Book The Best Hotels in De Soto, IL for 2026 from CA $96 - Fully Refundable Options

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Our top choices for De Soto hotels

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

A conference room with tables, chairs, a flat-screen TV, and a sign indicating amenities.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

A buffet with various food items, including omelets and other dishes, with clear signage indicating the type of food.

1. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

Lauren

CA $148

CA $165 total

includes taxes & fees

Oct 26 - Oct 27

A hotel entrance with a 'Welcome' sign and a 'Hampton Inn' sign.

A lobby with a patterned carpet, a yellow armchair, a glass door entrance, and shelves stocked with snacks and beverages.

An indoor swimming pool with a lifeguard chair, poolside seating, and a clear view of the outdoors.

A reception area with a reception desk, a waiting area with a patterned armchair, and a reception counter with a computer and framed pictures.

2. Hampton Inn Carbondale

Carbondale

Michelle

CA $144

CA $165 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with two beds, a desk, a chair, a TV, a lamp, and a painting on the wall.

A bar area with multiple stools, a bar counter, shelves of liquor bottles, and hanging pendant lights.

A modern restaurant with a bar area, multiple tables and chairs, and a kitchen in the background.

An indoor swimming pool with clear blue water, a sunshade, and a seating area with chairs and a table.

3. Best Western Saluki Inn

Carbondale

Bryan

CA $128

CA $150 total

includes taxes & fees

Oct 11 - Oct 12

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.

A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.

A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.

A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

4. Walker's Bluff Casino Resort

Carterville

Kyle

CA $201

CA $223 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a wooden headboard, two bedside lamps, a nightstand, and a separate bathroom with a bathtub.

A Comfort Inn with a two-story building, a covered entrance, and a parking lot.

A modern coffee shop with wooden cabinets, a coffee machine, and a seating area with red chairs.

A modern living room with a stone fireplace, blue sofas, a flat-screen TV, and a patterned carpet.

5. Comfort Inn & Suites Carbondale University Area

Carbondale

Bill

CA $119

CA $137 total

includes taxes & fees

Oct 1 - Oct 2

An outdoor patio with stone fire pit, colorful striped sofas, and blue chairs.

A spacious lobby with a central seating area, a large window, and a reception desk.

A modern kitchen with a stainless steel refrigerator, microwave, and dishwasher. There is a window providing natural light and a view of the outdoors.

A hotel with a covered entrance, outdoor seating, and a flag.

6. Home2 Suites by Hilton Carbondale

Carbondale

Alyssa

CA $170

CA $196 total

includes taxes & fees

Oct 26 - Oct 27

A room with a brown sofa, a brown armchair, a patterned carpet, a lamp, and a window with curtains.

A hotel lobby with a reception desk, several tables and chairs, framed pictures on the walls, and a clock.

A hotel room with a large bed, a desk, a chair, a window with curtains, a wall-mounted TV, and a large painting.

A hotel with a Super 8 sign, multiple parking spaces, and a brick facade.

7. Super 8 by Wyndham Carbondale

Carbondale

Erin

CA $92

CA $105 total

includes taxes & fees

Sep 29 - Sep 30

A modern interior with a staircase, a checkered floor, and a view through large windows.

An empty parking lot with trees and a grassy field in the background.

A hotel room with a bed, two red chairs, a table, a TV, and a window with curtains.

A dining area with a round table and four chairs, a television mounted on the wall, and a framed picture above the table.

8. University Inn of Carbondale

Carbondale

Amitabh

CA $94

CA $108 total

includes taxes & fees

Sep 27 - Sep 28

A building with a covered entrance, a parking lot, and a tree.

A hotel dining area with tables and chairs, a buffet counter, and a television mounted on the wall.

A hotel lobby with leather sofas, a reception desk, an exit sign, and a view of the outdoors.

A hotel reception area with a reception desk, a TV, and a seating area with a sofa and table.

9. Quality Inn Carbondale University area

Carbondale

Montreal

CA $87

CA $100 total

includes taxes & fees

Sep 29 - Sep 30

A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.

A spacious lobby with a high ceiling, a central seating area with multiple chairs, a reception desk, and a kitchen area in the background.

An outdoor patio area with a table and chairs, a red umbrella, and a brick building facade.

10. Drury Inn & Suites Marion

Marion

kevin

CA $135

CA $162 total

includes taxes & fees

Oct 18 - Oct 19

A modern dining area with round tables and chairs, large windows, and a chandelier.

A swimming pool with water slides, sun umbrellas, and lounge chairs.

A spacious indoor area with large windows, multiple seating arrangements including tables and chairs, and a patterned sofa.

A modern hotel room with a large bed, a bedside table with a phone, a small shelf, and a wall-mounted artwork.

11. Holiday Inn Express & Suites Carbondale - University Area by IHG

Carbondale

Monica

CA $163

CA $187 total

includes taxes & fees

Oct 26 - Oct 27

A lobby with a sofa, chairs, a fireplace, a clock, and framed pictures on the wall.

A Fairgrounds Inn building with a beige facade, multiple windows, and a snow-covered roof.

A dining area with wooden tables and chairs, a kitchen area, and a framed picture on the wall.

