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CA $187 Cheap Flights from Buffalo (BUF) to Des Moines (DSM)

View CA $187 flight on Tue, Sep 29, 2026Opens in a new window

Popular airlines from Buffalo Niagara Intl. Airport (BUF) to Des Moines International Airport (DSM)

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Cheap flights from Buffalo (BUF) to Des Moines (DSM)

Prices were available within the past 7 days and start at CA $187 for one-way flights and CA $373 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
DSM
Des Moines
CA $373 Roundtrip, found 1 day ago
CA $373
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to Des Moines, returning Tue, Oct 6, priced at CA $373 found 1 day ago
Delta
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
DSM
Des Moines
CA $373 Roundtrip, found 1 day ago
CA $373
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 29 from Buffalo to Des Moines, returning Tue, Oct 6, priced at CA $373 found 1 day ago
Delta
Sat, Aug 22 - Sat, Sep 5
BUF
Buffalo
DSM
Des Moines
CA $412 Roundtrip, found 1 day ago
CA $412
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 22 from Buffalo to Des Moines, returning Sat, Sep 5, priced at CA $412 found 1 day ago
Delta
Mon, Aug 31 - Fri, Sep 11
BUF
Buffalo
DSM
Des Moines
CA $413 Roundtrip, found 1 day ago
CA $413
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Aug 31 from Buffalo to Des Moines, returning Fri, Sep 11, priced at CA $413 found 1 day ago
American Airlines
Wed, Aug 12 - Fri, Aug 14
BUF
Buffalo
DSM
Des Moines
CA $425 Roundtrip, found 3 days ago
CA $425
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Aug 12 from Buffalo to Des Moines, returning Fri, Aug 14, priced at CA $425 found 3 days ago
American Airlines
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
DSM
Des Moines
CA $430 Roundtrip, found 1 day ago
CA $430
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 29 from Buffalo to Des Moines, returning Tue, Oct 6, priced at CA $430 found 1 day ago
Delta
Tue, Sep 29 - Tue, Oct 6
BUF
Buffalo
DSM
Des Moines
CA $438 Roundtrip, found 1 day ago
CA $438
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 29 from Buffalo to Des Moines, returning Tue, Oct 6, priced at CA $438 found 1 day ago
American Airlines
Wed, Aug 12 - Thu, Aug 13
BUF
Buffalo
DSM
Des Moines
CA $439 Roundtrip, found 3 days ago
CA $439
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Aug 12 from Buffalo to Des Moines, returning Thu, Aug 13, priced at CA $439 found 3 days ago
Delta
Mon, Aug 31 - Thu, Sep 17
BUF
Buffalo
DSM
Des Moines
CA $453 Roundtrip, found 1 day ago
CA $453
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Aug 31 from Buffalo to Des Moines, returning Thu, Sep 17, priced at CA $453 found 1 day ago
United
Thu, Aug 20 - Mon, Sep 7
BUF
Buffalo
DSM
Des Moines
CA $487 Roundtrip, found 1 day ago
CA $487
Roundtrip
found 1 day ago
Select United flight, departing Thu, Aug 20 from Buffalo to Des Moines, returning Mon, Sep 7, priced at CA $487 found 1 day ago

Alternative airports near Des Moines

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Des Moines Intl. DSM. Cheapest and Closest option available. Average driving time to city centre is 10 minutes. Flights from CA $641
DSM
Des Moines Intl.
CheapestClosest
Average driving time to city centre10 min
Flights from CA $641

Find the cheapest month to fly from Buffalo (BUF) to Des Moines (DSM)

February is typically the cheapest month to fly

From CA $373 - CA $672 per traveller.

Frequently asked questions

How much does a flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) cost?
You can find cheap one-way flights from CA $187 and cheap return flights from CA $373 BUF to DSM with Expedia. Return flights often range between CA$526 and CA$1336. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when BUF to DSM ticket fares go up or down.
What is the cheapest month to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The cheapest months to fly from BUF to DSM are typically during off-peak season when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you are able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Enter BUF to DSM and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Southwest Airlines is one of the cheapest airlines offering connecting return flights from Buffalo Niagara Intl. (BUF) to Des Moines Intl. (DSM), with prices starting from around CA$453 for flights that can be booked for departure within the next year. These flights typically include a layover in Baltimore Washington Intl. Thurgood Marshall (BWI). Prices are per adult for economy/coach class. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.
How do I find cheap flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
To find a cheap flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
There are approximately 39 connecting flights per day from Buffalo Niagara Intl. (BUF) to Des Moines Intl. (DSM). Some common connection points include O'Hare Intl. (ORD), Baltimore Washington Intl. Thurgood Marshall (BWI), and Washington Dulles Intl. (IAD).
What is the earliest flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The earliest flight from Buffalo Niagara International Airport (BUF) to Des Moines International Airport (DSM) typically departs around 5:00 AM local time. This flight is operated by American Airlines. This is a seasonal service, active in May. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
You'll typically find the most flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) on a Thursday, with around 25 flights available. This gives you a good selection of options for your travel plans. Major airlines on this route include United, American Airlines, and Delta. Flight schedules are fairly consistent throughout the week, so you'll have plenty of options no matter which day you choose to fly.
What are the most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The most popular departure times for flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) are in the early morning, from 6am to 9am. Many major carriers, including American Airlines, Delta and United, offer flights during this window. This timing works well because you can get an early start to your travel day and arrive in Des Moines with plenty of time.
How long does it take to fly from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
There are no nonstop flights from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.). The shortest flights typically involve one stop and take around 6 hours 30 minutes. Flights with two or more stops usually take longer, averaging about 9 hours 50 minutes. The distance between these two airports is approximately 1,236 kilometres. Keep in mind that actual flight times can vary due to factors like layover duration, routing, and weather conditions.
Can you fly business or first class from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
You can fly business class or first class between BUF and DSM. First class cabins are available on Delta, United, and American Airlines.
How do I earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight with Expedia?
It's easy to earn miles on a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Des Moines, IA (DSM) from Buffalo, NY (BUF)?
If you're planning to travel to Des Moines from Buffalo Niagara Intl. (BUF), you can fly directly into Des Moines Intl. (DSM). Some flights may connect through major hubs like Baltimore Washington Intl. Thurgood Marshall (BWI), Midway Intl. (MDW), or Washington Dulles Intl. (IAD) before reaching Des Moines. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) at the last minute?
Typically, booking a last minute flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package?
Securing a Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
If you booked your Buffalo, NY (BUF-Buffalo Niagara Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Buffalo Niagara Intl.
Destination airport
Des Moines Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
CA $373
Distance
1228 km

Book with confidence

Buffalo to Des Moines Flights

The easy way to book your flights from Buffalo to Des Moines 

With Expedia, it’s simple to find and book flights to Des Moines from Buffalo whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Des Moines Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Buffalo to Des Moines today, tomorrow, or this week.  

 

Save dollars with cheap flights from Buffalo Niagara Intl., BUF to Des Moines Intl., DSM 

Sort your search results by price to find great deals on your flight from Buffalo to Des Moines—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Des Moines from Buffalo currently is just CA $373 rising to CA $487.  

Here are more money-saving tips: 

  • Fly in September when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Des Moines  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Des Moines from Buffalo 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Des Moines with Expedia today.

Buffalo to Des Moines Flights

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*Available to Expedia members.