Title: Visit Eastern Panama: Best of Eastern Panama Tourism | Expedia Travel Guide - Expedia.ca [Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides) # Eastern Panama ## Travel Guide ![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![A Kuna Yala man headed out to fish. If you have ever dreamed of spending a night or two on a small, private island, check out Kuna Yala. If you don't like roughing it a little bit, this might not be for you. There are cabins with flushing toilets but no electricity and the shower water is rather cool. Great place to get away from crowds and unplug though. #islands #peaceful #Adventure #water #ocean #boat #trovember](https://images.trvl-media.com/place/6246376/d3a402eb-8cb8-4f70-9be6-1b7fe662551a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![A definite bucketlist place to visit if ever in #Panama. #SanBlas](https://images.trvl-media.com/place/6246376/a6346c00-8b9f-4941-bebd-cae3909ada84.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Secluded island in the Guna Yala region of Panama](https://images.trvl-media.com/place/829297845969362944/4b998afd-12f7-4a39-bbc7-d387cdb43caf.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Eastern Panama Things to do - Eastern Panama Hotel Deals - Vacation Rentals in Eastern Panama ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL ISLA GRANDE Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province CA $142 CA $156 total Feb 2 - Feb 3 includes taxes & fees Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National ... 4.8/10 (5 reviews) Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting ... Reviewed on Sep 19, 2025 [](https://expedia.ca/Hotel-Search?startDate=02%2F02%2F2026&endDate=03%2F02%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6246114) ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cocotal La Guaira Isla Grande Provincia de Colón Fully refundableReserve now, pay when you stay CA $81 CA $149 total Feb 19 - Feb 20 includes taxes & fees Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ... 9.4/10 Exceptional! (6 reviews) Excelente hospedaje lo mejor la amabilidad de José Ángel y los demás muchachos... Con decirles que hasta te llevan a la habitación si te has tomado algunos tragos.. recomendada al 100 Reviewed on Jan 7, 2026 [](https://expedia.ca/Hotel-Search?startDate=19%2F02%2F2026&endDate=20%2F02%2F2026&selected=116789972&PinnedHotelID=116789972&HadPinnedHotel=true®ionId=6246114) ![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Ranchos de Chalia Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón CA $158 CA $176 total Feb 9 - Feb 10 includes taxes & fees Stay at this hotel in Puerto Lindo. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Isla Mamey and Portobelo National Park are located ... 9.6/10 Exceptional! (13 reviews) Beautiful tranquility in nature, amazing staff Reviewed on Nov 23, 2025 [](https://expedia.ca/Hotel-Search?startDate=09%2F02%2F2026&endDate=10%2F02%2F2026&selected=105443903&PinnedHotelID=105443903&HadPinnedHotel=true®ionId=6246114) [See all 178 properties in Eastern Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=02%2F02%2F2026&endDate=03%2F02%2F2026®ionId=6246114) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Over the Water Cabin on San Blas Island 9.542876, -78.899058 Narganá San Blas Book a stay at this beach cabin in San Blas Islands. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Isla Chichime ... 7/10 Good! (6 reviews) Very nice. And I liked the food Reviewed on Aug 14, 2025 [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ![San Blas Private Beach Cabin](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/a97a9ec2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Private Beach Cabin Nusatupo Narganá Guna Yala Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ... [](https://expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information) ![Caribbean getaway: beach cottage just on the sand](https://images.trvl-media.com/lodging/72000000/71150000/71150000/71149949/24e34d16_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Caribbean getaway: beach cottage just on the sand Palenque Provincia de Colón Book a stay at this beach cottage in Palenque. Enjoy free WiFi, a beach locale, and a garden. 