A calm river surrounded by trees with Spanish moss, reflecting the clear blue sky.

Mayo Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Mayo vacation rentals

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Mayo
10.0 out of 10, Exceptional, (12 reviews)
"Had a great weekend away- it was just what me and my girlfriend needed."
United States
Mike S.
The price is CA $68
CA $132 total
includes taxes & fees
Jun 30 - Jul 1
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo
10.0 out of 10, Exceptional, (13 reviews)
"Fantastic property very quiet with very friendly animals."
United States
Hevrard
The price is CA $67
CA $123 total
includes taxes & fees
Jul 7 - Jul 8
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
Mayo
10.0 out of 10, Exceptional, (6 reviews)
"Love this little slice of heaven!"
United States
Crystal
The price is CA $66
CA $99 total
includes taxes & fees
Jun 30 - Jul 1
RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River
Mayo
9.8 out of 10, Exceptional, (57 reviews)
"Was there for a family reunion and was great for what we needed."
United States
Anonymous traveller
The price is CA $214
CA $431 total
includes taxes & fees
Jul 6 - Jul 7
The Best memories are made on the Suwannee River

The Chalet On the Suwannee River

The Chalet On the Suwannee River
Mayo
10.0 out of 10, Exceptional, (1 review)
"We were in the area to check out some local spring and loved the accessibility of this VRBO’s location. This property was amazing and super fun. Can’t wait to go back."
United States
Mandy B.
The price is CA $319
CA $386 total
includes taxes & fees
Jun 30 - Jul 1
The Chalet On the Suwannee River

SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
The price is CA $156
CA $195 total
includes taxes & fees
Jul 6 - Jul 7
SpringHouse at Convict Springs

A-frame on the Suwannee River Rendezvous

A-frame on the Suwannee River Rendezvous
Mayo
6.0 out of 10, (1 review)
"Overnight night enroute"
Canada
Doug M.
The price is CA $334
CA $404 total
includes taxes & fees
Jun 30 - Jul 1
A-frame on the Suwannee River Rendezvous

Pequeño Refugio Cerca de Rios

Pequeño Refugio Cerca de Rios
Fort White
9.4 out of 10, Exceptional, (8 reviews)
"This was the cutest, charming, little quaint home away from home we’ve stayed. We felt like it was home away from home. Everything was wonderful! "
United States
Tiffany
The price is CA $176
CA $226 total
includes taxes & fees
Jun 30 - Jul 1
Pequeño Refugio Cerca de Rios

3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs

3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs
Fort White
The price is CA $206
CA $402 total
includes taxes & fees
Jul 30 - Jul 31
3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs

3 Rivers Crystal Cabin 3 Bedrooms 2 Bathrooms ~ Nature Lovers Only

3 Rivers Crystal Cabin 3 Bedrooms 2 Bathrooms ~ Nature Lovers Only
Fort White
The price is CA $158
CA $468 total
includes taxes & fees
Jun 30 - Jul 1
3 Rivers Crystal Cabin 3 Bedrooms 2 Bathrooms ~ Nature Lovers Only

The Riverhead | Springs • Pavilion • Grill

The Riverhead | Springs • Pavilion • Grill
Fort White
9.6 out of 10, Exceptional, (14 reviews)
"Very close to springs and other attractions. Property was clean and very inviting on the inside. The beds were comfortable and the decor was very homey. Ample coffee and tea was provided and the kitchen was very equipped for cooking. Overall a really great way to enjoy the nearby springs. "
United States
Nicole
The price is CA $131
CA $376 total
includes taxes & fees
Jul 1 - Jul 2
The Riverhead | Springs • Pavilion • Grill

Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
9.8 out of 10, Exceptional, (6 reviews)
"Excellent place "
United States
Linay
The price is CA $87
CA $227 total
includes taxes & fees
Jul 1 - Jul 2
Nook at the Springs | Tiny Home • Full Kitchen

