Santa María Vacation Packages

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  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Your Santa María Vacation

When you book a Santa María vacation package, you can kick back and enjoy your escape to the fullest. Uncover the highlights of this fascinating city knowing that all the travel planning has been looked after before you go. San Jose Beach and Plaza de Armas are a couple of the must-see sights to visit during a trip to Santa María. No matter your travel plans or the size of your budget, putting together a tailored Santa María vacation is a breeze with Expedia.

Top Santa María Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Zielo Hotel

Zielo Hotel

3 out of 5
Price was CA $2,321, price is now CA $2,097 per person
CA $2,097
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asuncion (ASU)
9.4/10 Exceptional! (142 reviews)

Divina Tower

Divina Tower

4 out of 5
Recoleta
Price was CA $2,944, price is now CA $2,362 per person
CA $2,362
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asuncion (ASU)
9.4/10 Exceptional! (43 reviews)
The room, staff and service were amazing. The only little downside, the gym is no where close to a real gym.... its a closet. But wont hold that against the hotel. The rest makes up for it!

Reviewed on Oct 24, 2026

Nobile Suites Excelsior Asuncion

Nobile Suites Excelsior Asuncion

3 out of 5
Catedral
Price was CA $2,392, price is now CA $2,121 per person
CA $2,121
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asuncion (ASU)
8.6/10 Excellent! (289 reviews)

Hotel Guarani Asuncion

Hotel Guarani Asuncion

4 out of 5
Catedral
Price was CA $2,521, price is now CA $2,272 per person
CA $2,272
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asuncion (ASU)
8.6/10 Excellent! (654 reviews)
Fantastic place to be in room and bed comfy plus amazing breakfast

Reviewed on Oct 8, 2026

Oasis-Dream Holidays - La Petite France

Oasis-Dream Holidays - La Petite France

3 out of 5
Price was CA $2,513, price is now CA $2,271 per person
CA $2,271
per person
Dec 27 - Jan 3
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Asuncion (ASU)
9.6/10 Exceptional! (20 reviews)
Very helpful staff Nice amenities and clean rooms

Reviewed on Jul 17, 2026

Ready to book your vacation to Santa María?

 

Choose your dates

Santa María Hotel Deals

Sun Hotel

Sun Hotel

3.5 out of 5
Encarnacion Itapúa
The price is CA $98 per night from Oct 28 to Oct 29
CA $98
CA $108 total
Oct 28 - Oct 29
includes taxes & fees
8.8/10 Excellent! (167 reviews)
"Aceptable, por el valor esperaba un poquito mas!"

Reviewed on Oct 26, 2026

Sun Hotel
Carnaval Hotel Casino

Carnaval Hotel Casino

3.5 out of 5
Av. Irrazabal, 750 Encarnacion
Fully refundableReserve now, pay when you stay
The price is CA $100 per night from Nov 1 to Nov 2
CA $100
CA $110 total
Nov 1 - Nov 2
includes taxes & fees
9.4/10 Exceptional! (213 reviews)
"The best thing of the property was the Staff. They were accommodating and always asking you. How was your day very very friendly."

Reviewed on Sep 12, 2026

Carnaval Hotel Casino
Awa Resort Hotel

Awa Resort Hotel

4 out of 5
Ruta 1 Km 367, Calles Tajy y Naranjal Encarnacion
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Nov 27 to Nov 28
CA $127
CA $140 total
Nov 27 - Nov 28
includes taxes & fees
Awa Resort Hotel
See all 36 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Family Vacations
Family Vacations

Frequently asked questions

How much does a Santa María vacation package cost?
You can pick up a vacation package to this top destination from CA $2,097 on Expedia. But how much your vacation to Santa María costs will depend on factors like the length of stay, hotel choice and season.
What are the cheapest months to go to Santa María?
You're likely to find reduced prices and greater availability in January, February and April. Browse our cheap Santa María vacation packages and you could get some great off-season deals.
How many days is enough for Santa María?
Usually, a handful of days is enough to tick off the major sights during your Santa María vacation. However, if you prefer to have more time to kick back or go on day tours, think about extending your trip.
How to find the best Santa María package deals?
Use Expedia's filter tool to help you find some great Santa María package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your escape for midweek, or search for Santa María package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could land you great savings when compared to arranging flights and accommodations individually. Better still, you can customize your Santa María trip to match your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to Santa María?
If you're considering a spur-of-the-moment Santa María trip, check out our last-minute deals that can be booked up to a week before you take off. Prefer not to wait until the last minute? You can find terrific deals on your flights and hotels by booking ahead.
How to plan a trip to Santa María?

  1. Choose your dates: The things you'd like to do in Santa Marían and your favourite season will help you decide when to get away.
  2. Budget wisely: In addition to the price of your hotel, you'll need to consider other expenses. These include food, transportation and flights. Also, put aside some extra funds for unexpected expenses that may come up during your trip to Santa María.
  3. Work out your trip length: Think about how much time you want to spend exploring Santa María. Plan your itinerary so you can get to all the experiences and attractions you're interested in at a leisurely pace.
  4. Bundle your hotel and flights: Epic destination, check. Length of stay, check. All that's left now is to choose a Santa María vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.