. " CA $77 CA $86 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Florence-Hotels-Clarion-Inn-Suites.h13359.Hotel-Information) ![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/a269d3f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/ada13811.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Room, 1 King Bed (Smoke Free) | Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/3d1c0a4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/222a1b80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center 6.9 km from Mcleod Regional Medical Center 6.8/10 (1003) "Close to favorite restaurants." CA $79 CA $88 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/1b5fb4c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d2976b97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/d1f8ba02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11800/11724/ffb23f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence Near Civic Center 7.5 km from Mcleod Regional Medical Center 6.8/10 (1005) "Overall the check in time & process online was easy and fast." CA $90 CA $101 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-Florence-Near-Civic-Center.h11724.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/bae8a99a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/b20afe52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/032ee4dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/75000000/74430000/74425300/74425295/d6901bf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites 5 km from Mcleod Regional Medical Center 3.6/10 (76) "Simple place to stay, I get they are under construction but there was no breakfast or pool or fitness room as advertised. " CA $106 CA $119 total includes taxes & fees Oct 16 - Oct 17 [](https://www.expedia.ca/Florence-Hotels-MainStay-Suites.h74425295.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/cf2a0e95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/665dfc6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/806e5cac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/68000000/67640000/67630500/67630478/65b1123b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio 6 Florence , SC 5.3 km from Mcleod Regional Medical Center 3.2/10 (5) CA $77 CA $86 total includes taxes & fees Oct 11 - Oct 12 [](https://www.expedia.ca/Florence-Hotels-Studio-6-Florence.h67630478.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/f3055d4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Room, 1 Queen Bed, Accessible | Bathroom](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/b7213dd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/44ec11f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/1ae2912b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Florence Inn and Suites 11.2 km from Mcleod Regional Medical Center 6.4/10 (317) "We had a good experience here. Staff very helpful " CA $76 CA $85 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/098e0775.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/ebe19db6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/078b0644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/530000/528200/528148/18421e39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Florence SC I-95 North / Hwy 76 11 km from Mcleod Regional Medical Center 5.0/10 (343) "Nice hotel" CA $73 CA $82 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Travelodge-By-Wyndham-Florence.h528148.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/2000000/1090000/1080600/1080506/67faa68f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1090000/1080600/1080506/6cf4fd83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/2000000/1090000/1080600/1080506/8ea49843.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds](https://images.trvl-media.com/lodging/2000000/1090000/1080600/1080506/03489f7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Raceway Inn 15.1 km from Mcleod Regional Medical Center 5.8/10 (48) "Good for the INN, AC quiet, clean and most important no smell in the room. " CA $90 CA $99 total includes taxes & fees Oct 20 - Oct 21 [](https://www.expedia.ca/Florence-Hotels-Raceway-Inn.h1080506.