CA $165 Cheap Flights from Denver (DEN) to Des Moines (DSM)

View CA $165 flight on Sat, May 16, 2026Opens in a new window

Popular airlines from Denver International Airport (DEN) to Des Moines International Airport (DSM)

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Cheap flights from Denver (DEN) to Des Moines (DSM)

Prices were available within the past 7 days and start at CA $165 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

What is the cheapest month to fly from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
September is typically the cheapest month to fly from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.), with average round-trip fares of approximately 602 CAD. This is about 22% lower than the average price throughout the year. September often sees lower prices as the summer travel rush ends and before the holiday season begins, leading to reduced demand. Other cheap months to fly from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) include February and October.
Which airlines fly direct from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Enter DEN to DSM and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
To find a cheap flight from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best airline to fly with from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The best airline to fly with from Denver, CO (DEN-Denver Intl.) (DEN) to Des Moines, IA (DSM-Des Moines Intl.) (DSM) will differ from traveler to traveler. If you like to fly early, UA offers early morning flights. If price is the most important factor, F9 typically offers the lowest fares. WN offers the most daily flights from Denver, CO (DEN-Denver Intl.) (DEN) to Des Moines, IA (DSM-Des Moines Intl.) (DSM), which is great if flexibility is what you value most. The best carrier for this journey could also be the one you have a loyalty membership with, as flying with that airline or another airline within the same alliance could help you collect points or enjoy lounge access.
What is the best time to fly from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
When looking for the best time to fly from Denver International Airport (DEN) to Des Moines International Airport (DSM), you'll find that September and February are typically the cheapest months for a round-trip flight, with prices around 602 CAD. However, these don't overlap with the most popular travel times, which are October and July. If you're prioritizing savings, aim for September or February. This information is based on booking data from the past year.
How many flights per day from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
There are approximately 9 nonstop flights per day from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.). For even more choice, look at flights that include layovers, as there are around 109 connecting flights per day. Some common connection points include O'Hare Intl. (ORD), Minneapolis - St. Paul Intl. (MSP), and Dallas-Fort Worth Intl. (DFW).
What is the earliest flight from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The earliest flight from Denver, CO (DEN-Denver Intl.) (DEN) to Des Moines, IA (DSM-Des Moines Intl.) (DSM) typically departs at approximately 12:20 AM local time, operated by Delta Air Lines. This is a seasonal service active in January and December. An early departure like this can help maximize your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
You'll typically find the most flights from Denver Intl. (DEN) to Des Moines Intl. (DSM) on a Friday, with around 50 flights available. This gives you plenty of options for your travel plans. Major airlines on this route include United Airlines, American Airlines, and Southwest Airlines. Friday offers notably more flight options compared to other days of the week.
What are the most popular departure times for flights from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
The most popular departure times for flights from Denver Intl. (DEN) to Des Moines Intl. (DSM) are in the morning, between 9am and 12pm. About 25% of passengers prefer this time window. Many major carriers, including American Airlines, Delta Air Lines and Frontier Airlines, offer flights during this window. This timing works well because it allows you to start your travel day a bit later while still arriving at your destination with plenty of time left in the day.
How long does it take to fly from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Flying nonstop from DEN to DSM takes around 1 hour 50 minutes, with the route covering approximately 589 miles. Flights with a layover typically take 3 hours 40 minutes longer than direct options. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
Select the "Business class" and "First class" filters when looking for DEN to DSM flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight with Expedia?
It's easy to earn miles on a Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Des Moines from Denver Intl. (DEN)?
From Denver Intl. (DEN), you can fly directly into Des Moines Intl. (DSM) to reach Des Moines. Some flights may connect through major hubs like Wichita Dwight D. Eisenhower National (ICT), Cincinnati - Northern Kentucky Intl. (CVG), Kansas City Intl. (MCI) before reaching Des Moines. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) at the last minute?
Typically, booking a last minute flight from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package?
Securing a Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.)?
If you booked your Denver, CO (DEN-Denver Intl.) to Des Moines, IA (DSM-Des Moines Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Denver Intl.
Destination airport
Des Moines Intl.
Distance
941 km
Average flight time
2 hours 50 mins

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Denver to Des Moines Flights

The easy way to book your flights from Denver to Des Moines 

With Expedia, it’s simple to find and book flights to Des Moines from Denver whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Des Moines Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Denver to Des Moines today, tomorrow, or this week.  

 

Save dollars with cheap flights from Denver Intl., DEN to Des Moines Intl., DSM 

Sort your search results by price to find great deals on your flight from Denver to Des Moines—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Des Moines from Denver currently is just rising to .  

Here are more money-saving tips: 

  • Fly in when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Des Moines  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Des Moines from Denver 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Des Moines with Expedia today.

Denver to Des Moines Flights

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