Title: The 10 Best Hotels Near Mcleod Regional Medical Center, Florence from CA $66 | Expedia.ca [Florence Travel Guide](https://expedia.ca/Florence.dx1221)[Vacation Rentals in Florence](https://expedia.ca/Florence-Vacation-Rentals.d1221.Travel-Guide-VacationRentals)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1221.Travel-Guide-Flights)[Mcleod Regional Medical Center Car Rentals](https://expedia.ca/Car-Rentals-In-Mcleod-Regional-Medical-Center.d6162127.Car-Rental-Guide)[Mcleod Regional Medical Center Vacations](https://expedia.ca/Mcleod-Regional-Medical-Center-Florence.d6162127.Vacation-Attraction) ![Florence_McleodRegionalMedicalCenter_6162127_0006](https://images.trvl-media.com/place/6162127/fc91dc39-457a-4bce-865f-7d732cbd43f6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6162127/fc91dc39-457a-4bce-865f-7d732cbd43f6.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 1 - Mar 2](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-03-01&endDate=2026-03-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 2 - Mar 3](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=6162127&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Our top choices for Mcleod Regional Medical Center hotels ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Serves lunch and dinner](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/e2ea309a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/a93e569b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Florence Downtown [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) 0.7 km from Mcleod Regional Medical Center 9.0/10 Wonderful (1,000 reviews) "Great location and well maintained property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen CA $160 CA $179 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/e5aa7c6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/05b9e041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/91a83018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Florence, Tapestry Collection by Hilton [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) 0.8 km from Mcleod Regional Medical Center 8.8/10 Excellent (620 reviews) "Special place. Great staff with an outstanding restaurant " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John D CA $179 CA $200 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/119000000/118990000/118982900/118982850/8e3233ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rodeway Inn Florence Downtown [](https://www.expedia.ca/Florence-Hotels-Rodeway-Inn.h118982850.Hotel-Information) 1.2 km from Mcleod Regional Medical Center 6.0/10 (2 reviews) "Good" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joshua CA $67 CA $77 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Florence-Hotels-Rodeway-Inn.h118982850.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0b9239a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/0c64863b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Park Inn by Radisson Florence, SC [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) 5.5 km from Mcleod Regional Medical Center 9.0/10 Wonderful (2,241 reviews) "Room was clean, staff friendly, and the includes breakfast was great " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Samantha CA $117 CA $131 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/3ba2ede7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/d6de6ad6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/1a4a47d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Florence/I-95 North [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) 5.9 km from Mcleod Regional Medical Center 6.8/10 (1,002 reviews) "Great room and reasonable price " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hattab CA $87 CA $98 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Room, 1 Queen Bed, Accessible, Non Smoking](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/4d56e96c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/cbd95825.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/93db4fd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/200000/200000/199996/2d26ec35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Microtel Inn & Suites by Wyndham Florence [](https://www.expedia.ca/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) 6.1 km from Mcleod Regional Medical Center 6.8/10 (1,002 reviews) "Friendly staff, clean room, very comfortable bed " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Willie CA $86 CA $96 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Florence-Hotels-Microtel-Inn-Suites-By-Wyndham-Florence.h199996.