Isla Santa María Vacation Rentals from CA $60: Short-Term Rentals for 2025

Q: What are some of the best vacation rentals that Isla Santa María has to offer?

Villa Galapagos : Visitors like this Isla Santa María vacation home rental. It is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

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Vacation Rentals in Isla Santa María

Relax by the pool in a spacious patio surrounded by lush greenery and a wooden pergola.

"Great stay! The rooms, the service, the breakfast, everything was great. Definitely stay here"

Superior Apartment, Bay View | Living area

Guests can enjoy a balcony with a railing and a window with a curtain, surrounded by lush plants.

"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"

CA $144 total

Jul 17 - Jul 18

Relax in a cozy hammock suspended from the ceiling, surrounded by natural light and a stylish, minimalist space.

CA $225 total

Aug 1 - Aug 2

Two single beds with patterned bedding, a sofa, and a wall-mounted artwork adorn this stylish room.

"Comfortable and easily accessible "

CA $71 total

Jul 17 - Jul 18

Stylish building with curved and straight lines, featuring multiple balconies with glass railings.

Relax in this serene outdoor patio surrounded by lush greenery and a rustic wooden table.

"Great room and a very walkable location. John was a fantastic host, has given me his whatsapp on day one and stayed in communication the whole time."

CA $147 total

Jul 17 - Jul 18

Enjoy cooking in this well-equipped kitchen with a granite countertop, dark cabinets, and a stainless steel refrigerator.

"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."

CA $308 total

Jul 17 - Jul 18

Relax in this stylish living room with a glass dining table, comfortable sofa, and flat-screen TV.

"Pilar was an excellent host. We are so happy that we found this place. Muchas gracias Pilar!"

Relax by the pool surrounded by a deck with comfortable seating and shade.

Enjoy cooking in this well-equipped kitchen with a central island, double oven, and ample dining space.

Cozy living space with two sofas, a bookshelf, and a potted plant.

CA $164 total

Aug 7 - Aug 8

Relax in this inviting space with a comfortable bed, nightstand, and dresser, perfect for unwinding.

Relax by the rectangular pool surrounded by lounge chairs and umbrellas.

"Really nice place!"

CA $233 total

Jul 17 - Jul 18

Relax in a serene patio surrounded by lush greenery and comfortable seating.

"We had a great time and are grateful to John and Donna for hosting us. The casita was very comfortable and quiet. Great wifi and air conditioning for when we needed to relax. Thank you again!"

CA $226 total

Jul 17 - Jul 18

Restful retreat with a neatly made bed, featuring a patterned bedspread and two pillows, a wooden headboard, and a nightstand with a lamp and remote control.

Enjoy casual dining at the Beer Bar, complete with a kitchen featuring a refrigerator, sink, and cooking appliances.

CA $133 total

Jul 20 - Jul 21

Enter a simple, functional room with a large window and a wooden stool in the corner.

Relax on the balcony with a view of the ocean, surrounded by lush greenery and comfortable seating.

"The apartment was spacious and well furnished. The view of the harbor was wonderful. "

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Find out more about Isla Santa María

Everything you need to know about Isla Santa María vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isla Santa María vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isla Santa María vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Isla Santa María vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Isla Santa María. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Isla Santa María vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Isla Santa María vacation rentals we have selected for you start as low as CA $60 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Isla Santa María rentals

At Expedia, we put the best Isla Santa María vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isla Santa María rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isla Santa María vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isla Santa María. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Recent reviews of Isla Santa María properties

5/5 Excellent

"Beautiful property, helpful staff, and quiet location."

