Title: Visit Santo Spirito: Best of Santo Spirito, Florence Travel 2025 | Expedia Tourism - Expedia.ca [Hotels in Santo Spirito](https://expedia.ca/Santo-Spirito-Florence-Hotels.0-n553248633938935375-0.Travel-Guide-Filter-Hotels)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1222.Travel-Guide-Flights)[Things to do in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)[Santo Spirito Car Rentals](https://expedia.ca/Car-Rentals-In-Santo-Spirito.d553248633938935375.Car-Rental-Guide)[Santo Spirito Vacations](https://expedia.ca/Santo-Spirito.d553248633938935375.Destination-Travel-Guides) # Santo Spirito ## Florence ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409791-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409789-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409407-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santo Spirito Things to do Hotels Where to stay [Florence travel guide](https://expedia.ca/Florence.dx1222) * * * ### Popular places to visit ![Piazza Santo Spirito](https://mediaim.expedia.com/destination/9/44b21491ec820fe5ef00b557ca71ac5d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza Santo Spirito Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area. [](https://expedia.ca/Piazza-Santo-Spirito-Florence.d6265853.Vacation-Attraction) ![Porta Romana](https://mediaim.expedia.com/destination/9/a02bf64b639fa2ffea10344e9452a522.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Porta Romana Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums. [](https://expedia.ca/Porta-Romana-Florence.d501037.Vacation-Attraction) ![Brancacci Chapel](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Brancacci Chapel A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine. [](https://expedia.ca/Brancacci-Chapel-Florence.d6143202.Vacation-Attraction) #### Santo Spirito Basilica Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area. [](https://expedia.ca/Santo-Spirito-Basilica-Florence.d6075452.Vacation-Attraction) #### Santa Maria della Carmine You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area. [](https://expedia.ca/Santa-Maria-Della-Carmine-Florence.d6075450.Vacation-Attraction) #### Piazza del Carmine You can learn about the history of Florence with a stop at Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art scene. [](https://expedia.ca/Piazza-Del-Carmine-Florence.d6265851.Vacation-Attraction) ### Things to do ![Florence Accademia Gallery Tour with Entrance Ticket Included](https://mediaim.expedia.com/localexpert/3066485/d26c5e31-1f44-4056-bdee-2fc35c6c6ffc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Accademia Gallery Tour with Entrance Ticket Included CA $62 per adult **90%** of travellers recommend [](https://expedia.ca/things-to-do/florence-accademia-gallery-tour-with-entrance-ticket-included.a3066485.activity-details) ![Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour](https://mediaim.expedia.com/localexpert/507532/cbdef260-9919-420e-a482-1d2f9b3d6ccc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour CA $34 per adult **78%** of travellers recommend [](https://expedia.ca/things-to-do/skip-the-line-florence-duomo-priority-access-express-guided-tour.a507532.activity-details) ![The Best tour in Florence: Renaissance and Medici Tales](https://mediaim.expedia.com/localexpert/2478646/d3fc5c1c-939d-452e-a191-72c31e99cc31.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### The Best Tour in Florence: Renaissance and Medici Tales CA $5 per adult **96%** of travellers recommend [](https://expedia.ca/things-to-do/the-best-tour-in-florence-renaissance-and-medici-tales.a2478646.activity-details) ![Michaelangelo's David](https://mediaim.expedia.com/localexpert/519701/f78b6d6b-180c-4d4e-9a65-4adffb29c139.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Accademia timed-entry Ticket with Instant Delivery & Priority Access CA $47 per adult **88%** of travellers recommend [](https://expedia.ca/things-to-do/accademia-timed-entry-ticket-with-instant-delivery-priority-access.a519701.activity-details) ![Best of Florence Walking Tour](https://mediaim.expedia.com/localexpert/970108/bee6bf2e-9905-40b1-a7e6-463e79154a77.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Best of Florence Walking Tour CA $32 per adult **80%** of travellers recommend [](https://expedia.ca/things-to-do/best-of-florence-walking-tour.a970108.activity-details) ![Brunelleschi's Dome and Cathedral Complex Reserved Ticket](https://mediaim.expedia.com/localexpert/46349018/da6602cd-2dfb-4c7a-9a98-6a5b3e34cdb9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Brunelleschi's Dome and Cathedral Complex Reserved Ticket CA $128 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/brunelleschis-dome-and-cathedral-complex-reserved-ticket.a46349018.activity-details) [See all activities in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities) * * * ## Santo Spirito Hotel Deals ![Hotel Horto Convento](https://images.trvl-media.com/lodging/18000000/17940000/17933900/17933824/9c90a529_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Horto Convento Viale Ariosto, 13, Florence, FI CA $146 CA $184 total Dec 1 - Dec 2 includes taxes & fees Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ... 9.6/10 Exceptional! (584 reviews) An oasis of calm - it is not buzzy and over the top like many places in the tourist center. Instead, it is tranquil, in a good area within easy walking distance to most of what you want to see. We enjoyed our stay. Reviewed on Oct 25, 2025 [](https://expedia.ca/Hotel-Search?startDate=01%2F12%2F2025&endDate=02%2F12%2F2025&selected=17933824&PinnedHotelID=17933824&HadPinnedHotel=true®ionId=553248633938935375) ![UNA Hotels Vittoria Firenze](https://images.trvl-media.com/lodging/1000000/910000/905700/905634/534e501f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### UNA Hotels Vittoria Firenze Via Pisana 59, Florence, FI Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ... 8.4/10 Very Good! (988 reviews) Amazing place, love the decor! Reviewed on Jul 28, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true®ionId=553248633938935375) ![Palazzo Mannaioni Suites](https://images.trvl-media.com/lodging/3000000/2530000/2524400/2524373/5017fcc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Palazzo Mannaioni Suites Via Maffia 9 - 17r, Florence, FI Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ... 