Title: The 10 Best Hotels Near Mcleod Regional Medical Center, Florence from CA $83 | Expedia.ca [Florence Travel Guide](https://expedia.ca/Florence.dx1221)[Vacation Rentals in Florence](https://expedia.ca/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Mcleod Regional Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide)[Mcleod Regional Medical Center Vacations](https://expedia.ca/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) ![Florence_McleodRegionalMedicalCenter_6162127_0006](https://images.trvl-media.com/place/6162127/fc91dc39-457a-4bce-865f-7d732cbd43f6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6162127/fc91dc39-457a-4bce-865f-7d732cbd43f6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Jan 14 - Jan 15](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-01-14&endDate=2026-01-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Jan 15 - Jan 16](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-01-15&endDate=2026-01-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Mcleod Regional Medical Center hotels ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/a93e569b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/0e00b7af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) 0.7 km from Mcleod Regional Medical Center 9.0/10 Wonderful (1,000 reviews) "Only stayed for a night, but everything was excellent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nelson CA $139 CA $156 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/e5aa7c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/91a83018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/9a944163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Florence, Tapestry Collection by Hilton [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) 0.8 km from Mcleod Regional Medical Center 9.0/10 Wonderful (613 reviews) "Special place. Great staff with an outstanding restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John D CA $181 CA $203 total includes taxes & fees Feb 5 - Feb 6 [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/00586c85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0c64863b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) 5.5 km from Mcleod Regional Medical Center 9.0/10 Wonderful (2,236 reviews) "Room was clean, staff friendly, and the includes breakfast was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha CA $117 CA $132 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/e7174d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/8a1b879d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) 5.5 km from Mcleod Regional Medical Center 8.6/10 Excellent (2,537 reviews) "Clean rooms, good breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Suman CA $98 CA $109 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a63ff680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fad493a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) 7 km from Mcleod Regional Medical Center 9.2/10 Wonderful (1,181 reviews) "Nice staff, clean, , convenient location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) kathleen CA $134 CA $150 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/a2c60bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/3e9ccd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) 5.7 km from Mcleod Regional Medical Center 9.0/10 Wonderful (838 reviews) "Room clean, breakfast excellent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robin CA $163 CA $182 total includes taxes & fees Feb 4 - Feb 5 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/7f29240e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/3c3cf86e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/867e6dd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/43e262ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Florence [](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) 5.7 km from Mcleod Regional Medical Center 8.0/10 Very good (1,679 reviews) "Extremely clean room very friendly staff breakfast had a great variety" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen Theresa CA $131 CA $147 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Studio, Multiple Beds](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/63709e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ca4e1745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) 7 km from Mcleod Regional Medical Center 9.0/10 Wonderful (727 reviews) "Clean room, staff was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $138 CA $154 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/5b7b6acc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/d5b1a48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) 5.9 km from Mcleod Regional Medical Center 8.4/10 Very good (1,002 reviews) "We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marita CA $130 CA $150 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, pillowtop beds, desk, blackout drapes](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/67a43c3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/5054dc3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) 5.9 km from Mcleod Regional Medical Center 8.4/10 Very good (1,001 reviews) "Great accommodations and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $142 CA $165 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5a5d3612.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/6cda2c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/7942388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 [](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) 6.9 km from Mcleod Regional Medical Center 9.0/10 Wonderful (573 reviews) "Wonderful stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gilad CA $152 CA $171 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/17df73d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Accessible (Communications, Mobility, Access Tub)](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/cfd93cd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/fb5956cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1509700/1509674/6c72c859.