Title: 10 Best Hotels in Grand Isle, Port St. Joe for 2025 | Expedia.ca [Vacation Rentals in Port St. Joe](https://expedia.ca/Port-St-Joe-Vacation-Rentals.d147606.Travel-Guide-VacationRentals)[Flights to Port St. Joe](https://expedia.ca/Cheap-Flights-To-Port-St-Joe.d147606.Travel-Guide-Flights)[Things to do in Port St. Joe](https://expedia.ca/Things-To-Do-In-Port-St-Joe.d147606.Travel-Guide-Activities)[Grand Isle Car Rentals](https://expedia.ca/Car-Rentals-In-Grand-Isle.d553248635976473803.Car-Rental-Guide)[Grand Isle Vacations](https://expedia.ca/Grand-Isle.d553248635976473803.Destination-Travel-Guides) ![John Gorrie Memorial Bridge over Apalachicola Bay at sunset, Florida, USA](https://images.trvl-media.com/place/553248635976473803/511c6003-47bb-4762-966a-d67b2e85164d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Hotels in Grand Isle, Port St. Joe ![calendar shield illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![bed illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Grand Isle Ocean view [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=OCEAN_VIEW) Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=APARTMENT) Cottage [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=COTTAGE) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=PETS) Condo [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&lodging=CONDO) Waterpark [](https://www.expedia.ca/Hotel-Search?destination=Grand+Isle%2C+Mexico+Beach%2C+Florida%2C+United+States+of+America®ionId=553248635976473803&latLong=29.944542%2C-85.408171&adults=2&startDate=2025-10-22&d1=2025-10-22&endDate=2025-10-24&d2=2025-10-24&amenities=WATER_PARK) ## Check prices for these dates Tonight [Oct 8 - Oct 9](https://www.expedia.ca/Hotel-Search?regionId=553248635976473803&startDate=2025-10-08&endDate=2025-10-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 9 - Oct 10](https://www.expedia.ca/Hotel-Search?regionId=553248635976473803&startDate=2025-10-09&endDate=2025-10-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 10 - Oct 12](https://www.expedia.ca/Hotel-Search?regionId=553248635976473803&startDate=2025-10-10&endDate=2025-10-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 17 - Oct 19](https://www.expedia.ca/Hotel-Search?regionId=553248635976473803&startDate=2025-10-17&endDate=2025-10-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Recommended Price (low to high) Distance Star rating ## Grand Isle hotels and places to stay ![Exterior](https://images.trvl-media.com/lodging/11000000/10250000/10250000/10249974/183f6bd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/11000000/10250000/10250000/10249974/96fa7a39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, individually decorated](https://images.trvl-media.com/lodging/11000000/10250000/10250000/10249974/026be2f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/11000000/10250000/10250000/10249974/58deae55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Port Inn and Cottages, an Ascend Collection Hotel Downtown Port St. Joe, 17.9 km from Grand Isle 9.0/10 Wonderful (388) "Check in staff was great! Cute little place in the perfect location to explore downtown PSF on foot." CA $153 CA $171 total includes taxes & fees Oct 27 - Oct 28 [](https://www.expedia.ca/Panama-City-Hotels-The-Port-Inn-And-Cottages.h10249974.Hotel-Information) ![Suite, Multiple Beds, Accessible, Non Smoking](https://images.trvl-media.com/lodging/2000000/1600000/1593000/1592956/a663df02.