Book The Best Hotels in South Carolina Midlands, SC for 2026 from CA $96 - Fully Refundable Options

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Our top choices for South Carolina Midlands hotels

A spacious lobby with a high ceiling, a staircase, and a seating area with a patterned sofa and armchairs.

A Holiday Inn Express building with a modern design, large windows, and a parking lot in front.

A coffee station with two espresso machines and a variety of coffee pods and cups.

A hotel room with two beds, a desk, a TV, and a wardrobe.

1. Holiday Inn Express Columbia NE - Fort Jackson by IHG

Columbia

April

CA $156

CA $174 total

includes taxes & fees

Oct 14 - Oct 15

A Hampton Inn & Suites with a rooftop pool, outdoor seating, and a modern architectural design.

A modern hotel corridor with wooden flooring, dark brick walls, and a large abstract art piece.

A hotel room with a bed, desk, television, and a sliding door leading to a bathroom.

A conference room with a long table, chairs, and a patterned carpet.

2. Hampton Inn & Suites Columbia Killian Road

Columbia

William

CA $184

CA $207 total

includes taxes & fees

Oct 11 - Oct 12

A hotel entrance with a covered walkway, stone pillars, and a glass door entrance.

A snack and beverage vending machine with various snacks and drinks.

A modern living room with a gray sofa, two chairs, a coffee table, and a large window offering a view of greenery.

A modern dining area with round tables and chairs, a bar area, and a seating section with benches.

3. Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG

Columbia

Jose Santos

CA $148

CA $166 total

includes taxes & fees

Oct 18 - Oct 19

A panoramic mosaic mural of a cityscape with buildings and greenery.

A neon sign with the text "You're gorgeous Columbia" against a dark wall with vertical lines and horizontal gold bars.

A hotel lobby with a reception desk, a large cityscape mural, and a door leading to a parking area.

A hotel room with two beds, a nightstand with a phone and lamp, and two large landscape paintings on the wall.

4. La Quinta Inn by Wyndham Columbia NE/Fort Jackson

Columbia

Olujimi

CA $119

CA $134 total

includes taxes & fees

Oct 11 - Oct 12

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

A modern reception area with a large digital display, a counter, and vending machines.

A modern hotel lobby with a curved sofa, dining area, and a kitchen in the background.

A modern kitchen with dark wood cabinets, a white countertop, and various kitchen appliances.

5. Springhill Suites by Marriott Columbia near Fort Jackson

Columbia

Carlos

CA $142

CA $159 total

includes taxes & fees

Oct 25 - Oct 26

A spacious lobby with multiple seating areas, a reception desk, and a large window providing natural light.

A reception area with a Wyndham Garden sign, a reception desk, and a check-in counter.

A hotel room with a bed, a gray sofa with red cushions, a red armchair, a floor lamp, and a framed abstract painting on the wall.

A courtyard with artificial grass, outdoor seating, and palm trees.

6. Wyndham Garden Columbia/Ft. Jackson

Columbia

Carrington

CA $111

CA $124 total

includes taxes & fees

Oct 11 - Oct 12

A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.

A modern lounge area with a blue sofa, hanging chairs, and a table with chairs.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern cafe with a central display of snacks and beverages, a seating area with sofas, and a ceiling with unique lighting fixtures.

7. Tru By Hilton Columbia Greystone

Columbia

Kim

CA $142

CA $161 total

includes taxes & fees

Oct 18 - Oct 19

A modern interior with a reception desk, a bench, and a wall with a bulletin board.

A modern laundry room with a table, chairs, and washing machines.

A hotel room with two beds, a desk, a chair, and a bathroom visible through an open door.

A gym with treadmills, weight benches, dumbbells, and a large motivational mural.

8. LivSmart Studios by Hilton Columbia Greystone

Columbia

Robertson

CA $161

CA $184 total

includes taxes & fees

Oct 11 - Oct 12

A modern bar area with a long counter, multiple bar stools, and a decorative wall with geometric patterns.

An outdoor patio with a bar area, seating, and a grill station.