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) 8 km from Mcleod Regional Medical Center 9.2/10 Wonderful (1,000 reviews) "Clean rooms and nice breakfast. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adam CA $153 CA $171 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-Holiday-Inn-Ex-Hotel-Suites-Florence-I-95-I-20-Civic-Ctr.h1509674.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/e08b1bcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/c76a36a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/4aae214d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/7c55894f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Residence Inn Marriott Florence [](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) 7.2 km from Mcleod Regional Medical Center 8.8/10 Excellent (498 reviews) "Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marialinda CA $138 CA $154 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Suite, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/bad3cc5c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/5961e0c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/f9e4e6e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/980000/975000/974962/ad99b77d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Florence [](https://www.expedia.ca/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) 7.2 km from Mcleod Regional Medical Center 8.6/10 Excellent (990 reviews) "The room was clean and spacious and the check-in was very easy. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $141 CA $158 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-SpringHill-Suites-By-Marriott-Florence.h974962.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/1a4a47d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/d6de6ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/dab62d55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) 5.9 km from Mcleod Regional Medical Center 6.8/10 (1,000 reviews) "Great" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Cleveland CA $77 CA $86 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/88f4ba4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/ee878326.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) 7.2 km from Mcleod Regional Medical Center 9.0/10 Wonderful (836 reviews) "My go to stay while in Fairfax. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Gregory CA $147 CA $165 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/25cb76ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/bdaaa724.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/2132b0fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/41091644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Florence North I-95, SC [](https://www.expedia.ca/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) 5.5 km from Mcleod Regional Medical Center 7.8/10 Good (39 reviews) "The front desk representative was very friendly. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elaine CA $131 CA $152 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/6ea04fee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Suite | Private kitchen](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/bca415cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/b658ab38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/58000000/57720000/57719800/57719723/d32e89e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Affordable Suites Florence [](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) 7 km from Mcleod Regional Medical Center 9.2/10 Wonderful (129 reviews) "Nice clean room; friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angelo [](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/1000000/10000/500/455/ef1db617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn [](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) 4.7 km from Mcleod Regional Medical Center 7.8/10 Good (1,002 reviews) "Good clean room and staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Akshay Navinchandra CA $124 CA $138 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/2d26ec35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/73965d7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence [](https://www.expedia.ca/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) 6.1 km from Mcleod Regional Medical Center 6.8/10 (1,001 reviews) "Friendly staff, clean rooms, nice location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sheila CA $74 CA $83 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-29&endDate=2026-01-30®ionId=6162127&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Top Mcleod Regional Medical Center Hotel Reviews ![TownePlace Suites by Marriott Florence](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6_y.jpg) ### TownePlace Suites by Marriott Florence 10/10 Excellent "Very clean & neat room, reg size refrigerator & grill areas nice, the shower had oroblem with achieving full water spray (half was coming out of tub faucet), water only lukewarm" [](https://expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "No dinner options" [](https://expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/80000/74500/74404/484ca695_y.jpg) ### La Quinta Inn & Suites by Wyndham Florence 10/10 Excellent "Extremely clean room very friendly staff breakfast had a great variety" [](https://expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "Variety of things to eat in the breakfast menu. Plenty of space to park my vehicle " [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg) ### Hampton Inn & Suites Florence Center 10/10 Excellent "Staff great. clean room." [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Tru by Hilton Florence I-95](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d_y.jpg) ### Tru by Hilton Florence I-95 10/10 Excellent "Check in was fast and easy. Staff was very friendly and attentive. Place was very clean. Room was very clean and comfortable." [](https://expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "not a lot to choose from for breakfast. AC was fine in the room." [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hotel Florence, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8_y.jpg) ### Hotel Florence, Tapestry Collection by Hilton 10/10 Excellent "Yes" [](https://expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "One of the cleanest places we’ve ever stayed and the nicest, most helpful staff. Highly recommend!" [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ## Hotels near other Mcleod Regional Medical Center attractions ![Florence_FlorenceMuseum_6162137_0005](https://images.trvl-media.com/place/6162137/dd0f8253-2cfa-4203-89de-823ddac9605e.jpg) ### Florence Museum 3.8/5 (122 reviews) You can spend time browsing the exhibits at Florence Museum in Florence. While in this trendy area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6162137) ![Florence_MagnoliaMall_6165602_0005](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg) ### Magnolia Mall 4.0/5 (410 reviews) You can enjoy retail therapy at Magnolia Mall during your visit to Florence. While in this trendy area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6165602) ### Drs Bruce and Lee Foundation Library Learn about the local history of Florence when you spend time at Drs Bruce and Lee Foundation Library. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950929591644532736) ### War Between the States Museum You can spend an afternoon exploring the galleries in War Between the States Museum during your travels in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950930659214794752) ### Dr. Eddie Floyd Tennis Center Catch an event at Dr. Eddie Floyd Tennis Center during your trip to Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624453535023104) ### South Park South Park is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911207011182792704) ### Old Greenwood Athletic Park After visiting Old Greenwood Athletic Park, make a plan to see the other sights and activities in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911210743347908608) ### Florence Veterans Park Explore the great outdoors at Florence Veterans Park, a lovely green space in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=619470572411232256) ## Frequently asked questions ### What are the top-rated hotels near Mcleod Regional Medical Center? > [Affordable Suites Florence](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) > > > Affordable Suites Florence is a welcoming choice for travellers, located just 7.4 km from Mcleod Regional Medical Center and an impressive review rating of 9.4\. This hotel features essential amenities such as air conditioning for comfort and self-parking options, including free uncovered parking. Guests appreciate the accessibility features, making it a convenient option for all travellers. > > > [Comfort Inn & Suites](https://expedia.ca/Florence-hotels-Comfort-Inn-&-Suites.h38336321.Hotel-information) > > > Comfort Inn & Suites offers a comfortable stay just 7.9 km from Mcleod Regional Medical Center, rated 9.2 by travellers. This hotel is well-equipped with amenities like a 24-hour fitness centre and a refreshing accessible pool. Guests can start their day with a complimentary daily breakfast, including continental options, and enjoy the convenience of a microwave in their rooms. The inviting atmosphere and thoughtful amenities make it a great choice for those visiting the area. > > > [TownePlace Suites by Marriott Florence](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) > > > TownePlace Suites by Marriott Florence presents a delightful experience with a review rating of 9.0 and a solid 3-star rating, located 7.7 km from Mcleod Regional Medical Center. This hotel stands out with its spacious suites featuring kitchens equipped with stovetops, refrigerators, and dishwashers, ideal for longer stays. Guests can unwind at the outdoor pool or enjoy a complimentary buffet breakfast each morning. The rooftop garden adds a unique touch, offering a serene space for relaxation. ### What hotels are within walking distance to Mcleod Regional Medical Center? > [Hotel Florence, Tapestry Collection by Hilton](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) > > > Hotel Florence, Tapestry Collection by Hilton is a charming 3-star hotel located just a 6-minute walk from Mcleod Regional Medical Center. With a review rating of 8.8, this hotel offers travellers a range of luxurious amenities including a full-service spa featuring massage treatments, aromatherapy, and a fitness centre open 24 hours. Guests can indulge in various body treatments or relax in bathrobes with designer toiletries provided. The historical district location adds a unique touch to the stay, making it an inviting choice for travellers looking for relaxation and convenience. > > > [Hyatt Place Florence Downtown](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) > > > Hyatt Place Florence Downtown is a modern 3-star hotel situated just 7 minutes away on foot from Mcleod Regional Medical Center. Rated 8.8 by travellers, this hotel features a refreshing outdoor pool and a fitness centre available around the clock. Guests can enjoy a complimentary breakfast daily, including options for weekends, as well as a 24-hour restaurant. The comfortable rooms, equipped