Title: Visit Santo Spirito: Best of Santo Spirito, Florence Travel 2025 | Expedia Tourism - Expedia.ca [Hotels in Santo Spirito](https://expedia.ca/Santo-Spirito-Florence-Hotels.0-n553248633938935375-0.Travel-Guide-Filter-Hotels)[Flights to Florence](https://expedia.ca/Cheap-Flights-To-Florence.d1222.Travel-Guide-Flights)[Things to do in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities)[Santo Spirito Car Rentals](https://expedia.ca/Car-Rentals-In-Santo-Spirito.d553248633938935375.Car-Rental-Guide)[Santo Spirito Vacations](https://expedia.ca/Santo-Spirito.d553248633938935375.Destination-Travel-Guides) # Santo Spirito ## Florence ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409791-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409789-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Santo Spirito](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409407-Arcetri.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Santo Spirito Things to do Hotels Where to stay [Florence travel guide](https://expedia.ca/Florence.dx1222) * * * ### Popular places to visit ![Piazza Santo Spirito](https://mediaim.expedia.com/destination/9/44b21491ec820fe5ef00b557ca71ac5d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Piazza Santo Spirito Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area. [](https://expedia.ca/Piazza-Santo-Spirito-Florence.d6265853.Vacation-Attraction) ![Porta Romana](https://mediaim.expedia.com/destination/9/a02bf64b639fa2ffea10344e9452a522.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Porta Romana Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums. [](https://expedia.ca/Porta-Romana-Florence.d501037.Vacation-Attraction) ![Brancacci Chapel](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409396-Arcetri.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Brancacci Chapel A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine. [](https://expedia.ca/Brancacci-Chapel-Florence.d6143202.Vacation-Attraction) #### Santo Spirito Basilica Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area. [](https://expedia.ca/Santo-Spirito-Basilica-Florence.d6075452.Vacation-Attraction) #### Santa Maria della Carmine You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the churches and notable monuments in this vibrant area. [](https://expedia.ca/Santa-Maria-Della-Carmine-Florence.d6075450.Vacation-Attraction) #### Piazza del Carmine You can learn about the history of Florence with a stop at Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art scene. [](https://expedia.ca/Piazza-Del-Carmine-Florence.d6265851.Vacation-Attraction) ### Things to do ![Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour](https://mediaim.expedia.com/localexpert/507532/cbdef260-9919-420e-a482-1d2f9b3d6ccc.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour CA $34 per adult **76%** of travellers recommend [](https://expedia.ca/things-to-do/skip-the-line-florence-duomo-priority-access-express-guided-tour.a507532.activity-details) ![Florence: Reserved Entry Ticket to Bargello Museum](https://mediaim.expedia.com/localexpert/4847727/c59bc38f-7641-4288-b707-dfc13ddc9284.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence: Reserved Entry Ticket to Bargello Museum CA $26 per adult [](https://expedia.ca/things-to-do/florence-reserved-entry-ticket-to-bargello-museum.a4847727.activity-details) ![Florence half day combo tour with David, Uffizi & Duomo](https://mediaim.expedia.com/localexpert/177530/67736287-bdb2-4b4e-a2f9-65e0ac592e0e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia CA $66 per adult **90%** of travellers recommend [](https://expedia.ca/things-to-do/florence-half-day-tour-with-uffizi.a177530.activity-details) ![Cinque Terre: the scent of the sea from Florence](https://mediaim.expedia.com/localexpert/559611/08bdba9b-8a6b-406a-8165-9d2a234fabf4.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Cinque Terre: the scent of the sea from Florence CA $77 per adult [](https://expedia.ca/things-to-do/cinque-terre-the-scent-of-the-sea-from-florence.a559611.activity-details) ![Best of Florence Walking Tour](https://mediaim.expedia.com/localexpert/970108/bee6bf2e-9905-40b1-a7e6-463e79154a77.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Best of Florence Walking Tour CA $33 per adult **100%** of travellers recommend [](https://expedia.ca/things-to-do/best-of-florence-walking-tour.a970108.activity-details) ![Michaelangelo's David](https://mediaim.expedia.com/localexpert/519701/f78b6d6b-180c-4d4e-9a65-4adffb29c139.