A modern lounge area with a sectional sofa, two armchairs, a coffee table, and a wall-mounted TV.

A multi-story hotel with a modern design, featuring a mix of brick and glass facades, and a prominent entrance with a covered walkway.

9. Tru By Hilton Columbia Downtown

Downtown Columbia

Laurel

CA $167

CA $187 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor seating area with wicker chairs and a glass table, a fire feature, and a stone wall.

A Hampton Inn & Suites with a modern design, featuring a stone facade and a blue accent wall.

An indoor swimming pool with clear water, surrounded by tiled walls and windows.

A modern hotel lobby with blue upholstered chairs, round tables, a central bar area, and a wooden accent wall.

10. Hampton Inn & Suites Columbia/Southeast-Ft. Jackson

Columbia

Devine

CA $147

CA $165 total

includes taxes & fees

Oct 25 - Oct 26

A modern hotel room with a blue sofa, a wooden coffee table, a flat-screen TV, and a framed picture on the wall.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A lobby with a high ceiling, a reception area, a dining area, and an elevator.

An outdoor patio area with a pool, lounge chairs, and a sign for Holiday Inn Express & Suites.

11. Holiday Inn Express Hotel & Suites Blythewood by IHG

Blythewood

Erma Kilynda

CA $185

CA $207 total

includes taxes & fees

Oct 18 - Oct 19

A modern kitchen with a long counter, a coffee machine, and a refrigerator.

A hotel room with two beds, a desk, a chair, and a TV.

A modern living room with a flat-screen TV mounted on a textured wall, two sofas with decorative pillows, a patterned rug, and two side tables with plants.

A reception area with a cityscape mural, two reception desks, and a modern design.

12. La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Columbia

Todd

CA $144

CA $162 total

includes taxes & fees

Oct 25 - Oct 26

A modern bar area with a central island, bar stools, and a television.

A modern hotel room with a sectional sofa, a small table, and a TV mounted on the wall.

A spacious lobby with a reception desk, seating area, and large windows allowing natural light.

A hotel room with two beds, a sofa, a desk, and a large window.

13. Cambria Hotel Columbia Downtown The Vista

Downtown Columbia

Jeanne

CA $185

CA $207 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel lobby with a large dining table, multiple seating areas, and a large screen wall.

A hotel room with a bed, desk, chair, air conditioning unit, and a window with a view of trees.

A snack and sundries section with wooden shelves stocked with various snacks and beverages, and a wall mural with a circular design.

A modern kitchen area with a long counter, various food items, and a chalkboard with food-related drawings.

14. Hampton Inn & Suites Lexington Columbia

Lexington

LISA

CA $170

CA $189 total

includes taxes & fees

Oct 1 - Oct 2

A spacious lobby with a central seating area, a shop, and large potted plants.

A modern hotel lobby with wicker furniture, large windows, and a central light fixture.

A Hilton Garden Inn with a well-lit entrance, a covered waiting area, and a visible parking lot.

A room with a fireplace, bookshelves, two chairs, and a coffee table.

15. Hilton Garden Inn Columbia/Harbison

Columbia

Ann Marie

CA $126

CA $141 total

includes taxes & fees

Oct 11 - Oct 12

A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.

Two people celebrating with confetti in a bar setting.

A hotel lobby with a modern chandelier, a reception desk, and a staircase with decorative railings.

A hotel room with exposed brick walls, a large bed, a desk with a telephone, and a television on the wall.

16. Hotel Trundle

Downtown Columbia

Wendy

CA $204

CA $228 total

includes taxes & fees

Oct 12 - Oct 13

A modern living room with a grey sofa, a wooden bookshelf, a large wall clock, a fireplace, and a staircase.

A multi-story hotel with a modern design, featuring a covered entrance and a parking lot.

A hotel room with a large bed, two bedside tables with lamps, a red chair, a desk, and a large window with curtains.

17. Country Inn & Suites by Radisson, Columbia Airport, SC

Cayce

Ruth Marie

CA $146

CA $162 total

includes taxes & fees

Oct 18 - Oct 19

An outdoor patio with a stone fire pit, a grill, and red umbrellas.

