Title: Central San Diego Vacation Rentals from CA $138: Short-Term Rentals for 2025 | Expedia.ca [Central San Diego Travel Guide](https://expedia.ca/Central-San-Diego.dx6056570)[Hotels in Central San Diego](https://expedia.ca/Central-San-Diego-Hotels.d6056570.Travel-Guide-Hotels)[Flights to Central San Diego](https://expedia.ca/Cheap-Flights-To-Central-San-Diego.d6056570.Travel-Guide-Flights)[Things to do in Central San Diego](https://expedia.ca/Things-To-Do-In-Central-San-Diego.d6056570.Travel-Guide-Activities)[Central San Diego Car Rentals](https://expedia.ca/Car-Rentals-In-Central-San-Diego.d6056570.Car-Rental-Guide)[Central San Diego Vacation Packages](https://expedia.ca/Central-San-Diego.d6056570.Destination-Travel-Guides) ![Balboa Park featuring aircraft and interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/21000/21283-Balboa-Park.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Central San Diego Vacation Rentals ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Sep 22 - Sep 23](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-09-22&endDate=2025-09-23&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Sep 23 - Sep 24](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-09-23&endDate=2025-09-24&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Sep 26 - Sep 28](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-09-26&endDate=2025-09-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 3 - Oct 5](https://www.expedia.ca/Hotel-Search?regionId=6056570&startDate=2025-10-03&endDate=2025-10-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Vacation Rentals in Central San Diego ## Our top choices for Central San Diego vacation rentals ![Lobby sitting area](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/f051791c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/84cf0a12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/12939858.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, free WiFi, bed sheets](https://images.trvl-media.com/lodging/105000000/104290000/104283900/104283827/87b3eb35.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Uptown Inn by Vantaggio - Limited Service Apart-Hotel Hillcrest 8.2/10 Very good (226) "Honestly very clean rooms, the staff was wonderful and helpful " CA $122 CA $138 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/San-Diego-Hotels-Uptown-Inn.h104283827.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/79e8f033.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe 2 King Bedrooms, Multiple Beds, Sleeps 11ppl | Terrace/patio](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/6ef835b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bayview Condo - 2BR/3BA - Bunk Bed & Sofa Bed | Living area](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/48c0125d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/105000000/104150000/104140500/104140458/1b9a69bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### City24 Hotel Little Italy Mission Hills Middletown 9.6/10 Exceptional (89) "Great place to stay with my family of 9!!!" CA $175 CA $245 total includes taxes & fees Oct 6 - Oct 7 [](https://www.expedia.ca/San-Diego-Hotels-City24-Hotel-Little-Italy-Mission-Hill.h104140458.Hotel-Information) ![Coffee/tea maker](https://images.trvl-media.com/lodging/117000000/116670000/116665300/116665291/8036044d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/117000000/116670000/116665300/116665291/f206bdee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/117000000/116670000/116665300/116665291/ac86b231.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee/tea maker](https://images.trvl-media.com/lodging/117000000/116670000/116665300/116665291/91e0fcc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Inn at the Park by WorldMark Bankers Hill [](https://www.expedia.ca/San-Diego-Hotels-Inn-At-The-Park-By-WorldMark.h116665291.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/32000000/31850000/31846900/31846859/e03e81f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/32000000/31850000/31846900/31846859/651d51d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/32000000/31850000/31846900/31846859/65bad7fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/32000000/31850000/31846900/31846859/5bc75cfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Hideaway of Silver Terrace, located near Old Town, Sea World & Beaches. Linda Vista 9.4/10 Exceptional (50) "Great location and solid accommodations. Thank you Jimmy for a great stay!" [](https://www.expedia.ca/San-Diego-Hotels-Cozy-And-Affordable-1-Bedroom-Unit-Minutes-Away-From-Major-San-Diego-Attractions.h31846859.