Title: Book The Best Hotels in Santa Isabel for 2026 from CA $283 - Fully Refundable Options - Expedia.ca

[Vacation Rentals in Santa Isabel](https://expedia.ca/Santa-Isabel-Vacation-Rentals.d6203540.Travel-Guide-VacationRentals)[Santa Isabel Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Isabel.d6203540.Car-Rental-Guide)[Santa Isabel Vacation Packages](https://expedia.ca/Santa-Isabel.d6203540.Destination-Travel-Guides)

![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

# Find hotels in Santa Isabel from CA $283

- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg)  
###  
Change your mind  
Book hotels with free cancellation
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg)  
###  
Treat yourself  
Sign in to save 10% or more on thousands of hotels  
[Sign in](https://www.expedia.ca/login)
- ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg)  
###  
Be picky  
Search almost a million properties worldwide

## Go beyond your typical stay in Santa Isabel

Ocean view

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Col%C3%B3n%2C+Panama&regionId=6203540&latLong=9.539417%2C-79.195937&adults=2&startDate=2026-01-11&d1=2026-01-11&endDate=2026-01-13&d2=2026-01-13&amenities=OCEAN_VIEW)

House­boat

[](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel%2C+Col%C3%B3n%2C+Panama&regionId=6203540&latLong=9.539417%2C-79.195937&adults=2&startDate=2026-01-11&d1=2026-01-11&endDate=2026-01-13&d2=2026-01-13&lodging=HOUSE_BOAT)

## Check prices for these dates

Tonight

[Dec 28 - Dec 29](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2025-12-28&endDate=2025-12-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Dec 29 - Dec 30](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2025-12-29&endDate=2025-12-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Jan 9 - Jan 11](https://www.expedia.ca/Hotel-Search?regionId=6203540&startDate=2026-01-09&endDate=2026-01-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Santa Isabel hotels

![Aerial view](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/7a4cf19e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Room, 2 Double Beds | Garden view](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/1cc9d52d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/1370ba19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/519a6b1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  San Blas Paradise Private Cabins on Shipwreck Island - meals included

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Perro-Island.h37804534.Hotel-Information)

Narganá

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Perro-Island.h37804534.Hotel-Information)

![Panoramic Cabin, Ocean View | Beach/ocean view](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/w2878h1920x0y0-df17b8ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/caaaab49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/7708eca7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Private Ocean-Front Cabin with private bathroom on San Blas Island

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information)

Narganá

CA $257

CA $283 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/9e5e20c9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/w576h935x0y0-5a1d7985.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Bungalow](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/c36bcffd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Economy Bungalow](https://images.trvl-media.com/lodging/104000000/103730000/103726800/103726734/w714h952x0y0-03c55ba8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Trips Guna Yala

[](https://www.expedia.ca/Nargana-Hotels-Trips-Guna-Yala.h103726734.Hotel-Information)

Narganá

CA $138

CA $326 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/Nargana-Hotels-Trips-Guna-Yala.h103726734.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/1b4156f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/5ebfc967.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Free WiFi](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/7fd698a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/96000000/95810000/95807400/95807391/a3e9a150.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cocoloco - Catamaran Lagoon 52F SAN BLAS

[](https://www.expedia.ca/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information)

Narganá

CA $2,618

CA $2,887 total

includes taxes & fees

Jan 11 - Jan 12, 2026

[](https://www.expedia.ca/Nargana-Hotels-Cocoloco-Catamaran-Lagoon-52F-SAN-BLAS.h95807391.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/10dee59f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/ceab5053.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/eb4eaf61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Cabin](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/ec710209.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabins in Asserya Island - San Blas paradise - meals included

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Aroma-Island.h37744686.Hotel-Information)

Narganá

[](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Aroma-Island.h37744686.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/8fa7ada5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Shared Dormitory](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/f8b34eb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/e2771f8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/38000000/37830000/37822600/37822583/1f4d85cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabins on paradise San Blas island

[](https://www.expedia.ca/Carti-Hotels-Cabins-In-Tuba-Senika-Island.h37822583.Hotel-Information)

Narganá

[](https://www.expedia.ca/Carti-Hotels-Cabins-In-Tuba-Senika-Island.h37822583.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-11&endDate=2026-01-12&regionId=6203540&adults=2&sort=RECOMMENDED&openPlayBack=true)

![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg)

Save an average of 15% on thousands of hotels when you're signed in

[Sign in

](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d6203540.Travel-Guide-Hotels)[

