Florence Vacation Rentals

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Our top choices for Florence vacation rentals

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views
Hartsville
10.0 out of 10, Exceptional, (8 reviews)
"Sooo good. Peaceful country setting yet close to everything. We will definitely try staying here again next time."
United States
Randy W.
The price is CA $98
CA $212 total
includes taxes & fees
Feb 9 - Feb 10
Charming 2-bedroom apartment MINUTES from Darlington Raceway with pond views

Cozy Blue Cottage 2BR/1BA

Cozy Blue Cottage 2BR/1BA
Hartsville
9.0 out of 10, Wonderful, (8 reviews)
"Enjoyed my time in Hartsville with family "
United States
Lori
The price is CA $150
CA $322 total
includes taxes & fees
Feb 9 - Feb 10
Cozy Blue Cottage 2BR/1BA

Charming Cottage with easy access to local attractions-pet and kid friendly

Charming Cottage with easy access to local attractions-pet and kid friendly
Sellers
9.6 out of 10, Exceptional, (21 reviews)
"So charming. The hostess is very accommodating and willing. We felt very welcome. All the accoutrements are tasteful. We had plenty of what we needed for our little celebration. Not too far of a skirt to Flo-town for a bite and some dessert. "
United States
Benjamin
The price is CA $129
CA $269 total
includes taxes & fees
Feb 9 - Feb 10
Charming Cottage with easy access to local attractions-pet and kid friendly

imperial motel

imperial motel
Mullins
The price is CA $123
CA $176 total
includes taxes & fees
Feb 9 - Feb 10
imperial motel

In 1840 Burn Cottage

In 1840 Burn Cottage
Society Hill
9.6 out of 10, Exceptional, (34 reviews)
"Nice historic house provided authentic late-1800s three night stay. Enjoyed our stay."
United States
Ansel C.
The price is CA $148
CA $283 total
includes taxes & fees
Feb 9 - Feb 10
In 1840 Burn Cottage

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
Hartsville
8.0 out of 10, Very good, (1 review)
"The stay was fine , with no problems."
United States
Mark H.
The price is CA $92
CA $205 total
includes taxes & fees
Feb 15 - Feb 16
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi

Private Pool house in Mullins

Private Pool house in Mullins
Mullins
9.2 out of 10, Wonderful, (7 reviews)
"Great stay in Mullins. We enjoyed family time at the pool and had everything we needed. "
United States
Carla H.
The price is CA $137
CA $256 total
includes taxes & fees
Feb 9 - Feb 10
Private Pool house in Mullins

Walking distance from one of South Carolina's top Medical centers.

Walking distance from one of South Carolina's top Medical centers.
Florence
9.8 out of 10, Exceptional, (42 reviews)
"The house was beautiful. We would stay there again!!"
United States
Stephanie L.
The price is CA $183
CA $319 total
includes taxes & fees
Feb 9 - Feb 10
Walking distance from one of South Carolina's top Medical centers.

Peaceful Farm Getaway

Peaceful Farm Getaway
Mullins
10.0 out of 10, Exceptional, (32 reviews)
"Excellent Space. Loved It."
United States
Rodney
The price is CA $185
CA $288 total
includes taxes & fees
Feb 9 - Feb 10
Peaceful Farm Getaway

Lovely upscale 3-bedroom Loft apartment downtown Marion

Lovely upscale 3-bedroom Loft apartment downtown Marion
Marion
The price is CA $246
CA $304 total
includes taxes & fees
Feb 9 - Feb 10
Lovely upscale 3-bedroom Loft apartment downtown Marion

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
Florence
8.8 out of 10, Excellent, (3 reviews)
"Convenient location"
United States
Bonney W.
The price is CA $166
CA $644 total
includes taxes & fees
Feb 9 - Feb 10
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.

