Cheap flights from Mexico City to Santa Clara from CA $225

View CA $225 flight on Thu, Dec. 25, 2025Opens in a new window

Popular airlines from Mexico City to Santa Clara

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Cheap flights from Mexico City (MEX) to Santa Clara (SJC)

Prices were available within the past 7 days and start at CA $225 for one-way flights and CA $409 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Wed, Aug. 13 - Mon, Aug. 18
MEX
Mexico City
SFO
San Francisco
CA $409 Roundtrip, found 11 hours ago
CA $409
Roundtrip
found 11 hours ago
Select Aeromexico flight, departing Wed, Aug. 13 from Mexico City to San Francisco, returning Mon, Aug. 18, priced at CA $409 found 11 hours ago
Delta
Wed, Aug. 13 - Mon, Aug. 18
MEX
Mexico City
SFO
San Francisco
CA $409 Roundtrip, found 11 hours ago
CA $409
Roundtrip
found 11 hours ago
Select Delta flight, departing Wed, Aug. 13 from Mexico City to San Francisco, returning Mon, Aug. 18, priced at CA $409 found 11 hours ago
American Airlines
Fri, Sep. 19 - Mon, Sep. 22
MEX
Mexico City
SFO
San Francisco
CA $420 Roundtrip, found 6 days ago
CA $420
Roundtrip
found 6 days ago
Select American Airlines flight, departing Fri, Sep. 19 from Mexico City to San Francisco, returning Mon, Sep. 22, priced at CA $420 found 6 days ago
American Airlines
Wed, Aug. 13 - Mon, Aug. 18
MEX
Mexico City
SFO
San Francisco
CA $431 Roundtrip, found 11 hours ago
CA $431
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Wed, Aug. 13 from Mexico City to San Francisco, returning Mon, Aug. 18, priced at CA $431 found 11 hours ago
United
Sun, Aug. 31 - Sat, Sep. 6
MEX
Mexico City
SFO
San Francisco
CA $565 Roundtrip, found 17 hours ago
CA $565
Roundtrip
found 17 hours ago
Select United flight, departing Sun, Aug. 31 from Mexico City to San Francisco, returning Sat, Sep. 6, priced at CA $565 found 17 hours ago
Air Canada
Fri, Sep. 19 - Mon, Sep. 22
MEX
Mexico City
SFO
San Francisco
CA $956 Roundtrip, found 6 days ago
CA $956
Roundtrip
found 6 days ago
Select Air Canada flight, departing Fri, Sep. 19 from Mexico City to San Francisco, returning Mon, Sep. 22, priced at CA $956 found 6 days ago

Find the cheapest month to fly from Mexico City (MEX) to San Jose (SJC)

May is typically the cheapest month to fly

From CA $469 - CA $872 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.