Cheap flights from Buffalo to San Diego from CA $162

View CA $162 flight on Fri, Oct. 31, 2025Opens in a new window

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Cheap flights from Buffalo (BUF) to San Diego (SAN)

Prices were available within the past 7 days and start at CA $162 for one-way flights and CA $340 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Sep. 13 - Tue, Sep. 16
BUF
Buffalo
SAN
San Diego
CA $340 Roundtrip, found 19 hours ago
CA $340
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Sep. 13 from Buffalo to San Diego, returning Tue, Sep. 16, priced at CA $340 found 19 hours ago
American Airlines
Tue, Oct. 28 - Tue, Nov. 4
BUF
Buffalo
SAN
San Diego
CA $343 Roundtrip, just found
CA $343
Roundtrip
just found
Select American Airlines flight, departing Tue, Oct. 28 from Buffalo to San Diego, returning Tue, Nov. 4, priced at CA $343 just found
Delta
Thu, Nov. 13 - Tue, Nov. 18
BUF
Buffalo
SAN
San Diego
CA $377 Roundtrip, found 18 hours ago
CA $377
Roundtrip
found 18 hours ago
Select Delta flight, departing Thu, Nov. 13 from Buffalo to San Diego, returning Tue, Nov. 18, priced at CA $377 found 18 hours ago
Frontier Airlines
Fri, Oct. 3 - Sat, Oct. 18
BUF
Buffalo
SAN
San Diego
CA $382 Roundtrip, found 6 days ago
CA $382
Roundtrip
found 6 days ago
Select Frontier Airlines flight, departing Fri, Oct. 3 from Buffalo to San Diego, returning Sat, Oct. 18, priced at CA $382 found 6 days ago
JetBlue Airways
Thu, Nov. 13 - Tue, Nov. 18
BUF
Buffalo
SAN
San Diego
CA $382 Roundtrip, found 18 hours ago
CA $382
Roundtrip
found 18 hours ago
Select JetBlue Airways flight, departing Thu, Nov. 13 from Buffalo to San Diego, returning Tue, Nov. 18, priced at CA $382 found 18 hours ago
United
Sat, Sep. 13 - Tue, Sep. 16
BUF
Buffalo
SAN
San Diego
CA $478 Roundtrip, found 19 hours ago
CA $478
Roundtrip
found 19 hours ago
Select United flight, departing Sat, Sep. 13 from Buffalo to San Diego, returning Tue, Sep. 16, priced at CA $478 found 19 hours ago

Find the cheapest month to fly from Buffalo (BUF) to San Diego (SAN)

November is typically the cheapest month to fly

From CA $279 - CA $785 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.