A pool area with blue chairs and red umbrellas, surrounded by stone walls and windows.

TownePlace Suites by Marriott with a modern design, multiple floors, and a prominent American flag.

18. TownePlace Suites by Marriott Columbia Southeast/Ft Jackson

Columbia

Rick

CA $136

CA $152 total

includes taxes & fees

Oct 25 - Oct 26

A hotel room with a bed, a desk with a computer, a nightstand, a lamp, and a window with curtains.

A conference room with long tables and chairs, a projector screen, a storage area, and a carpeted floor.

A hotel room with a desk, a black office chair, a brown sofa, a TV displaying a movie, and a wall with framed artwork.

A modern hotel room with a sofa, a small table, a desk with a lamp, and a chair.

19. Residence Inn Columbia West/Lexington

West Columbia

Jennifer

CA $185

CA $200 total

includes taxes & fees

Oct 15 - Oct 16

A modern bar area with a bar counter, seating, and a variety of bottles.

A pool table in a modern indoor setting with large windows, a patterned rug, and bar stools.

A modern lounge area with blue sofas, yellow and red cushions, a glass coffee table, and a large mural of a cityscape.

A modern lounge area with a blue sofa, round tables, and artwork on the walls.

20. Aloft by Marriott Columbia Downtown

Downtown Columbia

Robert

CA $173

CA $197 total

includes taxes & fees

Oct 11 - Oct 12

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Vacation Rentals in South Carolina Midlands

Aparthotel

A multi-story hotel with a modern design, featuring a prominent 'STUDIOS' sign on the facade.

A gym with a mirrored wall, a pull-up bar, and a weight machine.

A compact hotel room with a kitchenette, a bed, a desk, and a chair.

A modern living room with a sofa, two side tables, a grey armchair, a large potted plant, and a patterned rug.

StudioRes by Marriott Columbia Harbison

Columbia

"Probably one of the best hotels I’ve been to in a while, especially considering the price!"

Apartment

A kitchen with white cabinets, a stainless steel refrigerator, a red coffee maker, and a clock on the wall.

A modern kitchen with white cabinets, a wooden dining table set with blue napkins, and a ceiling fan.

A bedroom with a bed, curtains, a ceiling fan, a nightstand with a lamp, and wall art.

A concrete patio area with a metal sign, surrounded by bamboo and other vegetation.

Easy Access to I-77 & I-20: Columbia Duplex!

Columbia

"Good rental. The only downside was that there was a strong cigar odor the first two days. I also found a few uncleaned hairs lying around on the counter and bed. Other than that, it’s a good home for a quick trip. Especially if you’re visiting for Fort Jackson purposes."

Aparthotel

A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.

A modern courtyard with white furniture, a central seating area, and a small lawn.

stayAPT Suites Columbia-Irmo Harbison

Irmo

"Hands down the cleanest,best priced affordable place I've ever had the pleasure of staying.feels more like home than a hotel.id give them 10 stars if I could.no complains what so ever."

Cabin

A view of a beach with chairs and a table, overlooking a body of water and a distant bridge.

A house with a wooden deck and a view of a lake.

A beach with people swimming, sunbathing, and boats on the water.

Long Cove Resort near Charlotte Airport

Steele Creek

"Lake view"

Vacation Home

A wooden pier leading to a dock with boats, surrounded by trees and a calm lake.

A spacious living area with a dining table, sofas, and a ceiling fan.

A modern dining room with a large wooden table, six chairs, and a decorative wall piece.

A waterfront property with a dock, a small gazebo, and a row of houses.

Beautiful 3BR Townhouse

East Augusta

"The location is quiet and removed from all the hectic traffic. Despite the difference from the listing photos, we had a comfortable stay."

Cottage

A covered patio with wicker furniture, a cushioned bench, and a view of a backyard with a wooden fence and trees.

A spacious living room with a large sofa, a coffee table, and a dining area in the background.