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/117000000/116220000/116218200/116218186/4647d9fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/117000000/116220000/116218200/116218186/49433449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/117000000/116220000/116218200/116218186/854f3349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/117000000/116220000/116218200/116218186/410949a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spanish Style 3 Story House, Best Location in SD. Views of North Park, W/ AC. North Park 4.8/10 (5) CA $414 CA $719 total includes taxes & fees Sep 30 - Oct 1 [](https://www.expedia.ca/San-Diego-Hotels-Spanish-Style-3-Story-House.h116218186.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101810000/101802700/101802668/61422d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/102000000/101810000/101802700/101802668/16d0f83d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/102000000/101810000/101802700/101802668/d579dd70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, video games, foosball](https://images.trvl-media.com/lodging/102000000/101810000/101802700/101802668/782a51d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### New! The Gem of Mission Hills: Luxury 5BR Home with Luxe Amenities and views" Mission Hills 9.6/10 Exceptional (23) "Every possible step that was needed to make our stay perfect...was done." [](https://www.expedia.ca/San-Diego-Hotels-New-Luxury-5BR-Home-W-Game-Room.h101802668.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/34000000/33710000/33703700/33703688/b88c5259.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/34000000/33710000/33703700/33703688/7cd5c03d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/34000000/33710000/33703700/33703688/488fd7cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, books, video library](https://images.trvl-media.com/lodging/34000000/33710000/33703700/33703688/61e54d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private 2-Bedroom Bungalow Bliss in North Park! Walking distance to everything! North Park 10/10 Exceptional (121) "Stayed at the property for 3 days, great neighborhood with plenty of options for things to do within walking/minimal driving distance. House was very clean, appreciated the ability to do laundry, etc. Owners were very quick with communication. Would recommend!" [](https://www.expedia.ca/San-Diego-Hotels-Private-2-Bedroom-Bungalow-Bliss-In-North-Park-Walking-Distance-To-Everything.h33703688.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/30e3d4c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/6dbb06e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/5fc3b001.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/107000000/106660000/106656300/106656297/e2add57c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Beautiful Normal Heights Living Mid-City 10/10 Exceptional (62) "Our stay here was great! The place was well equipped, within walking distance of great coffee and restaurants and had an easy check in / out process. " CA $345 CA $438 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/San-Diego-Hotels-Beautiful-Normal-Heights-Living.h106656297.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/34000000/33920000/33913000/33912914/b75002d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, toys, books](https://images.trvl-media.com/lodging/34000000/33920000/33913000/33912914/14227203.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, blackout drapes, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/34000000/33920000/33913000/33912914/c8416da9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/34000000/33920000/33913000/33912914/w1150h767x0y0-bd084921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### \*Charming\* Family & Couples Friendly 4 BR ENTIRE HOUSE Bankers Hill 9.4/10 Exceptional (56) "This was was the perfect setup for six of us! We were visiting San Diego for CRSSD, and it accommodated us perfectly. Very spacious, two bathrooms that were clean, and also two private parking spots was the huge win. I would definitely stay here again next year. " [](https://www.expedia.ca/San-Diego-Hotels-Charming-Family-Couples-Friendly-4-BR-Entire-House.h33912914.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/34000000/33510000/33504700/33504637/1d7257f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, travel crib](https://images.trvl-media.com/lodging/34000000/33510000/33504700/33504637/7bb64945.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/34000000/33510000/33504700/33504637/1c0f205d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/34000000/33510000/33504700/33504637/a30ae471.