Title: Santa Isabel Vacation Rentals from CA $105: Short-Term Rentals for 2026 | Expedia.ca

[Santa Isabel Travel Guide](https://expedia.ca/Santa-Isabel.dx6035096)[Hotels in Santa Isabel](https://expedia.ca/Santa-Isabel-Hotels.d6035096.Travel-Guide-Hotels)[Things to do in Santa Isabel](https://expedia.ca/Things-To-Do-In-Santa-Isabel.d6035096.Travel-Guide-Activities)[Santa Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Isabel.d6035096.Car-Rental-Guide)[Santa Isabel Vacation Packages](https://expedia.ca/Santa-Isabel.d6035096.Destination-Travel-Guides)

![Aerial view of Wind Turbines in the windfarm of Santa Isabel, Puerto Rico](https://images.trvl-media.com/place/6035096/238893ac-cef3-4b2d-be5e-72d5a4c1868f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/6035096/238893ac-cef3-4b2d-be5e-72d5a4c1868f.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.ca/Hotel-Search?regionId=6035096&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6035096&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.ca/Hotel-Search?regionId=6035096&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.ca/Hotel-Search?regionId=6035096&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Isabel vacation rentals

![Terrace/patio](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/0c933972.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/4c52eed0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Children's area](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/698d5478.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/124000000/123100000/123099800/123099733/ec25d784.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Casa Palma Serena - Garden Retreat • Tropical Stay

[](https://www.expedia.ca/Santa-Isabel-Hotels-Santa-Isabel.h123099733.Hotel-Information)

Santa Isabel

CA $175

CA $423 total

includes taxes & fees

Mar 4 - Mar 5

[](https://www.expedia.ca/Santa-Isabel-Hotels-Santa-Isabel.h123099733.Hotel-Information)

![On the beach](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/dee6afa1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/d6db4151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/8fd09926.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/121000000/120600000/120599000/120598921/1191238b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stunning Luxury Caribbean Villa – Ocean Views, Infinity Pool & Amazing Sunsets

[](https://www.expedia.ca/Santa-Isabel-Hotels-Amazing-Caribbean-Boho-Paradise-For-Couples.h120598921.Hotel-Information)

Santa Isabel

CA $422

CA $932 total

includes taxes & fees

Mar 3 - Mar 4

[](https://www.expedia.ca/Santa-Isabel-Hotels-Amazing-Caribbean-Boho-Paradise-For-Couples.h120598921.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/a475dadd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/a1d9b1f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/9f0e876a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/35000000/34330000/34325200/34325198/5a33ee5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cultural Oasis: Beachfront Gem, Puerto Rican Heritage at Your Doorstep

[](https://www.expedia.ca/Santa-Isabel-Hotels-Cultural-Oasis-Beachfront-Gem.h34325198.Hotel-Information)

Santa Isabel

8.8/10

Excellent

(45 reviews)

"It was amazing to be in the center of the culture. Friendly neighbors! Food amazing! Beach’s all around I would definitely stay there again!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Claudine N.

CA $272

CA $493 total

includes taxes & fees

Mar 5 - Mar 6

[](https://www.expedia.ca/Santa-Isabel-Hotels-Cultural-Oasis-Beachfront-Gem.h34325198.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/120000000/119880000/119870600/119870571/cb7b73b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/120000000/119880000/119870600/119870571/65d91bdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119880000/119870600/119870571/a5c02610.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/120000000/119880000/119870600/119870571/c2ceae52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Oceanfront Caribbean Escape – Infinity Pool +Interior Garden Sanctuary

[](https://www.expedia.ca/Santa-Isabel-Hotels-Oceanfront-Retreat-With-Private-Pool-Garden.h119870571.Hotel-Information)

Santa Isabel

9.6/10

Exceptional

(4 reviews)

"Such an amazing place. Views are spectacular. The outside family area was our favorite part. The pool was perfect too. My family and I were very comfortable here. Definitely look forward to coming back!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Selena R.

