Title: Visit Santo Spirito: Best of Santo Spirito, Florence Travel 2026 | Expedia Tourism - Expedia.ca

[Hotels in Santo Spirito](https://expedia.ca/Santo-Spirito-Florence-Hotels.0-n553248633938935375-0.Travel-Guide-Filter-Hotels)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1222.Travel-Guide-Flights)[Things to do in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)[Santo Spirito Car Rentals](https://expedia.ca/Car-Rentals-In-Santo-Spirito.d553248633938935375.Car-Rental-Guide)[Santo Spirito Vacations](https://expedia.ca/Santo-Spirito.d553248633938935375.Destination-Travel-Guides)

# Santo Spirito

## Florence

![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409791-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409789-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409407-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh)

## Visit Santo Spirito

Things to do

Hotels

Where to stay

[Florence travel guide](https://expedia.ca/Florence.dx1222)

---

### Popular places to visit

![Piazza Santo Spirito](https://mediaim.expedia.com/destination/9/44b21491ec820fe5ef00b557ca71ac5d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Piazza Santo Spirito

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and churches in this vibrant area. 

[](https://expedia.ca/Piazza-Santo-Spirito-Florence.d6265853.Vacation-Attraction)

![Porta Romana](https://mediaim.expedia.com/destination/9/a02bf64b639fa2ffea10344e9452a522.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Porta Romana

Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums. 

[](https://expedia.ca/Porta-Romana-Florence.d501037.Vacation-Attraction)

![Brancacci Chapel](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Brancacci Chapel

A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.

[](https://expedia.ca/Brancacci-Chapel-Florence.d6143202.Vacation-Attraction)

#### Santo Spirito Basilica

Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area. 

[](https://expedia.ca/Santo-Spirito-Basilica-Florence.d6075452.Vacation-Attraction)

#### Torrigiani Garden

Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area. 

[](https://expedia.ca/Torrigiani-Garden-Florence.d553248621532498389.Vacation-Attraction)

#### Santa Maria della Carmine

You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area. 

[](https://expedia.ca/Santa-Maria-Della-Carmine-Florence.d6075450.Vacation-Attraction)

### Things to do

![Florence Accademia Gallery Tour with Entrance Ticket Included](https://mediaim.expedia.com/localexpert/3066485/d26c5e31-1f44-4056-bdee-2fc35c6c6ffc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Florence Accademia Gallery Tour with Entrance Ticket Included

CA $61

per adult

**92%** of travellers recommend

[](https://expedia.ca/things-to-do/florence-accademia-gallery-tour-with-entrance-ticket-included.a3066485.activity-details)

![Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour](https://mediaim.expedia.com/localexpert/507532/cbdef260-9919-420e-a482-1d2f9b3d6ccc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

CA $37

per adult

**80%** of travellers recommend

[](https://expedia.ca/things-to-do/skip-the-line-florence-duomo-priority-access-express-guided-tour.a507532.activity-details)

![Pisa and Piazza dei Miracoli Half Day Tour from Florence](https://mediaim.expedia.com/localexpert/558114/ee5005a3-7dc7-4d52-b37b-cb457ae399b1.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Pisa and Piazza dei Miracoli Half Day Tour from Florence

CA $50

per adult

**88%** of travellers recommend

[](https://expedia.ca/things-to-do/pisa-and-piazza-dei-miracoli-half-day-tour-from-florence.a558114.activity-details)

![Best of Florence Walking Tour](https://mediaim.expedia.com/localexpert/970108/bee6bf2e-9905-40b1-a7e6-463e79154a77.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Best of Florence Walking Tour

CA $32

per adult

**80%** of travellers recommend

[](https://expedia.ca/things-to-do/best-of-florence-walking-tour.a970108.activity-details)

![Florence half day combo tour with David, Uffizi & Duomo](https://mediaim.expedia.com/localexpert/177530/67736287-bdb2-4b4e-a2f9-65e0ac592e0e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia

CA $46

per adult

**92%** of travellers recommend

[](https://expedia.ca/things-to-do/florence-half-day-tour-with-uffizi.a177530.activity-details)

![E-bike Adventure To Fiesole From Florence With Olive Oil Tasting ](https://mediaim.expedia.com/localexpert/50213153/96a9d29f-9bc7-42c6-8c71-8acd22ca8590.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### E-bike Adventure To Fiesole From Florence With Olive Oil Tasting

