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Isola Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Isola vacation rentals

A poolside area with two wooden lounge chairs and a clear view of the ocean.

1. Galatea e Giardino delle Esperidi apartments with pool by Wonderful Italy

Galatea e Giardino delle Esperidi apartments with pool by Wonderful Italy
Syracuse
The price is CA $181
CA $398 total
includes taxes & fees
Oct 30 - Oct 31
Galatea e Giardino delle Esperidi apartments with pool by Wonderful Italy
A terrace with outdoor furniture, including sofas and chairs, arranged around a central table.

2. Lanterne Magiche Ortigia

Lanterne Magiche Ortigia
Ortigia
9.4 out of 10, Exceptional, (272 reviews)
"We have no complaints. breakfast was excellent. The front desk was very helpful."
United States
Pablo
The price is CA $131
CA $150 total
includes taxes & fees
Nov 8 - Nov 9
Lanterne Magiche Ortigia
A modern living room with a sofa, a dining table with a lamp, and a coffee table. There are potted plants and a bookshelf in the background.

3. Archimede's Rooms

Archimede's Rooms
Neapolis
9.0 out of 10, Wonderful, (35 reviews)
"The only minus of the place is that there are no good restaurants in the area, you need to go back to city center."
United States
Stella
The price is CA $117
CA $133 total
includes taxes & fees
Oct 21 - Oct 22
Archimede's Rooms
A narrow street with a building featuring a pink awning and a sign for 'Aretusa Vacanze'.

4. Aretusa Vacanze B&B

Aretusa Vacanze B&B
1.0 star property
Ortigia
9.6 out of 10, Exceptional, (316 reviews)
"Great location & great hostess family"
United States
LILIYA
The price is CA $142
CA $162 total
includes taxes & fees
Nov 9 - Nov 10
Aretusa Vacanze B&B
A hotel entrance with a glass door, a staircase leading inside, and two potted trees on either side.

5. Residence Arco Antico

Residence Arco Antico
3.0 star property
Ortigia
9.0 out of 10, Wonderful, (114 reviews)
"Very good location, nice people and good price. I was worried about wifi, but worked fine and I was able to work and do all my calls."
United States
Alessandra
The price is CA $149
CA $170 total
includes taxes & fees
Oct 31 - Nov 1
Residence Arco Antico
A terrace with multiple tables and chairs, a tiled floor, and a view of the street and buildings in the background.

6. Affittacamere Il Terrazzo di Archimede

Affittacamere Il Terrazzo di Archimede
Neapolis
8.2 out of 10, Very good, (28 reviews)
"Great value and welcoming host for breakfast. Easily walkable to the sights of Siracusa and ortegia. Clean, comfortable and nice bathroom facilities."
United Kingdom
Stewart
The price is CA $81
CA $92 total
includes taxes & fees
Oct 30 - Oct 31
Affittacamere Il Terrazzo di Archimede
A coastal view with palm trees, a clear blue sea, and a grassy area with a pathway leading to a building.

7. Calapetra Resort

Calapetra Resort
Syracuse
9.6 out of 10, Exceptional, (112 reviews)
"The hotel staff was wonderful, informative and very accommodating. The beach was excellent. Breakfast was good, location was good. The beach was small but a little piece of heaven."
United States
Charlotte
The price is CA $164
CA $196 total
includes taxes & fees
Nov 15 - Nov 16
Calapetra Resort
A neatly made bed with a dark quilt, white pillows, and a beige headboard. There are two bedside lamps on either side of the bed.

8. Melody rooms

Melody rooms
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
The price is CA $55
CA $63 total
includes taxes & fees
Oct 22 - Oct 23
Melody rooms
A beach with clear turquoise water, sandy shore, and a distant rocky coastline with buildings.

9. Terra Mia Affittacamere

Terra Mia Affittacamere
3.0 star property
Melilli
9.6 out of 10, Exceptional, (25 reviews)
"Lovely location and great family business. Antonio was a perfect host and made me feel like part of the family. Home cooked fresh food and cold beers was great after a long day ! Clean tidy room and great price. Highly recommended ! "
United States
KEIRON
The price is CA $129
CA $142 total
includes taxes & fees
Oct 18 - Oct 19
Terra Mia Affittacamere
A terrace with white tables and chairs, white umbrellas, and a view of the sea.

10. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (134 reviews)
"We had an amazing time. Sabrina and Claudia were wonderful. The place is top notch in everything they do. The food was so fresh and delicious . I was sad when i had to leave them. High praise for this hotel. The views breath taking."
United States
Duane
The price is CA $297
CA $343 total
includes taxes & fees
Nov 7 - Nov 8
Giuggiulena Villa
A row of rectangular planters with green shrubs on a tiled floor, next to a building with windows and a wall-mounted light fixture.

11. Thalya Luxury Rooms

Thalya Luxury Rooms
3.0 star property
Syracuse
9.2 out of 10, Wonderful, (49 reviews)
"The property is very clean and well maintained"
United States
Kun
The price is CA $124
CA $141 total
includes taxes & fees
Nov 2 - Nov 3
Thalya Luxury Rooms
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees.

12. Casal Sikelio

Casal Sikelio
4.0 star property
Syracuse
10.0 out of 10, Exceptional, (33 reviews)
"This is an amazing property. The apartments are spacious and well laid out , the pool area is superb . Our host Antonino was excellent also."
United Kingdom
andrew
The price is CA $203
CA $232 total
includes taxes & fees
Oct 17 - Oct 18
Casal Sikelio
A rooftop lounge area with lounge chairs and a large potted plant.

13. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is CA $68
CA $114 total
includes taxes & fees
Oct 26 - Oct 27
Le Camere Luxsury Rooms
An outdoor dining area with a wooden table, chairs, hanging lanterns, and potted plants.

14. Alla Giudecca

Alla Giudecca
3.0 star property
Ortigia
8.4 out of 10, Very good, (292 reviews)
"Absolutely my favorite place we stayed in Sicily! Rooms were fabulous and the views were gorgeous! The restaurant was the most delicious of our entire week in Sicily! 10/10 ++++"
United States
katharine
The price is CA $88
CA $101 total
includes taxes & fees
Nov 8 - Nov 9
Alla Giudecca
A hotel room with a bed, desk, chair, and a potted plant.

15. SOCIAL HUB Siracusa

SOCIAL HUB Siracusa
Tiche
9.0 out of 10, Wonderful, (2 reviews)
"A very pleasant and helpful host. He took care of things if anything wasn't working. A spacious, comfortable room with a balcony. Close to the bus and a small breakfast café."
Norway
Paul Inge
The price is CA $85
CA $163 total
includes taxes & fees
Oct 17 - Oct 18
SOCIAL HUB Siracusa
A balcony with a hot tub, lounge chairs, and a view of the sunset over the water.

16. Palazzo Alfeo

Palazzo Alfeo
Ortigia
9.6 out of 10, Exceptional, (39 reviews)
"Incredible!! Brought our toddler and we were all able to spread out comfortably."
United States
Chelsea
The price is CA $453
CA $514 total
includes taxes & fees
Oct 31 - Nov 1
Palazzo Alfeo
A staircase leading to a room with a glass door, surrounded by potted plants.

17. Hotel Morfeo Residence

Hotel Morfeo Residence
3.0 star property
Syracuse
7.6 out of 10, Good, (28 reviews)
"The hotel is conveniently located. Everything is walkable. The hotel is quiet. The beds are however awful. Very very hard beds. The kitchen was not well stocked but had basics. "
United States
Gregory Allan
The price is CA $108
CA $124 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Morfeo Residence
A bedroom with a bed, two white chairs, a wooden headboard, a painting of a coastal scene, a lamp, and a nightstand with a lamp.

18. Elsa d'Ortigia - I TRE ARCHI

Elsa d'Ortigia - I TRE ARCHI
Ortigia
9.0 out of 10, Wonderful, (26 reviews)
"Excellent location, very friendly staff. Loved our stay."
United States
BERIL
The price is CA $210
CA $239 total
includes taxes & fees
Oct 18 - Oct 19
Elsa d'Ortigia - I TRE ARCHI
A table set for two with a view of the sea and boats in the background.

19. Dimore delle Zagare Molo

Dimore delle Zagare Molo
1.0 star property
Syracuse
9.8 out of 10, Exceptional, (10 reviews)
"The girl at the front desk was awesome She sent me on a great walking tour and had me go to a fantastic dinner with a 15% discount "
United States
Bart
The price is CA $197
CA $224 total
includes taxes & fees
Nov 16 - Nov 17
Dimore delle Zagare Molo
A rooftop pool with two hot tubs, a view of a historic building, and a sunset in the background.

20. Hotiday Apartments Siracusa

Hotiday Apartments Siracusa
Ortigia
8.8 out of 10, Excellent, (15 reviews)
"Location was perfect, very spacious, great shower comfortable bed. Checking in instructions via WhatsApp were simple and effective."
United Kingdom
Simon
The price is CA $113
CA $129 total
includes taxes & fees
Nov 16 - Nov 17
Hotiday Apartments Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isola Hotel Reviews

Hotel Porta Reale

Hotel Porta Reale

10/10 Excellent
"We had expected to visit Noto for only a few hours, but decided to stay overnight. How fortunate. This hotel is a gem. Very convenient to the main entrance to the historic old town, the hotel (inside) is very modern in a tasteful, contemporary way. Our welcome was very warm, and helpful. We were not in the main building but in a house just steps away. It was spacious. The bathroom was great -- well lit, terrific water power, and a spacious shower. In the main building there is a rooftop bar, and a free welcome drink was offered. It was a relaxing way to end a busy day. Tourist groups disappear at night, and it was quiet. There was a good selection of fruit, breads, cakes, yogurt, etc. at breakfast. I would definitely stay here again. And those travelling in Sicily by car might considering using Noto as a base to visit Siracusa and Ortygia."
Janice R 1-night trip
Posted 1 day ago
Hotel Porta Reale

Find out more about Isola

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Isola. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find a vacation rental in Isola?

Yes, you can find vacation rentals near the most popular sights in Isola, or you can choose a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental in Isola?

Guest House Ortigia Calarossa: This vacation home rental outside Isola has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Our travelers also rate With private tennis court, pool, 300m to the beach, WiFi, air con, max 7 guests as a favorite home for rent in Isola.

How many vacation rentals will I find in Isola?

Choose from 4 Expedia vacation rentals in Isola for a memorable vacation.

What can I see and do in Isola?

Ionian Sea and Spiaggia Punta del Pero are a couple of lovely local spots to get outside and enjoy nature. Tropical Aquarium of Syracuse and Cathedral of Syracuse are a couple of places you'll find in the larger area.

What are vacation rentals like in Isola?

Vacation rentals are private accommodations you can reserve for a short or long stay in Isola. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have everything you want. If you're concerned about cleanliness, a vacation rental can offer a sense of seclusion away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for families.