A wooden suspension bridge surrounded by dense green foliage.

Search Florence County Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Top Cities in Florence County

Check prices for these dates

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Florence County hotels

1. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,504 reviews)
"Great place to spend the night during our road trip. Would stay again."
United States
Susan
The price is CA $127
CA $143 total
includes taxes & fees
Nov 22 - Nov 23
Park Inn by Radisson Florence, SC

2. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,399 reviews)
"The room was very clean, the beds very comfortable and the pillows as well. Highly recommended."
United States
Jana
The price is CA $143
CA $160 total
includes taxes & fees
Nov 30 - Dec 1
Comfort Inn & Suites Florence Center Area

3. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.4 out of 10, Very good, (358 reviews)
"Great staff easy Check in I love staying here!!!"
United States
Alanya
The price is CA $137
CA $162 total
includes taxes & fees
Nov 17 - Nov 18
Spark by Hilton Florence North I-95, SC

4. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,761 reviews)
"Quiet clean and inexpensive stay, especially relative to neighboring locations"
United States
Carl
The price is CA $91
CA $102 total
includes taxes & fees
Nov 11 - Nov 12
Howard Johnson by Wyndham Florence

5. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.4 out of 10, Good, (1,014 reviews)
"Good rooms for the price"
United States
Louis
The price is CA $93
CA $104 total
includes taxes & fees
Dec 6 - Dec 7
Days Inn by Wyndham Florence Near Civic Center

6. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,005 reviews)
"Great location"
United States
Delouris
The price is CA $164
CA $184 total
includes taxes & fees
Nov 15 - Nov 16
Hyatt Place Florence Downtown

7. The Inn at the Crossroads

The Inn at the Crossroads
2.0 star property
Lake City
9.6 out of 10, Exceptional, (1,005 reviews)
"Excellent stay. A little overpriced for the area. But nice hotel."
United States
Winston
The price is CA $154
CA $173 total
includes taxes & fees
Dec 10 - Dec 11
The Inn at the Crossroads

8. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
8.4 out of 10, Very good, (429 reviews)
"Will recommend nice & quiet will be visiting again"
United States
Franklin
The price is CA $126
CA $141 total
includes taxes & fees
Nov 17 - Nov 18
Quality Inn & Suites Florence Civic Center

9. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Good location, clean room and good breakfast."
United States
NOORUDIN
The price is CA $161
CA $180 total
includes taxes & fees
Nov 22 - Nov 23
Hampton Inn & Suites Florence Center

10. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
Florence
8.2 out of 10, Very good, (1,002 reviews)
"Staff is so helpful hotel is very clean well kept"
United States
Tom
The price is CA $145
CA $171 total
includes taxes & fees
Nov 12 - Nov 13
SpringHill Suites by Marriott Florence

11. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (929 reviews)
"Fabulous pet-friendly place to stay."
United States
Ralph
The price is CA $155
CA $173 total
includes taxes & fees
Nov 22 - Nov 23
TownePlace Suites by Marriott Florence

12. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice and clean hotel"
United States
HANH
The price is CA $161
CA $180 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

13. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.6 out of 10, Excellent, (1,002 reviews)
"Great hotel and staff"
United States
Margarita
The price is CA $155
CA $182 total
includes taxes & fees
Nov 17 - Nov 18
Tru by Hilton Florence I-95

14. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay great breakfast clean"
United States
Zachary
The price is CA $172
CA $193 total
includes taxes & fees
Dec 6 - Dec 7
Staybridge Suites Florence - Civic Center by IHG

15. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,456 reviews)
"Close to the restaurants and shopping."
United States
Brenda
The price is CA $126
CA $141 total
includes taxes & fees
Nov 22 - Nov 23
La Quinta Inn & Suites by Wyndham Florence

16. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (659 reviews)
"The house keeping people"
United States
WILLIE
The price is CA $196
CA $219 total
includes taxes & fees
Nov 22 - Nov 23
Hotel Florence, Tapestry Collection by Hilton

17. Florence Inn and Suites

Florence Inn and Suites
2.5 star property
Florence
6.8 out of 10, (444 reviews)
"This hotel is horrible"
United States
Latonya
The price is CA $74
CA $83 total
includes taxes & fees
Nov 22 - Nov 23
Florence Inn and Suites

18. Comfort Suites Florence I-95

Comfort Suites Florence I-95
2.5 star property
Florence
8.2 out of 10, Very good, (1,001 reviews)
"Our room was very clean and quiet. The staff was excellent and the breakfast was very good. They did charge us a $5.95 fee for the use of the amenities, gym, pool and breakfast located at the property."
United States
Michael
The price is CA $155
CA $187 total
includes taxes & fees
Dec 7 - Dec 8
Comfort Suites Florence I-95

19. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (1,002 reviews)
"Excellente hotel, clean, good breakfast, and quiet."
Canada
chantal
The price is CA $161
CA $180 total
includes taxes & fees
Nov 24 - Nov 25
Hampton Inn & Suites Florence-North-I-95

20. Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.2 out of 10, Good, (1,007 reviews)
"Great and affordable stay"
United States
Shawn
The price is CA $77
CA $86 total
includes taxes & fees
Nov 22 - Nov 23
Super 8 by Wyndham Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Florence County, SC

Showing deals for:Nov 20 - Nov 22

Save an average of 15% on thousands of hotels when you're signed in

Top Florence County Hotel Reviews

Explore a world of travel with Expedia