CA $40

per adult

**100%** of travellers recommend

[](https://expedia.ca/things-to-do/e-bike-adventure-to-fiesole-from-florence-with-olive-oil-tasting.a50213153.activity-details)

[See all activities in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)

---

## Santo Spirito Hotel Deals

![Hotel Horto Convento](https://images.trvl-media.com/lodging/18000000/17940000/17933900/17933824/9c90a529_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hotel Horto Convento

Viale Ariosto, 13 Florence FI

CA $166

CA $206 total

Jan 23 - Jan 24, 2026

includes taxes & fees

Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...

9.6/10 Exceptional! (603 reviews)

The hotel is very nice and well located, you can reach the tourist spots in Florence by walking. The staff is helpful and friendly, and the rooms are comfortable.

Reviewed on Dec 21, 2025

[](https://expedia.ca/Hotel-Search?startDate=23%2F01%2F2026&endDate=24%2F01%2F2026&selected=17933824&PinnedHotelID=17933824&HadPinnedHotel=true&regionId=553248633938935375)

![Palazzo Mannaioni Suites](https://images.trvl-media.com/lodging/3000000/2530000/2524400/2524373/5017fcc9_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Palazzo Mannaioni Suites

Via Maffia 9 - 17r Florence FI

CA $170

CA $210 total

Jan 11 - Jan 12, 2026

includes taxes & fees

Stay at this residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. Popular ...

9.2/10 Wonderful! (1,057 reviews)

The room was clean the day we got in, the next days they didn’t enter to clean it and the rules where to leave clean the kitchen, if not, they would charge 50 euros

Reviewed on Dec 12, 2025

[](https://expedia.ca/Hotel-Search?startDate=11%2F01%2F2026&endDate=12%2F01%2F2026&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true&regionId=553248633938935375)

![La Torre Del Cestello](https://images.trvl-media.com/lodging/12000000/11930000/11925300/11925245/b6c3d47f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI

CA $129

CA $165 total

Jan 22 - Jan 23, 2026

includes taxes & fees

Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are ...

9/10 Wonderful! (228 reviews)

Very impressive! We received the notifications few days before arrival to remind us about the date and time. Check-in process was quick and easy, service was great. The staffs were very friendly. Room was large, nice and clean. They kept cleaning daily. Great location and walkable to several attractions ...

Reviewed on Dec 13, 2025

[](https://expedia.ca/Hotel-Search?startDate=22%2F01%2F2026&endDate=23%2F01%2F2026&selected=11925245&PinnedHotelID=11925245&HadPinnedHotel=true&regionId=553248633938935375)

![UNA Hotels Vittoria Firenze](https://images.trvl-media.com/lodging/1000000/910000/905700/905634/534e501f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

UNA Hotels Vittoria Firenze

Via Pisana 59 Florence FI

Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...

8.4/10 Very Good! (987 reviews)

Super nice reception staffs, everyone is so friendly and welcoming. But don’t like the red room decoration.

Reviewed on Nov 5, 2025

[Get rates](https://expedia.ca/Hotel-Search?startDate=06%2F01%2F2026&endDate=07%2F01%2F2026&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true&regionId=553248633938935375)

[](https://expedia.ca/Hotel-Search?startDate=06%2F01%2F2026&endDate=07%2F01%2F2026&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true&regionId=553248633938935375)

![Oltrarno Splendid](https://images.trvl-media.com/lodging/36000000/35630000/35625200/35625179/23b1bfc3_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Oltrarno Splendid

Via dei Serragli 7 Florence FI

CA $213

CA $257 total

Jan 19 - Jan 20, 2026

includes taxes & fees

Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular attractions ...

9.8/10 Exceptional! (97 reviews)

Fabulous place to stay

Reviewed on Dec 7, 2025

[](https://expedia.ca/Hotel-Search?startDate=19%2F01%2F2026&endDate=20%2F01%2F2026&selected=35625179&PinnedHotelID=35625179&HadPinnedHotel=true&regionId=553248633938935375)

![La Fonderia Firenze](https://images.trvl-media.com/lodging/20000000/19550000/19544000/19543964/94838c37_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

La Fonderia Firenze

Via della Fonderia 65/A Florence FI

CA $135

CA $168 total

Dec 25 - Dec 26

includes taxes & fees

Stay at this B&B in Florence. Enjoy free breakfast, free WiFi, and a garden. Our guests praise the breakfast and the helpful staff in our reviews. Popular attractions ...