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/1000000/10000/500/455/7442eef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn 4.7 km from Mcleod Regional Medical Center 7.6/10 Good (1003) "Nice staff, clean rooms, easy access." CA $111 CA $124 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/51d8f371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC 5.5 km from Mcleod Regional Medical Center 9.0/10 Wonderful (2146) "Great stay" CA $133 CA $149 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/ebea43b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence 5.5 km from Mcleod Regional Medical Center 8.8/10 Excellent (2392) "Great stay" CA $92 CA $103 total includes taxes & fees Oct 12 - Oct 13 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-24&endDate=2025-10-25®ionId=6162127&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMcleod-Regional-Medical-Center-Hotels.0-l6162127-0.Travel-Guide-Filter-Hotels) ## Top Mcleod Regional Medical Center Hotel Reviews ![Comfort Inn & Suites](//images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites 10/10 Excellent "Friendly staff, clean rooms, comfortable beds, nice breakfast. Just a very nice hotel experience. Will definitely stay here again. " [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hyatt Place Florence Downtown](//images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "The room was clean and only a few years old. Staff could not be any more pleasant. Lot's of nice places to eat very close (walk) without any worries. " [](https://expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![TownePlace Suites by Marriott Florence](//images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "Staff super friendly " [](https://expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](//images.trvl-media.com/lodging/1000000/20000/15500/15497/b1bbd639_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 10/10 Excellent "Didn’t have any issues." [](https://expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Tru by Hilton Florence I-95](//images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "Neat place very trendy and comfortable" [](https://expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Howard Johnson by Wyndham Florence](//images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Clean room" [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Residence Inn Marriott Florence](//images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb_y.jpg) ### Residence Inn Marriott Florence 10/10 Excellent "Everything was very nice and the staff was very friendly. " [](https://expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Park Inn by Radisson Florence, SC](//images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "It is a good clean place to sleep. Staff is nice" [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Best Western Inn](//images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf_y.jpg) ### Best Western Inn 10/10 Excellent "Clean room , Small bathroom " [](https://expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ## Hotels near other Mcleod Regional Medical Center attractions [](https://www.expedia.ca/Florence-Museum-Hotels.0-l6162137-0.Travel-Guide-Filter-Hotels) ![Florence_FlorenceMuseum_6162137_0005](https://images.trvl-media.com/place/6162137/dd0f8253-2cfa-4203-89de-823ddac9605e.jpg) ### Florence Museum 3.8/5 (122 reviews) You can spend time browsing the exhibits at Florence Museum in Florence. While in this trendy area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6162137) [](https://www.expedia.ca/Magnolia-Mall-Hotels.0-l6165602-0.Travel-Guide-Filter-Hotels) ![Florence_MagnoliaMall_6165602_0005](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg) ### Magnolia Mall 4.0/5 (410 reviews) You can enjoy retail therapy at Magnolia Mall during your visit to Florence. While in this trendy area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6165602) [](https://www.expedia.ca/Drs-Bruce-And-Lee-Foundation-Library-Hotels.0-l950929591644532736-0.Travel-Guide-Filter-Hotels) ### Drs Bruce and Lee Foundation Library Learn about the local history of Florence when you spend time at Drs Bruce and Lee Foundation Library. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950929591644532736) [](https://www.expedia.ca/War-Between-The-States-Museum-Hotels.0-l950930659214794752-0.Travel-Guide-Filter-Hotels) ### War Between the States Museum You can spend an afternoon exploring the galleries in War Between the States Museum during your travels in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950930659214794752) [](https://www.expedia.ca/Dr-Eddie-Floyd-Tennis-Center-Hotels.0-l941624453535023104-0.Travel-Guide-Filter-Hotels) ### Dr. Eddie Floyd Tennis Center Catch an event at Dr. Eddie Floyd Tennis Center during your trip to Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624453535023104) [](https://www.expedia.ca/South-Park-Hotels.0-l911207011182792704-0.Travel-Guide-Filter-Hotels) ### South Park South Park is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911207011182792704) [](https://www.expedia.ca/Old-Greenwood-Athletic-Park-Hotels.0-l911210743347908608-0.Travel-Guide-Filter-Hotels) ### Old