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Family Game Room with Wet Bar, Pool Table/ Ping Pong Darts and more! Linda Vista 9.8/10 Exceptional (174) "Perfect location for our trip" [](https://www.expedia.ca/San-Diego-Hotels-Family-Game-Room-With-Wet-Bar.h33504637.Hotel-Information) ![Outdoor dining](https://images.trvl-media.com/lodging/30000000/29670000/29668900/29668863/8c01bd89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/30000000/29670000/29668900/29668863/cebb6275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor spa tub](https://images.trvl-media.com/lodging/30000000/29670000/29668900/29668863/d5768b24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/30000000/29670000/29668900/29668863/7108e005.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Family Getaway ★ Pool & Hot-tub ★ HVAC ★ 4BD & Central Clairemont 9.8/10 Exceptional (149) "Great value great location." [](https://www.expedia.ca/San-Diego-Hotels-Family-Getaway-Pool-Hot-Tub-HVAC-4BD-Central.h29668863.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/32000000/31760000/31759400/31759318/9b460e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, DVD player, stereo](https://images.trvl-media.com/lodging/32000000/31760000/31759400/31759318/w1090h733x0y2-3227c821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/32000000/31760000/31759400/31759318/w1094h691x0y1-3f95aad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/32000000/31760000/31759400/31759318/w1085h713x0y5-747078ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxury 5BD/4BA Mission Hills/Stunning Rooftop + Skyline Views Mission Hills 9.4/10 Exceptional (205) "Very central location. Not a great area. Ali was great. " [](https://www.expedia.ca/San-Diego-Hotels-5BR-San-Diego-Villa-Private-Pool-Skyline-Views.h31759318.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100810000/100806300/100806236/440354c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/101000000/100810000/100806300/100806236/92aeb7ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100810000/100806300/100806236/630f489a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100810000/100806300/100806236/bdb3080c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Family Retreat-Full Kitchen✅10min-Zoo, Balboa Park✅Views✅BBQ✅Smart TV's✅Hot Tub Tierrasanta 10/10 Exceptional (43) "Nice, comfortable property with a very nice and helpful owner. " [](https://www.expedia.ca/San-Diego-Hotels-Family-Retreat1932ftBBQFull-KitchenBackyardViewsKingACWDSmart-TVs.h100806236.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/106000000/105510000/105500400/105500326/ceb67dd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/106000000/105510000/105500400/105500326/d9dd8528.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/106000000/105510000/105500400/105500326/9d10a449.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105510000/105500400/105500326/141b5119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super Spacious Family Vacation Home! Mira Mesa 9.6/10 Exceptional (22) "This home was a perfect place for our large group. There were plenty of beds and spaces to relax for our large group. The host was very responsive and the check in and check out processes were easy. " CA $586 CA $1,181 total includes taxes & fees Oct 5 - Oct 6 [](https://www.expedia.ca/San-Diego-Hotels-Super-Spacious-Family-Vacation-Home.h105500326.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/90000000/89800000/89796700/89796695/411fa398.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/90000000/89800000/89796700/89796695/d6cca75f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, books](https://images.trvl-media.com/lodging/90000000/89800000/89796700/89796695/b2536455.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89800000/89796700/89796695/46096074.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy 2Bed 1BA Bankers Hill Residence with Parking, no chores! Bankers Hill 9.4/10 Exceptional (39) "Great property! We came out for the Padres game and we took an uber from the house to the stadium. The backyard area is so beautiful and relaxing. Host was very responsive and friendly. Definitely coming back! " CA $356 CA $607 total includes taxes & fees Sep 25 - Sep 26 [](https://www.expedia.ca/San-Diego-Hotels-Cozy-2Bed-1BA-Bankers-Hill-Residence-With-Parking.h89796695.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/38000000/37010000/37009900/37009873/453d3e8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/38000000/37010000/37009900/37009873/d68b046e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/38000000/37010000/37009900/37009873/97fdd3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/38000000/37010000/37009900/37009873/314cb82e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Palisades By the Bay Whole House Rental Bay Ho 9.8/10 Exceptional (61) "Our family of 7 spent a week here. Plenty of room and we all enjoyed the pool. Plenty of games and entertainment for us to choose from. This property had easy access to all the attractions we wanted to see. Would highly recommend this home." [](https://www.expedia.ca/San-Diego-Hotels-Palisades-By-The-Bay-Whole-House-Rental.h37009873.