Madre de Dios Region Vacation Packages

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Your Madre de Dios Region Vacation

Choose one of our vacation packages to Madre de Dios Region and wander wherever your adventurous soul takes you. Hiking and nature are just a couple of the things you can look forward to in this wonderful destination. Start your trip to Madre de Dios Region by spending a few nights in Tambopata, one of the top cities here. Expedia has hotels, flights and all your other travel needs to help you curate your very own customized Madre de Dios Region vacation today.

Madre de Dios Region Hotel Deals

Dmilez Hotel

Dmilez Hotel

2.5 out of 5
Psj. Tupac Amaru, Mz. E, Lot 6, A.H.8 de Octubre, Tambopata, Madre de Dios
The price is CA $42 per night from Aug 1 to Aug 2
CA $42
CA $42 total
Aug 1 - Aug 2
6.6/10 (20 reviews)
"5 stories, no elevator, could not communicate with desk staff in english or basic spanish"

Reviewed on Oct. 21, 2024

Dmilez Hotel
IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

3 out of 5
Tambopata KM. 7 Otr. Carretera Bajo, Tambopata, Madre de Dios
The price is CA $297 per night from Aug 20 to Aug 21
CA $297
CA $313 total
Aug 20 - Aug 21
9/10 Wonderful! (4 reviews)
"Beautiful location on the river, staff and guides were great, the ask inclusive feature was very convenient. A little bit difficult to get to but would recommend. Food was average but service and attentiveness made up for it."

Reviewed on May 25, 2025

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429, Tambopata, Madre de Dios
Fully refundableReserve now, pay when you stay
The price is CA $52 per night from Jul 22 to Jul 23
CA $52
CA $52 total
Jul 22 - Jul 23
9.4/10 Exceptional! (16 reviews)
"Great stay, friendly owners and staff."

Reviewed on Jun. 22, 2025

Libelula Hotel
See all 54 properties in Madre de Dios Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Family Vacations

Family Vacations

Frequently asked questions

How much does a Madre de Dios Region vacation package cost?
Choose from any combination of hotels, flights and car rentals, and you can be vacationing in Madre de Dios Region from just . And the more you bundle, the more money you save. The getaway of your dreams has never been more affordable.
How do I get a cheap travel package to Madre de Dios Region?
Browse and book everything all in one place with our Madre de Dios Region vacation packages. We have incredible bargains on hotels, flights and more that'll keep your pocket happy and your sense of adventure alive. And, with more than 550 airlines and 1,000,000 properties throughout the world to pick from, you'll have endless opportunities to mix and match as you please.
What are the top hotels in Madre de Dios Region?
For properties in Tambopata with friendly service and cozy beds, you can't beat Kapievi Ecovillage and Inkaterra Reserva Amazonica. If you plan to explore Las Piedras as well, you'll get a solid night's sleep at Copasu Hotel or Tarantula Hostel.
How far in advance should I book my Madre de Dios Region vacation?
Reward yourself with the biggest variety and the lowest prices by booking your vacation to Madre de Dios Region nice and early. Airlines generally advertise flight tickets around 12 months prior to departure, so reserve your spot ASAP. Having said that, Expedia is constantly working to give you the best deals around, so it's never a bad time to book your dream vacation!
What does an Expedia Madre de Dios Region travel package include?
Hotels, flights and car rentals — we connect you to the very best bargains. All you have to do is decide on your favorite combination. After you've made your booking, you can add on the fun stuff like sightseeing activities. Our travel packages make it easy to create an awesome Madre de Dios Region getaway.
What should I know before booking a Madre de Dios Region travel package?
When you book your flights, hotels and car rentals together, you'll enjoy amazing discounts. Whether you're planning a mountain getaway in a cabin or want to stay in a cozy apartment in the city, Expedia will help make it happen.
Can I choose my airline with a Madre de Dios Region Expedia vacation package?
Yes — and it's easy too. Expedia has access to more than 550 partner airlines globally. Our packages give you the flexibility to pick from available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Madre de Dios Region vacation package?
It's difficult to predict what tomorrow might bring, so it's comforting to know that you can cancel or change your Madre de Dios Region vacation package. If you booked in the last 24 hours, you may be entitled to a refund. If your booking is older, your airline, hotel or car rental company may charge a fee. Check our Customer Service Portal to find out more.

Discover the most popular places to visit in Madre de Dios Region

Manu National Park

Explore the great outdoors at Manu National Park, a lovely green space in Manu.

Manu National Park

Collpa La Cachuela

You can take time to visit Collpa La Cachuela during your travels to Puerto Maldonado. Wander the riverfront and forest while you're in the area.

Collpa La Cachuela

What to do in Madre de Dios Region

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

Puerto Maldonado: 4-Day Tambopata Rainforest Tour

CA $599
per adult
Puerto Maldonado: 4-Day Tambopata Rainforest Tour
Deluxe Sandoval lake and overlook tower

Sandoval lake and Tambopata national reserve

CA $112
per adult
Sandoval lake and Tambopata national reserve
Tambopata Jungle Adventure Tour 4 Days

Tambopata Jungle Adventure Tour 4 Days

CA $613
per adult
Tambopata Jungle Adventure Tour 4 Days
See all activities in Madre de Dios Region
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.