CA $347

CA $874 total

includes taxes & fees

Feb 19 - Feb 20

[](https://www.expedia.ca/Santa-Isabel-Hotels-Oceanfront-Retreat-With-Private-Pool-Garden.h119870571.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/3e731efe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/0a33b5fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/e1c1b42a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/116000000/115810000/115801600/115801590/9b169c3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Home in Santa Isabel, Puerto Rico. 4BR 2BA home with WiFi, AC & UNDERGROUND POOL

[](https://www.expedia.ca/Santa-Isabel-Hotels-Home-In-Santa-Isabel.h115801590.Hotel-Information)

Santa Isabel

10/10

Exceptional

(2 reviews)

"Our stay at Mimi’s VRBO was unforgettable, and we’re already planning our return! After searching for the ideal family rental, we chose Mimi’s listing and it was a game-changer. Her warmth and quick responses made everything seamless. When our flight was delayed, Mimi arranged a car to get us to the property and coordinated a rental car delivery the next morning.The house is a gem in a safe, friendly neighborhood, steps from Walmart and close to dining options. Packed with kid-friendly amenities...

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Henry S.

CA $367

CA $762 total

includes taxes & fees

Feb 19 - Feb 20

[](https://www.expedia.ca/Santa-Isabel-Hotels-Home-In-Santa-Isabel.h115801590.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/65ec3908.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/bb78e3e8_edited_4425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/e6ff84e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118310000/118309800/118309772/71cc332d_edited_73da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Coming and enjoy panoramic views to mountains and sea in Santa Isabel

[](https://www.expedia.ca/Santa-Isabel-Hotels-Coming-And-Enjoy-Panoramic-Views-To-Mountains-And-Sea-In-Santa-Isabel.h118309772.Hotel-Information)

Santa Isabel

CA $244

CA $461 total

includes taxes & fees

Feb 25 - Feb 26

[](https://www.expedia.ca/Santa-Isabel-Hotels-Coming-And-Enjoy-Panoramic-Views-To-Mountains-And-Sea-In-Santa-Isabel.h118309772.Hotel-Information)

![Deluxe Mobile Home | Living area](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/2fc3f8b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Mobile Home | Living area](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/3ffc6ff5_edited_0a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Cabin | Private kitchen](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/b1ed52e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Mobile Home](https://images.trvl-media.com/lodging/119000000/118220000/118212600/118212583/eaf5a63c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Gozadera Park

[](https://www.expedia.ca/Salinas-Hotels-La-Gozadera-Park.h118212583.Hotel-Information)

Salinas

CA $171

CA $186 total

includes taxes & fees

Mar 16 - Mar 17

[](https://www.expedia.ca/Salinas-Hotels-La-Gozadera-Park.h118212583.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/97345936.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room | In-room dining](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/370312d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room | Private kitchen](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/10c67684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium Room | Terrace/patio](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/6ecb708d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Place at the Sea

[](https://www.expedia.ca/Ponce-Hotels-The-Place-At-The-Sea.h83133987.Hotel-Information)

Ponce

9.4/10

Exceptional

(258 reviews)

"awesome place to stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

CHRISTOPHER A

CA $96

CA $105 total

includes taxes & fees

Feb 24 - Feb 25

[](https://www.expedia.ca/Ponce-Hotels-The-Place-At-The-Sea.h83133987.Hotel-Information)

![Deluxe Studio, Multiple Beds](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/44d9afe0_edited_9568.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Quadruple Room | Private kitchen](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/344e0f4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Standard Room | Private kitchen](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/76820cb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/8000000/7020000/7018800/7018767/14574c5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Playa Apartments

[](https://www.expedia.ca/Salinas-Hotels-Playa-Apartments.h7018767.Hotel-Information)

Salinas

7.6/10

Good

(37 reviews)

"Definitely clean, safe, user friendly place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JULIO

CA $171

CA $209 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Salinas-Hotels-Playa-Apartments.h7018767.Hotel-Information)

![Deluxe Room (201)](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377266/e3d81ba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room (201) | Bathroom sink](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377266/3d13e9cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room (201)](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377266/c31ac68d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/30000000/29380000/29377300/29377266/f722e28b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Aibonito Hotel 201

[](https://www.expedia.ca/Aibonito-Hotels-Aibonito-Hotel-201.h29377266.Hotel-Information)

Aibonito

7.0/10

Good

(31 reviews)

"Very good location and easy to find building. Nice and friendly staff."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

CA $170

CA $182 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Aibonito-Hotels-Aibonito-Hotel-201.h29377266.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/e1240d9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/d2e327ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/294858a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105460000/105454500/105454430/b12773ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy studio with private Pool and Bar modern amentities perfect for relaxation.

