Mayodan Vacation Packages
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- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
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Your Mayodan Vacation
When you book a Mayodan vacation package, you can really enjoy your adventure to the fullest. Delve into the best things about this fascinating city knowing that everything has been organized in advance. Can't wait to do a little sightseeing? Spend your days enjoying popular attractions such as Mayo River State Park during your trip to Mayodan. Don't put off exploring this destination any longer. The ultimate Mayodan vacation is a few quick clicks away with Expedia.
Mayodan Hotel Deals
Econo Lodge Martinsville
1755 Virginia Ave Martinsville VA
Fully refundableReserve now, pay when you stay
The price is CA $84 per night from Jun 9 to Jun 10
CA $84
CA $93 total
Jun 9 - Jun 10
includes taxes & fees
6.4/10 (508 reviews)
"We stayed here just passing through. The beds were clean, though there were small cigarette burns on some of the sheets. The rooms were secure and the premises quiet on the Friday night we stayed. We rented 2 rooms and one of them appeared to have mildew on the vent in the bathroom. One of the rooms ..."
Reviewed on May 21, 2026
Reidsville Inn & Suites
2100 Barnes St. Reidsville NC
Fully refundableReserve now, pay when you stay
The price is CA $75 per night from Jun 19 to Jun 20
CA $75
CA $83 total
Jun 19 - Jun 20
includes taxes & fees
6.8/10 (378 reviews)
"Thank you"
Reviewed on May 25, 2026
Quality Inn Reidsville Hwy 29
2203 Barnes Street Reidsville NC
Fully refundable
The price is CA $105 per night from May 28 to May 29
CA $105
CA $117 total
May 28 - May 29
includes taxes & fees
7/10 Good! (374 reviews)
"I enjoyed my stay. The tub was stained though. And the shower was tricky to turn on, but other than that - staff were friendly and helpful. No bugs seen, sheets appeared clean. Area was quiet. The breakfast looked and smelled good..I didn't eat any of it because I had other breakfast plans."
Reviewed on May 26, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Mayodan
Mayo River State Park
You can take time to visit Mayo River State Park during your travels to Mayodan. Wander the parks or discover the countryside in this family-friendly area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.