Title: Eastern Panama Vacation Rentals from CA $148: Short-Term Rentals for 2026 | Expedia.ca [Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides) ![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Nico Barner ![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 19 - Jun 21](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 17 - Jul 19](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Eastern Panama vacation rentals ![Property grounds](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/99016f78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/f4818252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/ba1656e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/4c6cabd5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Private Beach Cabin [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information) Narganá [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information) ![Boating](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/fad9e47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/edcd0ecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin | Beach/ocean view](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/8b5aa11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/1c15e003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Private Oceanfront Cabin [](https://www.expedia.ca/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information) Narganá CA $355 CA $528 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information) ![Dock](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/533ab64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/4091b21d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/749003b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/c2647d0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Over-Water Cabins on San Blas Island [](https://www.expedia.ca/San-Blas-Islands-Hotels-Prvt-Beach-Cabins-In-San-Blas-Islands.h46949355.Hotel-Information) Narganá CA $287 CA $453 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Prvt-Beach-Cabins-In-San-Blas-Islands.h46949355.Hotel-Information) ![Basic Cabin, Ocean View | Beach](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/db3e2027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Ocean View | Property grounds](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/aacdaacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Ocean View | Exterior](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/a8dab923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Ocean View | Beach](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/w3056h3853x0y0-a025e370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanblastourgy [](https://www.expedia.ca/Nargana-Hotels-Sanblastourgy.h124417283.Hotel-Information) Nargana CA $344 CA $378 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Nargana-Hotels-Sanblastourgy.h124417283.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/1649bd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/4fd01df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/7ad3ced9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/07d64ddb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabaña La Punta op het Strand!! [](https://www.expedia.ca/Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information) Colón Province CA $178 CA $233 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/a6aae70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/fef7062f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/9f704818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Despierta sobre el mar [](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) Garrote 6.0/10 (1 review) CA $103 CA $148 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) ![Basic Cabin, Multiple Beds, Balcony, Sea View | Beach/ocean view](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/5e4a77e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Multiple Beds, Balcony, Sea View | Bathroom](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/0c7c55ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/4f1afbb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/e1ca9c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Tour Aridub [](https://www.expedia.ca/San-Blas-Tour-Aridub.h107987054.Hotel-Information) Narganá CA $117 CA $198 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/San-Blas-Tour-Aridub.h107987054.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/803cd264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/9304c3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/1b7d8cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/c41bafb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Catamaran experience in paradise [](https://www.expedia.ca/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information) Guna Yala Comarca CA $794 CA $1,269 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information) ![Beach nearby, beach towels](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/a2a99590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/da467749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/07d1058d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/6f230b81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Exclusive sailboat for 2 people all inclusive in San Blas islands [](https://www.expedia.ca/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information) Guna Yala 10/10 Exceptional (1 review) "Anita e Federico sono state il valore aggiunto in queste isole meravigliose. La loro disponibilita, le loro attenzioni, i sorridenti contatti di Anita con la popolazione dei Guna e la cucina superlativa di Federico hanno reso speciale la nostra vacanza che ha soddisfatto appieno le nostre aspettative. Discreta e deliziosa la presenza della gattina (la principessa di bordo) Shanu. Grazie di tutto!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Grazia B. CA $727 CA $832 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/1c2dafbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, 2 Double Beds, Ocean View, Overwater | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/2e9ab169.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![On the beach, white sand](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/633fd22f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, 2 Double Beds, Ocean View, Overwater](https://images.trvl-media.com/lodging/47000000/46950000/46948400/46948372/0564bbf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Paradise Over the Water Cabins in San Blas [](https://www.expedia.ca/El-Porvenir-Hotels-Newly-Built-Paradise-Cabins-In-San-Blas.h46948372.Hotel-Information) Narganá 6.0/10 (1 review) "29/22 i stay with my family for three nights and 4 days the beds are not comfortable and the fan doesn't work the bathroom need cleaning, the worst part is the sandflyies we got bitten all over our bodies, the owners can do better with proper new nets and fan and maybe spray the place, after the first night we want to leave so bad. The island is not so bad its peaceful and claim but after the bites we could take it we were prepared with bug spray but it was not enough for the bugs. The island... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dominik [](https://www.expedia.ca/El-Porvenir-Hotels-Newly-Built-Paradise-Cabins-In-San-Blas.h46948372.