9.4/10 Exceptional! (172 reviews)

The single room is in the attic upstairs, small but clean and sufficient. The bathroom is private for the guest, located just outside the room, and is clean and spacious. The staff is very friendly. The location is a bit far from the city center, but not excessively. Highly recommended.

Reviewed on Oct 17, 2025

[](https://expedia.ca/Hotel-Search?startDate=25%2F12%2F2025&endDate=26%2F12%2F2025&selected=19543964&PinnedHotelID=19543964&HadPinnedHotel=true&regionId=553248633938935375)

[See all 488 properties in Santo Spirito](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=24%2F12%2F2025&endDate=25%2F12%2F2025&regionId=553248633938935375)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Check Santo Spirito hotel availability

[Tonight

](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=2025-12-23&endDate=2025-12-24)[Dec 23 - Dec 24](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=2025-12-23&endDate=2025-12-24)

[Tomorrow night

](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=2025-12-24&endDate=2025-12-25)[Dec 24 - Dec 25](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=2025-12-24&endDate=2025-12-25)

[This weekend

](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)[Dec 26 - Dec 28](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=26%2F12%2F2025&endDate=28%2F12%2F2025)

[Next weekend

](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026)[Jan 2 - Jan 4](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=553248633938935375&startDate=02%2F01%2F2026&endDate=04%2F01%2F2026)

---

### Other neighbourhoods around Santo Spirito

![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Frediano

 San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Boboli Gardens. 

[](https://expedia.ca/Florence-San-Frediano.dx6141947)

![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408952-Italy.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Oltrarno

4.5/5(77 area reviews)

 South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo. 

[](https://expedia.ca/Florence-Oltrarno.dx6084345)

![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410264-Santa-Maria-Novella.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Santa Maria Novella

4.5/5(225 area reviews)

 Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato. 

[](https://expedia.ca/Florence-Santa-Maria-Novella.dx6084343)

![Uffizi Gallery featuring street scenes as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31661-Uffizi-Gallery-Galleria-Degli-Uffizi.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### San Giovanni

 If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing. 

[](https://expedia.ca/Florence-San-Giovanni.dx553248635976383065)

![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408985-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Historic Centre of Florence

 Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city. 

[](https://expedia.ca/Florence-Historic-Centre-Of-Florence.dx6141938)

![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410270-Duomo-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium)

### Duomo

5/5(339 area reviews)

 Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops. 

[](https://expedia.ca/Florence-Duomo.dx6084346)

---

---

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- [San Giovanni Hotels ](https://www.expedia.ca/San-Giovanni-Florence-Hotels.0-n553248635976383065-0.Travel-Guide-Filter-Hotels)
- [Cheap Hotels in Santa Maria Novella ](https://www.expedia.ca/Santa-Maria-Novella-Florence-Hotels-Cheap-Hotels.0-n6084343-0-tCheapHotels.Travel-Guide-Filter-Hotels)
- [Santa Maria Novella Hotels ](https://www.expedia.ca/Santa-Maria-Novella-Florence-Hotels.0-n6084343-0.Travel-Guide-Filter-Hotels)
- [Hotels near Santa Trinita Church ](https://www.expedia.ca/Santa-Trinita-Church-Hotels.0-l6075400-0.Travel-Guide-Filter-Hotels)
- [Farmstay in Tuscany ](https://www.expedia.ca/Tuscany-Agritourism.d601686-aaAgritourism.Travel-Guide-Accommodation)
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- [Hotels near Uffizi Gallery ](https://www.expedia.ca/Uffizi-Gallery-Hotels.0-l6075462-0.Travel-Guide-Filter-Hotels)

- [Flights to Florence ](https://www.expedia.ca/Cheap-Flights-To-Florence.d1222.Travel-Guide-Flights)
- [Flights to Tuscany ](https://www.expedia.ca/Destinations-In-Tuscany.d601686.Flight-Destinations)

