A calm river surrounded by trees with Spanish moss, reflecting the clear blue sky.

Mayo Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Mayo vacation rentals

1. Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo
9.4 out of 10, Exceptional, (21 reviews)
"Fantastic property very quiet with very friendly animals."
United States
Hevrard
The price is CA $63
CA $122 total
includes taxes & fees
Nov 19 - Nov 20
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

2. Beautiful memories are made on the Suwannee River in Mayo Fl

Beautiful memories are made on the Suwannee River in Mayo Fl
Mayo
The price is CA $193
CA $377 total
includes taxes & fees
Nov 16 - Nov 17
Beautiful memories are made on the Suwannee River in Mayo Fl

3. Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Mayo
9.4 out of 10, Exceptional, (19 reviews)
"Host was very accommodating!! The cabin and property have everything you need to enjoy your stay."
United States
Sheila S.
The price is CA $76
CA $130 total
includes taxes & fees
Nov 16 - Nov 17
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

4. RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house
Mayo
8.8 out of 10, Excellent, (8 reviews)
"Love this little slice of heaven!"
United States
Crystal
The price is CA $78
CA $101 total
includes taxes & fees
Nov 16 - Nov 17
RV with 1full bed 2twin beds and AC WiFi smart TV bathroom outdoor shower house

5. SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
10.0 out of 10, Exceptional, (1 review)
The price is CA $157
CA $185 total
includes taxes & fees
Nov 16 - Nov 17
SpringHouse at Convict Springs

6. The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River
Mayo
9.8 out of 10, Exceptional, (59 reviews)
"Was there for a family reunion and was great for what we needed."
United States
Anonymous traveller
The price is CA $154
CA $343 total
includes taxes & fees
Nov 16 - Nov 17
The Best memories are made on the Suwannee River

7. The Chalet On the Suwannee River

The Chalet On the Suwannee River
Mayo
10.0 out of 10, Exceptional, (1 review)
"We were in the area to check out some local spring and loved the accessibility of this VRBO’s location. This property was amazing and super fun. Can’t wait to go back."
United States
Mandy B.
The price is CA $321
CA $372 total
includes taxes & fees
Nov 16 - Nov 17
The Chalet On the Suwannee River

8. A-frame on the Suwannee River Rendezvous

A-frame on the Suwannee River Rendezvous
Mayo
6.0 out of 10, (1 review)
"Overnight night enroute"
Canada
Doug M.
The price is CA $335
CA $389 total
includes taxes & fees
Nov 16 - Nov 17
A-frame on the Suwannee River Rendezvous

9. The Happy House Tiny Guest House

The Happy House Tiny Guest House
Live Oak
8.6 out of 10, Excellent, (8 reviews)
"very nice tiny house style accommodation"
United States
Cara B.
The price is CA $127
CA $196 total
includes taxes & fees
Nov 16 - Nov 17
The Happy House Tiny Guest House

10. Kokomo Farms - Cozy Cottage on the Farm

Kokomo Farms - Cozy Cottage on the Farm
Live Oak
9.8 out of 10, Exceptional, (15 reviews)
"Great place for nature!"
United States
Stephen
The price is CA $156
CA $227 total
includes taxes & fees
Nov 16 - Nov 17
Kokomo Farms - Cozy Cottage on the Farm

11. Suwannee Music Park about 30 mins away. Royal Springs across the street.

Suwannee Music Park about 30 mins away. Royal Springs across the street.
O'Brien
9.6 out of 10, Exceptional, (7 reviews)
"Had a great time there for the holiday weekend.."
United States
Karen L.
The price is CA $199
CA $490 total
includes taxes & fees
Nov 22 - Nov 23
Suwannee Music Park about 30 mins away. Royal Springs across the street.

