Title: Eastern Panama Vacation Rentals from CA $147: Short-Term Rentals for 2026 | Expedia.ca [Eastern Panama Travel Guide](https://expedia.ca/Eastern-Panama.dx6246114)[Hotels in Eastern Panama](https://expedia.ca/Eastern-Panama-Hotels.d6246114.Travel-Guide-Hotels)[Flights to Eastern Panama](https://expedia.ca/Cheap-Flights-To-Eastern-Panama.d6246114.Travel-Guide-Flights)[Eastern Panama Car Rentals](https://expedia.ca/Car-Rentals-In-Eastern-Panama.d6246114.Car-Rental-Guide)[Eastern Panama Vacation Packages](https://expedia.ca/Eastern-Panama.d6246114.Destination-Travel-Guides) ![50 Shades of blue. Sailing through the San Blas Islands in Panama lets you experience a pure paradise and crystal clear water. You can buy fresh fish and other seefood drirectly from local fishermen. If you want you can also play Robinson Crusoe on islands with literally only one palm tree. #BVSBlue](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Nico Barner ![](https://images.trvl-media.com/place/6246376/42fe0cae-c805-47d5-a705-ee119c68d58c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-02-20&endDate=2026-02-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 3 - Apr 5](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-04-03&endDate=2026-04-05&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 1 - May 3](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=6246114&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Eastern Panama vacation rentals ![Aerial view](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/18bb90d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/65220156.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin, Ocean View](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/c0f0b05f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Over the Water Cabin on San Blas Island [](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) Narganá 7.0/10 Good (6 reviews) "Very nice. And I liked the food " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher [](https://www.expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ![Boating](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/fad9e47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/edcd0ecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/1c15e003.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin | Beach/ocean view](https://images.trvl-media.com/lodging/47000000/46960000/46955400/46955399/8b5aa11c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Private Oceanfront Cabin [](https://www.expedia.ca/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information) Narganá CA $354 CA $526 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Blas-Private-Oceanfront-Cabin.h46955399.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/99016f78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/f4818252.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/749a0f9c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/47000000/46960000/46955900/46955891/ba1656e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Private Beach Cabin [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information) Narganá [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Beach-Cabin.h46955891.Hotel-Information) ![Dock](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/533ab64d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/c2647d0c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/4091b21d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin | Beach/ocean view](https://images.trvl-media.com/lodging/47000000/46950000/46949400/46949355/4fa56cde.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Over-Water Cabins on San Blas Island [](https://www.expedia.ca/San-Blas-Islands-Hotels-Prvt-Beach-Cabins-In-San-Blas-Islands.h46949355.Hotel-Information) Narganá CA $286 CA $451 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Prvt-Beach-Cabins-In-San-Blas-Islands.h46949355.Hotel-Information) ![Basic Cabin, Ocean View | Beach](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/db3e2027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Ocean View | Property grounds](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/aacdaacb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Ocean View | Beach](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/w3056h3853x0y0-a025e370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Ocean View | Exterior](https://images.trvl-media.com/lodging/125000000/124420000/124417300/124417283/a8dab923.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sanblastourgy [](https://www.expedia.ca/Nargana-Hotels-Sanblastourgy.h124417283.Hotel-Information) Nargana CA $343 CA $377 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Nargana-Hotels-Sanblastourgy.h124417283.Hotel-Information) ![Outdoor pool, a natural pool](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/6e039867.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room | Private kitchen](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/9c1f138a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sundeck](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/d1233249.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room](https://images.trvl-media.com/lodging/41000000/40920000/40917000/40916962/7d6772aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Over-the-Water Cabin in San Blas including Meals [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Prvt-Sailboat-Island-Hopping.h40916962.Hotel-Information) Mirladub [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Prvt-Sailboat-Island-Hopping.h40916962.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/803cd264.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/9304c3cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/1b7d8cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/72000000/71150000/71141100/71141036/c41bafb2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Catamaran experience in paradise [](https://www.expedia.ca/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information) Guna Yala Comarca CA $808 CA $1,658 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Catamaran-Experience-In-Paradise.h71141036.Hotel-Information) ![Beach nearby, beach towels](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/a2a99590.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/6f230b81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/da467749.