Name: La Perla Hotel
Price range: CA $107

Your Santa Cruz Vacation

There's no better way to get away than with one of our vacation packages to Santa Cruz. The lively atmosphere and beaches are two of the countless reasons to spend some time in this awesome city. A trip to Santa Cruz is an ideal opportunity to do some sightseeing. Be sure to stop by renowned attractions like Lapostolle Clos Apalta Winery, Laura Hartwig Winery and Casino Colchagua. Your perfect Santa Cruz vacation is a couple of clicks away. Browse airfares, hotels and more on Expedia for an adventure that's tailored just for you.

Top Santa Cruz Vacation Deals

Price found within the past 48 hours. Click for updated prices.

Hotel Capital Bellet

Providencia

CA $863

per person

Oct 6 - Oct 11

found 1 hour ago

Roundtrip flight included

Montreal (YUL) to Santiago (SCL)

9/10 Wonderful! (755 reviews)

The hotel is good, I will return in the future.

Reviewed on Aug. 20, 2025

ICON Hotel

Las Condes

CA $980

per person

Oct 6 - Oct 11

found 1 hour ago

Roundtrip flight included

Montreal (YUL) to Santiago (SCL)

8.6/10 Excellent! (1,001 reviews)

Location and excellent costumer service.

Reviewed on Aug. 22, 2025

Hotel Eco Boutique Bidasoa

Vitacura

CA $1,486

per person

Nov 16 - Nov 22

found 20 hours ago

Roundtrip non-stop flight included

Toronto (YYZ) to Santiago (SCL)

9.2/10 Wonderful! (227 reviews)

Excelente hotel. Definitivamente voy a volver. Lo único que me gustaría que fuese distinto es la pileta: es bastante chica y no es climatizada (además de externa). Todo lo demás, realmente muy bueno y recomendable. Destaco particularmente el profesionalismo y amabilidad del personal.

Reviewed on Aug. 9, 2025

Renaissance Santiago Hotel by Marriott

Vitacura

CA $1,297

per person

Oct 6 - Oct 11

found 1 hour ago

Roundtrip flight included

Montreal (YUL) to Santiago (SCL)

9/10 Wonderful! (360 reviews)

Great. Nightclub Wednesday’s also

Reviewed on Jul. 14, 2025

Mandarin Oriental, Santiago

Las Condes

CA $1,896

per person

Nov 16 - Nov 22

found 20 hours ago

Roundtrip non-stop flight included

Toronto (YYZ) to Santiago (SCL)

9.2/10 Wonderful! (888 reviews)

Very convenient location. Beautiful views to the mountains

Reviewed on Aug. 31, 2025

Ready to book your vacation to Santa Cruz?

Choose your dates

Santa Cruz Hotel Deals

Santa Cruz Plaza

Plaza De Armas 286, Santa Cruz, O'Higgins

Fully refundableReserve now, pay when you stay

CA $168

CA $168 total

Sep 14 - Sep 15

TerraViña

Camino Los Boldos S/n, Santa Cruz, O'Higgins

Fully refundableReserve now, pay when you stay

CA $156

CA $156 total

Sep 1 - Sep 2

La Perla Hotel

El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins

CA $107

CA $107 total

Sep 1 - Sep 2

See all 53 properties in Santa Cruz

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.