Title: Irene Vacation Packages & Trips 2025/2026 | Expedia.ca [Hotels in Irene](https://expedia.ca/Irene-Hotels.d3000353315.Travel-Guide-Hotels)[Vacation Rentals in Irene](https://expedia.ca/Irene-Vacation-Rentals.d3000353315.Travel-Guide-VacationRentals)[Irene Car Rentals](https://expedia.ca/Car-Rentals-In-Irene.d3000353315.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Irene Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence ### Better together Save up to CA $1,096 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Plan, book, and manage your trip all in one place ## Ready to book your vacation to Irene? Choose your dates ## Irene Hotel Deals ![Yankton Inn](https://images.trvl-media.com/lodging/1000000/860000/855600/855512/56ef74ee_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Yankton Inn 1603 East Highway 50, Yankton, SD Fully refundableReserve now, pay when you stay CA $113 CA $126 total Oct 12 - Oct 13 includes taxes & fees 7.4/10 Good! (256 reviews) "It is an older building hallways do not have air conditioning in hallways, bed was comfortable, nice breakfasts with protein's." Reviewed on Sep 23, 2025 [](https://expedia.ca/Hotel-Search?startDate=12%2F10%2F2025&endDate=13%2F10%2F2025&selected=855512&PinnedHotelID=855512&HadPinnedHotel=true®ionId=3000353315) ![Comfort Inn Yankton SD](https://images.trvl-media.com/lodging/11000000/10450000/10440200/10440162/70f394ec_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn Yankton SD 611 W 23rd Street, Yankton, SD Fully refundableReserve now, pay when you stay CA $142 CA $157 total Nov 9 - Nov 10 includes taxes & fees 8.8/10 Excellent! (634 reviews) "Fresh@Relaxing comes to mind" Reviewed on Oct 9, 2025 [](https://expedia.ca/Hotel-Search?startDate=09%2F11%2F2025&endDate=10%2F11%2F2025&selected=10440162&PinnedHotelID=10440162&HadPinnedHotel=true®ionId=3000353315) ![Lewis and Clark Resort](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/a76b5f6a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lewis and Clark Resort 43496 Shore Drive, Yankton, SD CA $121 CA $128 total Oct 30 - Oct 31 includes taxes & fees 8.6/10 Excellent! (264 reviews) "Great accommodations" Reviewed on Oct 6, 2025 [](https://expedia.ca/Hotel-Search?startDate=30%2F10%2F2025&endDate=31%2F10%2F2025&selected=11267995&PinnedHotelID=11267995&HadPinnedHotel=true®ionId=3000353315) [See all 82 properties in Irene](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=12%2F10%2F2025&endDate=13%2F10%2F2025®ionId=3000353315) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)