Lee County Vacation Rentals

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Our top choices for Lee County vacation rentals

9.8 out of 10, Exceptional, (45 reviews)
"Everything was great!"
United States
Debra B.
The price is CA $140
CA $264 total
includes taxes & fees
Mar 9 - Mar 10
Walking distance from one of South Carolina's top Medical centers.

Cottage in Hartsville

Cozy Blue Cottage 2BR/1BA
9.0 out of 10, Wonderful, (8 reviews)
"Enjoyed my time in Hartsville with family "
United States
Lori
The price is CA $149
CA $319 total
includes taxes & fees
Mar 9 - Mar 10
Cozy Blue Cottage 2BR/1BA

Vacation Home in Camden

Camden Cottage
10.0 out of 10, Exceptional, (59 reviews)
"Needs more stars! Perfect place to stay and owners are fabulous. Clean, spacious, quiet, and private. Its like home. I highly recommend!"
United States
Cass
The price is CA $134
CA $242 total
includes taxes & fees
Mar 15 - Mar 16
Camden Cottage
10.0 out of 10, Exceptional, (4 reviews)
"Cool loft! Convenient location, a drive will be in order to get downtown to the square. Quiet neighborhood."
United States
Taylor B.
The price is CA $133
CA $255 total
includes taxes & fees
Mar 9 - Mar 10
Historic Camden Showstopper!! THE LITTLE GARDNER’S COTTAGE
9.6 out of 10, Exceptional, (24 reviews)
"Would definitely stay here again! This property is very reasonably priced. Host was great in communication. It was just a lovely, peaceful, and safe place to stay! Wish we would have stayed longer! Thank you so very much."
United States
Josh M.
The price is CA $183
CA $363 total
includes taxes & fees
Mar 23 - Mar 24
Pear Tree Farm. Peaceful, Country living at its best. 12 stables. Pet Friendly
8.8 out of 10, Excellent, (3 reviews)
"Convenient location"
United States
Bonney W.
The price is CA $204
CA $691 total
includes taxes & fees
Mar 9 - Mar 10
Charming 3-bedroom, 2.5 bath townhome. Largest with accommodations in Florence.
10.0 out of 10, Exceptional, (9 reviews)
"Great place beautiful and the dogs loved it"
United States
Jennifer T.
The price is CA $305
CA $592 total
includes taxes & fees
Mar 9 - Mar 10
Creekside Country Cottage- minutes away from I-95
The price is CA $204
CA $346 total
includes taxes & fees
Mar 14 - Mar 15
Charming 1-bedroom house with WiFi, AC in nice Sumter
8.0 out of 10, Very good, (1 review)
"The stay was fine , with no problems."
United States
Mark H.
The price is CA $92
CA $203 total
includes taxes & fees
Mar 15 - Mar 16
Lakeside 2-bedroom RV in charming Hartsville with AC, WiFi
10.0 out of 10, Exceptional, (47 reviews)
"I would definitely stay again! Great location."
United States
LaDara D.
The price is CA $309
CA $395 total
includes taxes & fees
Mar 9 - Mar 10
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
8.0 out of 10, Very good, (1 review)
"we did not see or talk directly to the host; the amenities were all in good condition"
United States
George H.
The price is CA $121
CA $188 total
includes taxes & fees
Apr 5 - Apr 6
Cozy 1-bedroom apartment at Greenleaf Villa. Downtown Camden, SC.
9.8 out of 10, Exceptional, (6 reviews)
The price is CA $291
CA $371 total
includes taxes & fees
Mar 15 - Mar 16
Perfect Stop • Near I-95, Downtown & Civic Center and Darlington

Vacation Home in Sumter

The Farm House on Adams
The price is CA $244
CA $482 total
includes taxes & fees
Mar 31 - Apr 1
The Farm House on Adams
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Top Lee County Hotel Reviews

Find out more about Lee County

Everything you need to know about Lee County vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Lee County vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Lee County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Lee County vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Lee County. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Lee County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Lee County vacation rentals we have selected for you start as low as CA $188 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Lee County rentals

At Expedia, we put the best Lee County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Lee County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Lee County vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Lee County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.