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1600000/1593000/1592956/99767f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1600000/1593000/1592956/d7c1d65a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/2000000/1600000/1593000/1592956/438cbc2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### MainStay Suites Port Saint Joe South 22.1 km from Grand Isle 8.6/10 Excellent (678) "The hotel is a little older but it was clean and the rooms were a nice size." CA $153 CA $171 total includes taxes & fees Oct 19 - Oct 20 [](https://www.expedia.ca/Panama-City-Hotels-MainStay-Suites.h1592956.Hotel-Information) ![Laptop workspace, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/110000/101000/100931/36e74a8c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/110000/101000/100931/e2b0b121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/110000/101000/100931/a265cb1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast area](https://images.trvl-media.com/lodging/1000000/110000/101000/100931/a8e3efea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Panama City/Callaway 29.4 km from Grand Isle 6.8/10 (466) "Room was clean and the staff was friendly and helpful." CA $85 CA $92 total includes taxes & fees Oct 22 - Oct 23 [](https://www.expedia.ca/Panama-City-Hotels-Days-Inn-By-Wyndham-Panama-CityCallaway.h100931.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111242900/111242857/ea59c233.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/112000000/111250000/111242900/111242857/c42615b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room](https://images.trvl-media.com/lodging/112000000/111250000/111242900/111242857/b02a5f2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/112000000/111250000/111242900/111242857/b1e0e9d6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Panama City Tyndall AFB by IHG 28.7 km from Grand Isle 9.6/10 Exceptional (27) "The room was great, the staff was friendly and helpful. " CA $162 CA $175 total includes taxes & fees Oct 10 - Oct 11 [](https://www.expedia.ca/Panama-City-Hotels-Candlewood-Suites-Panama-City-Tyndall-AFB.h111242857.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21520000/21513200/21513188/4cdb5473.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/22000000/21520000/21513200/21513188/d32baae9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily breakfast](https://images.trvl-media.com/lodging/22000000/21520000/21513200/21513188/f84d7660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, Ensuite (Coquina Shell)](https://images.trvl-media.com/lodging/22000000/21520000/21513200/21513188/3db34614.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cape San Blas Inn 27 km from Grand Isle 9.8/10 Exceptional (79) "Great host excellent location we will be back" [](https://www.expedia.ca/Panama-City-Hotels-Cape-San-Blas-Inn.h21513188.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/4000000/3130000/3123200/3123136/86b29f51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/4000000/3130000/3123200/3123136/2706ef6f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/4000000/3130000/3123200/3123136/4fe69a24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/4000000/3130000/3123200/3123136/ab0346e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites 29 km from Grand Isle 8.6/10 Excellent (699) "Bed were comfortable " CA $132 CA $143 total includes taxes & fees Oct 14 - Oct 15 [](https://www.expedia.ca/Panama-City-Hotels-Comfort-Suites.h3123136.Hotel-Information) ![Free buffet breakfast](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427795/658ada8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427795/58caa71d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427795/6ff4e0e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1430000/1427800/1427795/df29bde4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG 29.1 km from Grand Isle 8.4/10 Very good (435) "Thank you Jacob and Charlie for all your help with the air conditioning, and all the staff excellent service. My family and I enjoyed the stay." CA $127 CA $137 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Panama-City-Hotels-Holiday-Inn-Express-Hotel-Suites-Panama-City-Tyndall.h1427795.Hotel-Information) ![Standard Studio, Non Smoking, Refrigerator & Microwave](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723208/ecb02ab5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full-size fridge, microwave, stovetop, freezer](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723208/72aabbc9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723208/6bc52649.