Title: Book the Best Macon WINERY Hotels in 2025 | Expedia.ca [Hotels in Macon](https://expedia.ca/Macon-Hotels.d6058819.Travel-Guide-Hotels)[Vacation Rentals in Macon](https://expedia.ca/Macon-Vacation-Rentals.d6058819.Travel-Guide-VacationRentals)[Flights to Macon](https://expedia.ca/Cheap-Flights-To-Macon.d6058819.Travel-Guide-Flights)[Macon Car Rentals](https://expedia.ca/Car-Rentals-In-Macon.d6058819.Car-Rental-Guide)[Macon Vacation Packages](https://expedia.ca/Macon.d6058819.Destination-Travel-Guides) ![Default HTG hotel image](https://media.expedia.com/media/content/shared/images/travelguides/sem-hotels-tablet.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Winery Hotels in Macon, MO from CA $141 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Macon Winery Hotels Tonight [Oct 12 - Oct 13](https://www.expedia.ca/Hotel-Search?regionId=6058819&startDate=2025-10-12&endDate=2025-10-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 13 - Oct 14](https://www.expedia.ca/Hotel-Search?regionId=6058819&startDate=2025-10-13&endDate=2025-10-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=6058819&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=6058819&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Macon Winery Hotels ![Indoor pool](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/6c9e28fd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Double Room, 2 Queen Beds, Refrigerator & Microwave, Ground Floor](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/1b0e35e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/76b9d2c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/b11f297e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Depot Inn and Suites La Plata 9.8/10 Exceptional (589) "Very clean and nice hotel. Friendly staff as well!" [](https://www.expedia.ca/La-Plata-Hotels-Depot-Inn-And-Suites.h1790806.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/17367649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/781fda5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/a8e8f4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/19000000/18060000/18057900/18057874/35d9f717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Kirksville - University Area by IHG Kirksville 9.2/10 Wonderful (491) "Good breakfast. Clean. " CA $167 CA $189 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Macon-Hotels-Holiday-Inn-Express-Suites-Kirksville-University-Area.h18057874.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/96000000/95760000/95757800/95757739/7540a820.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/96000000/95760000/95757800/95757739/ef782d7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hair dryer, towels](https://images.trvl-media.com/lodging/96000000/95760000/95757800/95757739/2d405378.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95760000/95757800/95757739/620f5618.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### All Start Queen Room at Hotel Marceline Marceline CA $103 CA $141 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Marceline-Hotels-All-Start-Queen-Room-At-Hotel-Marceline.h95757739.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/91000000/90990000/90985500/90985489/93a0539b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/91000000/90990000/90985500/90985489/caa68627.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace, books, video library](https://images.trvl-media.com/lodging/91000000/90990000/90985500/90985489/e0ed7f90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/91000000/90990000/90985500/90985489/09f030bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Disney Inspired Retreat at Hotel Marceline Marceline 9.4/10 Exceptional (8) "Room itself was great. Fun theming and a good size for my family. It listed a washer and dryer and that is not accurate. Communication was non existent online. I had to call and they were very confused. Overall good though. " CA $200 CA $279 total includes taxes & fees Oct 15 - Oct 16 [](https://www.expedia.ca/Marceline-Hotels-Disney-Inspired-Retreat-At-Hotel-Marceline.h90985489.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/96000000/95730000/95728900/95728848/793ca680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/96000000/95730000/95728900/95728848/fe9f1a1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/96000000/95730000/95728900/95728848/cb9b2723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95730000/95728900/95728848/dad6ca5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Animal Kingdom Room at Hotel Marceline Marceline 8.0/10 Very good (4) "Very clean place and excellent hosts. Beautiful little town." CA $116 CA $162 total includes taxes & fees Oct 13 - Oct 14 [](https://www.expedia.ca/Marceline-Hotels-Animal-Kingdom-Room-At-Hotel-Marceline.h95728848.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-26&endDate=2025-10-27®ionId=6058819&adults=2&location_highlights_explore=winery&sort=RECOMMENDED&openPlayBack=true) ## Top Macon Hotel Reviews ![Depot Inn and Suites](//images.trvl-media.com/lodging/2000000/1800000/1790900/1790806/6c9e28fd_y.jpg) ### Depot Inn and Suites 10/10 Excellent "Depot Inn is very, very nice, clean, the staff are very nice and helpful. We have stayed there many times and it has always been the same, excellent." 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