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/0b910251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, stovetop, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/bb4bcbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/3d134b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/6da56f2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama [](https://www.expedia.ca/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information) Guna Yala Comarca CA $1,084 CA $1,277 total includes taxes & fees Apr 3 - Apr 4 [](https://www.expedia.ca/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/14bad027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/30f0b989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/551ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deluxe Beachfront 4-bedroom house in Colón Province [](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) Colón Province CA $465 CA $530 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/fa337c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/e6b8f41d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/93d05a41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/d70c8750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private cabin in San Blas [](https://www.expedia.ca/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information) Panama , Betania CA $364 CA $414 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information) ![Boating](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/b3b793d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/d29880fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/268dce26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/8e470218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Private Over-the-Water Cabin [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Over-The-Water-Cabin.h46949679.Hotel-Information) Narganá 8.0/10 Very good (2 reviews) "I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Over-The-Water-Cabin.h46949679.Hotel-Information) ![On the beach, sun loungers, beach towels](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/w1064h805x0y11-7ae51d02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/5a781682_edited_8afc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books, stereo](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/ad3a9028.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/75000000/74060000/74054900/74054867/252623d6_edited_e05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### BEAUTIFUL APARTMENT IN FRONT OF THE SEA [](https://www.expedia.ca/Portobelo-Hotels-BEAUTIFUL-APARTMENT-IN-FRONT-OF-THE-SEA.h74054867.Hotel-Information) Portobelo 8.0/10 Very good (3 reviews) "All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rosa M. CA $215 CA $244 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Portobelo-Hotels-BEAUTIFUL-APARTMENT-IN-FRONT-OF-THE-SEA.h74054867.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/1f45d7b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, cookware/dishes/utensils](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/38938e50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/743536b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/d2331d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jacuzy, pool and lake at the same house. [](https://www.expedia.ca/Nueva-Providencia-Hotels-Jacuzy.h45022806.Hotel-Information) Colon 6.0/10 (2 reviews) "Great. Please take care of the cat" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KENNETH E. CA $47 CA $95 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Nueva-Providencia-Hotels-Jacuzy.h45022806.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/eefeb662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/46b29819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast meal](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/23dccb12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/bc739ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming cottage with 2 separate beds and a beautiful view of the river [](https://www.expedia.ca/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information) Santa Rosa 10/10 Exceptional (1 review) "Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank." ![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg) Birgit U. CA $173 CA $200 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/9bf6774d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/bde6b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/23785068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/ac93b6ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita [](https://www.expedia.ca/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information) Maria Chiquita 6.8/10 (3 reviews) "Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Will CA $124 CA $199 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/3d98011b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/e05e8ef5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/7123cf2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114700000/114691500/114691452/a0ff3f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Elegance and comfort in old town panama [](https://www.expedia.ca/24-De-Diciembre-Hotels-Vrbo-Property.h114691452.Hotel-Information) Panamá CA $69 CA $124 total includes taxes & fees Mar 24 - Mar 25 [](https://www.expedia.ca/24-De-Diciembre-Hotels-Vrbo-Property.h114691452.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/f538191e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/617e1c47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/e8dc67fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/115000000/114230000/114220300/114220227/bae0d59a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquil cabin with WiFi in Los Altos de Cerro Azul [](https://www.expedia.ca/Caimitillo-Hotels-Tranquil-Cabin-With-WiFi-In-Los-Altos-De-Cerro-Azul.h114220227.Hotel-Information) Los Altos de Cerro Azul CA $206 CA $280 total includes taxes & fees Mar 25 - Mar 26 [](https://www.expedia.ca/Caimitillo-Hotels-Tranquil-Cabin-With-WiFi-In-Los-Altos-De-Cerro-Azul.h114220227.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-06&endDate=2026-04-07®ionId=6246114&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Apartments [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=APARTMENT) Villas [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=VILLA) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=CABIN) Condos [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=CONDO) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=VACATION_HOME) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=COTTAGE) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-06-21&d1=2026-06-21&endDate=2026-06-24&d2=2026-06-24&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals) ## Top Eastern Panama Hotel Reviews ![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/a23e7585_y.jpg) ### Private Ocean-Front Cabin with private bathroom on San Blas Island 10/10 Excellent "Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. " [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-In-Diablo-Island.h37766985.Hotel-Information) ![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/9a39b281_y.jpg) ### Ordovician Beach Resort 10/10 Excellent "The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed." [](https://expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information) ![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/fedfb071_y.jpg) ### Ranchos de Chalia 10/10 Excellent "Amazing location, beautiful vistas of mountains, forest and ocean. Very relaxing environment with infinity pool. Well maintained grounds. Wonderful breakfast and dinners. Jose and Anna were amazing hosts. Marijka and Garth" [](https://expedia.ca/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) ![Konsenda San Blas](https://images.trvl-media.com/lodging/100000000/99080000/99079700/99079675/5ba2b554_y.jpg) ### Konsenda San Blas 10/10 Excellent "Great location for bird watching! The hosts were friendly and helpful. It is best to contact them directly using WhatsApp in addition to booking on Expedia." [](https://expedia.ca/El-Llano-Hotels-Konsenda-San-Blas.h99079675.Hotel-Information) ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg) ### HOTEL ISLA GRANDE 4/10 Poor "This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces." [](https://expedia.ca/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information) ![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/272cbe65_y.jpg) ### Ciel y Miel 10/10 Excellent "The views from this mountain-top boutique hotel are extraordinary." [](https://expedia.ca/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) ## Find out more about Eastern Panama You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded. As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Eastern Panama. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do. ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca - All accommodation types in Eastern Panama ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals) - 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