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Accademia timed-entry Ticket with Instant Delivery & Priority Access CA $47 per adult **88%** of travellers recommend [](https://expedia.ca/things-to-do/accademia-timed-entry-ticket-with-instant-delivery-priority-access.a519701.activity-details) [See all activities in Florence](https://expedia.ca/Things-To-Do-In-Florence.d1222.Travel-Guide-Activities) * * * ## Santo Spirito Hotel Deals ![Hotel Horto Convento](https://images.trvl-media.com/lodging/18000000/17940000/17933900/17933824/9c90a529_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Horto Convento Viale Ariosto, 13, Florence, FI CA $197 CA $240 total Nov 2 - Nov 3 includes taxes & fees Stay at this 4-star hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. ... 9.6/10 Exceptional! (573 reviews) "Excellent location and very helpful staff." Reviewed on Oct 10, 2025 [](https://expedia.ca/Hotel-Search?startDate=02%2F11%2F2025&endDate=03%2F11%2F2025&selected=17933824&PinnedHotelID=17933824&HadPinnedHotel=true®ionId=553248633938935375) ![Palazzo Mannaioni Suites](https://images.trvl-media.com/lodging/3000000/2530000/2524400/2524373/5017fcc9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Palazzo Mannaioni Suites Via Maffia 9 - 17r, Florence, FI CA $204 CA $247 total Nov 2 - Nov 3 includes taxes & fees Stay at this 4-star residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. ... 9.2/10 Wonderful! (1,038 reviews) "Room was very clean and staff extremely friendly. Location was great. Not in the touristy area but not a far walk. Close tk great restaurants. Night time was loud with something unrelated to the hotel outside every night" Reviewed on Oct 12, 2025 [](https://expedia.ca/Hotel-Search?startDate=02%2F11%2F2025&endDate=03%2F11%2F2025&selected=2524373&PinnedHotelID=2524373&HadPinnedHotel=true®ionId=553248633938935375) ![UNA Hotels Vittoria Firenze](https://images.trvl-media.com/lodging/1000000/910000/905700/905634/534e501f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### UNA Hotels Vittoria Firenze Via Pisana 59, Florence, FI CA $142 CA $179 total Nov 6 - Nov 7 includes taxes & fees Stay at this 4-star boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ... 8.4/10 Very Good! (988 reviews) "Amazing place, love the decor!" Reviewed on Jul 28, 2025 [](https://expedia.ca/Hotel-Search?startDate=06%2F11%2F2025&endDate=07%2F11%2F2025&selected=905634&PinnedHotelID=905634&HadPinnedHotel=true®ionId=553248633938935375) ![La Torre Del Cestello](https://images.trvl-media.com/lodging/12000000/11930000/11925300/11925245/b6c3d47f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### La Torre Del Cestello Via Borgo San Frediano, 8, Florence, FI CA $164 CA $200 total Nov 9 - Nov 10 includes taxes & fees Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ... 9/10 Wonderful! (212 reviews) "Lovely" Reviewed on Oct 3, 2025 [](https://expedia.ca/Hotel-Search?startDate=09%2F11%2F2025&endDate=10%2F11%2F2025&selected=11925245&PinnedHotelID=11925245&HadPinnedHotel=true®ionId=553248633938935375) ![Casa Santo Nome di Gesù](https://images.trvl-media.com/lodging/18000000/17910000/17907800/17907720/7a971b8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Casa Santo Nome di Gesù Piazza del Carmine, 21, Florence, FI CA $188 CA $226 total Nov 2 - Nov 3 includes taxes & fees Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ... 8.8/10 Excellent! (331 reviews) "Solo woman traveler here. Felt very safe. Loved the convenience and options of breakfast every morning. The garden is lovely and wished I had spent more time there. The room was nothing fancy, but my time there was great. Thankfully nobody was staying next door to my room because the last night I ..." Reviewed on Sep 26, 2025 [](https://expedia.ca/Hotel-Search?startDate=02%2F11%2F2025&endDate=03%2F11%2F2025&selected=17907720&PinnedHotelID=17907720&HadPinnedHotel=true®ionId=553248633938935375) ![Hotel Firenze 2000](https://images.trvl-media.com/lodging/19000000/18670000/18665200/18665170/99e71450_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Firenze 2000 Viale Raffaello Sanzio, 16, Florence, FI Fully refundableReserve now, pay when you stay CA $122 CA $149 total Nov 13 - Nov 14 includes taxes & fees Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Popular attractions Ponte Vecchio and Uffizi Gallery are located ... 