Book The Best Hotels in South Carolina Midlands, SC for 2026 from CA $94 - Fully Refundable Options

A monument with a statue on top, in front of a large building with columns.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in South Carolina Midlands

Pet friendly

Apartment

Villa

Spa

Pool

Apart hotel

Hot tub

Condo

Family friendly

Cottage

Farm

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for South Carolina Midlands hotels

In-room safe, desk, laptop workspace, blackout drapes

1. Holiday Inn Express Columbia NE - Fort Jackson by IHG

Columbia

Christine

CA $158

CA $177 total

includes taxes & fees

Sep 14 - Sep 15

Desk, laptop workspace, blackout drapes, iron/ironing board

2. Wyndham Garden Columbia/Ft. Jackson

Columbia

Spencer

CA $109

CA $122 total

includes taxes & fees

Sep 20 - Sep 21

3. La Quinta Inn by Wyndham Columbia NE/Fort Jackson

Columbia

Richard

CA $116

CA $130 total

includes taxes & fees

Sep 20 - Sep 21

4. Hampton Inn & Suites Columbia Killian Road

Columbia

Valerie

CA $171

CA $192 total

includes taxes & fees

Sep 27 - Sep 28

5. Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG

Columbia

Raymond

CA $138

CA $155 total

includes taxes & fees

Sep 27 - Sep 28

Hypo-allergenic bedding available, in-room safe, desk, laptop workspace

6. Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

Carlos

CA $126

CA $142 total

includes taxes & fees

Sep 27 - Sep 28

7. Delta Hotels by Marriott Columbia Northeast

Columbia

Donna

CA $135

CA $152 total

includes taxes & fees

Sep 22 - Sep 23

Hypo-allergenic bedding available, pillowtop beds, desk

8. Tru By Hilton Columbia Greystone

Columbia

Kiera

CA $135

CA $154 total

includes taxes & fees

Sep 27 - Sep 28

9. Tru By Hilton Columbia Downtown

Downtown Columbia

Laurel

CA $135

CA $151 total

includes taxes & fees

Sep 27 - Sep 28

10. Hampton Inn & Suites Columbia/Southeast-Ft. Jackson

Columbia

Devine

CA $140

CA $157 total

includes taxes & fees

Sep 27 - Sep 28

Premium bedding, pillowtop beds, desk, blackout drapes

11. Comfort Inn Blythewood - North Columbia

Blythewood

Amy

CA $118

CA $133 total

includes taxes & fees

Oct 4 - Oct 5

32-inch LCD TV with digital channels, TV

12. TownePlace Suites by Marriott Columbia Southeast/Ft Jackson

Columbia

Elizabeth

CA $132

CA $148 total

includes taxes & fees

Sep 27 - Sep 28

Premium bedding, in-room safe, desk, iron/ironing board

13. Holiday Inn Express & Suites Columbia-Fort Jackson by IHG

Columbia

Rose Marie

CA $157

CA $176 total

includes taxes & fees

Sep 27 - Sep 28

Studio Suite, 1 Queen Bed, Accessible (Hearing) | Private kitchen

14. LivSmart Studios by Hilton Columbia Greystone

Columbia

Robertson

CA $157

CA $179 total

includes taxes & fees

Sep 20 - Sep 21

Premium bedding, down comforters, desk, laptop workspace

15. Country Inn & Suites by Radisson, Columbia Airport, SC

Cayce

Liaisha

CA $135

CA $150 total

includes taxes & fees

Oct 4 - Oct 5

16. Aloft by Marriott Columbia Downtown

Downtown Columbia

Robert

CA $169

CA $190 total

includes taxes & fees

Sep 13 - Sep 14

2 Queen Beds, Refreshed Deluxe Room, Non-Smoking

17. La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Columbia

Lina

CA $141

CA $158 total

includes taxes & fees

Sep 13 - Sep 14

18. Hotel Trundle

Downtown Columbia

Anthony

CA $198

CA $222 total

includes taxes & fees

Sep 20 - Sep 21

19. Hampton Inn & Suites Lexington Columbia

Lexington

Alan

CA $164

CA $182 total

includes taxes & fees

Sep 20 - Sep 21

20. Sheraton Columbia Downtown Hotel

Downtown Columbia

Ericka

CA $157

CA $176 total

includes taxes & fees

Sep 27 - Sep 28

View all properties

Vacation Rentals in South Carolina Midlands

Apartment

Easy Access to I-77 & I-20: Columbia Duplex!

Columbia

"Good rental. The only downside was that there was a strong cigar odor the first two days. I also found a few uncleaned hairs lying around on the counter and bed. Other than that, it’s a good home for a quick trip. Especially if you’re visiting for Fort Jackson purposes."

Aparthotel

StudioRes by Marriott Columbia Harbison

Columbia

"Probably one of the best hotels I’ve been to in a while, especially considering the price!"

Aparthotel

1 bedroom, iron/ironing board, WiFi (free), bed sheets

Full-size fridge, microwave, oven, stovetop

stayAPT Suites Columbia-Irmo Harbison

Irmo

"Staff on property were very friendly and Professional."

Aparthotel

55-inch flat-screen TV with cable channels, TV

Coffee/tea maker, full-size fridge, microwave, oven

The Hangar Lofts Hotel

Rosewood

"Clean convenient and great hospitality. "

Cabin

Long Cove Resort near Charlotte Airport

Steele Creek

"It is a perfect location and sweet place."