with sofa beds, ensure a cozy stay, making it a practical choice for those visiting the area. ### How much is a hotel near Mcleod Regional Medical Center? ### What are the most popular family-friendly hotels near Mcleod Regional Medical Center? > [Aloft Florence](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) > > > Aloft Florence is a delightful 3-star hotel located just 7.9 km from Mcleod Regional Medical Center, with a strong travellers' rating of 8.4\. This family-friendly hotel offers amenities like an indoor pool, free cribs, and connecting rooms, ensuring a comfortable stay for travellers of all ages. Kids will enjoy the arcade game room, while parents will appreciate the daily housekeeping and fitness facilities available 24 hours. > > > [Comfort Suites Florence I-95](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) > > > Comfort Suites Florence I-95, located 6.6 km from Mcleod Regional Medical Center, boasts a solid review rating of 8.4\. This family-friendly hotel features accessible indoor pool facilities and complimentary breakfast, making it easy to start the day right. Guests can take advantage of connecting rooms and in-room microwaves, ensuring a convenient and enjoyable stay for families. > > > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > Best Western Inn is a welcoming option just 5.0 km from Mcleod Regional Medical Center, rated by travellers at 7.6\. Families will appreciate the accessibility of the pool and the availability of free cribs and connecting rooms. With a complimentary continental breakfast and a secured pool area, this hotel is designed to cater to the needs of families looking for a comfortable stay. ### Are there any hotels with pools close to Mcleod Regional Medical Center? > [Aloft Florence](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) > > > Aloft Florence is situated 7.9 km from Mcleod Regional Medical Center and boasts an impressive review rating of 8.4\. This 3-star hotel features a 24-hour indoor pool accessible to all travellers. Additional offerings include a fitness centre, arcade game room, and complimentary amenities for children, creating a fun and engaging environment for families. > > > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > Located only 5.0 km from Mcleod Regional Medical Center, Best Western Inn provides a welcoming atmosphere with a shared outdoor pool, rated by travellers at 7.6\. This hotel offers accessible pool facilities along with complimentary breakfast and free self-parking, ensuring convenience for all travellers. Its comfortable accommodations and amenities like cribs and premium bedding make it a great choice for families. > > > [Residence Inn Marriott Florence](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) > > > Just 7.7 km from Mcleod Regional Medical Center, the 3-star Residence Inn Marriott Florence offers a delightful outdoor pool experience for travellers. With a great traveler rating score of 8.8, this hotel features sun loungers, umbrellas, and a gated pool area, ensuring a relaxing environment. Additional amenities include free breakfast, a hot tub, and spacious suites with kitchens, making it ideal for families and extended stays. ### What are the best pet-friendly hotels near Mcleod Regional Medical Center? > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > Best Western Inn is situated only 5.0 km from Mcleod Regional Medical Center and features a favorable traveler rating of 7.6\. This pet-friendly hotel welcomes dogs and cats, making it a comfortable choice for travellers with pets. Guests can indulge in free breakfast, enjoy the outdoor pool, and take advantage of the early check-in and late check-out options, ensuring a pleasant stay for both you and your furry companions. > > > [La Quinta Inn & Suites by Wyndham Florence](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) > > > La Quinta Inn & Suites by Wyndham Florence is a welcoming 3-star hotel located just 5.8 km from Mcleod Regional Medical Center. Rated by travellers with a solid 8.0, this hotel is ideal for pet owners, offering pet-friendly amenities including in-room pet access and designated areas for pets. Guests can enjoy a range of conveniences such as free breakfast, a fitness centre, and an outdoor pool, making it a great choice for families and those needing a relaxing getaway. > > > [Red Roof Inn Florence - Civic Center](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) > > > Red Roof Inn Florence - Civic Center is located 7.2 km from Mcleod Regional Medical Center, with a review rating of 6.8\. This budget-friendly hotel is pet-friendly, allowing pets in rooms, and is perfect for travellers traveling with their four-legged pals. The hotel features essential amenities like a kitchenette, free toiletries, and convenient self-parking, making it a practical choice for those seeking affordability and comfort. ### Can I book a fully refundable hotel close to Mcleod Regional Medical Center? ### Can I find Expedia discounts for hotels near Mcleod Regional Medical Center? ## Explore a world of travel with Expedia - Lodging - Flights - Cars - Vacation Rental - [5 Star Hotels in Florence ](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Ashland Hotels ](https://www.expedia.ca/Ashland-Hotels.d553248635975868534.Travel-Guide-Hotels) - [Blenheim Hotels ](https://www.expedia.ca/Blenheim-Hotels.d3000353092.Travel-Guide-Hotels) - [Hotels near Coker College ](https://www.expedia.ca/Coker-College-Hotels.0-l6144920-0.Travel-Guide-Filter-Hotels) - [Coward Hotels ](https://www.expedia.ca/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [B&B in Darlington ](https://www.expedia.ca/Darlington-Bed-And-Breakfast.d7558-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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