[](https://www.expedia.ca/Cidra-Hotels-Cozy-Studio-With-Private-Pool-And-Bar-Modern-Amentities-Perfect-For-Relaxation.h105454430.Hotel-Information)

Cidra

9.6/10

Exceptional

(4 reviews)

"We have a wonderful time! The pool and bar were perfect!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anna D.

CA $153

CA $349 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Cidra-Hotels-Cozy-Studio-With-Private-Pool-And-Bar-Modern-Amentities-Perfect-For-Relaxation.h105454430.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/b969b0ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/476e3102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/732def6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/110000000/109420000/109414600/109414598/b075f8cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Trinitarias Guest's House's pool/bar/karaoke/wifi

[](https://www.expedia.ca/Salinas-Hotels-Trinitarias-Guests-Houses-Poolbarkaraokewifi.h109414598.Hotel-Information)

Salinas

10/10

Exceptional

(2 reviews)

"Felt like home beautiful super clean quiet I will definitely be back to this home in our vacations Host is amazing Thank You for sharing this beautiful house with my family "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

julio

CA $134

CA $229 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Salinas-Hotels-Trinitarias-Guests-Houses-Poolbarkaraokewifi.h109414598.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/9be3e235.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/w1176h880x1y0-114edddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/cab1ca88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/111000000/110150000/110146400/110146312/w1177h1400x1y0-4ad24703.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy cabin with hot water jacuzzi and AC in the mountains of Guayama.

[](https://www.expedia.ca/Guayama-Hotels-Cozy-Cabin-With-Hot-Water-Jacuzzi-And-AC-In-The-Mountains-Of-Guayama.h110146312.Hotel-Information)

Guayama

10/10

Exceptional

(2 reviews)

"Property was so beautiful didn’t have any complains. Everything you need in one spot you’d never want to leave."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jonathan

CA $167

CA $266 total

includes taxes & fees

Feb 23 - Feb 24

[](https://www.expedia.ca/Guayama-Hotels-Cozy-Cabin-With-Hot-Water-Jacuzzi-And-AC-In-The-Mountains-Of-Guayama.h110146312.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/120000000/119550000/119547600/119547518/7d09fbcd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119550000/119547600/119547518/f7dd30b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/120000000/119550000/119547600/119547518/e58ba45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/120000000/119550000/119547600/119547518/173cc992.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3-bedroom house in Coamo with AC on bedroom 1

[](https://www.expedia.ca/Coamo-Hotels-3-Bedroom-House-In-Coamo-With-AC.h119547518.Hotel-Information)

Coamo

7.0/10

Good

(6 reviews)

"The house was nice ,comfortable and community was quiet and safe. we will be back..."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kenny R.

CA $62

CA $159 total

includes taxes & fees

Feb 18 - Feb 19

[](https://www.expedia.ca/Coamo-Hotels-3-Bedroom-House-In-Coamo-With-AC.h119547518.Hotel-Information)

![Outdoor spa tub](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/0dd88a14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/e8b56baf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/ac57be0e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/106000000/105140000/105136600/105136565/30034394_edited_4c62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### HW Tiny Home Cidra

[](https://www.expedia.ca/Cidra-Hotels-HW-Tiny-Home-Cidra.h105136565.Hotel-Information)

Cidra

10/10

Exceptional

(2 reviews)

"Beautiful area, great AC, clean hot tub, lovely acces to lake with paddleboat!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth C.