Vacation Home

Signature Townhome, 3 Bedrooms, Balcony, River View | Water view

Signature Townhome, 3 Bedrooms, Balcony, River View | In-room dining

Signature Townhome, 3 Bedrooms, Balcony, River View | Living area

Beautiful 3BR Townhouse

East Augusta

"The water view and close proximity to restaurants and shops The place was as pictured and some. Very quiet and relaxing place. Will definitely be booking again"

Cottage

Columbia Vacation Rental < 2 Mi to University

Downtown Columbia

"House was very welcoming, with a cottage vibe, the older home renovations mixed with the floor and trim work over the doors was beautiful and unique. Very updated home nicely done. "

Aparthotel

stayAPT Suites Rock Hill

Rock Hill

"The room was nice… but when you say you have a full kitchen I would at least expect a frying pan of a cookie sheet. I left salt and pepper for the next guest bc there was NOTHING… not even paper towels. If you want anything go buy it bc they do not offer anything…. This is BARE mimium i am surprise that Expedia uses them. Its a great concept but not well executed"

Cottage

Family Home w/ Fire Pit, 2 Mi to Lake Access

Lexington

"Thank you so much for having spices in the drawer"

Cottage

3 Mi to Marina: Quiet Getaway w/ Deck in Lexington

Lexington

"Very cozy home lots of room and kept clean!"

Cottage

Bright Hopkins Home w/ Game Room & Fire Pit!

Hopkins

Cottage

4 Mi to Marina & Boat Ramp: Lake Murray Getaway!

Chapin

"Exceptionally clean! "

Apartment

Backyard Oasis w/ Pool: Sunny Sumter Studio!

Sumter

"The studio was very clean, decorated nicely, and cozy. The location is quiet and easy to find. Communication was punctual. I really enjoyed my stay"

Cottage

Lake Access & Boat Slip: Greenwood Cottage!

Greenwood

"Outstanding little cottage for my mom and daughter weekend! Super clean and comfortable. "

See all vacation rentals

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular South Carolina Midlands attractions

A cityscape at dusk with illuminated buildings, a prominent dome structure, and a well-lit street.

University of South Carolina

9.0/10 (2,467 reviews)

Walk around the campus of University of South Carolina, a top university in Columbia. Experience the area's acclaimed theater scene or attend a sporting event.

See properties

A roller coaster with multiple tracks and loops.

Carowinds Theme Park

8.8/10 (962 reviews)

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

See properties

A pond with flamingos standing in the water.

Riverbanks Zoo and Garden

8.8/10 (1,195 reviews)

Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.

See properties

A swampy forest with tall trees and a calm water body reflecting the sky.

Congaree National Park

8.4/10 (365 reviews)

While protecting southern hardwood forest for the enjoyment of future generations, this park also offers hiking, canoeing and interesting ranger-led activities.

See properties

Williams Brice Stadium

8.8/10 (938 reviews)

Catch an event at Williams Brice Stadium during your trip to Columbia. You can attend a sporting event while in the area.

See properties

Colonial Life Arena

8.8/10 (1,029 reviews)

Catch an event at Colonial Life Arena during your trip to Columbia. Experience the area's acclaimed theater scene or attend a sporting event.

See properties

Darlington Raceway

8.2/10 (151 reviews)

Catch an event at Darlington Raceway during your trip to Darlington. While in this trendy area, you can savor the top-notch restaurants.

See properties

Learn more about South Carolina Midlands

With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

See all hotels in South Carolina Midlands

Top South Carolina Midlands Hotel Reviews

Wyndham Garden Columbia/Ft. Jackson

10/10 Excellent

"Very clean and extremely helpful staff"

Quality Inn & Suites Florence Civic Center

8/10 Good

"Good stay, friendly staff. Breakfast buffet was lacking for price of room. Nice outdoor pool"

Park Inn by Radisson Florence, SC

8/10 Good

"Clean, comfortable mattress, silky sheets. indoor pool did not have a heater water temperature was too cold. Continental breakfast just Ok…could be better. Location good, right off I95."

Tru By Hilton Columbia Greystone

8/10 Good

"Staff was great. However the exit sign was hanging from the roof by a wire.. not really safe. The room we were first in was filthy. However they moved me when I complained. They were very nice my girls were happy in the end."

Howard Johnson by Wyndham Florence

8/10 Good

"Nice clean room, very comfortable bed! Breakfast was poor!"

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

10/10 Excellent

"Good overnight stay in our way to Florida. We will be back in our way home. I’d recommend. The breakfast was good. David at the front desk was friendly and very helpful!"

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

10/10 Excellent

"Staff at check-in was professional, and friendly. Lobby area was clean and well maintained. Room was very clean and pool area was great."

Sleep Inn Columbia

10/10 Excellent

"Upon arrival Beth W the front desk night staff was very helpful, efficient, uplifting. She found we had two accounts and over night printed them out and put under our door so we could get them figured out. The continental breakfast in the morning, was less than desired, and I waited for the front desk to tell them we were checking out for 5 minutes and nobody showed up. Those were the only drawbacks but with all the traveling we have done, this was a good hotel."

Quality Inn Columbia Airport

10/10 Excellent

"Room was clean. Location was convenient. Staff was very nice. Breakfast included. Many food options around the hotel and a Walmart. Convenient to the airport. Room recently renovated."

More cheap stays in South Carolina Midlands

Quality Inn Columbia Airport

2516 Augusta Rd West Columbia SC

CA $87

CA $94 total

Oct 7 - Oct 8

includes taxes & fees

6.8/10 (1,003 reviews)