9.2/10 Wonderful! (1,042 reviews) The place was clean and located in the heart Florence most memorable attractions.. Reviewed on Oct 29, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) ![La Torre Del Cestello](https://images.trvl-media.com/lodging/12000000/11930000/11925300/11925245/b6c3d47f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Torre Del Cestello Via Borgo San Frediano, 8, Florence, FI CA $126 CA $161 total Dec 1 - Dec 2 includes taxes & fees Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ... 9/10 Wonderful! (217 reviews) I had an amazing stay! My room was great - spacious and clean - and the view from my room was incredible! I also found it to be in a great location - the walk from the train station was easy, and it’s close to the main attractions while also being far enough away to be a little quiet. I’d easily ... Reviewed on Oct 15, 2025 [](https://expedia.ca/Hotel-Search?startDate=01%2F12%2F2025&endDate=02%2F12%2F2025&selected=11925245&PinnedHotelID=11925245&HadPinnedHotel=true®ionId=553248633938935375) ![Hostel Santa Monaca](https://images.trvl-media.com/lodging/21000000/20240000/20230600/20230544/9a22558a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hostel Santa Monaca Via Santa Monaca 6, Florence, FI Stay at this hostel in Florence. Enjoy free WiFi, daily housekeeping, and dry cleaning or laundry services. Popular attractions Ponte Vecchio and Uffizi Gallery ... 8/10 Very Good! (60 reviews) Clean room , friendly staffs & very accessible to any amenities . Separate toilet , shower & lavatory specific for women only , away from male rooms & toilets . Have ample space for kitchen with utensils, tables & chairs . Highly recommended ! Love it Reviewed on Sep 18, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=20230544&PinnedHotelID=20230544&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=20230544&PinnedHotelID=20230544&HadPinnedHotel=true®ionId=553248633938935375) ![Foresteria Valdese di Firenze - Casa per Ferie](https://images.trvl-media.com/lodging/45000000/44160000/44152000/44151975/be607b19_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Foresteria Valdese di Firenze - Casa per Ferie Via dei Serragli 49, Florence, FI Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ... 8.6/10 Excellent! (188 reviews) Very nice and interesting hotel located in Oltrarno, the artsy, lively area of Florence center, but a few blocks away from the crowds. Location is excellent! The hotel is quiet and has a wonderful history. I would stay there again. Reviewed on Oct 21, 2025 [Get rates](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=44151975&PinnedHotelID=44151975&HadPinnedHotel=true®ionId=553248633938935375) [](https://expedia.ca/Hotel-Search?startDate=14%2F11%2F2025&endDate=15%2F11%2F2025&selected=44151975&PinnedHotelID=44151975&HadPinnedHotel=true®ionId=553248633938935375) [See all 474 properties in Santo Spirito](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=01%2F11%2F2025&endDate=02%2F11%2F2025®ionId=553248633938935375) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santo Spirito hotel availability [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-31&endDate=2025-11-01) [Tonight](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-31&endDate=2025-11-01) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-31&endDate=2025-11-01) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-31&endDate=2025-11-01)[Oct 31 - Nov 1](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-31&endDate=2025-11-01) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-11-01&endDate=2025-10-02) [Tomorrow night](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-11-01&endDate=2025-10-02) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-11-01&endDate=2025-10-02) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-11-01&endDate=2025-10-02)[Nov 1 - Nov 2](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-11-01&endDate=2025-10-02) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [This weekend](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025)[Oct 31 - Nov 2](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=31%2F10%2F2025&endDate=02%2F11%2F2025) * * * ### Other neighbourhoods around Santo Spirito ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Frediano San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica. [](https://expedia.ca/Florence-San-Frediano.dx6141947) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408952-Italy.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oltrarno 4.5/5(77 area reviews) South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo. [](https://expedia.ca/Florence-Oltrarno.dx6084345) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410264-Santa-Maria-Novella.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Santa Maria Novella 4.5/5(225 area reviews) Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato. [](https://expedia.ca/Florence-Santa-Maria-Novella.dx6084343) ![Uffizi Gallery featuring street scenes as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31661-Uffizi-Gallery-Galleria-Degli-Uffizi.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Giovanni If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing. [](https://expedia.ca/Florence-San-Giovanni.dx553248635976383065) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410270-Duomo-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Duomo 5/5(339 area reviews) Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops. [](https://expedia.ca/Florence-Duomo.dx6084346) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408985-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Centre of Florence Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city. [](https://expedia.ca/Florence-Historic-Centre-Of-Florence.dx6141938) * * * * * * - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Santo Spirito ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [4 Star Hotels in Florence](https://www.expedia.ca/4Star-Florence-Hotels.s40-0-d1222.Travel-Guide-Filter-Hotels) - [Hotels near Boboli Gardens](https://www.expedia.ca/Boboli-Gardens-Hotels.0-l507684-0.Travel-Guide-Filter-Hotels) - [Winery Hotels in Province of Florence](https://www.expedia.ca/Destinations-In-Province-Of-Florence-Winery-Hotel.0-0-d179893-tWineryHotel.Hotel-Filter-Destinations) - [Province of Florence Hotels](https://www.expedia.ca/Destinations-In-Province-Of-Florence.d179893.Hotel-Destinations) - [All Inclusive Resorts and in Tuscany](https://www.expedia.ca/Destinations-In-Tuscany-All-Inclusive-Hotel.0-0-d601686-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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