CA $159

CA $257 total

includes taxes & fees

Feb 16 - Feb 17

[](https://www.expedia.ca/Cidra-Hotels-HW-Tiny-Home-Cidra.h105136565.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/d8c8add6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/b6162ac3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, bed sheets](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/w904h683x60y0-97d3020c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/93000000/92030000/92024300/92024256/90054a0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Grandpa's lake house lake private access mountain view museum 1950's experience

[](https://www.expedia.ca/Cidra-Hotels-Grandpas-Lake-House-Lake-Private-Access-Mountain-View-Museum-1950s-Experience.h92024256.Hotel-Information)

Cidra

9.4/10

Exceptional

(6 reviews)

"We had a great peaceful visit!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kelly N.

CA $95

CA $158 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Cidra-Hotels-Grandpas-Lake-House-Lake-Private-Access-Mountain-View-Museum-1950s-Experience.h92024256.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/3d9cee92.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/77d0048f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/316a3102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/101000000/100440000/100431200/100431141/c7e903af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Oasis Salinas 

[](https://www.expedia.ca/Salinas-Hotels-Oasis-Salinas.h100431141.Hotel-Information)

Salinas

7.8/10

Good

(13 reviews)

"Excellent place to stay near everything in town "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mayra

CA $129

CA $187 total

includes taxes & fees

Feb 22 - Feb 23

[](https://www.expedia.ca/Salinas-Hotels-Oasis-Salinas.h100431141.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/9f98081f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/4c9dfd88.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/5b4d65ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/122000000/121890000/121880300/121880267/28313f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Nostra Casa Vagón

[](https://www.expedia.ca/Villalba-Hotels-Nostra-Casa-Vagon.h121880267.Hotel-Information)

Coamo

10/10

Exceptional

(1 review)

"Everything was very clean and organized I got confused with the address and the owner communicated with me and directed me to the exact address when I go to Puerto Rico again I will contact them again to stay at the same place "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carlos Reyes

CA $86

CA $190 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Villalba-Hotels-Nostra-Casa-Vagon.h121880267.Hotel-Information)

![Exterior detail](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/7172bbbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/c647e3ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, WiFi](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/b68c7819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/96000000/95990000/95987400/95987315/cd2da947.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### RED LOFT VIBE WALKING DISTANCE TO THE CITY

[](https://www.expedia.ca/Guayama-Hotels-RED-LOFT-VIBE-WALKING-DISTANCE-TO-THE-CITY.h95987315.Hotel-Information)

Guayama

9.6/10

Exceptional

(5 reviews)

"The best place to spend your days if you visit the city of Guayama, easy access to all the sites of interest in the area."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hector

CA $95

CA $158 total

includes taxes & fees

Feb 17 - Feb 18

[](https://www.expedia.ca/Guayama-Hotels-RED-LOFT-VIBE-WALKING-DISTANCE-TO-THE-CITY.h95987315.Hotel-Information)

![Comfort Studio | Living area](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/e2e46050.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Studio](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/81e5fad2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Studio | Private kitchen](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/627fd90b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Studio | Living area](https://images.trvl-media.com/lodging/30000000/29380000/29377200/29377164/eab5838c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chandelier 301

[](https://www.expedia.ca/Ponce-Hotels-Chandelier-301.h29377164.Hotel-Information)

Ponce Centro

7.0/10

Good

(8 reviews)

"Great stay if you are touring the area. Very secured spot and close to a lot of places. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Luis

CA $168

CA $217 total

includes taxes & fees

Feb 19 - Feb 20

[](https://www.expedia.ca/Ponce-Hotels-Chandelier-301.h29377164.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-27&endDate=2026-02-28&regionId=6035096&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

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## Find vacation rentals that suit your style

Aparthotels

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=APART_HOTEL)

Villas

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=VILLA)

Apartments

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=APARTMENT)

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=VACATION_HOME)

Cabins

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=CABIN)

Cottages

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=COTTAGE)

Condos

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=CONDO)

Chalets

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Puerto+Rico&regionId=6035096&latLong=17.966085%2C-66.404896&adults=2&startDate=2026-05-13&d1=2026-05-13&endDate=2026-05-16&d2=2026-05-16&lodging=CHALET)

