Title: Mayo Vacation Packages & Trips 2026 | Expedia.ca [Hotels in Mayo](https://expedia.ca/Mayo-Hotels.d6286979.Travel-Guide-Hotels)[Vacation Rentals in Mayo](https://expedia.ca/Mayo-Vacation-Rentals.d6286979.Travel-Guide-VacationRentals)[Mayo Car Rentals](https://expedia.ca/Car-Rentals-In-Mayo.d6286979.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6286979/5dd23773-1205-4776-836a-48316c56dcec.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mayo Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place #### Your Mayo Vacation Experience the unique character and personality of Mayo with a customized Mayo vacation package. From its rural countryside to its spectacular views, you'll never have a dull moment in this city. If seeing the sights is on your to-do list during your trip to Mayo, check out major attractions such as [Lafayette Blue Springs State Park](https://www.expedia.ca/Lafayette-Blue-Springs-State-Park-Mayo.d553248621532654049.Vacation-Attraction). Don't put off exploring this destination any longer. Your perfect Mayo vacation is a couple of clicks away with Expedia. ## Ready to book your vacation to Mayo? Choose your dates ## Mayo Hotel Deals ![Suwannee River Rendezvous](https://images.trvl-media.com/lodging/112000000/111770000/111760600/111760596/994169e1_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Suwannee River Rendezvous 828 NE Primrose Rd Mayo FL CA $37 CA $59 total Mar 25 - Mar 26 includes taxes & fees 8.8/10 Excellent! (25 reviews) Room was clean and beds were memory foam. There was no table in my room, so I had to eat dinner sitting on my bed. Reviewed on Mar 20, 2026 [](https://expedia.ca/Hotel-Search?startDate=25%2F03%2F2026&endDate=26%2F03%2F2026&selected=111760596&PinnedHotelID=111760596&HadPinnedHotel=true®ionId=6286979) ![Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,](https://images.trvl-media.com/lodging/118000000/117030000/117028300/117028207/b939a190_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi, Mayo FL CA $60 CA $92 total Mar 29 - Mar 30 includes taxes & fees 9.8/10 Exceptional! (6 reviews) Nice and pet friendly Reviewed on Mar 7, 2026 [](https://expedia.ca/Hotel-Search?startDate=29%2F03%2F2026&endDate=30%2F03%2F2026&selected=117028207&PinnedHotelID=117028207&HadPinnedHotel=true®ionId=6286979) ![Cindys Motel](https://images.trvl-media.com/lodging/40000000/39450000/39448900/39448879/f9b4a9c4_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Cindys Motel 487 W Main St Mayo FL Fully refundableReserve now, pay when you stay 8.8/10 Excellent! (130 reviews) Easy parking. Friendly staff. We extended our stay and had to switch rooms. The 1st kingsize bad was great. But when we changed rooms the queen size bed sagged in the middle. Reviewed on Mar 11, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=07%2F04%2F2026&endDate=08%2F04%2F2026&selected=39448879&PinnedHotelID=39448879&HadPinnedHotel=true®ionId=6286979) [](https://expedia.ca/Hotel-Search?startDate=07%2F04%2F2026&endDate=08%2F04%2F2026&selected=39448879&PinnedHotelID=39448879&HadPinnedHotel=true®ionId=6286979) [See all 474 properties in Mayo](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=25%2F03%2F2026&endDate=26%2F03%2F2026®ionId=6286979) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app