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/995e3ecd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/36a85f8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/3e9ccd76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/3000000/2400000/2393000/2392993/59604fe9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence-North-I-95 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) 5.7 km from Mcleod Regional Medical Center 9.0/10 Wonderful (871 reviews) "The employees were so nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ron CA $161 CA $180 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-North-I-95.h2392993.Hotel-Information) ![Desk, laptop workspace, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/868ff462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/f14e88ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/6673044c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/10000/2400/2337/8d075bfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Florence - Civic Center [](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) 7.2 km from Mcleod Regional Medical Center 6.8/10 (1,003 reviews) "Room was good. No microwave tho. Staff was very courteous and helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $76 CA $86 total includes taxes & fees Mar 4 - Mar 5 [](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/7b1066c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/e7174d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking (1st Floor) | Room amenity](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/f9691b25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Florence [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) 5.5 km from Mcleod Regional Medical Center 8.6/10 Excellent (2,574 reviews) "I nice place to stay, very quiet, good breakfast, nice staff, spotless room. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy CA $96 CA $107 total includes taxes & fees Mar 5 - Mar 6 [](https://www.expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/77d2b021.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/9a99b1eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/25fbc38c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, towels](https://images.trvl-media.com/lodging/1000000/900000/899000/898902/7fa5ab06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Florence, SC [](https://www.expedia.ca/Florence-Hotels-Motel-6-Florence.h898902.Hotel-Information) 5.3 km from Mcleod Regional Medical Center 6.4/10 (660 reviews) "it a good hotel it's a good hotel good people and manager is a good person" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Travis [](https://www.expedia.ca/Florence-Hotels-Motel-6-Florence.h898902.Hotel-Information) ![View from property](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/5dc20640.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/7942388a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/86912dec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/18000000/17040000/17036000/17035960/6cda2c89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Florence I-20 [](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) 6.9 km from Mcleod Regional Medical Center 9.2/10 Wonderful (590 reviews) "Friendly staff, clean and comfortable room " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) craig CA $155 CA $174 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Florence-Hotels-Fairfield-Inn-Suites-By-Marriott-Florence-I-20.h17035960.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/64840011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/6df606aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/fefdad76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a63ff680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Florence Center Area [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) 7 km from Mcleod Regional Medical Center 9.2/10 Wonderful (1,226 reviews) "The staff was friendly and the room was clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Camila CA $133 CA $149 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Premium bedding, pillowtop beds, laptop workspace, soundproofing](https://images.trvl-media.com/lodging/1000000/10000/500/455/ef1db617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/10000/500/455/be7cdd34.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 10:00 AM to 8:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/500/455/5074ad24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/500/455/af3985b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Inn [](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) 4.7 km from Mcleod Regional Medical Center 7.8/10 Good (1,002 reviews) "Front desk staff was great and very friendly! Made for a smooth check-in!