- [Visit Arcetri ](https://www.expedia.ca/Arcetri.dx6142058)
- [Boboli Gardens ](https://www.expedia.ca/Boboli-Gardens-Oltrarno.d507684.Vacation-Attraction)
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- [Visit Chiocchio ](https://www.expedia.ca/Chiocchio.dx6047589)
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- [Visit Campo di Marte ](https://www.expedia.ca/Florence-Campo-Di-Marte.dx6271876)
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- [Galileo Museum - Institute and Museum of the History of Science ](https://www.expedia.ca/Galileo-Museum-Institute-And-Museum-Of-The-History-Of-Science-Duomo.d6075454.Vacation-Attraction)
- [Visit Galluzzo ](https://www.expedia.ca/Galluzzo.dx179139)
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- [Visit Lungarno del Tempio ](https://www.expedia.ca/Lungarno-Del-Tempio.dx6141944)
- [Visit Poggio alla Malva ](https://www.expedia.ca/Poggio-Alla-Malva.dx6060129)
- [Visit Pontassieve ](https://www.expedia.ca/Pontassieve.dx179126)
- [Visit Ponte a Ema ](https://www.expedia.ca/Ponte-A-Ema.dx6142066)
- [Province of Florence Vacations ](https://www.expedia.ca/Province-Of-Florence.d179893.Destination-Travel-Guides)
- [Visit Province of Florence ](https://www.expedia.ca/Province-Of-Florence.dx179893)
- [Visit San Jacopo Al Girone ](https://www.expedia.ca/San-Jacopo-Al-Girone.dx6251787)
- [Visit Sant'Andrea in Percussina ](https://www.expedia.ca/SantAndrea-In-Percussina.dx3000460952)
- [Visit Sesto Fiorentino ](https://www.expedia.ca/Sesto-Fiorentino.dx179118)
- [Visit Signa ](https://www.expedia.ca/Signa.dx179116)
- [Visit Tavarnuzze ](https://www.expedia.ca/Tavarnuzze.dx6034558)
- [Tuscany Vacations ](https://www.expedia.ca/Tuscany.d601686.Destination-Travel-Guides)
- [Visit Tuscany ](https://www.expedia.ca/Tuscany.dx601686)
- [Uffizi Gallery ](https://www.expedia.ca/Uffizi-Gallery-Duomo.d6075462.Vacation-Attraction)
- [Visit Vallina ](https://www.expedia.ca/Vallina.dx553248635975873008)
- [All inclusive Vacation Packages Tuscany ](https://www.expedia.ca/lp/theme-vacations/all-inclusive-vacations/601686/Tuscany)

- [Car rental Florence ](https://www.expedia.ca/Car-Rentals-In-Florence.d1222.Car-Rental-Guide)
- [Car rentals near Santa Maria Novella ](https://www.expedia.ca/Car-Rentals-In-Santa-Maria-Novella.d6084343.Car-Rental-Guide)
- [Convertible Car Rentals in Province of Florence ](https://www.expedia.ca/Convertible-Car-Rentals-In-Province-Of-Florence.d179893-tConvertible.Car-Rental-Destination-Class)
- [Convertible Car Rentals in Tuscany ](https://www.expedia.ca/Convertible-Car-Rentals-In-Tuscany.d601686-tConvertible.Car-Rental-Destination-Class)
- [Car rentals near Province of Florence ](https://www.expedia.ca/Destinations-In-Province-Of-Florence.d179893.Car-Rental-Destinations)
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- [Van Car Rentals in Tuscany ](https://www.expedia.ca/Van-Car-Rentals-In-Tuscany.d601686-tVan.Car-Rental-Destination-Class)

- [Province of Florence Vacation Rentals ](https://www.expedia.ca/Destinations-In-Province-Of-Florence.d179893.Vacation-Rental-Destinations)
- [Tuscany Vacation Rentals ](https://www.expedia.ca/Destinations-In-Tuscany.d601686.Vacation-Rental-Destinations)

- [Things to do in Florence ](https://www.expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)
- [Things to do in Province of Florence ](https://www.expedia.ca/Things-To-Do-In-Province-Of-Florence.d179893.Travel-Guide-Activities)
- [Things to do in Tuscany ](https://www.expedia.ca/Things-To-Do-In-Tuscany.d601686.Travel-Guide-Activities)

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