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/114000000/113060000/113058600/113058539/07d1058d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Exclusive sailboat for 2 people all inclusive in San Blas islands [](https://www.expedia.ca/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information) Guna Yala 10/10 Exceptional (1 review) "Anita e Federico sono state il valore aggiunto in queste isole meravigliose. La loro disponibilita, le loro attenzioni, i sorridenti contatti di Anita con la popolazione dei Guna e la cucina superlativa di Federico hanno reso speciale la nostra vacanza che ha soddisfatto appieno le nostre aspettative. Discreta e deliziosa la presenza della gattina (la principessa di bordo) Shanu. Grazie di tutto!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Grazia B. CA $725 CA $829 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/Ailigandi-Hotels-Vrbo-Property.h113058539.Hotel-Information) ![Basic Cabin, Multiple Beds, Balcony, Sea View | Beach/ocean view](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/5e4a77e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Basic Cabin, Multiple Beds, Balcony, Sea View | Bathroom](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/0c7c55ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/d4916902.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms](https://images.trvl-media.com/lodging/108000000/107990000/107987100/107987054/e1ca9c21.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Tour Aridub [](https://www.expedia.ca/San-Blas-Tour-Aridub.h107987054.Hotel-Information) Narganá CA $117 CA $340 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Blas-Tour-Aridub.h107987054.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/0b910251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/3d134b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/w1296h891x0y0-1b08f53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, stovetop, coffee/tea maker, toaster](https://images.trvl-media.com/lodging/121000000/120040000/120034500/120034445/bb4bcbb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama [](https://www.expedia.ca/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information) Guna Yala Comarca CA $1,080 CA $1,273 total includes taxes & fees Feb 16 - Feb 17 [](https://www.expedia.ca/Fabulous-4-Bedroom-Catamaran-In-San-Blas-Panama.h120034445.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/1649bd69.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/7ad3ced9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/073e10ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103640000/103636800/103636720/4fd01df8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cabaña La Punta op het Strand!! [](https://www.expedia.ca/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information) Colón Province CA $178 CA $232 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Cativa-Hotels-Cabana-La-Punta-Op-Het-Strand.h103636720.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/95ace113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/14bad027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/30f0b989.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/121000000/120070000/120061100/120061071/551ebe2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deluxe Beachfront 4-bedroom house in Colón Province [](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) Colón Province CA $464 CA $528 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Isla-Grande-Hotels-Deluxe-Beachfront-4-Bedroom-House-In-Colon-Province.h120061071.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/fa337c68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/d70c8750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/b2886ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Beach](https://images.trvl-media.com/lodging/34000000/33020000/33018800/33018721/e6b8f41d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private cabin in San Blas [](https://www.expedia.ca/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information) Panama , Betania CA $362 CA $410 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Blas-Islands-Hotels-Private-Cabin-In-San-Blas.h33018721.Hotel-Information) ![Marina](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/de84a70a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/fef7062f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/9f704818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/109000000/108570000/108562100/108562093/a6aae70d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Despierta sobre el mar [](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) Garrote 6.0/10 (1 review) CA $103 CA $147 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Puerto-Lindo-Hotels-Despierta-Sobre-El-Mar.h108562093.Hotel-Information) ![Boating](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/b3b793d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/d29880fa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/f7f8513a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Panoramic Cabin | Terrace/patio](https://images.trvl-media.com/lodging/47000000/46950000/46949700/46949679/268dce26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### San Blas Private Over-the-Water Cabin [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Over-The-Water-Cabin.h46949679.Hotel-Information) Narganá 8.0/10 Very good (2 reviews) "I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay... ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Andrew CA $343 CA $514 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/San-Blas-Islands-Hotels-San-Blas-Private-Over-The-Water-Cabin.h46949679.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/1f45d7b8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/d2331d06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/743536b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/46000000/45030000/45022900/45022806/810fb7dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Jacuzy, pool and lake at the same house. [](https://www.expedia.ca/Bouvet-Island-Hotels-Vrbo-Property.h45022806.Hotel-Information) Colon 6.0/10 (2 reviews) "Great. Please take care of the cat" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KENNETH E. CA $47 CA $95 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Bouvet-Island-Hotels-Vrbo-Property.h45022806.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/3c7390e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/e818f21b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/1918a65d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/108000000/107130000/107121900/107121885/b0a6724c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hacienda La Perezosa in Cerro Azul [](https://www.expedia.ca/24-De-Diciembre-Hotels-Hacienda-La-Perezosa-In-Cerro-Azul.h107121885.Hotel-Information) Panamá CA $1,094 CA $1,361 total includes taxes & fees Feb 11 - Feb 12 [](https://www.expedia.ca/24-De-Diciembre-Hotels-Hacienda-La-Perezosa-In-Cerro-Azul.h107121885.