12. Woodland Cabin on 21 Acres Cozy & Peaceful

Woodland Cabin on 21 Acres Cozy & Peaceful
Live Oak
10.0 out of 10, Exceptional, (38 reviews)
"Fantastic place, super clean and dreamy! We had an amazing stay"
United States
Maria C.
The price is CA $166
CA $282 total
includes taxes & fees
Nov 30 - Dec 1
Woodland Cabin on 21 Acres Cozy & Peaceful

13. The Sea Shed

The Sea Shed
Perry
10.0 out of 10, Exceptional, (14 reviews)
"The Sea Shack was perfect for my husband and I to stay while visiting family."
United States
Sheila
The price is CA $107
CA $233 total
includes taxes & fees
Nov 19 - Nov 20
The Sea Shed

14. Cozy House, Hot Tub & Close to FL Springs

Cozy House, Hot Tub & Close to FL Springs
Branford
10.0 out of 10, Exceptional, (2 reviews)
"Juan was so welcoming. The house was clean and had everything we needed for a fun family getaway - and then some! Would love to stay here again. "
United States
Ashley L.
The price is CA $214
CA $372 total
includes taxes & fees
Nov 17 - Nov 18
Cozy House, Hot Tub & Close to FL Springs

15. Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
10.0 out of 10, Exceptional, (12 reviews)
"This place was very nice and clean. It had everything we needed. Its also very close to the Springs. Definitely recommend."
United States
Natasha
The price is CA $94
CA $225 total
includes taxes & fees
Nov 16 - Nov 17
Nook at the Springs | Tiny Home • Full Kitchen

16. The Holy Mackerel Family and pet friendly

The Holy Mackerel Family and pet friendly
Perry
9.8 out of 10, Exceptional, (16 reviews)
"Perfect location, nice comfortable stay with incredible host!!"
United States
Brian
The price is CA $113
CA $239 total
includes taxes & fees
Nov 16 - Nov 17
The Holy Mackerel Family and pet friendly

17. Peaceful 3BR/2BA Near Suwannee River & Springs

Peaceful 3BR/2BA Near Suwannee River & Springs
Live Oak
9.2 out of 10, Wonderful, (5 reviews)
The price is CA $167
CA $284 total
includes taxes & fees
Nov 29 - Nov 30
Peaceful 3BR/2BA Near Suwannee River & Springs

18. Cottage Charm Retreat: Porch, Near Downtown

Cottage Charm Retreat: Porch, Near Downtown
3.0 star property
Live Oak
The price is CA $275
CA $620 total
includes taxes & fees
Dec 1 - Dec 2
Cottage Charm Retreat: Porch, Near Downtown

19. MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
O'Brien
9.4 out of 10, Exceptional, (60 reviews)
"A great get away for Labor Day weekend to do a little jet skiing with friends on the river and visiting all the local springs!"
United States
Heather H.
The price is CA $213
CA $506 total
includes taxes & fees
Nov 22 - Nov 23
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

20. Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Live Oak
10.0 out of 10, Exceptional, (88 reviews)
"We loved our stay, we only booked for a night, but will definitely be back for a longer stay. The house was spotless, beds were super comfy. My son loved fishing, and playing games. The property is beautiful."
United States
Savannah C.
The price is CA $191
CA $340 total
includes taxes & fees
Nov 23 - Nov 24
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Mayo Hotel Reviews

Find out more about Mayo

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Mayo. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in Mayo?

Yes, we offer vacation rentals in Mayo close to Veteran's Memorial Park of Mayo, or you can select a more remote option if you're looking for a relaxing stay. Mayo is known for its parks.

What are some of the best vacation rentals that Mayo has to offer?

ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River: This vacation home rental outside of Mayo is located on a river and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 4 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family.

How many vacation rentals are there in Mayo?

Expedia has 8 vacation rentals for your stay in Mayo.

What can I see and do in Mayo?

Family-friendly attractions include Veteran's Memorial Park of Mayo, whereas Suwannee River is a spot to enjoy the outdoors. Other places in town to visit include Lafayette Blue Springs State Park and Lafayette County Library.

What are vacation rentals like in Mayo?

Vacation rentals are privately owned accommodations you can reserve for a short or long stay in Mayo. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll feel right at home. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a small group gathering.