7.2/10 Good! (183 reviews) "The staff was wonderful and very helpful; 24 hr service ! The room was very clean and breakfast was plentiful. Great location if you don’t mind a short walk to the historic town center ; would definitely recommend." Reviewed on Oct 4, 2025 [](https://expedia.ca/Hotel-Search?startDate=13%2F11%2F2025&endDate=14%2F11%2F2025&selected=18665170&PinnedHotelID=18665170&HadPinnedHotel=true®ionId=553248633938935375) [See all 474 properties in Santo Spirito](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=14%2F10%2F2025&endDate=15%2F10%2F2025®ionId=553248633938935375) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santo Spirito hotel availability [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-13&endDate=2025-10-14) [Tonight](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-13&endDate=2025-10-14) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-13&endDate=2025-10-14) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-13&endDate=2025-10-14)[Oct 13 - Oct 14](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-13&endDate=2025-10-14) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-14&endDate=2025-10-15) [Tomorrow night](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-14&endDate=2025-10-15) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-14&endDate=2025-10-15) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-14&endDate=2025-10-15)[Oct 14 - Oct 15](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=2025-10-14&endDate=2025-10-15) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [This weekend](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025)[Oct 17 - Oct 19](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=17%2F10%2F2025&endDate=19%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [Next weekend](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) [](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025)[Oct 24 - Oct 26](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248633938935375&startDate=24%2F10%2F2025&endDate=26%2F10%2F2025) * * * ### Other neighbourhoods around Santo Spirito ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/409000/409788-Brancacci-Chapel.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Frediano San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica. [](https://expedia.ca/San-Frediano.dx6141947) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408952-Italy.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Oltrarno 4.5/5(77 area reviews) South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo. [](https://expedia.ca/Florence-Oltrarno.dx6084345) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410264-Santa-Maria-Novella.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Santa Maria Novella 4.5/5(225 area reviews) Enjoy the popular shops in Santa Maria Novella. The New Florence Opera House is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato. [](https://expedia.ca/Florence-Santa-Maria-Novella.dx6084343) ![Uffizi Gallery featuring street scenes as well as a large group of people](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/31000/31661-Uffizi-Gallery-Galleria-Degli-Uffizi.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### San Giovanni If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing. [](https://expedia.ca/Florence-San-Giovanni.dx553248635976383065) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/410000/410270-Duomo-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Duomo 5/5(339 area reviews) Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops. [](https://expedia.ca/Florence-Duomo.dx6084346) ![Default Image](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/408000/408985-Florence.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Historic Centre of Florence Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city. [](https://expedia.ca/Florence-Historic-Centre-Of-Florence.dx6141938) * * * * * * - [Stays](?pwaLob=wizard-hotel-pwa-v2) - [Packages](?pwaLob=wizard-package-pwa) - [Flights](?pwaLob=wizard-flight-pwa) - [Things to do](?pwaLob=wizard-lx-pwa) - [Cruises](?pwaLob=wizard-cruise-pwa) - [Cars](?pwaLob=wizard-car-pwa) # Santo Spirito ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - [4 Star Hotels in Florence](https://www.expedia.ca/4Star-Florence-Hotels.s40-0-d1222.Travel-Guide-Filter-Hotels) - [Hotels near Boboli Gardens](https://www.expedia.ca/Boboli-Gardens-Hotels.0-l507684-0.Travel-Guide-Filter-Hotels) - [Winery Hotels in Province of Florence](https://www.expedia.ca/Destinations-In-Province-Of-Florence-Winery-Hotel.0-0-d179893-tWineryHotel.Hotel-Filter-Destinations) - [Province of Florence Hotels](https://www.expedia.ca/Destinations-In-Province-Of-Florence.d179893.Hotel-Destinations) - [All Inclusive Resorts and in Tuscany](https://www.expedia.ca/Destinations-In-Tuscany-All-Inclusive-Hotel.0-0-d601686-tAllInclusiveHotel.Hotel-Filter-Destinations) - 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