Mayo Vacation Packages
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to CA $4,200 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Mayo Vacation
Experience the unique character and personality of Mayo with a customized Mayo vacation package. From its rural countryside to its spectacular views, you'll never have a dull moment in this city. If seeing the sights is on your to-do list during your trip to Mayo, check out major attractions such as Lafayette Blue Springs State Park. Don't put off exploring this destination any longer. Your perfect Mayo vacation is a couple of clicks away with Expedia.
Mayo Hotel Deals
Suwannee River Rendezvous
828 NE Primrose Rd Mayo FL
The price is CA $35 per night from May 28 to May 29
CA $35
CA $57 total
May 28 - May 29
includes taxes & fees
8.6/10 Excellent! (28 reviews)
No, no,no, 11 feral cats loose on property. When there's Nothing good to say about a place or person it's more Honorable to say Nothing.
Reviewed on Apr 3, 2026
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo FL
The price is CA $61 per night from May 25 to May 26
CA $61
CA $92 total
May 25 - May 26
includes taxes & fees
9.8/10 Exceptional! (10 reviews)
Host was great, room was clean. Quiet and peaceful.
Reviewed on May 9, 2026
Cindys Motel
487 W Main St Mayo FL
Fully refundableReserve now, pay when you stay
The price is CA $111 per night from May 20 to May 21
CA $111
CA $120 total
May 20 - May 21
includes taxes & fees
8.8/10 Excellent! (130 reviews)
Easy parking. Friendly staff. We extended our stay and had to switch rooms. The 1st kingsize bad was great. But when we changed rooms the queen size bed sagged in the middle.
Reviewed on Mar 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
