Title: Visit Eastern Panama: Best of Eastern Panama Tourism | Expedia Travel Guide - Expedia.ca [Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Vacation Rentals in Eastern Panama](https://expedia.ca/Eastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides) # Eastern Panama ## Travel Guide ![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![A Kuna Yala man headed out to fish. If you have ever dreamed of spending a night or two on a small, private island, check out Kuna Yala. If you don't like roughing it a little bit, this might not be for you. There are cabins with flushing toilets but no electricity and the shower water is rather cool. Great place to get away from crowds and unplug though. #islands #peaceful #Adventure #water #ocean #boat #trovember](https://images.trvl-media.com/place/6246376/d3a402eb-8cb8-4f70-9be6-1b7fe662551a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![A definite bucketlist place to visit if ever in #Panama. #SanBlas](https://images.trvl-media.com/place/6246376/a6346c00-8b9f-4941-bebd-cae3909ada84.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![Secluded island in the Guna Yala region of Panama](https://images.trvl-media.com/place/829297845969362944/4b998afd-12f7-4a39-bbc7-d387cdb43caf.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ![One of the 365 islands that represent San Blas in Panama. The majority of these islands are inhabited, some of them has the size of various football fields, while others are only a few square meters with one or two palm trees on it. ](https://images.trvl-media.com/place/6246376/d1b147ce-530c-4046-ae1d-41f25eb2f34a.jpg?impolicy=fcrop&w=1040&h=580&q=mediumHigh) ## Visit Eastern Panama Things to do - Eastern Panama Hotel Deals - Vacation Rentals in Eastern Panama ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### HOTEL ISLA GRANDE Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province Book a stay at this beach hotel in Isla Grande. Enjoy free breakfast, a beach locale, and onsite spa services. Popular attractions Isla Mamey and Portobelo National ... 4.8/10 (8 reviews) This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces. Reviewed on Feb 4, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=04%2F04%2F2026&endDate=05%2F04%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6246114) [](https://expedia.ca/Hotel-Search?startDate=04%2F04%2F2026&endDate=05%2F04%2F2026&selected=119947185&PinnedHotelID=119947185&HadPinnedHotel=true®ionId=6246114) ![Private Ocean-Front Cabin with private bathroom on San Blas Island](https://images.trvl-media.com/lodging/38000000/37770000/37767000/37766985/a23e7585_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Ocean-Front Cabin with private bathroom on San Blas Island Diablo Island Narganá Guna Yala Stay at this hotel in San Blas Islands. Enjoy free breakfast, an airport shuttle (surcharge), and a garden. Popular attractions Isla Diablo and Isla Chichime ... 10/10 Exceptional! (1 review) Staff was wonderful. Room was basic, as described. Basically camping on the beach with a comfortable bed. Fall asleep to ocean waves just feet from the door. Reviewed on Mar 15, 2026 [Get rates](https://expedia.ca/Hotel-Search?startDate=04%2F04%2F2026&endDate=05%2F04%2F2026&selected=37766985&PinnedHotelID=37766985&HadPinnedHotel=true®ionId=6246114) [](https://expedia.ca/Hotel-Search?startDate=04%2F04%2F2026&endDate=05%2F04%2F2026&selected=37766985&PinnedHotelID=37766985&HadPinnedHotel=true®ionId=6246114) ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Cocotal La Guaira Isla Grande Provincia de Colón CA $81 CA $150 total Apr 19 - Apr 20 includes taxes & fees Stay at this hotel in Isla Grande. Enjoy free breakfast, free WiFi, and 20 restaurants. Popular attractions Isla Mamey and Portobelo National Park are located ... [](https://expedia.ca/Hotel-Search?startDate=19%2F04%2F2026&endDate=20%2F04%2F2026&selected=116789972&PinnedHotelID=116789972&HadPinnedHotel=true®ionId=6246114) [See all 178 properties in Eastern Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=22%2F03%2F2026&endDate=23%2F03%2F2026®ionId=6246114) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![San Blas Private Beach Cabin](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/99016f78_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Private Beach Cabin Nusatupo Narganá Guna Yala Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ... [](https://expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information) ![San Blas Private Oceanfront Cabin](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/fad9e47a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### San Blas Private Oceanfront Cabin C5W9 4M Nusatupo Narganá Guna Yala Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). [](https://expedia.ca/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information) ![Private Over-Water Cabins on San Blas Island](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/533ab64d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Private