Sign up, it's free

](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Hotels.d6203540.Travel-Guide-Hotels)

## More cheap stays in Santa Isabel

![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/ede84b95_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Private Ocean-Front Cabin with private bathroom on San Blas Island

Diablo Island Narganá Guna Yala

CA $257

CA $283 total

Dec 29 - Dec 30

includes taxes & fees

[](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information)

![ San Blas Paradise Private Cabins on Shipwreck Island - meals included](https://images.trvl-media.com/lodging/38000000/37810000/37804600/37804534/7a4cf19e_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

###  San Blas Paradise Private Cabins on Shipwreck Island - meals included

Perro Island Narganá Guna Yala

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F01%2F2026&endDate=12%2F01%2F2026&selected=37804534&PinnedHotelID=37804534&HadPinnedHotel=true&regionId=6203540)

[](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Perro-Island.h37804534.Hotel-Information)

![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Private Over the Water Cabin on San Blas Island

9.542876, -78.899058 Narganá San Blas

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F01%2F2026&endDate=12%2F01%2F2026&selected=37715808&PinnedHotelID=37715808&HadPinnedHotel=true&regionId=6203540)

7/10 Good! (6 reviews)

[](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information)

![Cabins in Asserya Island - San Blas paradise - meals included](https://images.trvl-media.com/lodging/38000000/37750000/37744700/37744686/10dee59f_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Cabins in Asserya Island - San Blas paradise - meals included

Aroma Island (Isla Anzuelo) Narganá Guna Yala

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F01%2F2026&endDate=12%2F01%2F2026&selected=37744686&PinnedHotelID=37744686&HadPinnedHotel=true&regionId=6203540)

[](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Aroma-Island.h37744686.Hotel-Information)

![ Paradise Over the Water Cabins in San Blas](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/fe0394dd_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

###  Paradise Over the Water Cabins in San Blas

G4V2 48 Narganá Guna Yala

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F01%2F2026&endDate=12%2F01%2F2026&selected=46948372&PinnedHotelID=46948372&HadPinnedHotel=true&regionId=6203540)

[](https://expedia.ca/El-Porvenir-Hotels-Newly-Built-Paradise-Cabins-In-San-Blas.h46948372.Hotel-Information)

![Private wood Cabins on San Blas island - private bathroom](https://images.trvl-media.com/lodging/38000000/37750000/37743100/37743019/b9c5df53_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Private wood Cabins on San Blas island - private bathroom

Wailidup Island Narganá Guna Yala

[Get rates](https://expedia.ca/Hotel-Search?startDate=11%2F01%2F2026&endDate=12%2F01%2F2026&selected=37743019&PinnedHotelID=37743019&HadPinnedHotel=true&regionId=6203540)

[](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Wailidup-Island.h37743019.Hotel-Information)

## Recent reviews of Santa Isabel hotels

![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg)

### Private Over the Water Cabin on San Blas Island

5/5 Excellent

"Very nice. And I liked the food "

A verified traveller stayed at Private Over the Water Cabin on San Blas Island

Posted 5 months ago

[](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information)

## Frequently asked questions

### What's the best place to stay in Santa Isabel?

### What are some of the best vacation home rentals that Santa Isabel has to offer?

### If I need to cancel my hotel reservation in Santa Isabel, will I receive a refund?

### What is staying in Santa Isabel like?

### What are the top places to visit in Santa Isabel?

### What's the seasonal weather like in Santa Isabel?

## Explore a world of travel with Expedia

- Lodging
- Packages
- Cars

- [La Guaira Hotels ](https://www.expedia.ca/La-Guaira-Hotels.d3000439511.Travel-Guide-Hotels)
- [Nombre de Dios Hotels ](https://www.expedia.ca/Nombre-De-Dios-Hotels.d3000462548.Travel-Guide-Hotels)
- [Palenque Hotels ](https://www.expedia.ca/Palenque-Hotels.d553248623282267036.Travel-Guide-Hotels)
- [Playa Chiquita Hotels ](https://www.expedia.ca/Playa-Chiquita-Hotels.d553248635975847835.Travel-Guide-Hotels)

- [Palenque Vacations ](https://www.expedia.ca/Palenque.d553248623282267036.Destination-Travel-Guides)

- [Car rental Miramar ](https://www.expedia.ca/Car-Rentals-In-Miramar.d553248623282266307.Car-Rental-Guide)

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app