Isla Grande Vacation Rentals

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Our top choices for Isla Grande vacation rentals

Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province
Colón Province
The price is CA $464
CA $528 total
includes taxes & fees
May 11 - May 12
Deluxe Beachfront 4-bedroom house in Colón Province

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking
Puerto Lindo
The price is CA $308
CA $342 total
includes taxes & fees
May 12 - May 13
Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

San Marino Duo, this is casa 36 - Book one or both separatly 36 &/or 37.

San Marino Duo, this is casa 36 - Book one or both separatly 36 &/or 37.
Guanche - Colon - Panama
9.0 out of 10, Wonderful, (4 reviews)
"My small party (myself, my husband, our friend & our 14 yr old son) stayed in Casa #37 for 3 nights during President's Week while exploring the area. The home is VERY spacious, well-equipped, a short drive to Portobelo and close to many recreational activities. It's perfect for those who want to be as close to the ocean as humanly possibly and surrounded by natural beauty. Bob & Maria were enthusiastic, responsive & hospitable hosts (they happened to be in casa #36 at the same time): they...
United States
jen g.
The price is CA $403
CA $630 total
includes taxes & fees
Jun 1 - Jun 2
San Marino Duo, this is casa 36 - Book one or both separatly 36 &/or 37.

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Portobelo
7.0 out of 10, Good, (4 reviews)
"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"
United States
Rosa M.
The price is CA $214
CA $243 total
includes taxes & fees
May 16 - May 17
BEAUTIFUL APARTMENT IN FRONT OF THE SEA

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita
Maria Chiquita
6.6 out of 10, (4 reviews)
"Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!"
United States
Will
The price is CA $146
CA $222 total
includes taxes & fees
May 21 - May 22
Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita

Despierta sobre el mar

Despierta sobre el mar
Garrote
6.0 out of 10, (1 review)
The price is CA $103
CA $147 total
includes taxes & fees
May 12 - May 13
Despierta sobre el mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Grande Hotel Reviews

Find out more about Isla Grande

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Isla Grande. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Isla Grande?

Yes, we have vacation rentals near top sights in Isla Grande, or you can select a more secluded option if you'd like a relaxing place to stay. Isla Grande is known for its parks.

What are some of the best vacation home rentals in Isla Grande?

Deluxe Beachfront 4-bedroom house in Colón Province: This Isla Grande vacation home rental has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Isla Grande?

With 4 Expedia vacation rentals, you're sure to find just the right place for your Isla Grande stay.

What can I see and do in Isla Grande?

While you're exploring the area, Isla Mamey and Blanca Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Portobelo National Park and Fuerte San Fernando.

What are vacation rentals like in Isla Grande?

Vacation rentals are private properties you can stay in for several days or more in Isla Grande. Vacation rentals offer extras such as laundry facilities and kitchens so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family gatherings.