A kitchen with white cabinets, a stainless steel stove, and a potted plant.

A dining room with a wooden table, white chairs, a bench, and a hanging light fixture.

Columbia Vacation Rental < 2 Mi to University

Downtown Columbia

"House was very welcoming, with a cottage vibe, the older home renovations mixed with the floor and trim work over the doors was beautiful and unique. Very updated home nicely done. "

Aparthotel

A modern building with a sign reading "stay apt SUITES" and a number "840" on the facade.

stayAPT Suites Rock Hill

Rock Hill

"The room was nice… but when you say you have a full kitchen I would at least expect a frying pan of a cookie sheet. I left salt and pepper for the next guest bc there was NOTHING… not even paper towels. If you want anything go buy it bc they do not offer anything…. This is BARE mimium i am surprise that Expedia uses them. Its a great concept but not well executed"

Cottage

A corner room with a white table and two wooden stools, a potted plant on the table, and three windows with sheer curtains.

A spacious living room with a large sectional sofa, a wooden coffee table, and a staircase with wooden railings.

A kitchen with wooden cabinets, a sink, and a window.

A wooden deck with a railing, surrounded by lush greenery.

3 Mi to Marina: Quiet Getaway w/ Deck in Lexington

Lexington

"Very cozy home lots of room and kept clean!"

Cottage

A porch with Adirondack chairs and a sign reading "Margie's Place".

A modern kitchen with light blue cabinets, a stainless steel refrigerator, and a dining area with wooden chairs.

A laundry room with a washing machine and dryer, a small step leading to a door, and a coat rack with jackets.

A bedroom with a large bed, two bedside lamps, a ceiling fan, a door, and a window with a view of greenery.

Family Home w/ Fire Pit, 2 Mi to Lake Access

Lexington

"Thank you so much for having spices in the drawer"

Cottage

A living room with a leather sofa, a glass coffee table, a television, a fireplace, and a painting of boats.

A bedroom with a wooden bed, a nightstand, a ceiling fan, and a window with curtains.

A kitchen with wooden cabinets, a white stove, a microwave, and a sink.

A living room with a sofa, a coffee table, a dining area with a table and chairs, and a painting on the wall.

Peaceful Camden Vacation Rental ~ 3 Mi to Town!

Camden

"I enjoyed the property, it’s in a lovely neighborhood and everything is set up to be private and really easy to access. Close to Camden so within a few minutes of most things. I would definitely stay there again!"

Apartment

A living room with a gray sofa, a coffee table, a patterned rug, a bed, and a brick wall.

A swimming pool with lounge chairs and umbrellas, surrounded by greenery.

A living room with a gray sectional sofa, a coffee table, and a clock on the wall.

A covered outdoor seating area with a wooden deck, blue Adirondack chairs, and a wicker sofa.

Backyard Oasis w/ Pool: Sunny Sumter Studio!

Sumter

"The studio was very clean, decorated nicely, and cozy. The location is quiet and easy to find. Communication was punctual. I really enjoyed my stay"

Cottage

A spacious cabin with a wooden interior, a dining area with a table set for four, and a cozy living room with a sofa and chairs.

A cozy cabin interior with a dining area, kitchen, and living room.

A lakeside deck with outdoor seating and a dock extending into the water.

A two-story house with a porch, a covered patio, and a lawn.

Private Boat Dock: Waterfront Lake Murray Haven

Newberry Shores

"Beautiful home! Would stay here again."

Cottage

A living room with a stone fireplace, a flat-screen TV, a ceiling fan, and a large window with blinds.

A covered porch with a white railing, a welcome sign, and a door with a window.

A kitchen with white cabinets, a stove, and a sink.

A living room with a grey sofa, a beige armchair, and a wooden coffee table. There is a lamp on a side table, and a framed picture on the wall.

Prosperity Vacation Rental ~ 1 Mi to Lake Murray!

Hollands Landing

"The property had a lot of land. It was a peaceful, beautiful scenery. They had games in the house, ax throwing, corn hole outside & bonfire. Seeing the neighbors horses walk by was amazing. "

Cottage

A spacious living area with a sofa, armchairs, and a coffee table. A kitchen is visible in the background.

