A desert landscape with layered rock formations, a prominent rock pillar, and distant mountains under a clear sky.

Mesa County Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in Mesa County

A river winding through a valley with a large solar farm and a mountain in the background.
Vacation RentalsVacation Rentals

Grand Junction

Grand Junction

Our top choices for Mesa County vacation rentals

Room

1. Camp Eddy

Camp Eddy
2.0 star property
Pear Park
9.4 out of 10, Exceptional, (445 reviews)
"This was the perfect spot for an overnight stay. Close to downtown Grand Junction. Very cool place, would stay here again."
United States
Kaitlyn
The price is CA $75
CA $161 total
includes taxes & fees
Nov 9 - Nov 10
Camp Eddy
A multi-story residential building with a mix of siding and brickwork, a front porch, and a visible entrance door.

2. Dtwn Walkability! Grand Junction Couple's Retreat

Dtwn Walkability! Grand Junction Couple's Retreat
3.0 star property
Downtown
10.0 out of 10, Exceptional, (4 reviews)
"Our stay was fantastic! The location was perfect—close to everything. The property was clean and loved the decor. The host was super responsive and helpful, making our trip stress-free. Highly recommend!"
United States
renee
The price is CA $161
CA $371 total
includes taxes & fees
Oct 26 - Oct 27
Dtwn Walkability! Grand Junction Couple's Retreat
A kitchenette with a coffee machine, a small refrigerator, and a coffee cup holder with disposable cups and a coffee pod.

3. 1 Queen Bed | Non-Smoking

1 Queen Bed | Non-Smoking
Horizon Drive District
10.0 out of 10, Exceptional, (48 reviews)
"Close to airport, super easy check-in process!"
United States
Anonymous traveller
The price is CA $83
CA $96 total
includes taxes & fees
Nov 1 - Nov 2
1 Queen Bed | Non-Smoking
A kitchen with teal cabinets, a stainless steel dishwasher, and a black countertop.

4. Unique downtown Fruita apartment with bike storage!

Unique downtown Fruita apartment with bike storage!
Fruita
10.0 out of 10, Exceptional, (65 reviews)
"Great place to stay. Very clean, spacious, and safe with an excellent location for the bike trails and walking to dinner. We will definitely be back."
United States
Kimberly
The price is CA $112
CA $246 total
includes taxes & fees
Oct 26 - Oct 27
Unique downtown Fruita apartment with bike storage!
A small wooden cabin with a black roof, two windows, and a view of a lake and hills in the background.

5. Redlands Tiny Home

Redlands Tiny Home
Redlands
10.0 out of 10, Exceptional, (3 reviews)
"Very clean little cabin with wonderful views! Host was great. Nice little patch of grass for Mia. Octillia restaurant at the golf course was amazing!"
United States
Clare J.
The price is CA $73
CA $187 total
includes taxes & fees
Oct 26 - Oct 27
Redlands Tiny Home
A bedroom with a bed, a ceiling fan, a marble artwork, bedside lamps, a small bedside table with a plant, and a mirror.

6. 2 bedroom apartment in Downtown Fruita with bike storage!

2 bedroom apartment in Downtown Fruita with bike storage!
Fruita
9.8 out of 10, Exceptional, (45 reviews)
"Great little place."
United States
Dorthy W.
The price is CA $145
CA $284 total
includes taxes & fees
Oct 27 - Oct 28
2 bedroom apartment in Downtown Fruita with bike storage!
A modern living room with a black leather sofa, a white coffee table, and a dining area with a blue table and two chairs.

7. Redlands Casita

Redlands Casita
Redlands
9.8 out of 10, Exceptional, (6 reviews)
"Nice area, nice amenities. Perfect for our needs in Grand Junction."
United States
Bonnie F.
The price is CA $67
CA $211 total
includes taxes & fees
Oct 26 - Oct 27
Redlands Casita
A kitchen with wooden cabinets, a refrigerator, a microwave, a coffee maker, and a sink.

8. Charming country studio close to Fruita and biking trails

Charming country studio close to Fruita and biking trails
Fruita
10.0 out of 10, Exceptional, (28 reviews)
"very charming place to stay. the view when you walk out of the red mountains is amazing."
United States
Cynthia
The price is CA $126
CA $167 total
includes taxes & fees
Nov 3 - Nov 4
Charming country studio close to Fruita and biking trails
A modern building with a sloped roof, a concrete pathway, and a gravel area in front.

9. Visit Tres Chivos Farmhouse warm and cozy, Kids and pet friendly too!

Visit Tres Chivos Farmhouse warm and cozy, Kids and pet friendly too!
Grand Junction
10.0 out of 10, Exceptional, (324 reviews)
"It's a nice place to stay."
United States
Stephen G.
The price is CA $164
CA $279 total
includes taxes & fees
Nov 1 - Nov 2
Visit Tres Chivos Farmhouse warm and cozy, Kids and pet friendly too!
A modern living room with a sofa, coffee table, and a chair near large windows.

10. Restored 2BR Historic Cottage w/ Mesa Views – Grand Junction

Restored 2BR Historic Cottage w/ Mesa Views – Grand Junction
Redlands
10.0 out of 10, Exceptional, (22 reviews)
"Quaint and peaceful with amazing views. This place was so clean! We enjoyed our stay very much!"
United States
LaDonna C.
The price is CA $139
CA $265 total
includes taxes & fees
Oct 29 - Oct 30
Restored 2BR Historic Cottage w/ Mesa Views – Grand Junction
A spacious living area with a wooden ceiling, a dining table with chairs, a black leather sofa, and a patterned rug.

