Dupo Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $750 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Dupo Vacation

Book a Dupo vacation package and get set to experience the highlights of this city. Think about staying in the neighborhood of Soulard, which is great for distilleries and craft breweries, bars and pubs and markets. There's plenty to explore during your trip to Dupo, including Eckert’s Millstadt Farm and Triple Lakes Golf Course. Whoever you're taking time off with and whatever you plan to spend, your ultimate Dupo vacation is just clicks away with Expedia.

Ready to book your vacation to Dupo?

 

Choose your dates

Dupo Hotel Deals

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $187 per night from May 8 to May 9
CA $187
CA $221 total
May 8 - May 9
includes taxes & fees
8.6/10 Excellent! (4,009 reviews)
Great location

Reviewed on Apr 20, 2026

Hyatt Regency St. Louis at The Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $136 per night from May 17 to May 18
CA $136
CA $159 total
May 17 - May 18
includes taxes & fees
9/10 Wonderful! (3,153 reviews)
Parking was secure and convenient. Breakfast was great!

Reviewed on Apr 22, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is CA $139 per night from May 3 to May 4
CA $139
CA $164 total
May 3 - May 4
includes taxes & fees
9.4/10 Exceptional! (2,944 reviews)
Upon arriving at the property, we were told we were at the wrong property. I didn't realize there were 2. Stephanie proceeded to switch the reservation so we wouldn't have to go across town after driving 8 hours already. I think she was sent from Heaven. We were pleasantly surprised to hear there ...

Reviewed on Apr 22, 2026

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.