Title: Irene Vacation Packages & Trips 2025/2026 | Expedia.ca [Hotels in Irene](https://expedia.ca/Irene-Hotels.d3000353315.Travel-Guide-Hotels)[Vacation Rentals in Irene](https://expedia.ca/Irene-Vacation-Rentals.d3000353315.Travel-Guide-VacationRentals)[Irene Car Rentals](https://expedia.ca/Car-Rentals-In-Irene.d3000353315.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Irene Vacation Packages ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence ### Better together Save up to CA $1,096 when you book a flight and hotel together\* ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package ### Rest easy Plan, book, and manage your trip all in one place ## Ready to book your vacation to Irene? Choose your dates ## Irene Hotel Deals ![Comfort Inn Yankton SD](https://images.trvl-media.com/lodging/11000000/10450000/10440200/10440162/70f394ec_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Comfort Inn Yankton SD 611 W 23rd Street, Yankton, SD Fully refundableReserve now, pay when you stay CA $139 CA $154 total Nov 24 - Nov 25 includes taxes & fees 8.8/10 Excellent! (643 reviews) The staff was friendly and helpful, they let us check-in 1 hour early, they were great with kids, the room was clean except for what looked like a juice stain on the carpet. The heat worked great, it was quiet in the room, and the beds were comfortable. Breakfast had many different options, and the ... Reviewed on Oct 16, 2025 [](https://expedia.ca/Hotel-Search?startDate=24%2F11%2F2025&endDate=25%2F11%2F2025&selected=10440162&PinnedHotelID=10440162&HadPinnedHotel=true®ionId=3000353315) ![Lewis and Clark Resort](https://images.trvl-media.com/lodging/12000000/11270000/11268000/11267995/a76b5f6a_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Lewis and Clark Resort 43496 Shore Drive, Yankton, SD CA $145 CA $153 total Oct 30 - Oct 31 includes taxes & fees 8.6/10 Excellent! (269 reviews) nice place Reviewed on Oct 11, 2025 [](https://expedia.ca/Hotel-Search?startDate=30%2F10%2F2025&endDate=31%2F10%2F2025&selected=11267995&PinnedHotelID=11267995&HadPinnedHotel=true®ionId=3000353315) ![Best Western Kelly Inn](https://images.trvl-media.com/lodging/7000000/6850000/6847000/6846956/2110bd4e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Best Western Kelly Inn 1607 E Highway 50, Yankton, SD Fully refundableReserve now, pay when you stay CA $148 CA $164 total Nov 6 - Nov 7 includes taxes & fees 8/10 Very Good! (642 reviews) This was the perfect hotel for my family to stay in for a wedding. We enjoyed the breakfast, pool, and attached restaurant. I would stay there again. Reviewed on Oct 13, 2025 [](https://expedia.ca/Hotel-Search?startDate=06%2F11%2F2025&endDate=07%2F11%2F2025&selected=6846956&PinnedHotelID=6846956&HadPinnedHotel=true®ionId=3000353315) [See all 83 properties in Irene](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=30%2F10%2F2025&endDate=31%2F10%2F2025®ionId=3000353315) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## Explore a world of travel with Expedia \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app ![QR code to download the app](data:image/png;base64,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)