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## Top Santa Isabel Hotel Reviews

![Holiday Inn Ponce & Tropical Casino by IHG](https://images.trvl-media.com/lodging/1000000/30000/21700/21613/45986a24_y.jpg)

### Holiday Inn Ponce & Tropical Casino by IHG

10/10 Excellent

"Todo super bien"

[](https://expedia.ca/Ponce-Hotels-Holiday-Inn-Ponce-Tropical-Casino.h21613.Hotel-Information)

![Hotel Las Vegas](https://images.trvl-media.com/lodging/29000000/28800000/28799500/28799456/abeca2f0_y.jpg)

### Hotel Las Vegas

10/10 Excellent

"This place is fantastic! The setup, the details, the staff.... everything was wonderful"

[](https://expedia.ca/Santa-Isabel-Hotels-Motel-Las-Vegas.h28799456.Hotel-Information)

![Hilton Ponce Golf & Casino Resort](https://images.trvl-media.com/lodging/1000000/10000/6400/6322/456e16ff_y.jpg)

### Hilton Ponce Golf & Casino Resort

10/10 Excellent

"No me gusto que no me incluyeron el desayuno en la estadia."

[](https://expedia.ca/Ponce-Hotels-Hilton-Ponce-Golf-Casino-Resort.h6322.Hotel-Information)

![Hotel El Eden](https://images.trvl-media.com/lodging/29000000/28810000/28800500/28800460/b1a506e9_y.jpg)

### Hotel El Eden

10/10 Excellent

"Everything was amazing. Staff was wonderful. They clean the room whenever you need them to clean it. It was nice and clean. And I will recommend."

[](https://expedia.ca/Juana-Diaz-Hotels-Motel-El-Eden.h28800460.Hotel-Information)

![The Place at the Sea](https://images.trvl-media.com/lodging/84000000/83140000/83134000/83133987/97345936_y.jpg)

### The Place at the Sea

10/10 Excellent

"Excelente "

[](https://expedia.ca/Ponce-Hotels-The-Place-At-The-Sea.h83133987.Hotel-Information)

![Ponce Plaza Hotel & Casino](https://images.trvl-media.com/lodging/3000000/2840000/2836400/2836309/ab1ae408_y.jpg)

### Ponce Plaza Hotel & Casino

10/10 Excellent

"Amazing staff. Great location. Super clean and modern. Great amenities and comfortable facilities. "

[](https://expedia.ca/Ponce-Hotels-Ponce-Plaza-Hotel-Casino.h2836309.Hotel-Information)

![Hotel Nuevo Mejico](https://images.trvl-media.com/lodging/28000000/27660000/27656400/27656340/42430f9d_y.jpg)

### Hotel Nuevo Mejico

10/10 Excellent

"Room was clean and great service. "

[](https://expedia.ca/Ponce-Hotels-Motel-Nuevo-Mejico.h27656340.Hotel-Information)

![1912 Boutique Hotel](https://images.trvl-media.com/lodging/120000000/119160000/119157000/119156926/35a18024_y.jpg)

### 1912 Boutique Hotel

10/10 Excellent

"Real nice room"

[](https://expedia.ca/Cayey-Hotels-1912-Boutique-Hotel.h119156926.Hotel-Information)

![Caribe Hotel Ponce](https://images.trvl-media.com/lodging/1000000/970000/969600/969532/726a9194_y.jpg)

### Caribe Hotel Ponce

10/10 Excellent

"Room, staff and breakfast amazing!!"

[](https://expedia.ca/Ponce-Hotels-Spark-By-Hilton-Ponce.h969532.Hotel-Information)

## Find out more about Santa Isabel

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santa Isabel. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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## Frequently asked questions

### Are there vacation rentals in Santa Isabel?

### What's the top vacation rental that Santa Isabel has to offer?

### How many vacation rentals will I find in Santa Isabel?

### What can I see and do in Santa Isabel?

### What are vacation rentals like in Santa Isabel?

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