The Pinecone Retreat - Only 1 mile from i95

The Pinecone Retreat - Only 1 mile from i95
Latta
The price is CA $142
CA $185 total
includes taxes & fees
Feb 15 - Feb 16
The Pinecone Retreat - Only 1 mile from i95

Secret SC Cabin on 100 acres Hot Tub Large Pond

Secret SC Cabin on 100 acres Hot Tub Large Pond
Marion
9.6 out of 10, Exceptional, (180 reviews)
"Our stay at Rodney’s cabin was just what we needed... Some time alone on 100 acres. Other than the peaceful sound of the waterfall trickling to the pond, Mother Nature and animals can only be heard. The cabin is equipped with everything you need to enjoy your stay as you reconnect with one another and the great outdoors. Bring whatever flavors you like and learn to cook together on a Big Green Egg that Rodney has built into his outdoor kitchen!! We relaxed in the hot tub each night and can’t...
United States
michael l.
The price is CA $277
CA $640 total
includes taxes & fees
Feb 9 - Feb 10
Secret SC Cabin on 100 acres Hot Tub Large Pond

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!
Marion
9.0 out of 10, Wonderful, (6 reviews)
"It was a great place. "
United States
Cindy N.
The price is CA $274
CA $814 total
includes taxes & fees
Feb 9 - Feb 10
Located in Marion. Only 1 hour from Myrtle Beach, 35 minutes from Florence!

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Perfect Stop • Near I-95, Downtown & Civic Center and Darlington
Florence
9.6 out of 10, Exceptional, (5 reviews)
The price is CA $293
CA $376 total
includes taxes & fees
Feb 11 - Feb 12
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Florence
10.0 out of 10, Exceptional, (43 reviews)
"I would definitely stay again! Great location."
United States
LaDara D.
The price is CA $309
CA $397 total
includes taxes & fees
Feb 15 - Feb 16
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

6 golf courses within 20 minutes, 30 foot camper with deck, firepit & BBQ

6 golf courses within 20 minutes, 30 foot camper with deck, firepit & BBQ
Loris
10.0 out of 10, Exceptional, (18 reviews)
"Hosts were wonderful and so was the property. I highly recommend this location."
United States
Lisa j.
6 golf courses within 20 minutes, 30 foot camper with deck, firepit & BBQ

Camden Cottage

Camden Cottage
Camden
10.0 out of 10, Exceptional, (57 reviews)
"Needs more stars! Perfect place to stay and owners are fabulous. Clean, spacious, quiet, and private. Its like home. I highly recommend!"
United States
Cass
The price is CA $135
CA $244 total
includes taxes & fees
Feb 15 - Feb 16
Camden Cottage

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE

Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
Camden
The price is CA $107
CA $212 total
includes taxes & fees
Feb 9 - Feb 10
Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Rembert
9.6 out of 10, Exceptional, (24 reviews)
"Would definitely stay here again! This property is very reasonably priced. Host was great in communication. It was just a lovely, peaceful, and safe place to stay! Wish we would have stayed longer! Thank you so very much."
United States
Josh M.
The price is CA $166
CA $341 total
includes taxes & fees
Feb 9 - Feb 10
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florence Hotel Reviews

Find out more about Florence

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Florence. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Florence?

Yes, we have vacation rentals in Florence close to Eastern Carolina Agricultural Fairgrounds, or you can choose a secluded option if you'd like a relaxing place to stay. Tourists like the array of shops and top-notch restaurants in Florence. You can also check out the entertainment venues while you're visiting.

What are some of the best vacation rentals in Florence?

Walking distance from one of South Carolina's top Medical centers.: Visitors give good reviews to this Florence vacation home rental, which offers a garden, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Other favorite homes for rent in Florence are Perfect Get-Away In The Heart Of Downtown Florence and Charming and Cozy 4BR 2BA House with Parking, Minutes from I-95 and Buc-ees.

How many vacation rentals will I find in Florence?

Choose from 35 Expedia vacation rentals in Florence for a memorable vacation.

What can I see and do in Florence?

Palmetto Shores Lake and Florence Veterans Park are a couple of scenic spots to enjoy the outdoors, whereas Florence Museum is one of the cultural attractions. Other places in town to visit include Dr. Eddie Floyd Tennis Center and Magnolia Mall.

What are vacation rentals like in Florence?

Vacation rentals are privately owned accommodations you can reserve for a couple days or more in Florence. Vacation rentals offer extras such as hot tubs, fire pits, and patios so you'll have a home away from home. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular choice for a family trip or a small group gathering.