A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for Defiance apartments

A hotel entrance with a stone facade, a covered walkway, and a red car parked outside.

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
7.0 out of 10, Good, (2 reviews)
"Property was dirty, kitchen hadn’t been cleaned. Microwave had food spilled all over inside. Place felt grimy."
United States
Jenny D.
The price is CA $231
CA $283 total
includes taxes & fees
Nov 12 - Nov 13
Great for Business Travelers! Pool + Gym
A front door with a sign for '2nd St Loft' and a 'Self Check In' option.

2. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (21 reviews)
"Everything was great room was very clean"
United States
Chance W.
The price is CA $131
CA $247 total
includes taxes & fees
Nov 15 - Nov 16
2nd Street Loft - Riverview
A wooden deck with a view of a parking area at dusk.

3. Enjoyable 2-bedroom apartment at St. Peters; Near STL

Enjoyable 2-bedroom apartment at St. Peters; Near STL
St. Peters
8.0 out of 10, Very good, (1 review)
"Very clean and comfortable. Pretty well-appointed. Could use an extra blanket or two. Overall good experience and would consider going again."
United States
Ronda S.
The price is CA $150
CA $379 total
includes taxes & fees
Nov 10 - Nov 11
Enjoyable 2-bedroom apartment at St. Peters; Near STL
A set of stone steps leading to a garage with a car parked inside.

4. Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
Ballwin
8.0 out of 10, Very good, (25 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is CA $95
CA $197 total
includes taxes & fees
Nov 15 - Nov 16
Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
A two-story building with a balcony, a staircase, and a gated entrance.

5. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (11 reviews)
"The property was clean and comfortable and everything you may need is there, walking distance was very close to everything in the area. Communication with the host was easy and quick responses, overall it was a great place to stay!"
United States
Melinda
The price is CA $137
CA $263 total
includes taxes & fees
Nov 15 - Nov 16
2nd Street -Deck Suite (back entrance)
A modern kitchen with white cabinets, a black refrigerator, a stainless steel microwave, and a black oven. There are four blue bowls on a wooden table with a woven placemat.

6. Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi

Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
Moscow Mills
10.0 out of 10, Exceptional, (14 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is CA $162
CA $353 total
includes taxes & fees
Nov 10 - Nov 11
Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
A hotel room with a bed, a desk, a chair, a lamp, and a telephone.

7. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed

1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
Westport
9.4 out of 10, Exceptional, (43 reviews)
"Great spot!"
United States
Anonymous traveller
The price is CA $78
CA $90 total
includes taxes & fees
Nov 11 - Nov 12
1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed
A spacious living room with hardwood floors, a white armchair, a sofa, and a TV on a stand.

8. The Cul-de-Sac Retreat

The Cul-de-Sac Retreat
Saint Charles
7.6 out of 10, Good, (10 reviews)
"Great house, great location - close to the St. Charles convention center"
United States
Joe H.
The Cul-de-Sac Retreat
A living room with a white sofa, two armchairs, a wooden coffee table, and a side table with a plant.

9. The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.8 out of 10, Excellent, (6 reviews)
"This was the perfect place for my friends and I to stay in Marthasville. Lots of space and amenities. We did not use the complimentary breakfast, but is a great addition. Would recommend to anyone staying in the area. "
United States
Adam K.
The price is CA $353
CA $656 total
includes taxes & fees
Nov 10 - Nov 11
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
A neatly made bed with a stack of folded towels, a bedside lamp, and a ceiling fan in a room with a large window and a wall-mounted artwork.

10. Home Near Main with Pet-Friendly Yard and Office

Home Near Main with Pet-Friendly Yard and Office
St. Charles Historic District
10.0 out of 10, Exceptional, (13 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is CA $162
CA $371 total
includes taxes & fees
Nov 12 - Nov 13
Home Near Main with Pet-Friendly Yard and Office
Free breakfast available on-site.

11. Studio | Lovely Suite Close to Edward Jones!

Studio | Lovely Suite Close to Edward Jones!
Westport
The price is CA $280
CA $340 total
includes taxes & fees
Nov 29 - Nov 30
Studio | Lovely Suite Close to Edward Jones!
A cozy living room with a brick wall, a white sofa with colorful cushions, a small black table, and a potted plant.

12. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (125 reviews)
"Great"
United States
Richard W.
The price is CA $137
CA $305 total
includes taxes & fees
Nov 11 - Nov 12
Prime Loft of Main Street
A living room with a black leather sofa, two grey armchairs, a wooden coffee table, and a wall clock.

13. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
9.0 out of 10, Wonderful, (4 reviews)
"Excellent"
United States
Scott N.
The price is CA $140
CA $389 total
includes taxes & fees
Nov 10 - Nov 11
6th street 101 - Walk to Main St
A modern living room with a leather sofa, a wooden coffee table, and a leather armchair. There is a painting on the wall and a lamp on a side table.

14. Foundry Flat on Main with Free Parking

Foundry Flat on Main with Free Parking
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
"Everything was exactly as described. St. Charles is an awesome place!"
United States
Michael
The price is CA $156
CA $424 total
includes taxes & fees
Nov 12 - Nov 13
Foundry Flat on Main with Free Parking
A modern kitchen with stainless steel appliances, white cabinetry, and a brick accent wall.

15. Historic Main St. Customs House Upstairs Apartment

Historic Main St. Customs House Upstairs Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Lovely place to stay!"
United States
Margaret A.
The price is CA $175
CA $486 total
includes taxes & fees
Nov 16 - Nov 17
Historic Main St. Customs House Upstairs Apartment
A modern kitchen with white cabinets, a built-in microwave, a stove, and a window providing natural light.

16. Pet-Friendly Duplex on Historic Main

Pet-Friendly Duplex on Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (26 reviews)
"Great location"
United States
todd p.
The price is CA $171
CA $383 total
includes taxes & fees
Nov 12 - Nov 13
Pet-Friendly Duplex on Historic Main
A staircase with white railings and a ceiling fan.

17. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (72 reviews)
"This was a prime spot for downtown activities! Near everything and not far from STL. Would absolutely stay here again!"
United States
Rebecca F.
The price is CA $157
CA $332 total
includes taxes & fees
Nov 10 - Nov 11
Amazing Renovated Historic Loft on Main Street
A spacious living area with a wooden floor, a dining table with chairs, a flat-screen TV mounted on the wall, and a kitchen area with modern appliances.

18. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (196 reviews)
"Very cute place, walking distance to everything."
United States
Liberty A.
The price is CA $157
CA $332 total
includes taxes & fees
Nov 10 - Nov 11
The Lofts of North Main Street
A row of multi-story buildings with commercial storefronts, including a cafe and a restaurant.

19. Dog-Friendly Studio on Historic Main Street

Dog-Friendly Studio on Historic Main Street
St. Charles Historic District
9.2 out of 10, Wonderful, (41 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is CA $130
CA $305 total
includes taxes & fees
Nov 15 - Nov 16
Dog-Friendly Studio on Historic Main Street
A hallway with a door, two potted plants, a doormat, and a view of a brick building through large windows.

20. Dog-Friendly 2BR Near Main Street

Dog-Friendly 2BR Near Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is CA $156
CA $415 total
includes taxes & fees
Nov 29 - Nov 30
Dog-Friendly 2BR Near Main Street
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

10/10 Excellent
"There was a large red wine stain next to the bed when we first walked in so I had to make sure with management that was not going to be charged on my end. Bathroom was very clean and the bed was comfy to sleep in. All workers were very nice. For the price, the hotel worked just fine for me. It was a place to sleep and get ready for the event we were attending."
Monica 2-night trip
Posted less than an hour ago
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Find out more about Defiance

Defiance Apartments information

Number of reviews
581
Accommodation
114 Apartments
Lowest Price
CA $90
Highest Price
CA $656

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights, 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and Smart TVs. 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights. Free WiFi and Smart TVs are included. The Lofts of North Main Street: Located in St. Charles, 19.2 mi/30.8 km away. Includes free WiFi, sofa beds, and Smart TVs. Access to onsite laundry facilities is available on site. Driftwood Den | Boho 2BR | Dog-Friendly: It's located in St. Charles, 19 mi/30.6 km from Defiance. Includes free WiFi.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

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