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112110000/112101700/112101618/d8640865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/113000000/112110000/112101700/112101618/8cea26e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/113000000/112110000/112101700/112101618/05ab2245.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/113000000/112110000/112101700/112101618/d7e6283c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 2-bedroom apartment in terrific San Diego North Park Area with WiFi North Park 8.0/10 Very good (3) "Cute little apartment in close proximity to where we needed to be. The mop & bucket were left in the kitchen, there were no trash bags, no central air, no hand towels and the upstairs people were loud running back and forth at all times of the night. The beds were comfortable, the shower was good and all the appliances worked. Need more outlets in the kitchen. " CA $131 CA $351 total includes taxes & fees Oct 7 - Oct 8 [](https://www.expedia.ca/San-Diego-Hotels-Charming-2-Bedroom-Apartment-In-Terrific-San-Diego-North-Park-Area-With-WiFi.h112101618.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/117000000/116640000/116637700/116637613/5446fba0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/117000000/116640000/116637700/116637613/72ca415e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/117000000/116640000/116637700/116637613/5195c016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/117000000/116640000/116637700/116637613/f5dfe249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 5-bedroom house in San Diego with Games, BBQ, WiFi, AC Linda Vista 10/10 Exceptional (4) "The entire process from checking in to checking out was great! The host checked in on us to make sure we were enjoying our stay. Would definitely stay here again. " CA $366 CA $896 total includes taxes & fees Sep 24 - Sep 25 [](https://www.expedia.ca/San-Diego-Hotels-Spacious-5-Bedroom-House-In-San-Diego-With-Games.h116637613.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/98000000/97930000/97926300/97926248/e4d9561b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/98000000/97930000/97926300/97926248/9c9ff33a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/98000000/97930000/97926300/97926248/075eb18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/98000000/97930000/97926300/97926248/f719e424.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Modern Gem | Close to Downtown South Park 10/10 Exceptional (26) "Had a very special time with our family who live full time in your neighborhood, thanks." [](https://www.expedia.ca/San-Diego-Hotels-Modern-Gem-Close-To-Downtown.h97926248.Hotel-Information) ![Outdoor pool, a heated pool](https://images.trvl-media.com/lodging/105000000/104920000/104918000/104917977/203ca53d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104920000/104918000/104917977/w1755h1170x389y0-6c824888.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/105000000/104920000/104918000/104917977/c114adcb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/105000000/104920000/104918000/104917977/563713cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Entire home, Pool, Free Parking, WiFi, Pets are allowed Serra Mesa 8.8/10 Excellent (15) "Great Host, helped in a quickly manner and was amazing through out the stay." [](https://www.expedia.ca/San-Diego-Hotels-Entire-Home.h104917977.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-07&endDate=2025-10-08®ionId=6056570&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-San-Diego-Vacation-Rentals.d6056570.Travel-Guide-VacationRentals) ## Top Central San Diego Hotel Reviews ![Hilton Garden Inn San Diego Old Town/SeaWorld Area](//images.trvl-media.com/lodging/1000000/920000/919100/919096/ed62594a_y.jpg) ### Hilton Garden Inn San Diego Old Town/SeaWorld Area 10/10 Excellent "We are Hilton members as we can expect consistency with Hilton Hotels. The Taylor Street, San Diego location is perfect for walking to Old Town State Park, Mission Hills, and even up to Univ San Diego on the hill. The ONLY item missing on a hot day is available ice water (with lemon slices) in the lobby. I was directed to the Fitness Center for a cup of ice water. Otherwise we shall certainly book a room there next time we visit family in San Diego." [](https://expedia.ca/San-Diego-Hotels-Hilton-Garden-Inn-San-Diego-Old-TownSeaWorld-Area.h919096.Hotel-Information) ![Lafayette Hotel & Club](//images.trvl-media.com/lodging/39000000/38080000/38077800/38077738/91a184a3_y.jpg) ### Lafayette