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/eefeb662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/46b29819.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/bc739ca2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, WiFi, bed sheets](https://images.trvl-media.com/lodging/119000000/118960000/118951200/118951165/f4e54b7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming cottage with 2 separate beds and a beautiful view of the river [](https://www.expedia.ca/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information) Santa Rosa 10/10 Exceptional (1 review) "Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank." ![Germany](https://a.travel-assets.com/egds/marks/flags/de.svg) Birgit U. CA $172 CA $200 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Santa-Rosa-Hotels-Charming-Cottage-With-2-Separate-Beds-And-A-Beautiful-View-Of-The-River.h118951165.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/113000000/112340000/112331300/112331273/8532e872.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/113000000/112340000/112331300/112331273/f646cd87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/113000000/112340000/112331300/112331273/ed7ad575.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/113000000/112340000/112331300/112331273/8a79cd26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming 3-bedroom villa with AC and WiFi in soothing Río Hato [](https://www.expedia.ca/Portobelo-Hotels-Charming-3-Bedroom-Villa-With-AC-And-WiFi-In-Soothing-Rio-Hato.h112331273.Hotel-Information) Río Hato CA $277 CA $558 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Portobelo-Hotels-Charming-3-Bedroom-Villa-With-AC-And-WiFi-In-Soothing-Rio-Hato.h112331273.Hotel-Information) ![Beach](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/9bf6774d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/23785068.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/bde6b74f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/116000000/115840000/115832800/115832785/ea8360be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Bala Bliss Charming 2-bedroom apartment with WiFi, AC in Maria Chiquita [](https://www.expedia.ca/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information) Maria Chiquita 6.8/10 (3 reviews) "Well-appointed apartment, view of the ocean, big pool, fast Internet, attentive security. We had a great time here, thanks!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Will CA $137 CA $212 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Maria-Chiquita-Hotels-Bala-Bliss-Charming-2-Bedroom-Apartment-With-WiFi.h115832785.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-22&endDate=2026-02-23®ionId=6246114&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Apartments [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=APARTMENT) Cabins [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=CABIN) Villas [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=VILLA) Condos [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=CONDO) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=COTTAGE) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=VACATION_HOME) Houseboats [](https://www.expedia.ca/Hotel-Search?destination=Eastern+Panama%2C+Panama®ionId=6246114&latLong=9.01276%2C-78.243715&adults=2&startDate=2026-05-09&d1=2026-05-09&endDate=2026-05-12&d2=2026-05-12&lodging=HOUSE_BOAT) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FEastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FEastern-Panama-Vacation-Rentals.d6246114.Travel-Guide-VacationRentals) ## Top Eastern Panama Hotel Reviews ![Ciel y Miel ](https://images.trvl-media.com/lodging/97000000/96740000/96735000/96734959/7979d8c3_y.jpg) ### Ciel y Miel 10/10 Excellent "The views from this mountain-top boutique hotel are extraordinary." [](https://expedia.ca/Cacique-Hotels-Ciel-Y-Miel.h96734959.Hotel-Information) ![Ordovician Beach Resort](https://images.trvl-media.com/lodging/104000000/103770000/103761600/103761591/4a052041_y.jpg) ### Ordovician Beach Resort 10/10 Excellent "The best service in Panama!!! We truly felt cared for in every detail — the team is attentive, warm, and genuinely professional. The food was outstanding: the chef is exceptional! Every dish reflected passion, quality, and pride. This hotel is located on a beautiful Caribbean island, surrounded by untouched nature, turquoise waters, and a truly magical atmosphere. What made it even more special was the silence and privacy — only the sound of the waves and the singing of birds!) A wonderful resort and a place we’ll definitely return to!" [](https://expedia.ca/Ordovician-Beach-Resort.h103761591.Hotel-Information) ![Hotel Cocotal](https://images.trvl-media.com/lodging/117000000/116790000/116790000/116789972/c828cfe9_y.jpg) ### Hotel Cocotal 10/10 Excellent "Excelente hospedaje lo mejor la amabilidad de José Ángel y los demás muchachos... Con decirles que hasta te llevan a la habitación si te has tomado algunos tragos.. recomendada al 100" [](https://expedia.ca/La-Guaira-Hotels-Hotel-Cocotal.h116789972.Hotel-Information) ![Ranchos de Chalia](https://images.trvl-media.com/lodging/106000000/105450000/105444000/105443903/5fee50e0_y.jpg) ### Ranchos de Chalia 10/10 Excellent "Beautiful tranquility in nature, amazing staff" [](https://expedia.ca/Puerto-Lindo-Hotels-Ranchos-De-Chalia.h105443903.Hotel-Information) ![HOTEL ISLA GRANDE ](https://images.trvl-media.com/lodging/120000000/119950000/119947200/119947185/9e6abf31_y.jpg) ### HOTEL ISLA GRANDE 6/10 Okay "Although I gave this hotel a medium rating I enjoyed myself. This is a rough almost close to camping hotel. I must have not seen the message about bringing soap wash clothes, hand towel, tissue actually everything. The water does not get cold and there was a party set up just outside the window lasting until 5 am. There are no amenities however the caribbean ocean is just outside the door. " [](https://expedia.ca/Isla-Grande-Hotels-HOTEL-ISLA-GRANDE.h119947185.Hotel-Information) ![Private Over the Water Cabin on San Blas Island](https://images.trvl-media.com/lodging/38000000/37720000/37715900/37715808/f17df0ed_y.jpg) ### Private Over the Water Cabin on San Blas Island 10/10 Excellent "Very nice. And I liked the food " [](https://expedia.ca/San-Blas-Islands-Hotels-Cabins-Over-The-Water-Wailidup-Island.h37715808.Hotel-Information) ## Find out more about Eastern Panama You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded. As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Eastern Panama. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do. ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca - All accommodation types in Eastern Panama ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals) - 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