Isla Santa María Vacation Rentals

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Our top choices for Isla Santa María vacation rentals

Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
The price is CA $205
CA $232 total
May 20 - May 21
Galapagos Coliving Ecuador Casa Tuna

Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.2 out of 10, Wonderful, (23 reviews)
"Large apt with 2 large bedrooms and an equipped salon and kitchen."
United States
Alon
The price is CA $169
CA $169 total
May 20 - May 21
Torre Mar Galapagos Boutique Suites

¡Bienvenido a tu hogar isleño en Galápagos!

¡Bienvenido a tu hogar isleño en Galápagos!
Puerto Ayora
The price is CA $113
CA $140 total
Jun 19 - Jun 20
¡Bienvenido a tu hogar isleño en Galápagos!

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is CA $93
CA $121 total
May 31 - Jun 1
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is CA $86
CA $97 total
May 20 - May 21
Suites

Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (22 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is CA $155
CA $210 total
May 22 - May 23
Modern apartment with 18 feet ceilings and private terrace with view to a park

Torre Mar Galapagos Villa

Torre Mar Galapagos Villa
Puerto Ayora, Santa Cruz Island
10.0 out of 10, Exceptional, (1 review)
"We had a very nice time staying at Torre Mar. It was very conveniently located. We were 5 families...me (the mom) and my 4 kids, their spouses and 6 grandkids. Everyone had their own "suite". The advertising is a little confusing. I thought we were renting a "home", and then realized it was an apartment/hotel....but as I said, it was very nice for each family to have private space. The owner John was very friendly, although we did have some miscommunication issues, which is interesting...
United States
Betty A.
The price is CA $2,047
CA $2,320 total
Jun 1 - Jun 2
Torre Mar Galapagos Villa

KING-SIZE BED OR TWO TWIN BEDS SUITE ON SECOND FLOOR WITH CITY VIEW BALCONY

KING-SIZE BED OR TWO TWIN BEDS SUITE ON SECOND FLOOR WITH CITY VIEW BALCONY
Puerto Ayora
The price is CA $41
CA $75 total
May 20 - May 21
KING-SIZE BED OR TWO TWIN BEDS SUITE ON SECOND FLOOR WITH CITY VIEW BALCONY

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is CA $210
CA $298 total
May 30 - May 31
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Two Bedroom house - The Galapagos Pearl Hotel

Two Bedroom house - The Galapagos Pearl Hotel
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We stayed 3 nights in the "casa grande" associated with the Galapagos Pearl Hotel and could not have been more pleased. The casa has 2 bedrooms, a small kitchen, one bathroom, and is conveniently located right next to the pool and the outdoor dining area where Yolanda serves breakfast. Your room is cleaned every day. The garden surrounding the pool and casa is lush and full of geckos, cats, and beautiful plantings. Yolanda is from the Galapagos, she is a wonderful host and her daughter helped us...
United States
Laura E.
The price is CA $275
CA $346 total
May 21 - May 22
Two Bedroom house - The Galapagos Pearl Hotel

Imagination Studio Home

Imagination Studio Home
Puerto Ayora
The price is CA $357
CA $500 total
May 21 - May 22
Imagination Studio Home

Apartment near the Sea

Apartment near the Sea
PUERTO AYORA SANTA CRUZ GALAPAGOS
8.8 out of 10, Excellent, (5 reviews)
"Really nice place!"
United States
Sefora
The price is CA $110
CA $234 total
May 20 - May 21
Apartment near the Sea

KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR

KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR
Puerto Ayora
The price is CA $55
CA $91 total
May 20 - May 21
KING SIZE BED & TWIN SIZE BED WITH PRIVATE BATHROOM ON SECOND FLOOR

A nice place to stay with the family with spacious rooms

A nice place to stay with the family with spacious rooms
Puerto Ayora
The price is CA $37
CA $70 total
May 20 - May 21
A nice place to stay with the family with spacious rooms

Perfect for family or friends 4 Bedroom 2 bath

Perfect for family or friends 4 Bedroom 2 bath
Puerto Ayora, Santa Cruz Island
The price is CA $515
CA $587 total
Jun 1 - Jun 2
Perfect for family or friends 4 Bedroom 2 bath

Galarous Island Suite comfortable and cozy

Galarous Island Suite comfortable and cozy
Puerto Ayora
The price is CA $43
CA $70 total
May 21 - May 22
Galarous Island Suite comfortable and cozy

Five minutes from the Malecon Santa Cruz - Puerto Ayora.

Five minutes from the Malecon Santa Cruz - Puerto Ayora.
Puerto Ayora
The price is CA $179
CA $269 total
May 20 - May 21
Five minutes from the Malecon Santa Cruz - Puerto Ayora.

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Endemic Suite - Apartamento con Azotea Vista 360

Endemic Suite - Apartamento con Azotea Vista 360
Puerto Ayora
The price is CA $89
CA $117 total
Jun 2 - Jun 3
Endemic Suite - Apartamento con Azotea Vista 360

Comfortable Galarous Island Suite

Comfortable Galarous Island Suite
Puerto Ayora
The price is CA $240
CA $272 total
May 20 - May 21
Comfortable Galarous Island Suite
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Santa María Hotel Reviews

Find out more about Isla Santa María

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Isla Santa María. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Isla Santa María?

Yes, we have vacation rentals in Isla Santa María near Galápagos National Park, or you can go with a more secluded option if you're looking for extra privacy while you relax.

What are some of the best vacation rentals that Isla Santa María has to offer?

Villa Galapagos: Visitors like this Isla Santa María vacation home rental. It is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Isla Santa María?

Family-friendly attractions include Galápagos National Park, whereas Post Office Bay is a spot to enjoy the outdoors. Other places in town to visit include Punta Suarez.

What’s a vacation rental in Isla Santa María like?

Vacation rentals are private accommodations you can stay in for several days or longer in Isla Santa María. Vacation rentals provide amenities such as WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family trip.