Over-Water Cabins on San Blas Island C5W9 4M Nusatupo Narganá Book a stay at this beach cabin in Narganá. Enjoy free breakfast, a beach locale, and an airport shuttle (surcharge). Popular attractions Museum of the Kuna ... [](https://expedia.ca/San-Blas-Islands-Hotels-Prvt-Beach-Cabins-In-San-Blas-Islands.h46949355.Hotel-Information) [See all properties in Eastern Panama](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=6246114&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Eastern Panama hotel availability [Tonight ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-03-21&endDate=2026-03-22)[Mar 21 - Mar 22](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-03-21&endDate=2026-03-22) [Tomorrow night ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-03-22&endDate=2026-03-23)[Mar 22 - Mar 23](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=2026-03-22&endDate=2026-03-23) [Next weekend ](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026)[Mar 27 - Mar 29](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=6246114&startDate=27%2F03%2F2026&endDate=29%2F03%2F2026) ### Popular places to visit ![Secluded island in the Guna Yala region of Panama](https://images.trvl-media.com/place/829297845969362944/4b998afd-12f7-4a39-bbc7-d387cdb43caf.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Isla Diablo Commune with nature and explore the great outdoors at Isla Diablo during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.ca/Isla-Diablo-Nargana.d951034527519002624.Vacation-Attraction) #### Isla Chichime Commune with nature and explore the great outdoors at Isla Chichime during your travels in San Blas Islands. Take in the festivals while you're in the area. [](https://expedia.ca/Isla-Chichime-Nargana.d951034147716386816.Vacation-Attraction) #### Museum of the Kuna Nation You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals. [](https://expedia.ca/Museum-Of-The-Kuna-Nation-San-Blas-Islands.d553248621579133546.Vacation-Attraction) ## Cities near Eastern Panama ![Islands of San Blas , Panama; Shutterstock ID 687617053; Purchase Order: -](https://images.trvl-media.com/place/6024116/aba78afe-1be5-4d43-bdc0-318dfbedec76.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### San Blas Islands ![A beautiful national park.](https://images.trvl-media.com/place/829297769735790592/2e588f90-6c14-4e79-b26f-399114dcb4eb.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Caimitillo ![One of the 365 islands that represent San Blas in Panama. The majority of these islands are inhabited, some of them has the size of various football fields, while others are only a few square meters with one or two palm trees on it. ](https://images.trvl-media.com/place/6246376/d1b147ce-530c-4046-ae1d-41f25eb2f34a.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Narganá - Cities near Eastern Panama - Places of interest [San Blas Islands](https://expedia.ca/San-Blas-Islands.dx6024116)[Tupile](https://expedia.ca/Tupile.dx553248635963618492)[Carti](https://expedia.ca/Carti.dx553248635974498100)[Mandinga](https://expedia.ca/Mandinga.dx553248635975856894)[Camogantí](https://expedia.ca/Camoganti.dx829297382853201920)[Paya](https://expedia.ca/Paya.dx829297452726095872)[Púcuro](https://expedia.ca/Pucuro.dx829297458059177984)[Boca de Cupe](https://expedia.ca/Boca-De-Cupe.dx829297466781212672)[Yape](https://expedia.ca/Yape.dx829297475935293440)[El Real de Santa María](https://expedia.ca/El-Real-De-Santa-Maria.dx829297481505312768)[Pinogana](https://expedia.ca/Pinogana.dx829297485225668608)[Yaviza](https://expedia.ca/Yaviza.dx829297489688424448)[Metetí](https://expedia.ca/Meteti.dx829297497563209728)[Manuel Ortega](https://expedia.ca/Manuel-Ortega.dx829297506843123712)[Cirilo Guainora](https://expedia.ca/Cirilo-Guainora.dx829297515193970688)[Lajas Blancas](https://expedia.ca/Lajas-Blancas.dx829297526369701888)[Río Iglesias](https://expedia.ca/Rio-Iglesias.dx829297548421255168)[Agua Fría](https://expedia.ca/Agua-Fria.dx829297553955622912)[Cañita](https://expedia.ca/Canita.dx829297618541613056)[Las Margaritas](https://expedia.ca/Las-Margaritas.dx829297622907908096)[Tortí](https://expedia.ca/Torti.dx829297631527182336)[Caimitillo](https://expedia.ca/Caimitillo.dx829297769735790592)[Puerto Obaldía](https://expedia.ca/Puerto-Obaldia.dx829297796248002560)[Tubualá](https://expedia.ca/Tubuala.dx829297812280709120)[Ailigandí](https://expedia.ca/Ailigandi.dx829297826484744192) - [Isla Mamey ](https://expedia.ca/Isla-Mamey-Colon.d553248623454093160.Vacation-Attraction) - [Cayos Holandeses ](https://expedia.ca/Cayos-Holandeses-Guna-Yala.d553248621579133545.Vacation-Attraction) - [Colon Free Zone ](https://expedia.ca/Colon-Free-Zone-Barrio-Sur.d6078503.Vacation-Attraction) - [Chagres National Park ](https://expedia.ca/Chagres-National-Park-Panama.d6252818.Vacation-Attraction) ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. 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