Florence

Travel Guide

Florence

Explore the historic buildings and museums of this delightful South Carolina city that’s also known for its nature trails and outdoor pursuits.

The city of Florence is an alluring vacation spot for its blend of cultural and natural attractions. Here you can journey through swamplands, learn about Native American heritage and study artifacts from the Civil War.

Familiarize yourself with the history of ”Flo-town” by exploring its old buildings. Visit the Queen Anne-style Levy House that was home to the city’s first black physician. Stop by Henry Timrod Schoolhouse, the one-room timber building constructed in 1859. Study the collections of Florence’s museums. See railroad memorabilia in the Florence Railroad Museum and examine weapons and uniforms from the Civil War at the War Between the States Museum.

Florence lies close to the Pee Dee River and is surrounded by farmland. Take advantage of this scenic setting for a range of outdoor pursuits. Canoe through cypress swamplands on the 66-mile (106.2-kilometer) SC Revolutionary Rivers Trail. The route starts at Lynches River County Park where you can take a canopy walk high up among the trees. Take the Clemson Outdoor Education Trail to a Native American village and butterfly garden. Look out for tree frog retreats on the nature trail at Wallace Woods.

If you play golf, hit a ball at Florence’s golf courses, including the Country Club of South Carolina and Crossings Golf Club. More sporting activities are on offer over at the Freedom Florence Recreational Complex.

You will find lots of restaurants in Florence, which serve everything from fast food to gourmet dishes. Satisfy your craving for Southern food with specialties such as fried chicken, fried okra and pecan pie. 

Get to the city by bus, train or car, or by flying into the Florence Regional Airport. A rental car, taxi or public transport can get you around. The Pee Dee Regional Transportation Authority operates buses throughout the region. Just an hour away from Florence is Myrtle Beach, a popular coastal city with watersports and miles of sandy beaches.

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 out of 5
1729 Mandeville Road, Florence, SC
The price is CA $116 per night from Sep 1 to Sep 2
CA $116
CA $129 total
Sep 1 - Sep 2
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and the ...
9/10 Wonderful! (2,110 reviews)
"Worked well for a 1 night stay. The breakfast area was not kept up well or restocked while we were there."

Reviewed on Aug. 6, 2025

Park Inn by Radisson Florence, SC
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2 out of 5
2038 W Lucas Street, I-95 Exit 164, Florence, SC
The price is CA $97 per night from Aug 10 to Aug 11
CA $97
CA $108 total
Aug 10 - Aug 11
includes taxes & fees
Book a stay at this business-friendly motel in Florence. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (2,327 reviews)
"This is my 3rd time staying here. The Rooms always clean and bathroom also. The rooms could use some renovations but other than that, it’s a good place to stop to divide a trip from NJ to FL or visa versa. Can’t beat the price. Always a quick check in."

Reviewed on Aug. 7, 2025

Howard Johnson by Wyndham Florence
Comfort Inn & Suites

Comfort Inn & Suites

2.5 out of 5
527 Woody Jones Blvd, Florence, SC
The price is CA $147 per night from Aug 24 to Aug 25
CA $147
CA $165 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Florence. Enjoy free breakfast, free WiFi, and an outdoor pool. Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,048 reviews)
"I’ve stated this property two or three times on my travels to Florida and back. My room was quiet, comfortable, and bad comfortable Breakfast was good."

Reviewed on Aug. 7, 2025

Comfort Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cozy log cabin with plenty of space in Florence, SC

Cozy log cabin with plenty of space in Florence, SC

Florence
Stay at this cabin in Florence. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker. Popular attraction Eastern Carolina Agricultural Fairgrounds ...
9.6/10 Exceptional! (65 reviews)
"This home is beautifully furnished and clean. Situated on a large flat lot and fenced in yard. Owners were easy to deal with and very accommodating. We will certainly be renting this home again!!Dave"

Reviewed on Jul. 23, 2025

Cozy log cabin with plenty of space in Florence, SC
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's

Florence
Stay at this vacation home in Florence. Enjoy laundry facilities, an in-room coffeemaker, and in-room fireplaces. Popular attractions Regal Swamp Fox and Florence ...
10/10 Exceptional! (25 reviews)
"It was absolutely beautiful and very clean! They provided everything one could think of to make the stay comfortable and enjoyable. I’m already looking forward to booking this place again next year. I highly recommend it!"

Reviewed on Aug. 3, 2025

Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's
Hickory Haven 3Br Elegant Downtown Hidden Gem

Hickory Haven 3Br Elegant Downtown Hidden Gem

Florence
Book a stay at this family-friendly vacation home in Florence. Enjoy laundry facilities, cable/satellite TV service, and an in-room coffeemaker. Popular attractions ...
9.6/10 Exceptional! (18 reviews)
Great Home
"This home was perfect for our family. Would definitely recommend to anyone looking for a place to stay in the Florence area."

Reviewed on Jul. 6, 2025

Hickory Haven 3Br Elegant Downtown Hidden Gem
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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