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1730000/1723300/1723208/b772fe68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Extended Stay America Select Suites - Panama City - Callaway 30.1 km from Grand Isle 6.2/10 (492) "great stay" CA $99 CA $107 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Panama-City-Hotels-WoodSpring-Suites-Panama-City.h1723208.Hotel-Information) ![Aerial view](https://images.trvl-media.com/lodging/117000000/116010000/116004400/116004319/2891923e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage, 2 Bedrooms, Resort View (Scallop) | Living area](https://images.trvl-media.com/lodging/117000000/116010000/116004400/116004319/facccec2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/117000000/116010000/116004400/116004319/87b4fd3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cottage, 2 Bedrooms, Resort View (Pelican) | Private kitchen](https://images.trvl-media.com/lodging/117000000/116010000/116004400/116004319/e53a1343.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cape Cottages by Panhandle Getaways 22.8 km from Grand Isle 10/10 Exceptional (3) "Brand new, quaint spot with really comfortable beds. " CA $227 CA $822 total includes taxes & fees Oct 9 - Oct 10 [](https://www.expedia.ca/Port-St-Joe-Hotels-Cape-Cottages-By-Panhandle-Getaways.h116004319.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-10-22&endDate=2025-10-23®ionId=553248635976473803&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FGrand-Isle-Port-St-Joe-Hotels.0-n553248635976473803-0.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FGrand-Isle-Port-St-Joe-Hotels.0-n553248635976473803-0.Travel-Guide-Filter-Hotels) ## Where to stay in Grand Isle Find the best Grand Isle areas and neighborhoods for the activities you enjoy most. - Downtown Port St. Joe - Cape Breezes - Gulf Aire - Waterside Village - Palms [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=904317974476165120) ![Downtown Port St. Joe map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7Dn%7EtD%7EqugO%7D%40mzBxlD%7DiA%7DFzeAYj%7D%40em%40%7BHaYtDia%40pAsNrLoOfY%7DFnNoOjJ&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=JHh5yyAZHzmZCpqdk_5qLy82jmQ=) ### Downtown Port St. Joe While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=904317974476165120) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976480659) ![Cape Breezes map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ekntDbsehOFm%60%40bJ%7D%40tIgBSp%5CmT%60H&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=WVakQWTal7I1aXGuY4rRGK_cpzA=) ### Cape Breezes While Cape Breezes isn't home to many top sights, T.H. Stone Memorial St. Joseph Peninsula State Park and St. Joseph Peninsula State Park are some notable places to visit nearby. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976480659) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976480970) ![Gulf Aire map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:ypquDvlbhO_OyS%3FoPdSp%40GoM%7EBy%40nEfHqErFhGjJ%5EhFePnP&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=XF9Cno-DZ77uz5roYnODX_-9Kuo=) ### Gulf Aire While Gulf Aire isn't home to many top sights, Saint Joe Beach and Mexico Beach are some notable places to visit nearby. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976480970) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976471619) ![Waterside Village map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7DsxuDtyjhOcBmAiByEjAc%40bCjEnCmF_%40c%40Tc%40jAhAsEjJ&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=69hRPskCkcK035DvYY0BSD8fSEM=) ### Waterside Village Though Waterside Village might not have many top sights, you can venture to the surrounding area to see attractions like Mexico Beach Marina and Mexico Beach. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976471619) [](https://www.expedia.ca/Hotel-Search?pwaOverlay=map®ionId=553248635976469185) ![Palms map](https://maps.googleapis.com/maps/api/staticmap?&size=289x340&map_id=c017d89749dc74ad&markers=icon:%7C&path=enc:%7D%7CwuDhjfhOAmCpUMAfCmUR&key=AIzaSyAoVHdVOa5-BDRxGhFoAHYIHPst1T09Jo0&signature=MfczdQ9YyhPafotKPOJ2Hu3qgmM=) ### Palms While there might not be top attractions in Palms, you can explore the larger area and discover places like Mexico Beach and Mexico Beach Marina. [See properties](https://www.expedia.ca/Hotel-Search?regionId=553248635976469185) ## Top Grand Isle Hotel Reviews ![Days Inn by Wyndham Panama City/Callaway](//images.trvl-media.com/lodging/1000000/110000/101000/100931/36e74a8c_y.jpg) ### Days Inn by Wyndham Panama City/Callaway 10/10 Excellent "Smoothe" [](https://expedia.ca/Panama-City-Hotels-Days-Inn-By-Wyndham-Panama-CityCallaway.h100931.Hotel-Information) ![The Port Inn and Cottages, an Ascend Collection Hotel](//images.trvl-media.com/lodging/11000000/10250000/10250000/10249974/183f6bd6_y.jpg) ### The Port Inn and Cottages, an Ascend Collection Hotel 10/10 Excellent "Extremely attentive and engaging" [](https://expedia.ca/Panama-City-Hotels-The-Port-Inn-And-Cottages.h10249974.Hotel-Information) ![100 STEPS TO BEACH, PETS OK, RENOVATED, VERY CLEAN, N. CAPE, DISCOUNTED RATES!!](//images.trvl-media.com/lodging/67000000/66490000/66488100/66488084/6e8404de_y.jpg) ### 100 STEPS TO BEACH, PETS OK, RENOVATED, VERY CLEAN, N. CAPE, DISCOUNTED RATES!! 10/10 Excellent "What an amazing place. Perfect for a couple or two. We took two of our Golden Retrievers with us and had a blast. The house is well named as it’s 100 steps to the Gulf of America. The photos on the listing don’t do the actual place justice. It’s so comfortable and has everything you need with a great porch, two queen beds, two baths, a great kitchen with a huge great room and eating area. The host is so responsive to all texts and emails - we’ve even referred a friend. The sunsets are beautiful and I cannot more highly recommend this spot! We’ll be back. " [](https://expedia.ca/Port-St-Joe-Hotels-100-STEPS-TO-BEACH.h66488084.Hotel-Information) ![Mexico Beach Condo steps from the beach! ~Snowbird Rates Available~](//images.trvl-media.com/lodging/90000000/89800000/89797200/89797113/7f722dc5_y.jpg) ### Mexico Beach Condo steps from the beach! ~Snowbird Rates Available~ 10/10 Excellent "Great unit. Super clean and nicely decorated. Beach is just steps away. Caleb was quickly responsive to messages. Definitely recommend. " [](https://expedia.ca/Port-St-Joe-Hotels-Brand-New-Mexico-Beach-Condo-Steps-From-The-Beach.h89797113.Hotel-Information) ![Candlewood Suites Panama City Tyndall AFB by IHG](//images.trvl-media.com/lodging/112000000/111250000/111242900/111242857/ea59c233_y.jpg) ### Candlewood Suites Panama City Tyndall AFB by IHG 10/10 Excellent "The room was great, the staff was friendly and helpful. " [](https://expedia.ca/Panama-City-Hotels-Candlewood-Suites-Panama-City-Tyndall-AFB.h111242857.Hotel-Information) ![Beach Front! Magical Stay on the Water! Two king beds, Book Summer Dates Now!](//images.trvl-media.com/lodging/79000000/78080000/78072400/78072344/d60fb4ff_y.jpg) ### Beach Front! Magical Stay on the Water! Two king beds, Book Summer Dates Now! 10/10 Excellent "Great condo right on the Gull! Had everything we needed including coffee and counter top ice maker. Furnishings and bed were very comfortable and amenities exceeded our expectations. Jill was great to with. Mentioned that love bugs were visiting us on the upper deck and the next day they didn't come back." [](https://expedia.ca/Port-St-Joe-Hotels-Cape-San-Blas.h78072344.Hotel-Information) ![Need A Vacation? Relax at Salty Latitude](//images.trvl-media.com/lodging/54000000/53970000/53963600/53963525/3ee5833a_y.jpg) ### Need A Vacation? Relax at Salty Latitude 10/10 Excellent "We had a great time " [](https://expedia.ca/Port-St-Joe-Hotels-Need-A-Vacation-Relax-At-Salty-Latitude.h53963525.Hotel-Information) ![MainStay