Lee County Vacation Rentals

Compare and save

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Featured Vacation Homes in Lee County

Our top choices for Lee County vacation homes

The Tiny: 2-BR, Lake Wateree Sunsets + Shared Boat Ramp & Dock!

9.4 out of 10, Exceptional, (17)
"Enjoyed our time at a very special place. A really great place to stay. "
The Tiny: 2-BR, Lake Wateree Sunsets + Shared Boat Ramp & Dock!

Remodeled home with firepit and only 9 minutes from downtown area!

9.6 out of 10, Exceptional, (17)
"The place was great, the neighborhood was quite and peaceful. I will be using them again thank you for the beautiful stay"
Remodeled home with firepit and only 9 minutes from downtown area!

Charming 3-bedroom house in wonderful Sumter

2.0 star property
8.8 out of 10, Excellent, (14)
"Cute, quiet, homey property. We had a nice stay!"
Charming 3-bedroom house in wonderful Sumter

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

10.0 out of 10, Exceptional, (26)
"Excellent house and property. Would definitely stay here again!"
The price is CA $326
CA $414 total
includes taxes & fees
Sep 4 - Sep 5
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Pineapple House: Historic. Southern Charm. Walk Downtown.

9.4 out of 10, Exceptional, (16)
"This was a very nice property and very comfortable. We enjoyed our stay there."
Pineapple House: Historic. Southern Charm. Walk Downtown.

Peaceful, Country living! Beautiful view from front porch!

10.0 out of 10, Exceptional, (5)
"This was the perfect stay for our trip to CMP. The House was very clean and set up well for our stay. The Host was very responsive to questions. "
Peaceful, Country living! Beautiful view from front porch!

'Vibe Villa' w/ Backyard ~ 8 Mi to Shaw AFB!

10.0 out of 10, Exceptional, (8)
"Enjoyed our stay. We will definitely return!"
'Vibe Villa' w/ Backyard ~ 8 Mi to Shaw AFB!

Unique Camden Waterfront w/ Spectacular Views!

9.4 out of 10, Exceptional, (35)
"Great location great lake"
Unique Camden Waterfront w/ Spectacular Views!

Lake Front 6 Bedroom Home on Beautiful Lake Wateree.

10.0 out of 10, Exceptional, (44)
"The property is absolutely beautiful and the host was extremely "
Lake Front 6 Bedroom Home on Beautiful Lake Wateree.

Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

9.6 out of 10, Exceptional, (23)
"Beautiful gem in a country setting. Can't wait to find a reason to stay again."
The price is CA $218
CA $363 total
includes taxes & fees
Sep 1 - Sep 2
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly

The Cottage: 2-BR, Sunset Side of Lake Wateree Ramp + Priv Dock!

9.6 out of 10, Exceptional, (80)
"We love this place! Can’t wait to go back! "
The Cottage: 2-BR, Sunset Side of Lake Wateree Ramp + Priv Dock!

New, Oasis Haven near downtown & Shaw AFB

10.0 out of 10, Exceptional, (4)
"Lovely homr"
New, Oasis Haven near downtown & Shaw AFB

Waterfront/ Lower Dam/ Stunning Lake Wateree views! Near Buckhill Landing/Lugoff

9.6 out of 10, Exceptional, (16)
"Great location, beautiful lake, clean and easy access in. Thanks"
Waterfront/ Lower Dam/ Stunning Lake Wateree views! Near Buckhill Landing/Lugoff

Cozy comfortable home near lakes, parks and downtown Sumter

9.8 out of 10, Exceptional, (50)
"House is exactly how it’s described in the listing. Very clean and comfortable. The beds were so comfortable too! Host was superb and accommodating! We will definitely book here again! "
Cozy comfortable home near lakes, parks and downtown Sumter

Hickory Haven 3Br Elegant Downtown Hidden Gem

9.6 out of 10, Exceptional, (19)
"We stayed at the house for the Darlington race weekend. It was pretty close to the racetrack and was great size for what we needed. Not the best area but the house was great. "
Hickory Haven 3Br Elegant Downtown Hidden Gem

Spacious Cozy 4 BR Home w/ Wi-Fi & Free Parking

8.6 out of 10, Excellent, (9)
"Due to the passing of the family matriarch who was born and raised in the same hometown where this house stay was... the NYC family traveled down to attend the services."
Spacious Cozy 4 BR Home w/ Wi-Fi & Free Parking

Spacious 3-bedroom home in natural setting

8.0 out of 10, Very good, (1)
"This host is outstanding. She is so gracious and easy to work with. The home is very clean with everything you need. The beds are super comfortably with top notch linens. She has so many extras in this home. I highly recommend this home to anyone in the area. Quite and peaceful area. There was an added treat waiting when arrived that so appreciated. Peaches and a loaf of bread. This host goes all out to make you feel at home. 10 stars"
Spacious 3-bedroom home in natural setting

The Vista: 3-BR, Sunsets over Lake Wateree - 3 Bedroom w DOCK!

3.5 star property
9.8 out of 10, Exceptional, (26)
"Great location. Not far from Camden. Loved fishing off the dock ! "
The Vista: 3-BR, Sunsets over Lake Wateree - 3 Bedroom w DOCK!

Charming home away from home 2-bed 2-bath house with WiFi, AC in lovely Sumter

2.0 out of 10, (1)
"Property owner non responsive and property not available for stay after we drove 5 hrs to visit son on deployment with army. After repeated calls host finally answered and did notify Travelocity of non availability so was able to get money refunded but was pretty inconvenient "
The price is CA $166
CA $327 total
includes taxes & fees
Aug 27 - Aug 28
Charming home away from home 2-bed 2-bath house with WiFi, AC in lovely Sumter

Cheerful home with plenty of privacy and entertainment room.

8.2 out of 10, Very good, (25)
"We had a wonderful stay. Three couples in for the race, house was perfect. "
Cheerful home with plenty of privacy and entertainment room.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Lee County Hotel Reviews

Find out more about Lee County

Find out more about Lee County

Lee County Vacation Homes information

Number of reviews
466
Accommodation
58 Vacation Homes
Lowest Price
CA $137
Highest Price
CA $326

Explore a world of travel with Expedia

Explore a world of travel with Expedia