An indoor swimming pool with clear water, a metal ladder, and lounge chairs in the background.

12. Fairgrounds Inn

Du Quoin

Kasey

CA $117

CA $130 total

includes taxes & fees

Oct 5 - Oct 6

A Comfort Inn & Suites hotel with a modern design, featuring a covered entrance and landscaped gardens.

A modern kitchen with a central island, bar stools, and various appliances.

A golf course with a flagstick, trees, and a water hazard.

A spacious lobby with a reception desk, seating area, and a kitchen in the background.

13. Comfort Inn & Suites Marion I-57

Marion

Daniel

CA $153

CA $183 total

includes taxes & fees

Oct 25 - Oct 26

A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

A modern living room with a sofa, coffee table, and a dining area with chairs.

A reception area with a wooden counter, a welcome mat, and framed artwork on the wall.

A Country Inn & Suites building with a covered entrance and a parking lot.

14. Country Inn & Suites by Radisson, Marion, IL

Marion

Brianna

CA $126

CA $151 total

includes taxes & fees

Oct 18 - Oct 19

A bathroom with a bathtub, a sink, and a mirror.

A two-story motel with a covered entrance and a parking lot.

A room with a bed, a bench, a sink, a door, and a bathtub.

A living room with a sofa, a wooden table, a television, a microwave, and a window with curtains.

15. Americas Best Value Inn West Frankfort

West Frankfort

Christopher

CA $96

CA $106 total

includes taxes & fees

Sep 27 - Sep 28

A spacious lobby with a patterned carpet, a fireplace, seating area, and a staircase.

A spacious lobby with a patterned carpet, a staircase, a fireplace, and seating areas.

An indoor swimming pool with clear blue water, surrounded by beige and red tiled flooring, and equipped with multiple ladders and chairs.

A breakfast area with wooden cabinets, a coffee machine, a toaster, and a sign reading "Breakfast Corner".

16. Baymont by Wyndham Marion

Marion

Toni

CA $136

CA $163 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a large bed, a desk with a chair, a television, and a window with curtains.

A Super 8 hotel with a brick facade, multiple windows, and a parking lot.

A reception area with a stone counter, a clock, and a reception desk.

A dining area with wooden tables and chairs, framed artwork on the walls, and a window view.

17. Super 8 by Wyndham Marion

Marion

misty

CA $100

CA $120 total

includes taxes & fees

Sep 26 - Sep 27

A self-service breakfast area with a coffee machine, refrigerated display case, and various food items.

A hotel room with a bed, a television, a desk, a coffee machine, and a bathroom visible through an open door.

A Best Western hotel with a parking lot and a covered entrance.

A gym with treadmills, ellipticals, and weight machines.

18. Best Western Marion Hotel

Marion

Cornell

CA $108

CA $130 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a desk, a dresser, a mirror, and a nightstand with a lamp.

A lobby with a reception desk, seating area, and a fireplace.

A reception area with a wooden counter, a clock, and a door leading outside.

A compact hotel room with a kitchenette, a single bed, a desk with a chair, a TV, and a window with curtains.

19. Motel 6 Marion, IL

Marion

Jessie

CA $92

CA $102 total

includes taxes & fees

Sep 27 - Sep 28

A hotel lobby with wooden beams, a reception desk, a coffee machine, and a display of food items.

A kitchen with wooden cabinets, a microwave, a coffee machine, and various appliances.

A dining area with wooden tables and chairs, a TV mounted on the wall, and a kitchen area with wooden cabinets and a countertop.

A hotel room with a large bed, a desk with a lamp, a chair, an air conditioning unit, and a television.

20. Quality Inn & Suites Marion

Marion

Thomas

CA $100

CA $120 total

includes taxes & fees

Oct 4 - Oct 5

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De Soto City Park

Explore the great outdoors at De Soto City Park, a lovely green space in De Soto.

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Top De Soto Hotel Reviews

Super 8 by Wyndham Marion

8/10 Good

"Staff was helpful Breakfast they had biscuits and gravy waffles and etc pretty good I always enjoy the breakfast !"

Motel 6 Marion, IL

8/10 Good

"The desk agent was sensitive to and responsive to special access needs. We were very thankful."

Super 8 by Wyndham Carbondale

10/10 Excellent

"Rooms were clean, AC was cold and the staff was friendly!"

Best Western Marion Hotel

10/10 Excellent

"Clean, friendly staff and nice breakfast. Would definitely stay again."

Walker's Bluff Casino Resort

8/10 Good

"Staff was very helpful checking me and my dog in. Was just passing by for the night was a good place to stop and recharge before continuing my journey. Would definitely visit again if life takes me in the area"

Baymont by Wyndham Marion

8/10 Good

"although not new the hotel was in good condition and the price was acceptable"

Quality Inn Carbondale University area

10/10 Excellent

"Easy to check in good staffs"

Quality Inn & Suites Marion

8/10 Good

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Cabin #1 w/ Private Beach 1 mi from Carbondale, IL and SIU

8/10 Good

"Host was nice....house and beach needed some tlc. House was for the most part clean. I would come back. Love how secluded and private the house was. Definitely a place for a group."

More cheap stays in De Soto