11. The Carriage House

The Carriage House
Pear Park
10.0 out of 10, Exceptional, (193 reviews)
"Great place to stay, hosts are ready to help as needed. We will consider using it again as we have family in town."
United States
Dorit h.
The price is CA $125
CA $231 total
includes taxes & fees
Oct 26 - Oct 27
The Carriage House
A cozy cabin interior with a leather sofa, wooden walls, and a dining area.

12. 'ali River Farms' Breathtaking Mt Backdrop!

'ali River Farms' Breathtaking Mt Backdrop!
3.0 star property
Clifton
The price is CA $297
CA $646 total
includes taxes & fees
Oct 26 - Oct 27
'ali River Farms' Breathtaking Mt Backdrop!
A modern living room with a grey sofa, a round coffee table, and a bookshelf.

13. Launch your Colorado adventures – Historic Downtown convenience

Launch your Colorado adventures – Historic Downtown convenience
East Main Street
10.0 out of 10, Exceptional, (123 reviews)
"Very clean nice house for the family vacation. Adam is a great host. The location of the house is perfect for a Grand Junction vacation."
United States
Brian
The price is CA $126
CA $289 total
includes taxes & fees
Oct 28 - Oct 29
Launch your Colorado adventures – Historic Downtown convenience
A rustic cabin with a wooden deck, a small porch, and a bar area with stools.

14. Stagecoach Cabin - antique western charm

Stagecoach Cabin - antique western charm
Collbran
10.0 out of 10, Exceptional, (25 reviews)
"Great place!"
United States
Hugh T.
The price is CA $139
CA $175 total
includes taxes & fees
Oct 26 - Oct 27
Stagecoach Cabin - antique western charm
A living room with a brown leather sofa, wooden coffee table, and a TV on a blue cabinet.

15. Farmhouse in the country

Farmhouse in the country
Grand Junction
10.0 out of 10, Exceptional, (20 reviews)
"We really enjoyed our stay! Peaceful & had everything needed for a nice visit."
United States
Mark W.
The price is CA $167
CA $369 total
includes taxes & fees
Oct 26 - Oct 27
Farmhouse in the country
A street view of a historic downtown area with brick buildings, storefronts, and a clear sky.

16. My Home Cottage Near CMU & Downtown, Workspace

My Home Cottage Near CMU & Downtown, Workspace
Hawthorne Park
9.8 out of 10, Exceptional, (204 reviews)
"It was a pleasant and cozy place to stay for a night while visiting my uncle at Hilltop. The back patio was very nice to relax in the evening."
United States
Jesse F.
The price is CA $159
CA $478 total
includes taxes & fees
Oct 26 - Oct 27
My Home Cottage Near CMU & Downtown, Workspace
A compact living space with a sofa, a small dining table with stools, and a bedroom with a bed.

17. Cozy Updated Apartment Walking Distance to Downtown Fruita

Cozy Updated Apartment Walking Distance to Downtown Fruita
Fruita
9.6 out of 10, Exceptional, (14 reviews)
"Great location for easy walking to town. Very small unit, but perfect for a couple. Clean and bike-friendly. Bed was super comfortable. Reasonably priced and we would stay again for sure."
United States
Diana H.
The price is CA $129
CA $246 total
includes taxes & fees
Nov 2 - Nov 3
Cozy Updated Apartment Walking Distance to Downtown Fruita
A living room with a fireplace, a sofa, and a dining area with chairs.

18. Historic, Charming GJ Downtown tiny home- Best location!

Historic, Charming GJ Downtown tiny home- Best location!
Washington Park
9.8 out of 10, Exceptional, (41 reviews)
"Charming little place in a quiet area. Walking distance from downtown GJ and CMU! Nice yard and patio area too."
United States
Sally C.
The price is CA $175
CA $373 total
includes taxes & fees
Oct 26 - Oct 27
Historic, Charming GJ Downtown tiny home- Best location!
A single-story house with a blue door, a welcome mat, and a small porch with two chairs.

19. Charming cottage minutes away from Downtown

Charming cottage minutes away from Downtown
Grand Junction
9.6 out of 10, Exceptional, (13 reviews)
"Cute place, felt very comfortable and cozy inside and it was great to have a backyard to play in and a park nearby. The kitchen and bath were thoughtfully appointed and it was great to have off street parking."
United States
Leah M.
The price is CA $175
CA $445 total
includes taxes & fees
Oct 26 - Oct 27
Charming cottage minutes away from Downtown
A round table with two plates and a wine glass, surrounded by wicker chairs, under a red umbrella, with a view of a fenced area and trees.

20. Views in Every Direction, Adjoins Golf, minutes to Miles of Bike & Hiking trails

Views in Every Direction, Adjoins Golf, minutes to Miles of Bike & Hiking trails
Fruita
10.0 out of 10, Exceptional, (38 reviews)
"Absolutely great accommodations in a very beautiful and convenient area. Check in was seemless and easy."
United States
Dathan
The price is CA $169
CA $488 total
includes taxes & fees
Nov 4 - Nov 5
Views in Every Direction, Adjoins Golf, minutes to Miles of Bike & Hiking trails
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mesa County Hotel Reviews

Ville 718

Ville 718

10/10 Excellent
"I enjoyed my stay I will be staying there again."
Dwight 1-night trip
Posted 4 hours ago
Ville 718

Find out more about Mesa County

Everything you need to know about Mesa County vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Mesa County vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesa County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Mesa County vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesa County. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Mesa County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Mesa County vacation rentals we have selected for you start as low as CA $161 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Mesa County rentals

At Expedia, we put the best Mesa County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Mesa County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesa County vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesa County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.