A verified traveller stayed at Hotel Fiesta

Posted 4 days ago

5/5 Excellent

A colorful hidden gem in a central location

"For our first trip to the Galapagos, my two friends and I opted for the DIY style of exploring the Galapagos Islands. We wanted to stay at a place that was central to Puerto Ayora, small enough to not feel overwhelmed by tourists, and offered good recommendations for places to explore and restaurants to try. The staff at Maidith Inn delivered on all three! Maidith is a 5-10 minute walk to the busy shopping/dining scene and port from which the ferries depart, but far enough away from the busy street to be quiet at night. It had an intimate vibe, and Denis, the innkeeper for the time being, was there to greet us every morning and evening with kindness, fresh towels, and bottles of water. He provided great recommendations on restaurants to try in addition to the one-page list of dining options that Maidith had for its guests. When booking our reservation, I reached out to Maidith about some recommended places to visit on the way from the airport. For a reasonable price, they connected us with the best taxi driver who picked us up from the airport, took us to Los Gemelos, took us to Frontier Galapagos, where we saw land tortoises and hiked to/from the lava tunnels, and took us to the hotel. This taxi driver was incredibly kind and professional, and we ended up using his services two or three more times during our stay. As a plus, the daily breakfast is fresh and healthy. If traveling alone or with a small group, Maidith Inn could be the perfect option! "

A verified traveller stayed at Maidith Galapagos Inn

Posted 8 days ago

5/5 Excellent

"This was an oasis every day as we came back from our excursions. It is absolutely central and walkable within a 1 minute walk to restaurants, shops, and 3 min from the port, yet on a side street so peaceful. Capitan Max was accesible all the time providing info, making our breakfast, handing us towels and a backpack to the beach. The place is so beautifully decorated, the rooms even have a hammock, and the breakfasts are delicious and abundant. Also, there is always avail water, tea, hot cocoa, and bananas on the counter throughout the day. Everything was excellent!"

A verified traveller from Miami Beach stayed at Capitan Max B&B

Posted 9 days ago

Frequently asked questions

Can I find vacation rentals in Isla Santa María?

Yes, we have vacation rentals in Isla Santa María near Galápagos National Park, or you can go with a more secluded option if you're looking for extra privacy while you relax.

What are some of the best vacation rentals that Isla Santa María has to offer?

Villa Galapagos: Visitors like this Isla Santa María vacation home rental. It is located near the beach and offers a private yard, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Isla Santa María?

Family-friendly attractions include Galápagos National Park, whereas Post Office Bay is a spot to enjoy the outdoors. Other places in town to visit include Punta Suarez.

What’s a vacation rental in Isla Santa María like?

Vacation rentals are private accommodations you can stay in for several days or longer in Isla Santa María. Vacation rentals provide amenities such as WiFi and washers and dryers so you'll have all the comforts of home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy reception areas while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great choice for a family trip.

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Isla Santa María Vacation Rentals

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Vacation Rentals in Isla Santa María

Galapagos and Beyond

Galapagos and Beyond

Del mar del Galapagos

Del mar del Galapagos

Villa Galapagos

Villa Galapagos

Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna

Suites

Suites

Queen Bedroom Suite ON THE Second High Floor AT Ariana`s Galapagos Hostal

Queen Bedroom Suite ON THE Second High Floor AT Ariana`s Galapagos Hostal

Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites

FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora

Casa Marina, Darwin's dream in Galapagos

Casa Marina, Darwin's dream in Galapagos

Galapagos Cottages - Two-Bedroom House

Galapagos Cottages - Two-Bedroom House

Oasis for upscale travelers seeking a private home-away-from-home in Galapagos

Oasis for upscale travelers seeking a private home-away-from-home in Galapagos

Lovely House.

Lovely House.

Odessa - Galapagos Minisuite 500 ft From THE Ocean #2

Odessa - Galapagos Minisuite 500 ft From THE Ocean #2

Apartment near the Sea

Apartment near the Sea

Cozy, spacious and quiet 3 bedroom apartment in preferred location on Beach path

Cozy, spacious and quiet 3 bedroom apartment in preferred location on Beach path

Island Life Two Bedroom Galapagos Casita

Island Life Two Bedroom Galapagos Casita

Odessa - Galapagos Minisuite 500 ft From THE Ocean #3

Odessa - Galapagos Minisuite 500 ft From THE Ocean #3

Charming studio in Puerto Ayora with all the services for a comfortable stay

Charming studio in Puerto Ayora with all the services for a comfortable stay

Rich to Rest !!!come and enjoy Galapagos

Rich to Rest !!!come and enjoy Galapagos

Modern and spacious loft with ocean view

Modern and spacious loft with ocean view

Find out more about Isla Santa María

Find out more about Isla Santa María

Recent reviews of Isla Santa María properties

Recent reviews of Isla Santa María properties

Hotel Fiesta

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Explore a world of travel with Expedia

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