Big Pine Key Vacation Rentals
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Browse Select Big Pine Key Vacation Homes

The Hammocks at Marathon
The Hammocks at Marathon
9.0 out of 10, Wonderful, (98)

Perla Blanca 4 Bed 5 Bath kayaks pool boat dock
Perla Blanca 4 Bed 5 Bath kayaks pool boat dock
9.8 out of 10, Exceptional, (48)

Manatee Bay , Pool table, Jacuzzi, Pool, Kayaks, REDUCED RATES AVAIL NOW<br>
Manatee Bay , Pool table, Jacuzzi, Pool, Kayaks, REDUCED RATES AVAIL NOW<br>
8.4 out of 10, Very good, (90)

Vacation with attitude!
Vacation with attitude!
10.0 out of 10, Exceptional, (7)

Oceanfront home-shared swimming pool, dockage-just 20 miles from Key West
Oceanfront home-shared swimming pool, dockage-just 20 miles from Key West
8.8 out of 10, Excellent, (86)
The price is CA $407
CA $957 total
includes taxes & fees
Aug 24 - Aug 25

Old Florida Style, wrap around porch, boat basin for dockage, open water
Old Florida Style, wrap around porch, boat basin for dockage, open water
9.6 out of 10, Exceptional, (77)

🌊 Private Oasis With Pool Spa Dock and Ocean right in your backyard 🌊 allow pets
🌊 Private Oasis With Pool Spa Dock and Ocean right in your backyard 🌊 allow pets
9.2 out of 10, Wonderful, (45)

Don't Miss This! Deep Water Canal, Swimspa Pool, Kayaks, Walk to Tiki Bars!!
Don't Miss This! Deep Water Canal, Swimspa Pool, Kayaks, Walk to Tiki Bars!!
10.0 out of 10, Exceptional, (78)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Big Pine Key Hotel Reviews

Rainbow Bend Resort
10/10 Excellent
Find out more about Big Pine Key
Find out more about Big Pine Key
Big Pine Key Vacation Homes information
Number of reviews | 819 |
---|---|
Accommodation | 1752 Vacation Homes |
Lowest Price | CA $407 |
Highest Price | CA $584 |
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Popular Destinations
Top Vacation Homes in Other Destinations
More Accommodation Types in Big Pine Key
- Condo Rentals in Big Pine Key
- Apartments in Big Pine Key
- Cottages in Big Pine Key
- Villas in Big Pine Key
- Aparthotels in Big Pine Key
- RV Parks in Big Pine Key
- Resorts in Big Pine Key
- Houseboats in Big Pine Key
- Cabin Rentals in Big Pine Key
- Motels in Big Pine Key
- B&B in Big Pine Key
- Lodges in Big Pine Key
- Hotels
All Accommodation Types
Be inspired: Top Vacation Homes destinations in 2025
- Orlando Vacation Homes
- Florida Vacation Homes
- Kissimmee Vacation Homes
- Hawaii Vacation Homes
- Costa Rica Vacation Homes
- Walt Disney World® Vacation Homes
- Palm Springs Vacation Homes
- Naples Vacation Homes
- Victoria Vacation Homes
- Kelowna Vacation Homes
- Toronto Vacation Homes
- Las Vegas Vacation Homes
- Vancouver Vacation Homes
- Mexico Vacation Homes
- Phoenix Vacation Homes
- Fort Lauderdale Vacation Homes
- Davenport Vacation Homes
- Myrtle Beach Vacation Homes
- Los Angeles Vacation Homes
- Cape Coral Vacation Homes
More ways to book
Expedia's Latest Trends
Hotels
- Best Hotels in Panama City Beach
- Best Hotels in St. Augustine
- Best Hotels in Key West
- Cocoa Beach Oceanfront Hotels
- Siesta Key Beach Hotel
- Best Hotels in Key Largo
- Best Hotels in Fort Myers Beach
- Key West All Inclusive Resorts and Hotels
- Best Hotels in Naples
- Best Hotels in Daytona Beach
- Best Hotels in Marco Island
- Best Hotels in West Palm Beach
- Best Hotels in Fort Myers
- Best Hotels in Sarasota
Flights
Activities
Packages
General