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Patric CA $135 CA $151 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/c68ab7f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/434898b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/d963a865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/4000000/3030000/3026100/3026100/5054dc3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Florence I-95 [](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) 5.9 km from Mcleod Regional Medical Center 8.4/10 Very good (1,003 reviews) "Great accommodations and courteous staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Leslie CA $139 CA $162 total includes taxes & fees Mar 9 - Mar 10 [](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/a8854f5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/20f68e84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/8339db76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/28000000/27050000/27041900/27041849/d5b1a48f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tru by Hilton Florence I-95 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) 5.9 km from Mcleod Regional Medical Center 8.4/10 Very good (1,003 reviews) "We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marita CA $133 CA $154 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Florence-Hotels-Tru-By-Hilton-Florence-I-95.h27041849.Hotel-Information) ![Studio, Multiple Beds](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/cd925f1d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/4140d9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/63709e2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/11000000/10630000/10620800/10620701/ca4e1745.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TownePlace Suites by Marriott Florence [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) 7 km from Mcleod Regional Medical Center 9.0/10 Wonderful (763 reviews) "Checking in was a breeze and the staff was excellent. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany CA $144 CA $161 total includes taxes & fees Mar 15 - Mar 16 [](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) ![Check-in/check-out kiosk](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/2aa0d516.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/fb249555.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Honeymoon Single Room (327503716)](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/d9531705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/30000/20300/20253/4a7dfdb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Florence Inn and Suites [](https://www.expedia.ca/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information) 11.2 km from Mcleod Regional Medical Center 6.4/10 (333 reviews) "Parking was good " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $58 CA $66 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Florence-Hotels-Florence-Inn-And-Suites.h20253.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/88f4ba4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/f287bfc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/1e0c4eb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Florence Center [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) 7.2 km from Mcleod Regional Medical Center 9.0/10 Wonderful (857 reviews) "Staff was very kind and conscious of our needs" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Robert CA $151 CA $169 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/25cb76ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/bdaaa724.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/41091644.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42700/42602/c42cf41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spark by Hilton Florence North I-95, SC [](https://www.expedia.ca/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) 5.5 km from Mcleod Regional Medical Center 8.0/10 Very good (50 reviews) "Wonderful staff and very clean room and facilities , " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) catherine CA $162 CA $187 total includes taxes & fees Mar 2 - Mar 3 [](https://www.expedia.ca/Florence-Hotels-Spark-By-Hilton-Florence-North-I-95.h42602.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/89338f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/1aa3f791.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, Tempur-Pedic beds, in-room safe, desk](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/861e9f4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/22000000/21760000/21758600/21758593/042032ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Staybridge Suites Florence - Civic Center by IHG [](https://www.expedia.ca/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) 8.1 km from Mcleod Regional Medical Center 9.4/10 Exceptional (960 reviews) "Room clean, bed good, breakfast good choices, front desk excellent" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) mona CA $184 CA $206 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Florence-Hotels-Staybridge-Suites-Florence-Civic-Center.h21758593.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-15&endDate=2026-03-16®ionId=6162127&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Compare popular hotels close to Mcleod Regional Medical Center | Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | | | --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | ----------------- | ------------------------- | ------------------ | ---- | --- | ------------ | ------------- | | | ![Terrace/patio](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c8bc9166.