A spacious dining area with a large table set for six, a kitchen in the background, and a view of the outdoors through a window.

A modern kitchen with white cabinets, a central island, a microwave, and a stove.

Lake Marion Canal Home: Dock, Yard, Porch

Summerton

"Kitchen was great, bedooms accomodating. Love the porch!"

Cottage

A covered patio with outdoor seating, a view of a parking lot and distant landscape.

A modern kitchen with white cabinets, stainless steel appliances, and a granite countertop.

A spacious living area with a dining table, a leather sofa, and a spiral staircase.

A single-story house with a covered porch, a small garden, and a sign indicating it is a rental property.

Stunning Lakefront Retreat w/ Dock Access!

Greenwood

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Stay near popular South Carolina Midlands attractions

A cityscape at dusk with illuminated buildings, a prominent dome structure, and a well-lit street.

University of South Carolina

9.0/10 (2,467 reviews)

Walk around the campus of University of South Carolina, a top university in Columbia. Experience the area's acclaimed theater scene or attend a sporting event.

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A roller coaster with multiple tracks and a clear blue sky.

Carowinds Theme Park

8.8/10 (962 reviews)

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

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A pond with flamingos standing in the water.

Riverbanks Zoo and Garden

8.8/10 (1,195 reviews)

Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.

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A swampy forest with tall trees and a calm water body reflecting the sky.

Congaree National Park

8.4/10 (365 reviews)

While protecting southern hardwood forest for the enjoyment of future generations, this park also offers hiking, canoeing and interesting ranger-led activities.

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Colonial Life Arena

8.8/10 (1,029 reviews)

Catch an event at Colonial Life Arena during your trip to Columbia. Experience the area's acclaimed theater scene or attend a sporting event.

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Williams Brice Stadium

8.8/10 (938 reviews)

Catch an event at Williams Brice Stadium during your trip to Columbia. You can attend a sporting event while in the area.

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Township Auditorium

8.2/10 (556 reviews)

Enjoy a show at Township Auditorium, a theater with a story to tell in Columbia. Experience the area's acclaimed theater scene or attend a sporting event.

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Learn more about South Carolina Midlands

With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

See all hotels in South Carolina Midlands

Top South Carolina Midlands Hotel Reviews

La Quinta Inn & Suites by Wyndham Rock Hill

10/10 Excellent

"Zero complaints. We use this hotel several times a year, coming and going as we travel through the area, and never had an issue. It’s comforting to know that we have a good place to stay."

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

10/10 Excellent

"I absolutely enjoyed my stay. My king bed room was spacious and clean. The breakfast was great and was always plentiful. The staff were absolutely amazing!!!! Tiffany, Cherry the kitchen staff were very kind. A will stay here again for sure! Thank you all!"

Comfort Inn & Suites Florence Center Area

10/10 Excellent

"This property was just off the highway and was super clean. We were not expecting much for a pet friendly hotel which was just off the highway. But it was a very pleasant stay… the staff at the front desk were so friendly and made a great first impression from booking in to belreakfast in the Am.. it was well stocked and kept very clean! Parking was well lit and room was very clean and had shampoo conditioner and body wash and lotion for use!"

Tru By Hilton Columbia Greystone

10/10 Excellent

"Great staff"

Sleep Inn Columbia

8/10 Good

"Room was well equipped but could use a better cleaning. Parking lot well lit. Front lobby kinda drab. Front desk girl was pleasant and helpful. Breakfast extremely minimal. Overall, worth what we paid for"

More cheap stays in South Carolina Midlands

Quality Inn Columbia Airport

2516 Augusta Rd West Columbia SC

CA $89

CA $96 total

Oct 28 - Oct 29

includes taxes & fees

Motel 6 Fort Mill, SC - Charlotte

3541 Foothills Way Fort Mill SC

CA $85

CA $97 total

Sep 30 - Oct 1

includes taxes & fees

6.4/10 (1,146 reviews)