10/10 Exceptional! (1 review) The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. Reviewed on Oct 15, 2025 [](https://expedia.ca/Palenque-Hotels-Caribbean-Getaway-Beach-Cottage-Just-On-The-Sand.h71149949.Hotel-Information) [See all properties in Eastern Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6246114&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Eastern Panama hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-02-01&endDate=2026-02-02)[Feb 1 - Feb 2](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-02-01&endDate=2026-02-02) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-02-02&endDate=2026-02-03)[Feb 2 - Feb 3](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-02-02&endDate=2026-02-03) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026)[Feb 6 - Feb 8](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=06%2F02%2F2026&endDate=08%2F02%2F2026) ### Popular places to visit ![Secluded island in the Guna Yala region of Panama](https://images.trvl-media.com/place/829297845969362944/4b998afd-12f7-4a39-bbc7-d387cdb43caf.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Isla Diablo Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.ca/Isla-Diablo-Nargana.d951034527519002624.Vacation-Attraction) #### Isla Chichime Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.ca/Isla-Chichime-Nargana.d951034147716386816.Vacation-Attraction) #### Museum of the Kuna Nation You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals. [](https://expedia.ca/Museum-Of-The-Kuna-Nation-San-Blas-Islands.d553248621579133546.Vacation-Attraction) ## Cities near Eastern Panama ![Islands of San Blas , Panama; Shutterstock ID 687617053; Purchase Order: -](https://images.trvl-media.com/place/6024116/aba78afe-1be5-4d43-bdc0-318dfbedec76.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### San Blas Islands ![A beautiful national park.](https://images.trvl-media.com/place/829297769735790592/2e588f90-6c14-4e79-b26f-399114dcb4eb.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Caimitillo ![One of the 365 islands that represent San Blas in Panama. The majority of these islands are inhabited, some of them has the size of various football fields, while others are only a few square meters with one or two palm trees on it. ](https://images.trvl-media.com/place/6246376/d1b147ce-530c-4046-ae1d-41f25eb2f34a.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Narganá - Cities near Eastern Panama - Places of interest [San Blas Islands](https://expedia.ca/San-Blas-Islands.dx6024116)[Tupile](https://expedia.ca/Tupile.dx553248635963618492)[Carti](https://expedia.ca/Carti.dx553248635974498100)[Mandinga](https://expedia.ca/Mandinga.dx553248635975856894)[Camogantí](https://expedia.ca/Camoganti.dx829297382853201920)[Paya](https://expedia.ca/Paya.dx829297452726095872)[Púcuro](https://expedia.ca/Pucuro.dx829297458059177984)[Boca de Cupe](https://expedia.ca/Boca-De-Cupe.dx829297466781212672)[Yape](https://expedia.ca/Yape.dx829297475935293440)[El Real de Santa María](https://expedia.ca/El-Real-De-Santa-Maria.dx829297481505312768)[Pinogana](https://expedia.ca/Pinogana.dx829297485225668608)[Yaviza](https://expedia.ca/Yaviza.dx829297489688424448)[Metetí](https://expedia.ca/Meteti.dx829297497563209728)[Manuel Ortega](https://expedia.ca/Manuel-Ortega.dx829297506843123712)[Cirilo Guainora](https://expedia.ca/Cirilo-Guainora.dx829297515193970688)[Lajas Blancas](https://expedia.ca/Lajas-Blancas.dx829297526369701888)[Río Iglesias](https://expedia.ca/Rio-Iglesias.dx829297548421255168)[Agua Fría](https://expedia.ca/Agua-Fria.dx829297553955622912)[Cañita](https://expedia.ca/Canita.dx829297618541613056)[Las Margaritas](https://expedia.ca/Las-Margaritas.dx829297622907908096)[Tortí](https://expedia.ca/Torti.dx829297631527182336)[Caimitillo](https://expedia.ca/Caimitillo.dx829297769735790592)[Puerto Obaldía](https://expedia.ca/Puerto-Obaldia.dx829297796248002560)[Tubualá](https://expedia.ca/Tubuala.dx829297812280709120)[Ailigandí](https://expedia.ca/Ailigandi.dx829297826484744192) - [Cayos Holandeses ](https://expedia.ca/Cayos-Holandeses-Guna-Yala.d553248621579133545.Vacation-Attraction) - [Isla Mamey ](https://expedia.ca/Isla-Mamey-Colon.d553248623454093160.Vacation-Attraction) - [Colon Free Zone ](https://expedia.ca/Colon-Free-Zone-Barrio-Sur.d6078503.Vacation-Attraction) - [Chagres National Park ](https://expedia.ca/Chagres-National-Park-Panama.d6252818.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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