Central Missouri Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Central Missouri Vacation

Whether you plan to visit Central Missouri for its rural countryside, spectacular views or something else entirely, this is one destination you'll never forget. Create your ultimate getaway with one of our Central Missouri vacation packages. With so much to see on a trip to Central Missouri, it can be tricky to know where to start. Kick off your journey in Columbia at Mizzou Arena and Columbia Mall — two much-loved attractions here. Another top city worth adding to your itinerary is Osage Beach. Don't miss Bagnell Dam and Lake of the Ozarks and Bagnell Dam Viewpoint. Find some travel buddies and start packing, because your Central Missouri vacation is only a few clicks away with Expedia.

Where to stay in Central Missouri

Find the best Central Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Central Missouri
Default Image

Shawnee Bend

While Shawnee Bend isn't home to many top sights, Gran Rally Karts and Osage Beach Premium Outlets are some notable places to visit nearby.

Find hotels in Shawnee Bend

Ready to book your vacation to Central Missouri?

 

Choose your dates

Central Missouri Hotel Deals

Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa

4 out of 5
315 Four Seasons Dr. Lake Ozark MO
Fully refundableReserve now, pay when you stay
The price is CA $126 per night from Jun 28 to Jun 29
CA $126
CA $170 total
Jun 28 - Jun 29
includes taxes & fees
7.4/10 Good! (1,171 reviews)
"The resort grounds are beautiful. The staff are very helpful and friendly."

Reviewed on Jun 16, 2026

Lodge Of Four Seasons Golf Resort, Marina & Spa
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

3 out of 5
494 Tan Tar A Drive Osage Beach MO
The price is CA $285 per night from Jun 21 to Jun 22
CA $285
CA $335 total
Jun 21 - Jun 22
includes taxes & fees
8.4/10 Very Good! (1,013 reviews)
"Wrong room, booked two queen and received a king. Third person had to sleep in rollaway bed. Carpets in hallway were filthy and musty smell in hallways"

Reviewed on Jun 13, 2026

Margaritaville Lake Resort Lake of the Ozarks
Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

4 out of 5
3100 Interstate 70 Dr. SE Columbia MO
Fully refundableReserve now, pay when you stay
The price is CA $146 per night from Jun 21 to Jun 22
CA $146
CA $164 total
Jun 21 - Jun 22
includes taxes & fees
9.6/10 Exceptional! (1,491 reviews)
"Room very clean and staff very courteous, friendly and professional."

Reviewed on Jun 14, 2026

Drury Plaza Hotel Columbia East
See all 5,116 properties in Central Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Stay near popular Central Missouri attractions

Lake of the Ozarks

Bagnell Dam

8.6/5 (519 reviews)
You can find out about the history of Lakeside with a trip to Bagnell Dam. Amble around this family-friendly area's lakeside and enjoy its top-notch restaurants.
See properties

Frequently asked questions

Can I cancel my flight booking to Central Missouri due to COVID-19?
Our handy Customer Service Portal has useful information about canceling or changing your flight due to COVID-19. Before booking, it's wise to check the terms and conditions of your airfare too.
What's the best way to find cheap flights to Central Missouri that have flexible change policies?
It's as easy as can be with Expedia. Firstly, enter your preferred travel dates and click "Search." Next, check the "No change fee" box directly under the "Flexible change policies" heading to the left of your screen. Step 3. Book your cheap and flexible airfare to Central Missouri.
What are some of the general tips for travelers to Central Missouri during the COVID-19 outbreak?
The COVID-19 outbreak may have changed how we travel, but it hasn't stopped our desire to explore. Here are some tips on how to navigate travel's new challenges:
  • Before locking in your flight, see if any travel bans or restrictions apply — in both your origin and destination. Keep informed with the latest updates by checking government and airport websites.
  • You're required to wear a face mask at the airport, including at screening checkpoints. Be prepared to lower your mask for ID purposes when asked by a TSA employee.
  • To reduce the likelihood of cross-contamination, place your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your pass directly to a TSA officer.
  • One liquid hand sanitizer container is now allowed in your carry-on luggage. It must be no bigger than 12 oz (350 ml), and you'll have to remove it from your bag for screening.
  • To minimize handling during the screening process, place personal items such as your phone, wallet and keys into your carry-on instead of the bins.
  • If you're planning to take food on the plane, put it in a clear plastic bag and then into a screening bin. This reduces the likelihood that a TSA employee will need to handle your carry-on bag or food container for inspection.

Which airlines fly to Central Missouri?
United Airlines operates flights into or near Central Missouri, including 52 that touch down at Cape Girardeau Municipal Airport (CGI) each month. Work out your travel dates and then secure your ticket early to score the best deal.
How can I find cheap tickets to Central Missouri?
To get your hands on a great deal to Central Missouri, book well ahead. Also consider using Expedia's handy "flexible dates" feature at the top of your search results. This will list prices for the days around your travel dates. In the last seven days, was the best price for a flight to Central Missouri.
How much is a flight to Central Missouri?
If you were jetting one way from (), you could've locked in a low-cost fare for in the last seven days. Return flights to Central Missouri ranged from to over the same period.
What are the most popular airports to fly into in Central Missouri?
Get ready to pack your suitcase and jet into Cape Girardeau Municipal Airport (CGI), Central Missouri's leading flight hub. Book a fare on one of the 52 flights that touch down at this top destination every month.
When is the cheapest time to fly to Central Missouri?
If you'd prefer to spend your vacation money exploring the delights of Central Missouri rather than on getting there, take off early in the week. The most affordable day to fly is usually Tuesday, with Monday coming in second. With many folks traveling on the weekend, Saturday typically has the highest ticket prices.
How much is a plane ticket to Central Missouri?
In the last seven days, airfares to Central Missouri varied between and . Prices usually rise as your travel date nears, so secure a terrific deal today.
Which airlines with flights to Central Missouri employ COVID-19 cleanliness policies?
Travel by plane now and you'll probably see that things have changed. For instance, most reputable carriers have implemented social distancing and improved hygiene standards. A couple of good examples are:
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.