Find hotels in Jefferson, SC from CA $79

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Go beyond your typical stay in Jefferson

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Check prices for these dates

Tonight
Nov 11 - Nov 12
Tomorrow
Nov 12 - Nov 13
This weekend
Nov 13 - Nov 15
Next weekend
Nov 20 - Nov 22

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Our top choices for Jefferson hotels

A Holiday Inn Express & Suites hotel with a stone facade and blue lighting.

1. Holiday Inn Express & Suites Monroe by IHG

Holiday Inn Express & Suites Monroe by IHG
2.5 star property
Monroe
9.4 out of 10, Exceptional, (1,001 reviews)
"Was great"
United States
ROSALIA
The price is CA $161
CA $180 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express & Suites Monroe by IHG
A breakfast buffet with various baked goods and cereals.

2. Quality Inn & Suites Monroe

Quality Inn & Suites Monroe
2.5 star property
Monroe
7.2 out of 10, Good, (679 reviews)
"Everything good, staff, parking, breakfast and clean room."
United States
odali
The price is CA $80
CA $89 total
includes taxes & fees
Dec 6 - Dec 7
Quality Inn & Suites Monroe
A modern building entrance with a wooden ceiling, glass doors, and a brick facade.

3. Hampton Inn Charlotte/Monroe

Hampton Inn Charlotte/Monroe
2.5 star property
Monroe
8.8 out of 10, Excellent, (1,000 reviews)
"Went there for a wedding. Hotel was convenient and perfect for our needs. We would stay there again."
United States
Michael
The price is CA $161
CA $180 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn Charlotte/Monroe
A restaurant with a bar, wooden panel walls, and a TV mounted on the wall.

4. Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
3.0 star property
Hartsville
8.4 out of 10, Very good, (807 reviews)
"Clean room, excellent breakfast, staff were very friendly and welcoming."
United States
Jessica
The price is CA $151
CA $169 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn by Marriott Hartsville
A multi-story Fairfield by Marriott Inn & Suites building with a modern design, featuring a prominent entrance and a parking lot.

5. Fairfield Inn & Suites by Marriott Charlotte Monroe

Fairfield Inn & Suites by Marriott Charlotte Monroe
3.0 star property
Monroe
9.2 out of 10, Wonderful, (368 reviews)
"firepit"
United States
Christine
The price is CA $155
CA $173 total
includes taxes & fees
Nov 22 - Nov 23
Fairfield Inn & Suites by Marriott Charlotte Monroe
A hotel lobby with a sofa, coffee table, and potted plants. There is a kitchen area with a dining table and chairs. A clock and television are mounted on the wall.

6. Best Western Inn & Suites - Monroe

Best Western Inn & Suites - Monroe
2.5 star property
Monroe
8.6 out of 10, Excellent, (583 reviews)
"Great staff, nice clean rooms"
United States
Meredith
The price is CA $152
CA $170 total
includes taxes & fees
Nov 15 - Nov 16
Best Western Inn & Suites - Monroe
A spacious restaurant with high ceilings, hanging crystal chandeliers, and a variety of seating options including tables and booths.

7. Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
2.5 star property
Hartsville
9.2 out of 10, Wonderful, (528 reviews)
"Superb staff, amenities and food"
Canada
Kaustubh
The price is CA $167
CA $187 total
includes taxes & fees
Dec 11 - Dec 12
Hampton Inn & Suites Hartsville
An outdoor patio with wicker furniture, a fire feature, and string lights.

8. The Mantissa Hotel

The Mantissa Hotel
3.0 star property
Hartsville
9.2 out of 10, Wonderful, (318 reviews)
"We stayed for a wedding. The location is close to restaurants and local shops. Our room was spacious and the staff is friendly. We really enjoyed the rooftop bar!"
United States
Ricki
The price is CA $229
CA $256 total
includes taxes & fees
Nov 18 - Nov 19
The Mantissa Hotel
A hotel room with a large bed, a desk with a TV, a chair, and a window with curtains.

9. Red Roof Inn & Suites Monroe, NC

Red Roof Inn & Suites Monroe, NC
2.0 star property
Monroe
6.4 out of 10, (294 reviews)
"Quick check in and out !"
United States
Richard
The price is CA $81
CA $90 total
includes taxes & fees
Nov 15 - Nov 16
Red Roof Inn & Suites Monroe, NC
A cafe with a glass enclosure, white cabinets, and red chairs.

10. Super 8 by Wyndham Lancaster

Super 8 by Wyndham Lancaster
2.0 star property
Lancaster
7.2 out of 10, Good, (486 reviews)
"Inexpensive, good location, perfect for a one night stay in the Lancaster area"
United States
david
The price is CA $84
CA $94 total
includes taxes & fees
Dec 4 - Dec 5
Super 8 by Wyndham Lancaster
A hotel room with a bed, a desk, a chair, a sofa, and a small table.

11. Americas Best Value Inn Wadesboro

Americas Best Value Inn Wadesboro
2.0 star property
Wadesboro
8.0 out of 10, Very good, (141 reviews)
"Place was clean and comfortable. It was a pleasure to stay there"
United States
Fred
The price is CA $140
CA $159 total
includes taxes & fees
Nov 12 - Nov 13
Americas Best Value Inn Wadesboro
A hotel room with a large bed, a nightstand, a wall-mounted lamp, and a cityscape painting above the bed.