Hotel & Club 10/10 Excellent "Took my husband here for his bday. Felt like we were in Vegas. Dope experience! We didnt have to leave. Everything was there including a 24 hour diner! " [](https://expedia.ca/San-Diego-Hotels-Lafayette-Hotel.h38077738.Hotel-Information) ![San Diego Marriott La Jolla](//images.trvl-media.com/lodging/1000000/10000/2100/2097/05285107_y.jpg) ### San Diego Marriott La Jolla 10/10 Excellent "Love this hotel..coming back in november for my birthday lol" [](https://expedia.ca/La-Jolla-Hotels-San-Diego-Marriott-La-Jolla.h2097.Hotel-Information) ![The Atwood Hotel San Diego - SeaWorld/Zoo](//images.trvl-media.com/lodging/14000000/13160000/13155700/13155645/61eaf52a_y.jpg) ### The Atwood Hotel San Diego - SeaWorld/Zoo 10/10 Excellent "Just took a few days to myself for my 50th Birthday and everything was perfect. I broke my charger and was able to get one within minutes from the store on site. Lunch was perfect at the restaurant on site. The Jacuzzi was big enough that you never felt crowded. Within walking distance there was a nice spa and a really great Italian Steakhouse. I will definitely be returning soon." [](https://expedia.ca/San-Diego-Hotels-The-Atwood.h13155645.Hotel-Information) ![Hampton Inn San Diego/Mission Valley](//images.trvl-media.com/lodging/1000000/10000/4500/4415/036e1947_y.jpg) ### Hampton Inn San Diego/Mission Valley 10/10 Excellent "Front desk agent Brianna was friendly and helpful. Pool was nice. Room was clean " [](https://expedia.ca/San-Diego-Hotels-Hampton-Inn-San-Diego-Mission-Valley.h4415.Hotel-Information) ![Kings Inn San Diego](//images.trvl-media.com/lodging/1000000/20000/17000/16910/a5f26080_y.jpg) ### Kings Inn San Diego 10/10 Excellent "Great stay " [](https://expedia.ca/San-Diego-Hotels-Kings-Inn-San-Diego-Seaworld-Zoo.h16910.Hotel-Information) ![Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area](//images.trvl-media.com/lodging/1000000/100000/97900/97876/1d354139_y.jpg) ### Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area 10/10 Excellent "We enjoyed it" [](https://expedia.ca/San-Diego-Hotels-Homewood-Suites-By-Hilton-San-Diego-Hotel-CircleSeaWorld-Area.h97876.Hotel-Information) ![DoubleTree by Hilton San Diego - Hotel Circle](//images.trvl-media.com/lodging/1000000/30000/25600/25536/983f923b_y.jpg) ### DoubleTree by Hilton San Diego - Hotel Circle 10/10 Excellent "Clean room! Everything was nice! Great customer service !" [](https://expedia.ca/San-Diego-Hotels-DoubleTree-By-Hilton-San-Diego-Hotel-Circle.h25536.Hotel-Information) ![Country Inn & Suites by Radisson, San Diego North, CA](//images.trvl-media.com/lodging/1000000/20000/16600/16546/abd318f6_y.jpg) ### Country Inn & Suites by Radisson, San Diego North, CA 10/10 Excellent "Everything was great except the a/c unit did not work in our room. Luckily the weather was cooler but my pregnant wife wasn’t too happy as she prefers a colder room to sleep in." [](https://expedia.ca/San-Diego-Hotels-Country-Inn-Suites-By-Radisson.h16546.Hotel-Information) ## Find out more about Central San Diego **Everything you need to know about** **Central San Diego** **vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Central San Diego vacation rental for you. At Expedia, you can take your pick from [private vacation homes](https://www.expedia.ca/aa/PrivateVacationHomes), [apartments](https://www.expedia.ca/aa/Apartments), cottages, [cabins](https://www.expedia.ca/aa/Cabins), villas... The list goes on, and on… and on! There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Central San Diego vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.  **Central San Diego vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Central San Diego. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in .  Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Central San Diego vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Central San Diego vacation rentals we have selected for you start as low as CA $138 per night. Entering your travel dates in the search wizard you might find even better deals! **How to find incredible deals on Central San Diego rentals** At Expedia, we put the best Central San Diego vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.  To find some top Central San Diego rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Central San Diego vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Central San Diego. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.  ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca - All accommodation types in Central San Diego ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - 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Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)