When is the best time to go to Enterprise?

The best times to visit Enterprise are during the late spring (May to early June) and early autumn (September to October). During these periods, the weather is pleasantly mild, making it ideal for exploring the outdoor attractions. You'll find comfortable temperatures for walking around the town centre, visiting the local parks, or enjoying a leisurely afternoon at the Enterprise Farmers Market. These months also avoid the peak summer crowds and the colder winter conditions, offering a more relaxed experience. For those interested in outdoor activities like hiking or cycling, late spring brings blossoming flowers and lush greenery, while early autumn offers beautiful foliage colours.

Can I cancel my hotel reservation on Expedia?

Many Expedia hotel reservations are refundable, provided that you cancel before the hotel’s cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Enterprise hotel for you.

How much is the nightly rate at a Enterprise hotel?

Hotel prices in Enterprise often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

10 Best Hotels in Enterprise, Des Moines for 2026

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Our top choices for Enterprise hotels

A La Quinta hotel with a modern design, featuring a prominent sign, a covered entrance, and a brick facade.

1. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

4.6 km from Enterprise

Gregory J

CA $127 total

includes taxes & fees

Oct 28 - Oct 29

An outdoor patio area with wooden beams and string lights, furnished with chairs and tables, and a stone wall backdrop.

2. Best Western Premier Des Moines-Ankeny Hotel

4.6 km from Enterprise

Delta

CA $126 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a desk with a computer, a TV, and artwork on the wall.

3. Sleep Inn & Suites Ankeny - Des Moines

4.7 km from Enterprise

Brian

CA $147 total

includes taxes & fees

Nov 22 - Nov 23

A swimming pool with four lounge chairs and a view of trees through large windows.

4. Holiday Inn Express Des Moines Ankeny by IHG

5.6 km from Enterprise

gary

CA $149 total

includes taxes & fees

Nov 7 - Nov 8

A hotel exterior with a stone fire feature, outdoor seating, and a curved building facade.

5. Courtyard Marriott Ankeny

4.4 km from Enterprise

michael

CA $153 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio with a round table and chairs, a view of a lake, and a grassy area with trees.

6. Country Inn & Suites by Radisson, Ankeny - Des Moines

4.7 km from Enterprise

Gayle

CA $137 total

includes taxes & fees

Nov 15 - Nov 16

An indoor swimming pool with wooden ceiling beams, tiled walls, and a clear view of the outside through large windows.

7. AmericInn by Wyndham Ankeny/Des Moines

4.6 km from Enterprise

Leslie

CA $131 total

includes taxes & fees

Nov 12 - Nov 13

A hotel lobby with a reception desk, seating area with a sofa and chairs, a coffee station, and a dining area.

8. Comfort Inn & Suites Ankeny - Des Moines

4.2 km from Enterprise

Christopher

CA $124 total

includes taxes & fees

Nov 23 - Nov 24

An outdoor patio area with wicker furniture, a fire pit, and a view of the building's exterior.

9. Staybridge Suites Des Moines North Ankeny by IHG

5.7 km from Enterprise

Carl

CA $185 total

includes taxes & fees

Oct 29 - Oct 30

A modern lounge area with a central table, seating arrangements, and a decorative ceiling piece.

10. Hampton Inn & Suites Ankeny

5.3 km from Enterprise

Cara

CA $172 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor patio area with a grill, seating, and string lights.

11. Homewood Suites By Hilton Ankeny

4.5 km from Enterprise

Judy

CA $185 total

includes taxes & fees

Nov 1 - Nov 2

12. My Place Hotel - Ankeny/ Des Moines, IA

4.6 km from Enterprise

Christina

CA $133 total

includes taxes & fees

Oct 27 - Oct 28

An indoor swimming pool with clear water, tiled walls, and a no diving sign.

13. La Quinta by Wyndham Altoona Des Moines

8.7 km from Enterprise

Michael

CA $127 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a bedside table with a lamp, a framed artwork on the wall, and a door with a sign.

14. Econo Lodge Ankeny - Des Moines

4.7 km from Enterprise

Teri

CA $109 total

includes taxes & fees

Nov 23 - Nov 24

A hotel room with two beds, a nightstand with a phone, and a view of autumn foliage through large windows.

15. Quality Inn & Suites Ankeny - Des Moines

4.2 km from Enterprise

Edward

CA $101 total

includes taxes & fees

Nov 1 - Nov 2

A Holiday Inn Express & Suites hotel with a covered entrance and a brick facade.

16. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

9.2 km from Enterprise

rick

CA $155 total

includes taxes & fees

Nov 23 - Nov 24

A hotel with a reflection in a calm body of water, surrounded by open fields.

