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Check prices for these dates

In two weeks
Feb 20 - Feb 22
In two months
Apr 3 - Apr 5
In three months
May 1 - May 3
In four months
May 29 - May 31

Our top choices for Defiance apartments

TV, fireplace

2-bedroom apartment in awesome West County with AC, Fitness Room and Laundry

2-bedroom apartment in awesome West County with AC, Fitness Room and Laundry
St. Louis
10.0 out of 10, Exceptional, (1 review)
2-bedroom apartment in awesome West County with AC, Fitness Room and Laundry
TV

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
The price is CA $122
CA $375 total
includes taxes & fees
Feb 9 - Feb 10
6th street 101 - Walk to Main St
Exterior

2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (2 reviews)
"Easy check in/check out, super nice host! Very clean space. "
United States
Emily L.
The price is CA $131
CA $227 total
includes taxes & fees
Feb 9 - Feb 10
2nd Street -Deck Suite (back entrance)
Dining

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
Maryland Heights
9.6 out of 10, Exceptional, (4 reviews)
"It was an easy experience renting this place"
United States
Dominic M.
The price is CA $195
CA $253 total
includes taxes & fees
Feb 16 - Feb 17
Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
Living area

The Cul-de-Sac Retreat

The Cul-de-Sac Retreat
Saint Charles
8.4 out of 10, Very good, (9 reviews)
"Great house, great location - close to the St. Charles convention center"
United States
Joe H.
The price is CA $153
CA $346 total
includes taxes & fees
Feb 9 - Feb 10
The Cul-de-Sac Retreat
Interior

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (58 reviews)
"Great place and location. Owners were easy to work with."
United States
Cory M.
The price is CA $163
CA $348 total
includes taxes & fees
Feb 9 - Feb 10
Amazing Renovated Historic Loft on Main Street
Interior

Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street

Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street
Saint Charles
9.0 out of 10, Wonderful, (2 reviews)
"The overall vibe struck me as a college town apartment: the building was fine, but finishes were underwhelming. The unit itself was a little small, but workable. We had a scenario where the heater seemed to be acting up; the room actually got warmer after we shut the heat off. It was a pleasant enough stay, and served the purpose we had come for: visiting our adult children. It was a bit of a walk to get to the historic district."
United States
Greg L.
The price is CA $139
CA $386 total
includes taxes & fees
Feb 9 - Feb 10
Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street
Exterior

Sunny SparkingClean King bed Apt- CreveCoeurPark

Sunny SparkingClean King bed Apt- CreveCoeurPark
Maryland Heights
9.8 out of 10, Exceptional, (12 reviews)
"Good Stay"
United States
Lanai
The price is CA $204
CA $386 total
includes taxes & fees
Mar 4 - Mar 5
Sunny SparkingClean King bed Apt- CreveCoeurPark
Fridge, microwave, oven, stovetop

Main Street Living! 2 Bedroom Unit right On Main!

Main Street Living! 2 Bedroom Unit right On Main!
St. Charles Historic District
9.6 out of 10, Exceptional, (35 reviews)
"Great Stay and great location! "
United States
Angela
The price is CA $165
CA $472 total
includes taxes & fees
Feb 9 - Feb 10
Main Street Living! 2 Bedroom Unit right On Main!
Interior

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (159 reviews)
"Very nice place near all the action. "
United States
Weston G.
The price is CA $149
CA $328 total
includes taxes & fees
Feb 9 - Feb 10
The Lofts of North Main Street
A heated pool

Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
The price is CA $158
CA $214 total
includes taxes & fees
Feb 21 - Feb 22
Great for Business Travelers! Pool + Gym
Fridge, microwave, oven, stovetop

The Hidden Gem - 2BR Basement Apartment on 7 Acres

The Hidden Gem - 2BR Basement Apartment on 7 Acres
Moscow Mills
10.0 out of 10, Exceptional, (12 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is CA $188
CA $385 total
includes taxes & fees
Feb 10 - Feb 11
The Hidden Gem - 2BR Basement Apartment on 7 Acres
Interior

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
8.8 out of 10, Excellent, (15 reviews)
"Host was very welcoming and helpful when we have any questions no matter what time of day. The place was very quaint and comfy. We would highly recommend. "
United States
Chelsea L.
The price is CA $121
CA $284 total
includes taxes & fees
Feb 9 - Feb 10
The Historic Bricks on Main
Smart TV

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (104 reviews)
"The loft was very nice, very clean, well appointed, and in a perfect location. I highly recommend this property!"
United States
Mary ann S.
The price is CA $149
CA $328 total
includes taxes & fees
Feb 9 - Feb 10
Prime Loft of Main Street
1 bedroom, WiFi, bed sheets

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is CA $121
CA $310 total
includes taxes & fees
Feb 9 - Feb 10
Duplex Hideaway in St. Charles, MO
TV

Back Door Guest Suite, Zia My Retreat

Back Door Guest Suite, Zia My Retreat
New Haven
10.0 out of 10, Exceptional, (6 reviews)
"Very comfortable, spacious, great location for canoe trip. "
United States
Carolyn B.
The price is CA $185
CA $313 total
includes taxes & fees
Feb 9 - Feb 10
Back Door Guest Suite, Zia My Retreat
Fridge, microwave, stovetop, toaster

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
10.0 out of 10, Exceptional, (16 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
The price is CA $133
CA $325 total
includes taxes & fees
Feb 9 - Feb 10
Charming Duplex on Main
TV

Main Street Balcony Apartment by StayLage!

Main Street Balcony Apartment by StayLage!
St. Charles Historic District
9.6 out of 10, Exceptional, (36 reviews)
"The unit was so nice and clean. We enjoyed being right on Main St, close to shops and dining. "
United States
Laura L.
The price is CA $258
CA $661 total
includes taxes & fees
Feb 14 - Feb 15
Main Street Balcony Apartment by StayLage!
Exterior

Studio on Historic Main by StayLage

Studio on Historic Main by StayLage
St. Charles Historic District
9.0 out of 10, Wonderful, (33 reviews)
"Nice property.. Clean. "
United States
Belinda J.
The price is CA $103
CA $261 total
includes taxes & fees
Feb 16 - Feb 17
Studio on Historic Main by StayLage
Interior

AK`s STL Pearl Grey House - Game Room

AK`s STL Pearl Grey House - Game Room
Maryland Heights
9.0 out of 10, Wonderful, (8 reviews)
"My kids loved this house! It was very comfortable for my family of 7. We were able to cook dinner, play games, watch TV, and were within close proximity to all things St. Louis. We would definitely stay here again. "
United States
Tiffanny B.
The price is CA $292
CA $644 total
includes taxes & fees
Feb 9 - Feb 10
AK`s STL Pearl Grey House - Game Room
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

10/10 Excellent
"Everything was very, very nice. The casino smoke was unfortunate, but was not noticable in the room, of course."
shawn 1-night trip
Posted 17 hours ago
Hollywood Casino & Hotel St. Louis

Find out more about Defiance

Defiance Apartments information

Number of reviews
491
Accommodation
103 Apartments
Lowest Price
CA $214
Highest Price
CA $661

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here's a top apartment in the area: 'the Ruebling House': Bright, Modern, & Renovated!: Situated in Defiance, 0.1 mi/0.2 km from the heart of Defiance.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you're planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, you may want a rental car for your journey.

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