Hannibal Vacation Packages
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Your Hannibal Vacation
Excellent adventures await when you lock in a vacation package to Hannibal. Whether you're a history buff, foodie or just a traveler who loves to experience new places, there's something for everyone in this exciting city. Fill your spare time with tours of Mark Twain Boyhood Home and Museum, Mark Twain Cave and Cameron Cave and Mark Twain Cave, some of the attractions you shouldn't miss during your trip to Hannibal. Stop daydreaming and start traveling. Explore the broad range of options on Expedia today and put your Hannibal vacation plans into gear!
Top Hannibal Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield
Price was CA $2,147, price is now CA $1,557 per person
CA $1,557
per person
Mar 21 - Mar 28
found 16 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again.
Reviewed on Dec 22, 2025
The Cheshire
Price was CA $1,993, price is now CA $1,527 per person
CA $1,527
per person
Mar 19 - Mar 26
found 16 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
The Cheshire is in a class by itself. The halls and sitting areas are so full of history and there’s an ambiance that we just love. Our suite, Treasure Island, was amazing! Large, clean, luxurious and cozy with a beautiful fireplace and large jacuzzi. We had a delicious dinner at the Basso, relaxed in the very British, cozy Fox & Hound, enjoyed a coffee at the Tudor styled Starbucks and as always, enjoyed breakfast beside the fireplace. We loved our stay!
Reviewed on Jan 28, 2026
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
Price was CA $2,048, price is now CA $1,605 per person
CA $1,605
per person
Mar 19 - Mar 26
found 16 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to St. Louis (STL)
8.8/10 Excellent! (1,022 reviews)
It was good and beautiful on the inside. Loved all the art. The bed was comfy and the room was like an apartment .The only thing that stunk is that there wasn't a microwave in the room. But there was one on the floor so it worked out.
Reviewed on Feb 3, 2026
Hannibal Hotel Deals
Quality Inn & Suites Hannibal West
120 Lindsey Drive Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $90 per night from Feb 19 to Feb 20
CA $90
CA $105 total
Feb 19 - Feb 20
includes taxes & fees
8/10 Very Good! (1,003 reviews)
I was very pleased with our stay. The hotel text me within hours of checking in just to make sure we didnt need anything. Ive never had that happen before. They allowed us to switch our rooms so they would be connecting. They even let us check in a little early. Last of all the pool is pretty nice ...
Reviewed on Feb 1, 2026
Sleep Inn & Suites Hannibal West
105 Lakeside Dr Hannibal MO
Fully refundable
The price is CA $135 per night from Feb 15 to Feb 16
CA $135
CA $156 total
Feb 15 - Feb 16
includes taxes & fees
9.6/10 Exceptional! (1,002 reviews)
Beds were comfortable. Breakfast was good
Reviewed on Jan 25, 2026
Best Western On The River
401 North 3rd Street Hannibal MO
Fully refundableReserve now, pay when you stay
The price is CA $111 per night from Feb 8 to Feb 9
CA $111
CA $128 total
Feb 8 - Feb 9
includes taxes & fees
8.6/10 Excellent! (1,000 reviews)
We had an issue with our Expedia reservation. Tony was professional & provided excellent customer service fixing the issue.
Reviewed on Feb 2, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Hannibal
Mark Twain Boyhood Home and Museum
Find out about the history of Hannibal when you take a trip to Mark Twain Boyhood Home and Museum. While in this walkable area, you can savor the top-notch restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