Suites Port Saint Joe South](//images.trvl-media.com/lodging/2000000/1600000/1593000/1592956/a663df02_y.jpg) ### MainStay Suites Port Saint Joe South 10/10 Excellent "The hotel called after we left to inform us of something we left behind. They mailed it back to us! All of the staff were so helpful and friendly. The hotel had beautiful surroundings and was near everything we wanted to do." [](https://expedia.ca/Panama-City-Hotels-MainStay-Suites.h1592956.Hotel-Information) ![Beachfront Condo/Pool at Surfside. Best view too! Perfect 2BR/2BA Sleeps 6 ](//images.trvl-media.com/lodging/34000000/33750000/33743700/33743680/8955cd85_y.jpg) ### Beachfront Condo/Pool at Surfside. Best view too! Perfect 2BR/2BA Sleeps 6 10/10 Excellent "The unit has a wonderful view of the beach. I would definitely stay here again. " [](https://expedia.ca/Port-St-Joe-Hotels-Beachfront-Condo-At-Surfside-Perfect-2BR2BA-Sleeps-6-722-729-200000.h33743680.Hotel-Information) ## Frequently asked questions ### What is Grand Isle like? > Travelers to Mexico Beach's Grand Isle neighborhood will be sure to enjoy a stay in this neighborhood. ### How many hotels will I find in Grand Isle? > Expedia has 8 Grand Isle hotels and other accommodations, and one might make a good home base for venturing out into the greater Mexico Beach area. ### If I need to cancel my hotel reservation in Grand Isle, will I receive a refund? > Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Isle. ### What is there to do around this Mexico Beach neighborhood? > Places you might want to visit in the area around Grand Isle include Mexico Beach and Mexico Beach Marina. 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[Things to do in Port St. Joe](https://www.expedia.ca/Things-To-Do-In-Port-St-Joe.d147606.Travel-Guide-Activities) - [Book Hotels in Grand Isle on Expedia.com](https://www.expedia.com/Grand-Isle-Port-St-Joe-Hotels.0-n553248635976473803-0.Travel-Guide-Filter-Hotels) - Explore a world of travel with Expedia ### Hotels in top Port St. Joe neighborhoods - [Hotels in Downtown Port St. Joe](https://expedia.ca/Downtown-Port-St-Joe-Port-St-Joe-Hotels.0-n904317974476165120-0.Travel-Guide-Filter-Hotels) - [Hotels in Cape Breezes](https://expedia.ca/Cape-Breezes-Port-St-Joe-Hotels.0-n553248635976480659-0.Travel-Guide-Filter-Hotels) - [Hotels in Gulf Aire](https://expedia.ca/Gulf-Aire-Port-St-Joe-Hotels.0-n553248635976480970-0.Travel-Guide-Filter-Hotels) - [Hotels in Waterside Village](https://expedia.ca/Waterside-Village-Port-St-Joe-Hotels.0-n553248635976471619-0.Travel-Guide-Filter-Hotels) - [Hotels in Grand Isle](https://expedia.ca/Grand-Isle-Port-St-Joe-Hotels.0-n553248635976473803-0.Travel-Guide-Filter-Hotels) - [Hotels in Palms](https://expedia.ca/Palms-Port-St-Joe-Hotels.0-n553248635976469185-0.Travel-Guide-Filter-Hotels) ### Hotels near popular Port St. Joe Attractions - [Hotels near Tyndall Air Force Base Visitor Center](https://expedia.ca/Tyndall-Air-Force-Base-Visitor-Center-Hotels.0-l6127813-0.Travel-Guide-Filter-Hotels) - [Hotels near Mexico Beach](https://expedia.ca/Mexico-Beach-Hotels.0-l553248621532653527-0.Travel-Guide-Filter-Hotels) - [Hotels near Tyndall Air Force Base](https://expedia.ca/Tyndall-Air-Force-Base-Hotels.0-l553248635975869278-0.Travel-Guide-Filter-Hotels) - [Hotels near Saint Joe Beach](https://expedia.ca/Saint-Joe-Beach-Hotels.0-l553248635975749237-0.Travel-Guide-Filter-Hotels) - [Hotels near St. Andrews Bay](https://expedia.ca/St-Andrews-Bay-Hotels.0-l553248635976472870-0.Travel-Guide-Filter-Hotels) - [Hotels near Windmark Beach](https://expedia.ca/Windmark-Beach-Hotels.0-l6185503-0.Travel-Guide-Filter-Hotels) - [Hotels near St. Joseph Peninsula State Park](https://expedia.ca/St-Joseph-Peninsula-State-Park-Hotels.0-l6294786-0.Travel-Guide-Filter-Hotels) - [Hotels near Money Bayou](https://expedia.ca/Money-Bayou-Hotels.0-l553248635976197201-0.Travel-Guide-Filter-Hotels) - [Hotels