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De Soto Vacation Rentals

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Our top choices for De Soto vacation rentals

1. The Cozy Corner

The Cozy Corner
De Soto
10.0 out of 10, Exceptional, (3 reviews)
"Extremely clean, beautifully decorated and every amenity a person could possibly need. Great response time."
United States
yvonne o.
The price is CA $162
CA $199 total
includes taxes & fees
Nov 15 - Nov 16
The Cozy Corner

2. The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.
Murphysboro
9.6 out of 10, Exceptional, (35 reviews)
"We enjoyed our visit"
United States
Tim P.
The price is CA $172
CA $267 total
includes taxes & fees
Nov 16 - Nov 17
The Lab! Come stay in our brand new space.

3. Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
3.0 star property
Murphysboro
The price is CA $169
CA $332 total
includes taxes & fees
Nov 23 - Nov 24
Pet Friendly! Couples Retreat in Southern Illinois

4. Step In To the Mediterranean

Step In To the Mediterranean
Carbondale
9.8 out of 10, Exceptional, (8 reviews)
"Such a comfortable place to stay and great communication."
United States
Marina C.
The price is CA $529
CA $1,288 total
includes taxes & fees
Nov 11 - Nov 12
Step In To the Mediterranean

5. Minutes from Lake |Fire Pit | Like-New 3BR Retreat

Minutes from Lake |Fire Pit | Like-New 3BR Retreat
Murphysboro
9.8 out of 10, Exceptional, (7 reviews)
"Everything with the house was great. Even the minor issues with the internet and washer going down were handled quick. Beautiful property and very communicative"
United States
Scott M.
The price is CA $247
CA $620 total
includes taxes & fees
Nov 16 - Nov 17
Minutes from Lake |Fire Pit | Like-New 3BR Retreat

6. Fishing Cabin next to Kinkaid Lake

Fishing Cabin next to Kinkaid Lake
Murphysboro
10.0 out of 10, Exceptional, (4 reviews)
"Everything was very clean, parking was easy and plenty of room for the truck and boat. Check in was very easy and great contact with very quick responses. Definitely recommend to stay here."
United States
Dustin M.
The price is CA $240
CA $341 total
includes taxes & fees
Nov 23 - Nov 24
Fishing Cabin next to Kinkaid Lake

7. Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.
Oraville
9.4 out of 10, Exceptional, (3 reviews)
"Great place great communication"
United States
Kevin E.
The price is CA $155
CA $183 total
includes taxes & fees
Nov 11 - Nov 12
Lois' Hideout Comfy 1 bedroom camper within 7 minutes of Kinkaid Lake.

8. Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress
Oraville
9.4 out of 10, Exceptional, (3 reviews)
"Had a nice time. Loved staying in the camper. The host was very prompt when communicating. Would definitely stay again."
United States
Joseph S.
The price is CA $176
CA $206 total
includes taxes & fees
Nov 11 - Nov 12
Kinkaid Kamper with AC in Oraville - 2 bedrooms for a cozy stay. house mattress

9. Screened Hot Tub & Peacocks Nearby

Screened Hot Tub & Peacocks Nearby
Carbondale
10.0 out of 10, Exceptional, (118 reviews)
"Thank you for the lovely stay!"
United States
Stacey K.
The price is CA $375
CA $438 total
includes taxes & fees
Nov 29 - Nov 30
Screened Hot Tub & Peacocks Nearby

10. Located in the Luxurious Pine Manor Estates!

Located in the Luxurious Pine Manor Estates!
Carbondale
10.0 out of 10, Exceptional, (3 reviews)
"This is our second stay at Pine Manor, once in one of the larger homes with our extended family and this time in the carriage house. Both stays were perfect. The accommodations are exception quality and the location idea for our days at Southern Illinois University and the area."
United States
adaire p.
The price is CA $210
CA $549 total
includes taxes & fees
Dec 3 - Dec 4
Located in the Luxurious Pine Manor Estates!

