Southern Region Vacations & Trips 2026

Photo by Kalunde Mbevi

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Your Southern Region Vacation

When adventure calls, answer it with a tailor-made vacation package to Southern Region. Wherever it is you're headed and whatever you have planned, prepare to discover a destination that'll make you truly feel alive. Your trip to Southern Region wouldn't be complete without spending some time in its best cities, starting with Blantyre. A couple of the top attractions here include Mandala House and Carlsberg Brewery. Zomba is another favourite city with Southern Region travellers. Visitors to this city enjoy Emperor's View and Williams Falls. Expedia has everything you need when it comes to organizing your Southern Region vacation. From flights and hotels, to activities and more, we know how to create a travel experience like no other.

Top vacation destinations in Southern Region

A cityscape at dusk with a prominent building in the center, surrounded by residential areas and a mountain in the background.

Southern Region Hotel Deals

Protea Hotel by Marriott Blantyre Ryalls

2 Hannover Avenue Blantyre

Fully refundableReserve now, pay when you stay

CA $204

CA $242 total

Sep 5 - Sep 6

includes taxes & fees

8.8/10 Excellent! (151 reviews)

"The restaurant was excellent! The staff was friendly and so helpful when I arranged a dinner for 20 people. A special shoutout of thanks to Sanderson, the amazing gentleman who helped me plan the event!"

Reviewed on Aug 23, 2026

Casa Mia

Kabula Hill Road Blantyre

CA $139

CA $164 total

Sep 1 - Sep 2

includes taxes & fees

Anake Lodge

Chembe Village Cape Maclear Southern Region

CA $76

CA $91 total

Sep 1 - Sep 2

includes taxes & fees

See all 107 properties in Southern Region

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Southern Region vacation package cost?

Choose from any combination of flights, hotels and car rentals, and you can be vacationing in Southern Region from just . And the more you bundle, the more cash you save. Your dream vacation has never been so affordable.

How do I get a cheap travel package to Southern Region?

Our Southern Region vacation packages mean plenty of savings for the savvy traveler. For the best deals, simply bundle your flights, hotels and extras (such as activities) into one neat package. But low prices are just the beginning of your next big adventure. Book with Expedia and and you'll have over 550 air carriers and 1,000,000 hotel options all over the world to choose from. Whatever your budget or style, there's a vacation package to suit you.

What are the top hotels in Southern Region?

When it comes to properties in Blantyre, Protea Hotel by Marriott Blantyre Ryalls and Malawi Sun Hotel & Conference Centre are two fantastic options. If you're also spending time in Mangochi, Casa Mia and Hotel Victoria will make you feel at home.

How far in advance should I book my Southern Region vacation?

It's always wise to book early. Air carriers usually advertise flight tickets up to 12 months ahead of departure, and this is an ideal opportunity to pick up some of the lowest prices. Just been told you need to take all your vacation days in a few weeks? Don't fret. Expedia are never short of fantastic deals to whisk you away on the getaway of your dreams, at an affordable price.

What does an Expedia Southern Region travel package include?

Choose from a combination of hotels, flights and rental cars. Once you've made your booking, you can add experiences and tours. Want to pick your airfare class? That's easily done too. The choice is all yours when it comes to organizing your ideal Southern Region getaway.

What should I know before booking a Southern Region travel package?

A package can be easier on the bank balance than individually booking all you need for your trip. For example, bundle your hotels, flights and rental cars and score impressive savings. Whatever your vacation goals are, you're bound to find a package that matches your budget.

Can I choose my airline with a Southern Region Expedia vacation package?

You can. We offer more than 550 airline partners around the world, so fly with the carrier that suits your needs.

If I'm not able to travel, can I cancel my Southern Region vacation package?

If your travel plans in Southern Region have been upended, it's good to know that it's possible to cancel your booking. If you made your booking less than 24 hours ago, you may be able to receive a refund. If your booking is older than that, your airline, hotel or car rental company may impose fees. For more details, visit our Customer Service Portal.

Stay near popular Southern Region attractions

Monkey Bay Beach

8.6/10 (4 reviews)

If a restful vacation is part of your travel plans, Monkey Bay Beach might be the perfect place to seek out during your trip to Mangochi. Take in the museums while you're in the area.

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