Find Spa Hotels in Macon, MO from CA $54

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Check prices for these dates

Tonight
Nov 12 - Nov 13
Tomorrow
Nov 13 - Nov 14
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22
No exact matches found, but these alternatives could be just right

Recommended hotels in Macon

A stainless steel ice dispenser with a blue button labeled 'PUSH FOR ICE' in a kitchen setting.

1. Travelier Motel

Travelier Motel
2.5 star property
Macon
7.6 out of 10, Good, (428 reviews)
The price is CA $55
CA $65 total
includes taxes & fees
Nov 28 - Nov 29
Travelier Motel
A hotel room with a bed, a sofa, a desk, a chair, and a small table.

2. Super 8 by Wyndham Macon

Super 8 by Wyndham Macon
2.0 star property
Macon
7.8 out of 10, Good, (743 reviews)
The price is CA $106
CA $116 total
includes taxes & fees
Dec 6 - Dec 7
Super 8 by Wyndham Macon
A compact kitchen with wooden cabinets, a coffee machine, and a dining area with metal chairs.

3. Americas Best Value Inn & Suites Macon at Sunset Dr

Americas Best Value Inn & Suites Macon at Sunset Dr
2.0 star property
Macon
6.8 out of 10, (389 reviews)
The price is CA $102
CA $109 total
includes taxes & fees
Nov 26 - Nov 27
Americas Best Value Inn & Suites Macon at Sunset Dr
An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

4. Depot Inn and Suites

Depot Inn and Suites
3.5 star property
La Plata
9.8 out of 10, Exceptional, (752 reviews)
The price is CA $112
CA $122 total
includes taxes & fees
Dec 13 - Dec 14
Depot Inn and Suites
A hotel room with a large bed, a separate sitting area, a bathtub, and a view of the outdoors.

5. Comfort Inn & Suites Moberly

Comfort Inn & Suites Moberly
2.5 star property
Moberly
8.4 out of 10, Very good, (468 reviews)
The price is CA $168
CA $189 total
includes taxes & fees
Dec 2 - Dec 3
Comfort Inn & Suites Moberly
A buffet with various food items, including omelets and other dishes, arranged in metal serving trays.

6. Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (582 reviews)
The price is CA $162
CA $183 total
includes taxes & fees
Nov 29 - Nov 30
Holiday Inn Express & Suites Kirksville - University Area by IHG
A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

7. Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
2.5 star property
Kirksville
8.8 out of 10, Excellent, (295 reviews)
The price is CA $92
CA $104 total
includes taxes & fees
Dec 6 - Dec 7
Super 8 by Wyndham Kirksville-University Area
A hotel room with a large bathtub, a bed, a desk, and a television.

8. Baymont by Wyndham Kirksville University Area

Baymont by Wyndham Kirksville University Area
2.5 star property
Kirksville
7.6 out of 10, Good, (963 reviews)
The price is CA $90
CA $102 total
includes taxes & fees
Nov 25 - Nov 26
Baymont by Wyndham Kirksville University Area
A modern hotel lobby with multiple seating areas, including a bar and dining tables.

9. Hampton Inn Kirksville

Hampton Inn Kirksville
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (709 reviews)
The price is CA $162
CA $183 total
includes taxes & fees
Nov 28 - Nov 29
Hampton Inn Kirksville
A living room with a brown sofa, a wooden coffee table, a television on a stand, and a bookshelf.

10. Unwind on Vine

Unwind on Vine
Macon
9.6 out of 10, Exceptional, (38 reviews)
The price is CA $241
CA $366 total
includes taxes & fees
Dec 5 - Dec 6
Unwind on Vine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Macon

Pool
Breakfast included

Top Macon Hotel Reviews

A modern hotel lobby with multiple seating areas, including a bar and dining tables.
Hampton Inn Kirksville

Hampton Inn Kirksville

Hampton Inn Kirksville
Kirksville

10/10 Excellent

I had a great stay at this hotel. The property was very clean and well maintained. The staff were friendly. The breakfast was fresh and offered a good variety of options. The room was comfortable, quiet, and equipped with everything I needed. The location was convenient, and the overall atmosphere made my stay enjoyable. I would definitely stay here again and recommend it to others.
Canada
Phebe
Reviewed June 8, 2026
Hampton Inn Kirksville

Frequently Asked Questions

Looking for a spa hotel in Macon?

Forget the stress of everyday life and book yourself a lush spa hotel. Check out the theater scene and churches in Macon—your cultural tour starts here. Be sure to pay a visit to the monuments during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your holiday.

What's there to see and do in Macon?

When you're in Macon, enjoy exploring the sights and attractions here including Long Branch State Park, Maples Repertory Theatre, and West Winery. If you have a little extra time during your trip, you might want to make a stop at La Plata Golf Course and Stephen's Park.

What is a Macon spa hotel?

Spa hotels in Macon provide lodging and have an on-site spa offering services including couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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