near Chipola River](https://expedia.ca/Chipola-River-Hotels.0-l684513323905392640-0.Travel-Guide-Filter-Hotels) - [Hotels near T.H. Stone Memorial St. Joseph Peninsula State Park](https://expedia.ca/TH-Stone-Memorial-St-Joseph-Peninsula-State-Park-Hotels.0-l553248622207644934-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Grand Isle - [Vacation Homes in Port St. Joe](https://expedia.ca/Port-St-Joe-Private-Vacation-Homes.d147606-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Condo Rentals in Port St. Joe](https://expedia.ca/Port-St-Joe-Condos.d147606-aaCondos.Travel-Guide-Accommodation) - [Apartments in Port St. Joe](https://expedia.ca/Port-St-Joe-Apartments.d147606-aaApartments.Travel-Guide-Accommodation) - [Cottages in Port St. Joe](https://expedia.ca/Port-St-Joe-Cottages.d147606-aaCottages.Travel-Guide-Accommodation) - [RV Parks in Port St. Joe](https://expedia.ca/Port-St-Joe-RV-Parks.d147606-aaRVParks.Travel-Guide-Accommodation) - [Townhomes in Port St. Joe](https://expedia.ca/Port-St-Joe-Townhomes.d147606-aaTownhomes.Travel-Guide-Accommodation) - [Villas in Port St. Joe](https://expedia.ca/Port-St-Joe-Villas.d147606-aaVillas.Travel-Guide-Accommodation) - [B&B in Port St. Joe](https://expedia.ca/Port-St-Joe-Bed-And-Breakfast.d147606-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Cabin Rentals in Port St. Joe](https://expedia.ca/Port-St-Joe-Cabins.d147606-aaCabins.Travel-Guide-Accommodation) - [Guest Houses in Port St. Joe](https://expedia.ca/Port-St-Joe-Guest-Houses.d147606-aaGuestHouses.Travel-Guide-Accommodation) ### Grand Isle Hotels by Star Rating - [2 Star Hotels in Grand Isle](https://expedia.ca/2Star-Grand-Isle-Port-St-Joe-Hotels.s20-n553248635976473803-0.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Grand Isle](https://expedia.ca/3Star-Grand-Isle-Port-St-Joe-Hotels.s30-n553248635976473803-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Grand Isle](https://expedia.ca/4Star-Grand-Isle-Port-St-Joe-Hotels.s40-n553248635976473803-0.Travel-Guide-Filter-Hotels) ### Grand Isle Hotels by Brand - [Independent Hotels](https://expedia.ca/Grand-Isle-Port-St-Joe-Hotels-Independent.0-n553248635976473803-0--bIndependent.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Waterfront on N. CSB, Dog-friendly, Amazing Views!](https://expedia.ca/Port-St-Joe-Hotels-Waterfront-On-N-CSB.h76542629.Hotel-Information) - [Gulf Front Family Beach House:Heated Pool:Hot Tub:Outdoor Game Tables](https://expedia.ca/Port-St-Joe-Hotels-Family-Beach-HouseHeated-PoolHot-TubOutdoor-Pool-TableShuffleboardFoosball.h60662700.Hotel-Information) - [The Shipwreck Cottage is your beach vacation spot!](https://expedia.ca/Port-St-Joe-Hotels-The-Shipwreck-Cottage-Is-Your-Beach-Vacation-Spot.h78073347.Hotel-Information) - [Dog-friendly beach house with a private pool, firepit, AC, & washer/dryer](https://expedia.ca/Port-St-Joe-Hotels-Dog-Friendly-Beach-House-With-A-Private-Pool.h97304618.Hotel-Information) - [Luxury Gulf-Front Retreat. Heated Pool, Pet-Friendly. September Price Drops](https://expedia.ca/Port-St-Joe-Hotels-YOU-NAME-IT-NOW-RENTING-FOR-SUMMER-Gulf-Front-Heated-Pool-Steps-To-Beach.h75272379.Hotel-Information) - [Beachfront Condo/Pool at Surfside. Best view too! Perfect 2BR/2BA Sleeps 6](https://expedia.ca/Port-St-Joe-Hotels-Beachfront-Condo-At-Surfside-Perfect-2BR2BA-Sleeps-6-722-729-200000.h33743680.Hotel-Information) - [Beach Front! Magical Stay on the Water! Two king beds, Book Summer Dates Now!](https://expedia.ca/Port-St-Joe-Hotels-Cape-San-Blas.h78072344.Hotel-Information) - [Brand new 3BR/2Bath condo with rooftop pool/hot tub on very quiet beach](https://expedia.ca/Port-St-Joe-Hotels-Brand-New-3BR2Bath-Condo-With-Rooftop-Poolhot-Tub-On-Very-Quiet-Beach.h99734596.Hotel-Information) - [SEA SHANTY- Beachfront, Topnotch Comfort & Fully-Stocked!](https://expedia.ca/Port-St-Joe-Hotels-SEA-SHANTY-Beachfront.h82662056.Hotel-Information) - [GULF VIEW! 🌊☀️Steps from beach!! 3 bedroom 3.5 bath](https://expedia.ca/Port-St-Joe-Hotels-Mexico-Beach-Fl.h112146731.Hotel-Information) - [Captain Roy's -- A treasure on the beach
