A calm sea with a small boat and a row of palm trees on the shore.

Eastern Panama Vacation Rentals

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Our top choices for Eastern Panama vacation rentals

1. san blas luxury tour

san blas luxury tour
2.0 star property
Nusatupo
The price is CA $153
CA $172 total
includes taxes & fees
Oct 23 - Oct 24
san blas luxury tour

2. glampling sanblas luxury

glampling sanblas luxury
1.0 star property
Nargana
The price is CA $484
CA $532 total
includes taxes & fees
Oct 23 - Oct 24
glampling sanblas luxury

3. San Blas Tour Aridub

San Blas Tour Aridub
2.0 star property
Narganá
The price is CA $109
CA $338 total
includes taxes & fees
Nov 1 - Nov 2
San Blas Tour Aridub

4. Beachfront Cabin on the San Blas Islands: Aroma

Beachfront Cabin on the San Blas Islands: Aroma
Guna Yala
The price is CA $95
CA $231 total
includes taxes & fees
Oct 19 - Oct 20
Beachfront Cabin on the San Blas Islands: Aroma

5. San Blas Private Beach Cabin

San Blas Private Beach Cabin
2.5 star property
Narganá
The price is CA $330
CA $363 total
includes taxes & fees
Nov 7 - Nov 8
San Blas Private Beach Cabin

6. San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin
2.5 star property
Narganá
The price is CA $366
CA $544 total
includes taxes & fees
Oct 19 - Oct 20
San Blas Private Oceanfront Cabin

7. Pelicano Island

Pelicano Island
2.0 star property
Moraquedub
The price is CA $458
CA $504 total
includes taxes & fees
Oct 20 - Oct 21
Pelicano Island

8. Sanblastourgy

Sanblastourgy
2.0 star property
Nargana
The price is CA $287
CA $316 total
includes taxes & fees
Oct 19 - Oct 20
Sanblastourgy

9. Private Over-Water Cabins on San Blas Island

Private Over-Water Cabins on San Blas Island
2.5 star property
Narganá
The price is CA $296
CA $467 total
includes taxes & fees
Oct 19 - Oct 20
Private Over-Water Cabins on San Blas Island

10. Private Over-the-Water Cabin in San Blas including Meals

Private Over-the-Water Cabin in San Blas including Meals
2.5 star property
Mirladub
The price is CA $624
CA $757 total
includes taxes & fees
Oct 20 - Oct 21
Private Over-the-Water Cabin in San Blas including Meals

11. All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
Guna Yala Comarca
The price is CA $1,070
CA $1,271 total
includes taxes & fees
Oct 19 - Oct 20
All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

12. San Blas Private Over-the-Water Cabin

San Blas Private Over-the-Water Cabin
2.5 star property
Narganá
8.0 out of 10, Very good, (2 reviews)
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...
United States
Andrew
The price is CA $335
CA $510 total
includes taxes & fees
Oct 19 - Oct 20
San Blas Private Over-the-Water Cabin

13. Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand
Palenque
9.0 out of 10, Wonderful, (4 reviews)
"the view is beautiful! We were taken care of well."
United States
Mirelys
The price is CA $342
CA $448 total
includes taxes & fees
Oct 19 - Oct 20
Caribbean getaway: beach cottage just on the sand

14. Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking
Puerto Lindo
The price is CA $318
CA $363 total
includes taxes & fees
Oct 19 - Oct 20
Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

15. Elegance and comfort in old town panama

Elegance and comfort in old town panama
Panamá
2.0 out of 10, (1 review)
"The address that’s depicted is not accurate to the map that’s shown and I tried multiple times to communicate with the host and no response"
United States
PAMELA
The price is CA $71
CA $127 total
includes taxes & fees
Oct 19 - Oct 20
Elegance and comfort in old town panama

16. Tiny Cabin

Tiny Cabin
3.0 star property
Panamá
10.0 out of 10, Exceptional, (1 review)
The price is CA $189
CA $208 total
includes taxes & fees
Oct 19 - Oct 20
Tiny Cabin

17. Cozy Cabin in the Misty Mountain

Cozy Cabin in the Misty Mountain
Panamá
The price is CA $113
CA $163 total
includes taxes & fees
Oct 19 - Oct 20
Cozy Cabin in the Misty Mountain

18. Cozy and Safe Environment Close to the Airport.

Cozy and Safe Environment Close to the Airport.
Panamá
The price is CA $88
CA $116 total
includes taxes & fees
Oct 20 - Oct 21
Cozy and Safe Environment Close to the Airport.

19. Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway
Panamá
The price is CA $170
CA $198 total
includes taxes & fees
Oct 19 - Oct 20
Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

20. Your country home, Menus de la Montaña, awaits you

Your country home, Menus de la Montaña, awaits you
Panama
The price is CA $140
CA $332 total
includes taxes & fees
Oct 19 - Oct 20
Your country home, Menus de la Montaña, awaits you
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Eastern Panama Hotel Reviews

Find out more about Eastern Panama

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Eastern Panama. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.