Riverfront Cabin, Ichetucknee River

Riverfront Cabin, Ichetucknee River
Fort White
9.8 out of 10, Exceptional, (29 reviews)
"The host communicated well, the beds were very comfy, the walkway to the river and dock(s) were a blast to play on, and the home felt inviting. We will try to stay here again."
United States
RJ R.
The price is CA $479
CA $1,047 total
includes taxes & fees
Jul 5 - Jul 6
Riverfront Cabin, Ichetucknee River

aMandala River Retreat

aMandala River Retreat
Fort White
10.0 out of 10, Exceptional, (1 review)
The price is CA $507
CA $1,111 total
includes taxes & fees
Jun 30 - Jul 1
aMandala River Retreat

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Branford
10.0 out of 10, Exceptional, (9 reviews)
"Very cozy, comfortable cabin with lots of activities. "
United States
Dorothy G.
The price is CA $227
CA $415 total
includes taxes & fees
Jul 6 - Jul 7
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Quiet Lakeside Escape - 32’ RV Retreat Near Ichetucknee Springs

Quiet Lakeside Escape - 32’ RV Retreat Near Ichetucknee Springs
Branford
10.0 out of 10, Exceptional, (1 review)
The price is CA $157
CA $201 total
includes taxes & fees
Jun 30 - Jul 1
Quiet Lakeside Escape - 32’ RV Retreat Near Ichetucknee Springs

Fish & Float at Natural Springs! Log Cabin in Bell

Fish & Float at Natural Springs! Log Cabin in Bell
3.0 star property
Bell
10.0 out of 10, Exceptional, (1 review)
"A very nice cabin tucked away! We mostly enjoyed the chickens visiting us on the porch during morning coffee! The cabin is about 20 mins from the Springs and grocery store/market. High Springs town about 30 mins. Bring your own ice…no ice maker. If you need anything at all, the owner lives on the large property and happy to help but does respect your privacy…never saw him and the check in process was seemless. Loved the stay and sure you will as well."
United States
Beth
The price is CA $277
CA $543 total
includes taxes & fees
Jul 6 - Jul 7
Fish & Float at Natural Springs! Log Cabin in Bell

Fish & Float at Natural Springs! Log Cabin in Bell

Fish & Float at Natural Springs! Log Cabin in Bell
Bell
10.0 out of 10, Exceptional, (1 review)
"The owner was very welcoming, very polite, very respectful. Saw a bunch of deer few hours after we arrived, and when it came to evening time we heard a bunch of owls. The owner made us feel like we were at home. Most beautiful scenery/ cabin we have ever stayed at. If I could, I would give this review more than 5 stars ,will definitely be coming back in near future."
United States
Shaun & Kristin Schaub
The price is CA $212
CA $543 total
includes taxes & fees
Jul 6 - Jul 7
Fish & Float at Natural Springs! Log Cabin in Bell

< 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
Old Town
The price is CA $155
CA $557 total
includes taxes & fees
Jun 30 - Jul 1
< 1 Mi From Suwannee River, Hideaway w/ Lanai

Nature + Music + Town - Cozy Farmhouse Retreat

Nature + Music + Town - Cozy Farmhouse Retreat
Live Oak
10.0 out of 10, Exceptional, (22 reviews)
"Just what we needed. Enjoyed our stay"
United States
Mark A.
The price is CA $201
CA $425 total
includes taxes & fees
Jul 6 - Jul 7
Nature + Music + Town - Cozy Farmhouse Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Mayo Hotel Reviews

Find out more about Mayo

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Mayo. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in Mayo?

Yes, we offer vacation rentals in Mayo close to Veteran's Memorial Park of Mayo, or you can select a more remote option if you're looking for a relaxing stay. Mayo is known for its parks.

What are some of the best vacation rentals that Mayo has to offer?

Suwannee River Retreat with Private Dock, Free Kayaks, and Fire pit: Visitors give good reviews to this Mayo vacation home rental, which is located on a river and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Make the most of the garden in this rental home to help you unwind.

How many vacation rentals are there in Mayo?

Expedia has 7 vacation rentals for your stay in Mayo.

What can I see and do in Mayo?

Suwannee River and Perry Spring are a couple of lovely local spots to enjoy the outdoors, whereas family-friendly attractions include Veteran's Memorial Park of Mayo. Other places in town to visit include Lafayette Blue Springs State Park and Allen Mill Pond Spring.

What are vacation rentals like in Mayo?

Vacation rentals are privately owned accommodations you can reserve for a short or long stay in Mayo. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll feel right at home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a small group gathering.