Greenwood Athletic Park After visiting Old Greenwood Athletic Park, make a plan to see the other sights and activities in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911210743347908608) [](https://www.expedia.ca/Florence-Veterans-Park-Hotels.0-l619470572411232256-0.Travel-Guide-Filter-Hotels) ### Florence Veterans Park Explore the great outdoors at Florence Veterans Park, a lovely green space in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=619470572411232256) ## Frequently asked questions ### What are the top-rated hotels near Mcleod Regional Medical Center? > Finding the perfect stay near Mcleod Regional Medical Center is essential for a comfortable visit. Here are some top-rated hotels in Florence, South Carolina that cater to travellers looking for convenience and quality. > > > > [Affordable Suites Florence](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) > > > > Affordable Suites Florence is a welcoming choice for travellers, located just 7.4 km from Mcleod Regional Medical Center and an impressive review rating of 9.4. This hotel features essential amenities such as air conditioning for comfort and self-parking options, including free uncovered parking. Guests appreciate the accessibility features, making it a convenient option for all travellers. > > > > [Comfort Inn & Suites](https://expedia.ca/Florence-hotels-Comfort-Inn-&-Suites.h38336321.Hotel-information) > > > > Comfort Inn & Suites offers a comfortable stay just 7.9 km from Mcleod Regional Medical Center, rated 9.2 by travellers. This hotel is well-equipped with amenities like a 24-hour fitness centre and a refreshing accessible pool. Guests can start their day with a complimentary daily breakfast, including continental options, and enjoy the convenience of a microwave in their rooms. The inviting atmosphere and thoughtful amenities make it a great choice for those visiting the area. > > > > [TownePlace Suites by Marriott Florence](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) > > > > TownePlace Suites by Marriott Florence presents a delightful experience with a review rating of 9.0 and a solid 3-star rating, located 7.7 km from Mcleod Regional Medical Center. This hotel stands out with its spacious suites featuring kitchens equipped with stovetops, refrigerators, and dishwashers, ideal for longer stays. Guests can unwind at the outdoor pool or enjoy a complimentary buffet breakfast each morning. The rooftop garden adds a unique touch, offering a serene space for relaxation. ### What hotels are within walking distance to Mcleod Regional Medical Center? > Discover excellent accommodations just a short stroll from Mcleod Regional Medical Center, perfect for travellers seeking comfort and convenience. > > > > [Hotel Florence, Tapestry Collection by Hilton](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) > > > > Hotel Florence, Tapestry Collection by Hilton is a charming 3-star hotel located just a 6-minute walk from Mcleod Regional Medical Center. With a review rating of 8.8, this hotel offers travellers a range of luxurious amenities including a full-service spa featuring massage treatments, aromatherapy, and a fitness centre open 24 hours. Guests can indulge in various body treatments or relax in bathrobes with designer toiletries provided. The historical district location adds a unique touch to the stay, making it an inviting choice for travellers looking for relaxation and convenience. > > > > [Hyatt Place Florence Downtown](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) > > > > Hyatt Place Florence Downtown is a modern 3-star hotel situated just 7 minutes away on foot from Mcleod Regional Medical Center. Rated 8.8 by travellers, this hotel features a refreshing outdoor pool and a fitness centre available around the clock. Guests can enjoy a complimentary breakfast daily, including options for weekends, as well as a 24-hour restaurant. The comfortable rooms, equipped with sofa beds, ensure a cozy stay, making it a practical choice for those visiting the area. ### How much is a hotel near Mcleod Regional Medical Center? > Staying near Mcleod Regional Medical Center is a treat, with plenty of hotels from CA $73 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, especially in peak season. