Greenville Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*
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Top Greenville Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Hilton Pennywell St. Louis at the Arch
The Mercantile on the Katy Trail
 The Royal Sonesta Chase Park Plaza St. Louis
21C Museum Hotel St Louis
Four Seasons Hotel St Louis

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Greenville Hotel Deals

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

2.5 out of 5
2265 S. State Route 127 Greenville IL
Fully refundable
The price is CA $160 per night from Jul 20 to Jul 21
CA $160
CA $178 total
Jul 20 - Jul 21
includes taxes & fees
8.4/10 Very good! (451 reviews)
"Breakfast was good. Well stocked and appetizing."

Reviewed on Jul 2, 2026

Comfort Inn & Suites Greenville I-70
Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

2 out of 5
1700 State Route 127 Greenville IL
Fully refundableReserve now, pay when you stay
The price is CA $93 per night from Jul 19 to Jul 20
CA $93
CA $103 total
Jul 19 - Jul 20
includes taxes & fees
8/10 Very good! (814 reviews)
"We got 2 rooms and one smelled awful, but I didn't know till the next day bc"

Reviewed on Jul 8, 2026

Super 8 by Wyndham Greenville
SureStay Hotel by Best Western Greenville

SureStay Hotel by Best Western Greenville

2.5 out of 5
1731 S State Route 127 Greenville IL
Fully refundableReserve now, pay when you stay
The price is CA $86 per night from Jul 16 to Jul 17
CA $86
CA $96 total
Jul 16 - Jul 17
includes taxes & fees
7.4/10 Good! (589 reviews)
"Nice basic place to spend a night. We didn’t have time to swim, but pool looked fine. Breakfast options were pretty good (cereal, muffins, bagels, yogurt, fruit, MYO waffles) except that the juice in the dispenser was old, not spoiled but stale/dirty tasting. We wondered if the tap water was safe ..."

Reviewed on Jul 7, 2026

SureStay Hotel by Best Western Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Greenville attractions

Frequently asked questions

How much does a Greenville vacation package cost?
You can pick up a vacation package to this top destination from CA $1,150 on Expedia. But how much your vacation to Greenville costs will depend on factors like the season, length of stay and hotel choice.
What are the cheapest months to go to Greenville?
January, February and November are great times to look for cheap Greenville vacation packages. Opting to travel in less busy periods means you can typically find better prices on hotels and flights.
How many days is enough for Greenville?
With a well-planned itinerary, you can easily visit the top Greenville attractions in a handful of days. But if you prefer to venture off the beaten track or go on day tours, consider booking your Greenville vacation for longer.
How to find the best Greenville package deals?
Begin your search for a Greenville package deal by entering your preferred trip dates and destination under our "Packages" tab. Then apply a few filters, like "Property type" and "Amenities," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with big savings. If you don't find the perfect Greenville package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Greenville escape underway.
Is it cheaper to book a Greenville vacation as a package?
An Expedia vacation package could land you considerable savings when compared to booking flights and hotels individually. Better still, you can customize your Greenville getaway to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to Greenville?
Enjoy incredible discounts by reserving your flights early with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for an impromptu Greenville trip.
How to plan a trip to Greenville?

  1. Choose when to get away: Check your schedule and pack your bags. Your preferred time of year and the type of activities on offer will also help you decide when to visit Greenville.
  2. Figure out your budget: Ensure you have enough money to pay for everything from food and transportation to flights and activities. Your accommodations will probably be the biggest expense during your trip to Greenville.
  3. Decide how many days away: Start by listing all the attractions you'd like to get to in Greenville. Then, estimate how long you'll need at each, including any travel time.
  4. Bundle your bookings: With your travel dates in place, you can combine your flights, car rental, hotels and more into a personalized Greenville vacation package.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.