12. Days Inn by Wyndham Monroe NC

Days Inn by Wyndham Monroe NC
1.5 star property
Monroe
6.6 out of 10, (106 reviews)
"Front desk staff was very helpful. This is a decent place to stay that is less expensive than some of the other options in Monroe. Will plan to stay here again."
United States
Margaret
The price is CA $99
CA $110 total
includes taxes & fees
Nov 15 - Nov 16
Days Inn by Wyndham Monroe NC
A modern lobby with black leather sofas, white tables, and lamps. Large windows offer views of parked cars and trees.

13. The Landmark Inn

The Landmark Inn
2.5 star property
Hartsville
7.0 out of 10, Good, (350 reviews)
"Rooms are very nice and clean for the price"
United States
Brittney
The price is CA $120
CA $139 total
includes taxes & fees
Nov 12 - Nov 13
The Landmark Inn
A room with a wooden floor, a black table, a reception desk, a clock, and a door with a sign.

14. Colony Inn

Colony Inn
2.5 star property
Camden
6.2 out of 10, (372 reviews)
"The property is old and poorly maintained"
United States
Jaime
The price is CA $85
CA $95 total
includes taxes & fees
Dec 2 - Dec 3
Colony Inn
A hotel with a row of rooms, a parking lot, and a view of the Milky Way.

15. Rodeway Inn Monroe

Rodeway Inn Monroe
2.0 star property
Monroe
5.6 out of 10, (261 reviews)
"Other than the fact that my room was missing an ice bucket, my experience went well."
United States
Patrick
The price is CA $85
CA $94 total
includes taxes & fees
Nov 13 - Nov 14
Rodeway Inn Monroe
A spacious lobby with a wooden floor, a reception desk, a large mirror, and a potted plant.

16. Quality Inn Lancaster

Quality Inn Lancaster
2.5 star property
Lancaster
7.4 out of 10, Good, (355 reviews)
"the room was clean and neat. I rested well. The free breakfast was a little disappointing, but I was able to get some toast and yogurt."
United States
Daniel
The price is CA $113
CA $127 total
includes taxes & fees
Dec 4 - Dec 5
Quality Inn Lancaster
A hotel lobby with a reception desk, a white armchair, a vase of flowers, a black table, a brick wall, and a kitchen area with appliances.

17. Quality Inn Hartsville

Quality Inn Hartsville
2.5 star property
Hartsville
6.0 out of 10, (357 reviews)
"I enjoy my stay everything was so convenient. I wouldn't change a thing"
United States
Christopher
The price is CA $99
CA $112 total
includes taxes & fees
Dec 1 - Dec 2
Quality Inn Hartsville
A two-story house with a front porch, a stone foundation, and a well-maintained lawn.

18. PRIVATE one bed, one bath and separate entrance at Revolving Door Ranch

PRIVATE one bed, one bath and separate entrance at Revolving Door Ranch
Camden
9.2 out of 10, Wonderful, (36 reviews)
"Perfect!"
United States
Pam J.
The price is CA $89
CA $150 total
includes taxes & fees
Nov 12 - Nov 13
PRIVATE one bed, one bath and separate entrance at Revolving Door Ranch
A hotel room with two beds, a desk, a chair, a desk lamp, a mirror, and a wall-mounted air conditioning unit.

19. Super 8 by Wyndham Monroe

Super 8 by Wyndham Monroe
2.0 star property
Monroe
5.4 out of 10, (394 reviews)
"5 star⭐️⭐️⭐️⭐️⭐️"
United States
Charlotte
The price is CA $104
CA $117 total
includes taxes & fees
Nov 19 - Nov 20
Super 8 by Wyndham Monroe
A hotel room with a dining table, chairs, a television, and a view of a lawn through large windows.

20. Executive Inn Kershaw

Executive Inn Kershaw
Kershaw
7.6 out of 10, Good, (5 reviews)
"Place looks better in your photo than in real life. You need to touch up the real life so it can match the photo."
United States
Peter
The price is CA $85
CA $95 total
includes taxes & fees
Nov 12 - Nov 13
Executive Inn Kershaw
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Jefferson Hotel Reviews

A spacious restaurant with high ceilings, hanging crystal chandeliers, and a variety of seating options including tables and booths.
Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville

Hampton Inn & Suites Hartsville
Hartsville

10/10 Excellent

Superb staff, amenities and food
Canada
Kaustubh
Reviewed November 8, 2026
Hampton Inn & Suites Hartsville

Frequently Asked Questions

What is the best area to stay in Jefferson?

The best area to stay in Jefferson is the town centre, particularly around Main Street.

This area is the heart of Jefferson, offering a convenient base for exploring. Main Street is where you'll find most of the local shops, eateries, and community services. It's a compact and walkable area, making it easy to access everything Jefferson has to offer.

Couples looking for a relaxing and uncomplicated getaway will find the town centre ideal. With local restaurants and cafes within easy walking distance, you can enjoy quiet evenings without needing to travel far. The proximity to local parks also offers opportunities for leisurely strolls.

For solo travellers, the town centre provides a friendly and accessible environment.

When is the best time to go to Jefferson?

The best time to go to Jefferson, South Carolina, is during the spring (April to May) and autumn (September to October) months.

During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity, making it ideal for exploring the outdoors and enjoying local events. Spring brings blooming flowers and a refreshing atmosphere, while autumn offers colourful foliage and crisp air.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Jefferson.

How much is the nightly rate at a Jefferson hotel?

Prices for hotels in Jefferson often vary, but you can find a great deal from CA $79 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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