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during weekends or around public holidays. ### What are the most popular family-friendly hotels near Mcleod Regional Medical Center? > For families visiting Mcleod Regional Medical Center, finding the perfect family-friendly hotel is key to a comfortable stay in Florence. Here are some top-rated options that cater to families' needs. > > > > [Aloft Florence](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) > > > > Aloft Florence is a delightful 3-star hotel located just 7.9 km from Mcleod Regional Medical Center, with a strong travellers' rating of 8.4. This family-friendly hotel offers amenities like an indoor pool, free cribs, and connecting rooms, ensuring a comfortable stay for travellers of all ages. Kids will enjoy the arcade game room, while parents will appreciate the daily housekeeping and fitness facilities available 24 hours. > > > > [Comfort Suites Florence I-95](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) > > > > Comfort Suites Florence I-95, located 6.6 km from Mcleod Regional Medical Center, boasts a solid review rating of 8.4. This family-friendly hotel features accessible indoor pool facilities and complimentary breakfast, making it easy to start the day right. Guests can take advantage of connecting rooms and in-room microwaves, ensuring a convenient and enjoyable stay for families. > > > > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > > Best Western Inn is a welcoming option just 5.0 km from Mcleod Regional Medical Center, rated by travellers at 7.6. Families will appreciate the accessibility of the pool and the availability of free cribs and connecting rooms. With a complimentary continental breakfast and a secured pool area, this hotel is designed to cater to the needs of families looking for a comfortable stay. ### Are there any hotels with pools close to Mcleod Regional Medical Center? > If you're looking for top-rated hotels with pools near Mcleod Regional Medical Center, Florence has some excellent options for a refreshing stay. > > > > [Aloft Florence](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) > > > > Aloft Florence is situated 7.9 km from Mcleod Regional Medical Center and boasts an impressive review rating of 8.4. This 3-star hotel features a 24-hour indoor pool accessible to all travellers. Additional offerings include a fitness centre, arcade game room, and complimentary amenities for children, creating a fun and engaging environment for families. > > > > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > > Located only 5.0 km from Mcleod Regional Medical Center, Best Western Inn provides a welcoming atmosphere with a shared outdoor pool, rated by travellers at 7.6. This hotel offers accessible pool facilities along with complimentary breakfast and free self-parking, ensuring convenience for all travellers. Its comfortable accommodations and amenities like cribs and premium bedding make it a great choice for families. > > > > [Residence Inn Marriott Florence](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) > > > > Just 7.7 km from Mcleod Regional Medical Center, the 3-star Residence Inn Marriott Florence offers a delightful outdoor pool experience for travellers. With a great traveler rating score of 8.8, this hotel features sun loungers, umbrellas, and a gated pool area, ensuring a relaxing environment. Additional amenities include free breakfast, a hot tub, and spacious suites with kitchens, making it ideal for families and extended stays. ### What are the best pet-friendly hotels near Mcleod Regional Medical Center? > For travellers seeking pet-friendly accommodations near Mcleod Regional Medical Center, Florence offers some great options that ensure both you and your furry friends have a comfortable stay. > > > > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > > Best Western Inn is situated only 5.0 km from Mcleod Regional Medical Center and features a favorable traveler rating of 7.6. This pet-friendly hotel welcomes dogs and cats, making it a comfortable choice for travellers with pets. Guests can indulge in free breakfast, enjoy the outdoor pool, and take advantage of the early check-in and late check-out options, ensuring a pleasant stay for both you and your furry companions. > > > > [La Quinta Inn & Suites by Wyndham Florence](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) > > > > La Quinta Inn & Suites by Wyndham Florence is a welcoming 3-star hotel located just 5.8 km from Mcleod Regional Medical Center. Rated by travellers with a solid 8.0, this hotel is ideal for pet owners, offering pet-friendly amenities including in-room pet access and designated areas for pets. Guests can enjoy a range of conveniences such as free breakfast, a fitness centre, and an outdoor pool, making it a great choice for families and those needing a relaxing getaway. > > > > [Red Roof Inn Florence - Civic Center](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) > > > > Red Roof Inn Florence - Civic Center is located 7.2 km from Mcleod Regional Medical Center, with