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hyatt Place Florence Downtown | 3.0 star property | 9.0Wonderful1,000 reviews | View | | | | | | | ![Bar (on property)](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/e5aa7c6c.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hotel Florence, Tapestry Collection by Hilton | 3.0 star property | 8.8Excellent620 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/119000000/118990000/118982900/118982850/8e3233ca.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Rodeway Inn Florence Downtown | 2.0 star property | 6.02 reviews | View | | | | | | | ![Lobby](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/e4f3361f.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Park Inn by Radisson Florence, SC | 2.5 star property | 9.0Wonderful2,241 reviews | View | | | | | | | ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/099eb7f9.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Days Inn by Wyndham Florence/I-95 North | 2.0 star property | 6.81,002 reviews | View | | | | | | ## Top Mcleod Regional Medical Center Hotel Reviews ![Best Western Inn](https://images.trvl-media.com/lodging/1000000/10000/500/455/344e3fdf_y.jpg) ### Best Western Inn 10/10 Excellent "Room spotless, clean rooms, awesome staff, and quietness" [](https://expedia.ca/Florence-Hotels-Best-Western-Inn.h455.Hotel-Information) ![Park Inn by Radisson Florence, SC](https://images.trvl-media.com/lodging/48000000/47090000/47086800/47086732/96d5feb4_y.jpg) ### Park Inn by Radisson Florence, SC 10/10 Excellent "The rooms were clean and it’s so nice having breakfast included with our stay!" [](https://expedia.ca/Florence-Hotels-Park-Inn-By-Radisson-Florence.h47086732.Hotel-Information) ![Howard Johnson by Wyndham Florence](https://images.trvl-media.com/lodging/1000000/20000/11100/11037/32fd6fc1_y.jpg) ### Howard Johnson by Wyndham Florence 10/10 Excellent "room was clean. Staff was helpful" [](https://expedia.ca/Florence-Hotels-Howard-Johnson-By-Wyndham-Florence.h11037.Hotel-Information) ![Comfort Inn & Suites Florence Center Area](https://images.trvl-media.com/lodging/39000000/38340000/38336400/38336321/a0861bce_y.jpg) ### Comfort Inn & Suites Florence Center Area 10/10 Excellent "Clean room, and friendly staff!" [](https://expedia.ca/Florence-Hotels-Comfort-Inn-Suites.h38336321.Hotel-Information) ![Hyatt Place Florence Downtown](https://images.trvl-media.com/lodging/33000000/32780000/32772900/32772870/c29c3321_y.jpg) ### Hyatt Place Florence Downtown 10/10 Excellent "Great rooms" [](https://expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) ![Days Inn by Wyndham Florence/I-95 North](https://images.trvl-media.com/lodging/1000000/20000/15500/15497/b1bbd639_y.jpg) ### Days Inn by Wyndham Florence/I-95 North 10/10 Excellent "Staff and room" [](https://expedia.ca/Florence-Hotels-Days-Inn-By-Wyndham-FlorenceI-95-North.h15497.Hotel-Information) ![Hotel Florence, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/7000000/6130000/6129000/6128999/af0558b8_y.jpg) ### Hotel Florence, Tapestry Collection by Hilton 10/10 Excellent "Nice room. Good breakfast. Interesting town" [](https://expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) ![Residence Inn Marriott Florence](https://images.trvl-media.com/lodging/3000000/2480000/2478700/2478624/a45dedcb_y.jpg) ### Residence Inn Marriott Florence 10/10 Excellent "Room was clean and Ms. Angel at the front desk got me checked in quickly. The true queen on staff was MS. Cynthia she made breakfast feel like you were eating at your Aunties house. Will definitely be back next year!!!" [](https://expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) ![Hampton Inn & Suites Florence Center](https://images.trvl-media.com/lodging/1000000/50000/42900/42876/e1b59003_y.jpg) ### Hampton Inn & Suites Florence Center 10/10 Excellent "Staff was amazing, and rooms where so nice!" [](https://expedia.ca/Florence-Hotels-Hampton-Inn-Suites-Florence-Center.h42876.Hotel-Information) ## Hotels near other Mcleod Regional Medical Center attractions ![Florence_FlorenceMuseum_6162137_0005](https://images.trvl-media.com/place/6162137/dd0f8253-2cfa-4203-89de-823ddac9605e.jpg) ### Florence Museum 3.8/5 (122 reviews) You can spend time browsing the exhibits at Florence Museum in Florence. While in this relaxing area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6162137) ![Florence_MagnoliaMall_6165602_0005](https://images.trvl-media.com/place/6165602/4392990f-7038-4d9a-a654-83ae3a3dcd0f.jpg) ### Magnolia Mall 4.0/5 (410 reviews) You can enjoy retail therapy at Magnolia Mall during your visit to Florence. While in this family-friendly area, you can savor the top-notch restaurants. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6165602) ### Drs Bruce and Lee Foundation Library Learn about the local history of Florence when you spend time at Drs Bruce and Lee Foundation Library. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950929591644532736) ### War Between the States Museum You can spend an afternoon exploring the galleries in War Between the States Museum during your travels in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=950930659214794752) ### Dr. Eddie Floyd Tennis Center Catch an event at Dr. Eddie Floyd Tennis Center during your trip to Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=941624453535023104) ### South Park South Park is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911207011182792704) ### Old Greenwood Athletic Park After visiting Old Greenwood Athletic Park, make a plan to see the other sights and activities in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=911210743347908608) ### Florence Veterans Park Explore the great outdoors at Florence Veterans Park, a lovely green space in Florence. Check out the shops and top-notch restaurants in this family-friendly area. [See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=619470572411232256) ## Frequently asked questions ### What are the top-rated hotels near Mcleod Regional Medical Center? > [Affordable Suites Florence](https://www.expedia.ca/Florence-Hotels-Affordable-Suites-Florence.h57719723.Hotel-Information) > > > Affordable Suites Florence is a welcoming choice for travellers, located just 7.4 km from Mcleod Regional Medical Center and an impressive review rating of 9.4\. This hotel features essential amenities such as air conditioning for comfort and self-parking options, including free uncovered parking. Guests appreciate the accessibility features, making it a convenient option for all travellers. > > > [Comfort Inn & Suites](https://expedia.ca/Florence-hotels-Comfort-Inn-&-Suites.h38336321.Hotel-information) > > > Comfort Inn & Suites offers a comfortable stay just 7.9 km from Mcleod Regional Medical Center, rated 9.2 by travellers. This hotel is well-equipped with amenities like a 24-hour fitness centre and a refreshing accessible pool. Guests can start their day with a complimentary daily breakfast, including continental options, and enjoy the convenience of a microwave in their rooms. The inviting atmosphere and thoughtful amenities make it a great choice for those visiting the area. > > > [TownePlace Suites by Marriott Florence](https://www.expedia.ca/Florence-Hotels-TownePlace-Suites-By-Marriott-Florence.h10620701.Hotel-Information) > > > TownePlace Suites by Marriott Florence presents a delightful experience with a review rating of 9.0 and a solid 3-star rating, located 7.7 km from Mcleod Regional Medical Center. This hotel stands out with its spacious suites featuring kitchens equipped with stovetops, refrigerators, and dishwashers, ideal for longer stays. Guests can unwind at the outdoor pool or enjoy a complimentary buffet breakfast each morning. The rooftop garden adds a unique touch, offering a serene space for relaxation. ### What hotels are within walking distance to Mcleod Regional Medical Center? > [Hotel Florence, Tapestry Collection by Hilton](https://www.expedia.ca/Florence-Hotels-Hotel-Florence.h6128999.Hotel-Information) > > > Hotel Florence, Tapestry Collection by Hilton is a charming 3-star hotel located just a 6-minute walk from Mcleod Regional Medical Center. With a review rating of 8.8, this hotel offers travellers a range of luxurious amenities including a full-service spa featuring massage treatments, aromatherapy, and a fitness centre open 24 hours. Guests can indulge in various body treatments or relax in bathrobes with designer toiletries provided. The historical district location adds a unique touch to the stay, making it an inviting choice for travellers looking for relaxation and convenience. > > > [Hyatt Place Florence Downtown](https://www.expedia.ca/Florence-Hotels-Hyatt-Place-Florence-Downtown.h32772870.Hotel-Information) > > > Hyatt Place Florence Downtown is a modern 3-star hotel situated just 7 minutes away on foot from Mcleod Regional Medical Center. Rated 8.8 by travellers, this hotel features a refreshing outdoor pool and a fitness centre available around the clock. Guests can enjoy a complimentary breakfast daily, including options for weekends, as well as a 24-hour restaurant. The comfortable rooms, equipped with sofa beds, ensure a cozy stay, making it a practical choice for those visiting the area. ### How much is a hotel near Mcleod Regional Medical Center? ### What are the most popular family-friendly hotels near Mcleod Regional Medical Center? > [Aloft Florence](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) > > > Aloft Florence is a delightful 3-star hotel located just 7.9 km from Mcleod Regional Medical Center, with a strong travellers' rating of 8.4\. This family-friendly hotel offers amenities like an indoor pool, free cribs, and connecting rooms, ensuring a comfortable stay for travellers of all ages. Kids will enjoy the arcade game room, while parents will appreciate the daily housekeeping and fitness facilities available 24 hours. > > > [Comfort Suites Florence I-95](https://www.expedia.ca/Florence-Hotels-Comfort-Suites-Florence-I-95.h3026100.Hotel-Information) > > > Comfort Suites Florence I-95, located 6.6 km from Mcleod Regional Medical Center, boasts a solid review rating of 8.4\. This family-friendly hotel features accessible