Name: 21C Museum Hotel St Louis
Price range: CA $234
Rating: 9

Your Maryville Vacation

From its lively atmosphere to its spectacular views and beyond, there's plenty to love about Maryville. Uncover the delights of this awesome city with a Maryville vacation package that's made for you. A trip to Maryville is a wonderful opportunity to do a bit of sightseeing. Be sure to look around well-known attractions like Edwardsville Arts Center, Horseshoe Lake State Park and Villa Marie Winery & Banquet Center. Stop daydreaming and start traveling. Explore the multitude of options on Expedia today and finally put your Maryville vacation plans into motion!

Top Maryville Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

CA $889

per person

Jun 12 - Jun 15

found 15 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

8.8/10 Excellent! (1,049 reviews)

Everything was great! Hotel is beautiful, staff was so friendly, perfect trip!

Reviewed on Apr 6, 2026

The Wildwood Hotel

CA $931

per person

Jun 12 - Jun 15

found 15 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

9.2/10 Wonderful! (1,627 reviews)

The breakfaat was average, thou fresh. There was enough street parking nearby, safe.

Reviewed on Mar 30, 2026

The Cheshire

CA $958

per person

Jun 12 - Jun 15

found 15 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

8.6/10 Excellent! (1,011 reviews)

It had unique decor which was fun. Staff was nice But the lights were broken and there was a leftover can under a chair

Reviewed on Apr 1, 2026

The Royal Sonesta Chase Park Plaza St. Louis

Central West End

CA $1,000

per person

Jun 12 - Jun 15

found 15 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

9/10 Wonderful! (1,008 reviews)

Beautiful hotel - three phenomenal restaurants. Perfect location. We absolutely love The Chase Park Plaza.

Reviewed on Apr 6, 2026

Hollywood Casino & Hotel St. Louis

CA $1,093

per person

Jun 12 - Jun 15

found 15 hours ago

Roundtrip non-stop flight included

Calgary (YYC) to St. Louis (STL)

8.4/10 Very Good! (2,194 reviews)

Room was clean, shuttle was there timely

Reviewed on Apr 9, 2026

Ready to book your vacation to Maryville?

Choose your dates

Maryville Hotel Deals

Drury Plaza Hotel St. Louis at the Arch

2 South 4th Street St. Louis MO

Fully refundableReserve now, pay when you stay

CA $249

CA $291 total

Apr 12 - Apr 13

includes taxes & fees

9.4/10 Exceptional! (3,370 reviews)

Unkown

Reviewed on Apr 9, 2026

Pear Tree Inn St. Louis Near Union Station

2211 Market Street St. Louis MO

Fully refundableReserve now, pay when you stay

CA $173

CA $202 total

Apr 13 - Apr 14

includes taxes & fees

8.8/10 Excellent! (1,933 reviews)

TV lost signal for hours the 2 nights we stayed during the ncaa basketball tournament. Was not happy at all!

Reviewed on Apr 9, 2026

21C Museum Hotel St Louis

1528 Locust street St. Louis MO

Fully refundableReserve now, pay when you stay

CA $234

CA $281 total

Apr 19 - Apr 20

includes taxes & fees

9/10 Wonderful! (1,738 reviews)

Beautiful, repurposed hotel with gorgeous lobby, amazing art museum, top-notch pool and spa facilities, central location, and very comfortable and compact room. We will definitely stay here again if we find another great deal!

Reviewed on Apr 9, 2026

See all 1,473 properties in Maryville

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.