Cheap flights from Lafayette to San Diego from CA $122

View CA $122 flight on Thu, Sep. 4, 2025Opens in a new window

Popular airlines from Lafayette to San Diego

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Cheap flights from Lafayette (IND) to San Diego (SAN)

Prices were available within the past 7 days and start at CA $122 for one-way flights and CA $261 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Sep. 4 - Sun, Sep. 7
IND
Indianapolis
SAN
San Diego
CA $261 Roundtrip, found 2 days ago
CA $261
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep. 4 from Indianapolis to San Diego, returning Sun, Sep. 7, priced at CA $261 found 2 days ago
Spirit Airlines
Thu, Sep. 4 - Sun, Sep. 7
IND
Indianapolis
SAN
San Diego
CA $270 Roundtrip, found 2 days ago
CA $270
Roundtrip
found 2 days ago
Select Spirit Airlines flight, departing Thu, Sep. 4 from Indianapolis to San Diego, returning Sun, Sep. 7, priced at CA $270 found 2 days ago
American Airlines
Thu, Sep. 4 - Sun, Sep. 7
IND
Indianapolis
CLD
Carlsbad
CA $277 Roundtrip, found 2 days ago
CA $277
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep. 4 from Indianapolis to Carlsbad, returning Sun, Sep. 7, priced at CA $277 found 2 days ago
American Airlines
Thu, Sep. 4 - Sun, Sep. 7
IND
Indianapolis
SAN
San Diego
CA $277 Roundtrip, found 2 days ago
CA $277
Roundtrip
found 2 days ago
Select American Airlines flight, departing Thu, Sep. 4 from Indianapolis to San Diego, returning Sun, Sep. 7, priced at CA $277 found 2 days ago
Delta
Thu, Sep. 4 - Sun, Sep. 7
IND
Indianapolis
SAN
San Diego
CA $348 Roundtrip, found 2 days ago
CA $348
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Sep. 4 from Indianapolis to San Diego, returning Sun, Sep. 7, priced at CA $348 found 2 days ago
Alaska Airlines
Thu, Sep. 4 - Sun, Sep. 7
IND
Indianapolis
SAN
San Diego
CA $540 Roundtrip, found 2 days ago
CA $540
Roundtrip
found 2 days ago
Select Alaska Airlines flight, departing Thu, Sep. 4 from Indianapolis to San Diego, returning Sun, Sep. 7, priced at CA $540 found 2 days ago

Find the cheapest month to fly from Indianapolis (IND) to San Diego (SAN)

September is typically the cheapest month to fly

From CA $139 - CA $290 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.