17. Fairfield Inn & Suites Des Moines Altoona

8.9 km from Enterprise

Jeffrey

CA $179 total

includes taxes & fees

Nov 15 - Nov 16

18. Home2 Suites By Hilton Altoona Des Moines

9.3 km from Enterprise

todd m

CA $154 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a bar area, wooden cabinets, and a large window.

19. Tru By Hilton Ankeny

7.4 km from Enterprise

MELINDA

CA $159 total

includes taxes & fees

Nov 1 - Nov 2

A modern bar area with a long counter, multiple bar stools, and hanging pendant lights.

20. Hampton Inn & Suites Altoona-Des Moines

9.1 km from Enterprise

Christy

CA $174 total

includes taxes & fees

Nov 8 - Nov 9

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Compare popular hotels in Enterprise

Property	Star rating	Guest rating
Sleep Inn & Suites Ankeny - Des Moines	2.5 star property	9.2 Wonderful 996 reviews	View
La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA	3.0 star property	9.2 Wonderful 1,055 reviews	View
Holiday Inn Express Des Moines Ankeny by IHG	2.5 star property	9.4 Exceptional 373 reviews	View
Best Western Premier Des Moines-Ankeny Hotel	3.0 star property	9.0 Wonderful 960 reviews	View
Homewood Suites By Hilton Ankeny	3.0 star property	9.0 Wonderful 646 reviews	View

Where to stay in Enterprise

Find the best Enterprise areas and neighborhoods for the activities you enjoy most.

The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.

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Historic East Village

Directly east of Downtown Des Moines, this nationally recognized historic district boasts the Iowa State Capitol complex, State of Iowa Historical Museum, and Des Moines Botanical Gardens. Explore eateries, boutique shops, and loft-style housing in its charming structures.

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A city skyline at night with illuminated buildings and a prominent tower.

Court District

Court District is known for its ample dining options, and you can make a stop by Science Center of Iowa and Principal Park while in the area.

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The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.

Drake

If you're spending some time in Drake, Knapp Center and Des Moines Community Playhouse are top sights worth seeing.

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A city skyline at dusk with illuminated buildings, a bridge, and a river.

Beaverdale

If you're looking for some top things to see and do in Beaverdale and surrounding area, you can visit Merle Hay Mall and Knapp Center.

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Top Enterprise Hotel Reviews

Wildwood Lodge

10/10 Excellent

"Clean, quiet, friendly"

Des Moines Marriott Downtown

10/10 Excellent

"I. loved the very clean room, excellent pillows, amazing bathroom lighting, and the fact that even with a full hotel, elevators were coming quickly. The food at our luncheon and banquet was meh, but that was ok. Bathrooms at our convention got dirty and should have been serviced between our breaks, but otherwise everything was very good. One problem however, we reserved a room with two queens and they gave us a king, so we cancelled our reservation and came back by Expedia. A bit more pricey, but still fine."

Stoney Creek Hotel Des Moines - Johnston

10/10 Excellent

"Room was spacious and clean. Front desk helped explain anything and everything to us about any questions we had. Breakfast was a pretty standard continental breakfast, but I did enjoy a few items that I do not normally see at hotels. This was our first stay at this location, but I will definitely book this hotel again in the near future!"

Hotels in Enterprise, Des Moines

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Star rating

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Our top choices for Enterprise hotels

1. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

2. Best Western Premier Des Moines-Ankeny Hotel

3. Sleep Inn & Suites Ankeny - Des Moines

4. Holiday Inn Express Des Moines Ankeny by IHG

5. Courtyard Marriott Ankeny

6. Country Inn & Suites by Radisson, Ankeny - Des Moines

7. AmericInn by Wyndham Ankeny/Des Moines

8. Comfort Inn & Suites Ankeny - Des Moines

9. Staybridge Suites Des Moines North Ankeny by IHG

10. Hampton Inn & Suites Ankeny

11. Homewood Suites By Hilton Ankeny

12. My Place Hotel - Ankeny/ Des Moines, IA

13. La Quinta by Wyndham Altoona Des Moines

14. Econo Lodge Ankeny - Des Moines

15. Quality Inn & Suites Ankeny - Des Moines

16. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

17. Fairfield Inn & Suites Des Moines Altoona

18. Home2 Suites By Hilton Altoona Des Moines

19. Tru By Hilton Ankeny

20. Hampton Inn & Suites Altoona-Des Moines

Compare popular hotels in Enterprise

Where to stay in Enterprise

Downtown Des Moines

Historic East Village

Court District

Drake

Beaverdale

Top Enterprise Hotel Reviews

Wildwood Lodge

Frequently asked questions

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