Quality Inn Fort Jackson

8104 Two Notch Rd Columbia SC

CA $89

CA $100 total

Oct 18 - Oct 19

includes taxes & fees

Wyndham Garden Columbia/Ft. Jackson

1539 Horseshoe Dr Columbia SC

CA $111

CA $124 total

Oct 11 - Oct 12

includes taxes & fees

Sleep Inn Columbia

1901 Rockland Rd Columbia SC

CA $119

CA $129 total

Oct 19 - Oct 20

includes taxes & fees

8.2/10 Very good! (1,195 reviews)

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

CA $126

CA $141 total

Oct 4 - Oct 5

includes taxes & fees

Hotels in South Carolina Midlands with star rating

Explore a world of travel with Expedia

Book Hotels in South Carolina Midlands on Expedia.com

Find hotels in South Carolina Midlands, SC from CA $96

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in South Carolina Midlands

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for South Carolina Midlands hotels

1. Holiday Inn Express Columbia NE - Fort Jackson by IHG

2. Hampton Inn & Suites Columbia Killian Road

3. Holiday Inn & Suites Columbia NE - Ft Jackson Area by IHG

4. La Quinta Inn by Wyndham Columbia NE/Fort Jackson

5. Springhill Suites by Marriott Columbia near Fort Jackson

6. Wyndham Garden Columbia/Ft. Jackson

7. Tru By Hilton Columbia Greystone

8. LivSmart Studios by Hilton Columbia Greystone

9. Tru By Hilton Columbia Downtown

10. Hampton Inn & Suites Columbia/Southeast-Ft. Jackson

11. Holiday Inn Express Hotel & Suites Blythewood by IHG

12. La Quinta Inn by Wyndham Columbia SE / Fort Jackson

13. Cambria Hotel Columbia Downtown The Vista

14. Hampton Inn & Suites Lexington Columbia

15. Hilton Garden Inn Columbia/Harbison

16. Hotel Trundle

17. Country Inn & Suites by Radisson, Columbia Airport, SC

18. TownePlace Suites by Marriott Columbia Southeast/Ft Jackson

19. Residence Inn Columbia West/Lexington

20. Aloft by Marriott Columbia Downtown

Vacation Rentals in South Carolina Midlands

StudioRes by Marriott Columbia Harbison

Easy Access to I-77 & I-20: Columbia Duplex!

stayAPT Suites Columbia-Irmo Harbison

Long Cove Resort near Charlotte Airport

Beautiful 3BR Townhouse

Columbia Vacation Rental < 2 Mi to University

stayAPT Suites Rock Hill

3 Mi to Marina: Quiet Getaway w/ Deck in Lexington

Family Home w/ Fire Pit, 2 Mi to Lake Access

Peaceful Camden Vacation Rental ~ 3 Mi to Town!

Backyard Oasis w/ Pool: Sunny Sumter Studio!

Private Boat Dock: Waterfront Lake Murray Haven

Prosperity Vacation Rental ~ 1 Mi to Lake Murray!

Lake Marion Canal Home: Dock, Yard, Porch

Stunning Lakefront Retreat w/ Dock Access!

Stay near popular South Carolina Midlands attractions

University of South Carolina

Carowinds Theme Park

Riverbanks Zoo and Garden

Congaree National Park

Colonial Life Arena

Williams Brice Stadium

Township Auditorium

Learn more about South Carolina Midlands

Top South Carolina Midlands Hotel Reviews

La Quinta Inn & Suites by Wyndham Rock Hill

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

Comfort Inn & Suites Florence Center Area

Tru By Hilton Columbia Greystone

Sleep Inn Columbia

More cheap stays in South Carolina Midlands

Quality Inn Columbia Airport

Motel 6 Fort Mill, SC - Charlotte

Quality Inn Fort Jackson

Wyndham Garden Columbia/Ft. Jackson

Sleep Inn Columbia

Park Inn by Radisson Florence, SC

Hotels in South Carolina Midlands with star rating

Explore a world of travel with Expedia

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