indoor pool facilities and complimentary breakfast, making it easy to start the day right. Guests can take advantage of connecting rooms and in-room microwaves, ensuring a convenient and enjoyable stay for families. > > > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > Best Western Inn is a welcoming option just 5.0 km from Mcleod Regional Medical Center, rated by travellers at 7.6\. Families will appreciate the accessibility of the pool and the availability of free cribs and connecting rooms. With a complimentary continental breakfast and a secured pool area, this hotel is designed to cater to the needs of families looking for a comfortable stay. ### Are there any hotels with pools close to Mcleod Regional Medical Center? > [Aloft Florence](https://www.expedia.ca/Florence-Hotels-Aloft-Florence.h76026194.Hotel-Information) > > > Aloft Florence is situated 7.9 km from Mcleod Regional Medical Center and boasts an impressive review rating of 8.4\. This 3-star hotel features a 24-hour indoor pool accessible to all travellers. Additional offerings include a fitness centre, arcade game room, and complimentary amenities for children, creating a fun and engaging environment for families. > > > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > Located only 5.0 km from Mcleod Regional Medical Center, Best Western Inn provides a welcoming atmosphere with a shared outdoor pool, rated by travellers at 7.6\. This hotel offers accessible pool facilities along with complimentary breakfast and free self-parking, ensuring convenience for all travellers. Its comfortable accommodations and amenities like cribs and premium bedding make it a great choice for families. > > > [Residence Inn Marriott Florence](https://www.expedia.ca/Florence-Hotels-Residence-Inn-Marriott-Florence.h2478624.Hotel-Information) > > > Just 7.7 km from Mcleod Regional Medical Center, the 3-star Residence Inn Marriott Florence offers a delightful outdoor pool experience for travellers. With a great traveler rating score of 8.8, this hotel features sun loungers, umbrellas, and a gated pool area, ensuring a relaxing environment. Additional amenities include free breakfast, a hot tub, and spacious suites with kitchens, making it ideal for families and extended stays. ### What are the best pet-friendly hotels near Mcleod Regional Medical Center? > [Best Western Inn](https://expedia.ca/Florence-hotels-Best-Western-Inn.h455.Hotel-information) > > > Best Western Inn is situated only 5.0 km from Mcleod Regional Medical Center and features a favorable traveler rating of 7.6\. This pet-friendly hotel welcomes dogs and cats, making it a comfortable choice for travellers with pets. Guests can indulge in free breakfast, enjoy the outdoor pool, and take advantage of the early check-in and late check-out options, ensuring a pleasant stay for both you and your furry companions. > > > [La Quinta Inn & Suites by Wyndham Florence](https://www.expedia.ca/Florence-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Florence.h74404.Hotel-Information) > > > La Quinta Inn & Suites by Wyndham Florence is a welcoming 3-star hotel located just 5.8 km from Mcleod Regional Medical Center. Rated by travellers with a solid 8.0, this hotel is ideal for pet owners, offering pet-friendly amenities including in-room pet access and designated areas for pets. Guests can enjoy a range of conveniences such as free breakfast, a fitness centre, and an outdoor pool, making it a great choice for families and those needing a relaxing getaway. > > > [Red Roof Inn Florence - Civic Center](https://www.expedia.ca/Florence-Hotels-Red-Roof-Inn-Florence-Civic-Center.h2337.Hotel-Information) > > > Red Roof Inn Florence - Civic Center is located 7.2 km from Mcleod Regional Medical Center, with a review rating of 6.8\. This budget-friendly hotel is pet-friendly, allowing pets in rooms, and is perfect for travellers traveling with their four-legged pals. The hotel features essential amenities like a kitchenette, free toiletries, and convenient self-parking, making it a practical choice for those seeking affordability and comfort. ### Can I book a fully refundable hotel close to Mcleod Regional Medical Center? ### Can I find Expedia discounts for hotels near Mcleod Regional Medical Center? ## Explore a world of travel with Expedia - Lodging - Flights - Cars - Vacation Rental - [5 Star Hotels in Florence ](https://www.expedia.ca/5Star-Florence-Hotels.s50-0-d1221.Travel-Guide-Filter-Hotels) - [Ashland Hotels ](https://www.expedia.ca/Ashland-Hotels.d553248635975868534.Travel-Guide-Hotels) - [Blenheim Hotels ](https://www.expedia.ca/Blenheim-Hotels.d3000353092.Travel-Guide-Hotels) - [Hotels near Coker College ](https://www.expedia.ca/Coker-College-Hotels.0-l6144920-0.Travel-Guide-Filter-Hotels) - [Coward Hotels ](https://www.expedia.ca/Coward-Hotels.d3000353109.Travel-Guide-Hotels) - [B&B in Darlington ](https://www.expedia.ca/Darlington-Bed-And-Breakfast.d7558-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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