a review rating of 6.8. This budget-friendly hotel is pet-friendly, allowing pets in rooms, and is perfect for travellers traveling with their four-legged pals. The hotel features essential amenities like a kitchenette, free toiletries, and convenient self-parking, making it a practical choice for those seeking affordability and comfort. ### Can I book a fully refundable hotel close to Mcleod Regional Medical Center? > Most bookings on Expedia are refundable if canceled within 24-48 hours of arrival, though this depends on the hotel's individual cancellation policy, which you should check in your booking confirmation. If free cancellation is available, you can cancel directly through your Expedia account by going to "My Trips" and selecting your reservation. To find fully refundable hotel options, simply enter "Mcleod Regional Medical Center", set your travel dates, and use the "Fully refundable" filter under "Deals & Discounts" on the results page. Alternatively, explore [deals with free cancellation](https://www.expedia.ca/deals/free-cancellation) options on Expedia. ### Can I find Expedia discounts for hotels near Mcleod Regional Medical Center? > Sign in to your account to unlock instant savings and access Member Prices on Expedia. Members always get our best prices, so join for free and look for great discounts on top hotels near Mcleod Regional Medical Center. ## Explore a world of travel with Expedia - Lodging - Cars - Vacation Rental - [5 Star Hotels in Florence](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Ashland Hotels](https://www.expedia.ca/Ashland-Hotels.d553248635975868534.Travel-Guide-Hotels) - [Blenheim Hotels](https://www.expedia.ca/Blenheim-Hotels.d3000353092.Travel-Guide-Hotels) - [Hotels near Coker College](https://www.expedia.ca/Coker-College-Hotels.0-l6144920-0.Travel-Guide-Filter-Hotels) - [Coward Hotels](https://www.expedia.ca/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [B&B in Darlington](https://www.expedia.ca/Darlington-Bed-And-Breakfast.d7558-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Darlington](https://www.expedia.ca/Darlington-Guest-Houses.d7558-aaGuestHouses.Travel-Guide-Accommodation) - [Beach Hotel Hotels in Darlington](https://www.expedia.ca/Darlington-Hotels-Beach-Hotel.0-0-d7558-tBeachHotel.Travel-Guide-Filter-Hotels) - 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[Olanta Hotels](https://www.expedia.ca/Olanta-Hotels.d3000456042.Travel-Guide-Hotels) - [Pamplico Hotels](https://www.expedia.ca/Pamplico-Hotels.d3000353197.Travel-Guide-Hotels) - [Scranton Hotels](https://www.expedia.ca/Scranton-Hotels.d3000456074.Travel-Guide-Hotels) - [Aparthotels in Sellers](https://www.expedia.ca/Sellers-Apart-Hotels.d3000353228-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Sellers](https://www.expedia.ca/Sellers-Bed-And-Breakfast.d3000353228-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Sellers Hotels](https://www.expedia.ca/Sellers-Hotels.d3000353228.Travel-Guide-Hotels) - [Rv Parks in Sellers](https://www.expedia.ca/Sellers-RV-Parks.d3000353228-aaRVParks.Travel-Guide-Accommodation) - [Society Hill Hotels](https://www.expedia.ca/Society-Hill-Hotels.d553248634999443867.Travel-Guide-Hotels) - [Hotels near The Traces Golf Club](https://www.expedia.ca/The-Traces-Golf-Club-Hotels.0-l6162131-0.Travel-Guide-Filter-Hotels) - [Timmonsville Hotels](https://www.expedia.ca/Timmonsville-Hotels.d180880.Travel-Guide-Hotels) - [Turbeville Hotels](https://www.expedia.ca/Turbeville-Hotels.d167716.Travel-Guide-Hotels) - [Avis Rental Cars in Florence Regional](https://www.expedia.ca/Avis-Car-Rentals-In-Florence-Regional.d6027805-c41.Car-Rental-Guide-Suppliers) - [Car rental Darlington](https://www.expedia.ca/Car-Rentals-In-Darlington.d7558.Car-Rental-Guide) - [Rental cars Florence Regional airport](https://www.expedia.ca/Car-Rentals-In-Florence-Regional.d6027805.Car-Rental-Guide) - [Car rental Florence](https://www.expedia.ca/Car-Rentals-In-Florence.d1221.Car-Rental-Guide) - [Enterprise Rental Cars in Darlington](https://www.expedia.ca/Enterprise-Car-Rentals-In-Darlington.d7558-c15.Car-Rental-Guide-Suppliers) - [Enterprise Rental Cars in Florence Regional](https://www.expedia.ca/Enterprise-Car-Rentals-In-Florence-Regional.d6027805-c15.Car-Rental-Guide-Suppliers) - [Hertz Rental Cars in Florence Regional](https://www.expedia.ca/Hertz-Car-Rentals-In-Florence-Regional.d6027805-c40.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Florence](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Florence.d1221-c45.Car-Rental-Guide-Suppliers) - [Darlington Vacation Rentals](https://www.expedia.ca/Darlington-Vacation-Rentals.d7558.Travel-Guide-VacationRentals)