Beachfront, Beachfront, Beachfront
](https://expedia.ca/Port-St-Joe-Hotels-Captain-Roys-A-Treasure-On-The-Beach.h78284710.Hotel-Information) - [6 bd/5.5 ba designer coastal oasis w/ private pool - Sleeps 18 on North CSB](https://expedia.ca/Port-St-Joe-Hotels-6-Bd55-Ba-Designer-Coastal-Oasis-W-Private-Pool-Sleeps-18-On-North-CSB.h116848022.Hotel-Information) [See a list of all hotels in Port St. Joe](https://expedia.ca/All-Port-St-Joe-Hotels.d147606.Travel-Guide-City-All-Hotels) ### More ways to book - [Book Hotels in Grand Isle on Expedia.com](https://www.expedia.com/Grand-Isle-Port-St-Joe-Hotels.0-n553248635976473803-0.Travel-Guide-Filter-Hotels) ### Expedia's Latest Trends Hotels - [Brickell hotels](https://expedia.ca/Brickell-Miami-Hotels.0-n6240961-0.Travel-Guide-Filter-Hotels) - [Downtown Tampa hotels](https://expedia.ca/Downtown-Tampa-Tampa-Hotels.0-n6048134-0.Travel-Guide-Filter-Hotels) - [Coconut Grove hotels](https://expedia.ca/Coconut-Grove-Miami-Hotels.0-n11937-0.Travel-Guide-Filter-Hotels) - [Doral hotels](https://expedia.ca/Doral-Miami-Hotels.0-n6060126-0.Travel-Guide-Filter-Hotels) - [Downtown Miami hotels](https://expedia.ca/Downtown-Miami-Miami-Hotels.0-n800070-0.Travel-Guide-Filter-Hotels) - [Downtown Orlando hotels](https://expedia.ca/Downtown-Orlando-Orlando-Hotels.0-n800087-0.Travel-Guide-Filter-Hotels) - [Wynwood Art District hotels](https://expedia.ca/Wynwood-Art-District-Miami-Hotels.0-n6240011-0.Travel-Guide-Filter-Hotels) - [Cheap Hotels in South Beach](https://expedia.ca/South-Beach-Miami-Hotels-Cheap-Hotels.0-n6138745-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Boutique Hotels in South Beach](https://expedia.ca/South-Beach-Miami-Hotels-Boutique-Hotel.0-n6138745-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - [Little Havana hotels](https://expedia.ca/Little-Havana-Miami-Hotels.0-n505226-0.Travel-Guide-Filter-Hotels) - [South Beach 5 Star Hotels](https://expedia.ca/5Star-South-Beach-Miami-Hotels.s50-n6138745-0.Travel-Guide-Filter-Hotels) - [South Beach hotels](https://expedia.ca/South-Beach-Miami-Hotels.0-n6138745-0.Travel-Guide-Filter-Hotels) - [Beach Hotel in South Beach](https://expedia.ca/South-Beach-Miami-Hotels-Beach-Hotel.0-n6138745-0-tBeachHotel.Travel-Guide-Filter-Hotels) - [Mid Beach hotels](https://expedia.ca/Mid-Beach-Miami-Hotels.0-n6203154-0.Travel-Guide-Filter-Hotels) - [Oceanfront Hotels in South Beach](https://expedia.ca/South-Beach-Miami-Hotels-Oceanfront-Hotels.0-n6138745-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels) Packages - [South Beach Vacations](https://expedia.ca/South-Beach.d6138745.Destination-Travel-Guides) General - [Visit Downtown Orlando](https://expedia.ca/Orlando-Downtown-Orlando.dx800087) - [Visit Galt Mile](https://expedia.ca/Fort-Lauderdale-Galt-Mile.dx553248635976473854) - [Visit Siesta Key Village](https://expedia.ca/Siesta-Key-Siesta-Key-Village.dx6296072) - [Visit South Beach](https://expedia.ca/Miami-South-Beach.dx6138745) - [Visit North Beach](https://expedia.ca/Miami-North-Beach.dx6203157) - [Visit Sunset Beach](https://expedia.ca/St-Petersburg-Clearwater-Sunset-Beach.dx6159959) - [Visit Downtown Miami](https://expedia.ca/Miami-Downtown-Miami.dx800070) - [Visit Biltmore Beach](https://expedia.ca/Panama-City-Beach-Biltmore-Beach.dx553248635976471384) - [Visit Downtown Fort Lauderdale](https://expedia.ca/Fort-Lauderdale-Downtown-Fort-Lauderdale.dx800035) - [Visit Wynwood Art District](https://expedia.ca/Miami-Wynwood-Art-District.dx6240011) - [Visit Hollywood Beach](https://expedia.ca/Fort-Lauderdale-Hollywood-Beach.dx553248635975850057) - [Visit Little Havana](https://expedia.ca/Miami-Little-Havana.dx505226) - [Visit Coconut Grove](https://expedia.ca/Miami-Coconut-Grove.dx11937) - [Visit Brickell](https://expedia.ca/Miami-Brickell.dx6240961)