11. The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit

The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit
Murphysboro
8.0 out of 10, Very good, (1 review)
"Place overall was decent, it was clean enough. The hot tub and fire pit were a nice touch. The house is very close to the road and there is constant traffic noise even late at night. It is also advertised as more upscale than it was. We noticed several areas of the house that looked like the landlord special took place in getting it ready. Some of the doors didn’t close properly or were only on a single set of hinges instead of multiple. The dining chairs too were not in great shape, they had...
United States
Calista
The price is CA $138
CA $320 total
includes taxes & fees
Dec 1 - Dec 2
The Lux Collective- Private Hot Tub, Dry Bar, 1-Acre Yard & Fire Pit

12. Third-Floor Suite, SIU Across Street

Third-Floor Suite, SIU Across Street
Carbondale
10.0 out of 10, Exceptional, (36 reviews)
"Everything has good. Would stay here again."
United States
Kathy A.
The price is CA $279
CA $344 total
includes taxes & fees
Nov 16 - Nov 17
Third-Floor Suite, SIU Across Street

13. Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.
Oraville
10.0 out of 10, Exceptional, (6 reviews)
"Very nice place, will definitely be back."
United States
Greg W.
The price is CA $212
CA $244 total
includes taxes & fees
Nov 15 - Nov 16
Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

14. Lakeside 1-bedroom located at Crab Orchard Lake near SIU. Cabin #16

Lakeside 1-bedroom located at Crab Orchard Lake near SIU. Cabin #16
Carbondale
The price is CA $239
CA $323 total
includes taxes & fees
Nov 19 - Nov 20
Lakeside 1-bedroom located at Crab Orchard Lake near SIU. Cabin #16

15. 3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (80 reviews)
"Very clean and comfortable stay"
United States
Alison K.
The price is CA $145
CA $249 total
includes taxes & fees
Nov 11 - Nov 12
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

16. Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!
Makanda
9.8 out of 10, Exceptional, (34 reviews)
"Great host, amenities, and location!"
United States
Kevin W.
The price is CA $165
CA $193 total
includes taxes & fees
Nov 19 - Nov 20
Fantastic 1-bedroom Cabin in peaceful Makanda, Pet-Friendly!

17. Hot Tub Cabin- In the Heart of Shawnee Wine Trail

Hot Tub Cabin- In the Heart of Shawnee Wine Trail
Carbondale
10.0 out of 10, Exceptional, (5 reviews)
"Loved the cabin and the hot tub. Very relaxing, we will definitely be back."
United States
Jonathan G.
The price is CA $299
CA $411 total
includes taxes & fees
Nov 22 - Nov 23
Hot Tub Cabin- In the Heart of Shawnee Wine Trail

18. Charming 3 bedroom retreat

Charming 3 bedroom retreat
Herrin
10.0 out of 10, Exceptional, (4 reviews)
"Great property, very clean and had everything you could possibly need. We were in town for a wedding and this worked perfect for my group!!! Would definitely recommend!"
United States
Christina H.
The price is CA $176
CA $384 total
includes taxes & fees
Nov 16 - Nov 17
Charming 3 bedroom retreat

19. 30-Acre Woods, Trail & Salt Hot Tub

30-Acre Woods, Trail & Salt Hot Tub
Carbondale
10.0 out of 10, Exceptional, (38 reviews)
"We were very happy with our stay!"
United States
Jody O.
The price is CA $394
CA $472 total
includes taxes & fees
Nov 30 - Dec 1
30-Acre Woods, Trail & Salt Hot Tub

20. Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.8 out of 10, Exceptional, (58 reviews)
"We enjoyed our stay at the well outfitted cabin near the Shawnee Wine Trail. Cabin is conveniently located near Giant City State Park and the lodge restaurant. "
United States
Janine B.
The price is CA $169
CA $314 total
includes taxes & fees
Nov 23 - Nov 24
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top De Soto Hotel Reviews

Find out more about De Soto

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with De Soto. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in De Soto?

Yes, you can find vacation rentals near well known local attractions in De Soto, or you can choose a secluded option if you're looking for a relaxing stay.

What are some of the best vacation home rentals in De Soto?

* On the Wine Trail * Hot Tub * Wi-Fi *: This vacation home rental outside of De Soto is located on a lake and has a patio, a hot tub, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What can I see and do in De Soto?

While you're exploring the area, De Soto City Park and Little Grand Canyon Trail Trailhead are a couple of picturesque spots to get outside and enjoy nature. Southern Illinois University and Crab Orchard Golf Club are a couple of places you'll find in the larger area.

What are vacation rentals like in De Soto?

Vacation rentals are private accommodations you can stay in for several days or longer in De Soto. Vacation rentals feature amenities such as kitchens and laundry facilities so you'll have everything you need. If you're concerned about cleanliness, vacation rentals can offer a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for a family trip.