Title: Defiance Vacation Rentals from CA $291: Short-Term Rentals for 2026 | Expedia.ca [Hotels in Defiance](https://expedia.ca/Defiance-Hotels.d6353634.Travel-Guide-Hotels)[Flights to Defiance](https://expedia.ca/Cheap-Flights-To-Defiance.d6353634.Travel-Guide-Flights)[Defiance Car Rentals](https://expedia.ca/Car-Rentals-In-Defiance.d6353634.Car-Rental-Guide)[Defiance Vacation Packages](https://expedia.ca/Defiance.d6353634.Destination-Travel-Guides) ![A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6353634/33b2b915-0d1b-4946-ae10-3b89e88434a7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates In two weeks [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 22 - May 24](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [Jun 19 - Jun 21](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jul 17 - Jul 19](https://www.expedia.ca/Hotel-Search?regionId=6353634&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Defiance vacation rentals ![Interior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/5d45ed4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/46f64c9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/7d7d40ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062608/0589f65d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Adorable Augusta Cabin [](https://www.expedia.ca/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information) Augusta 8.6/10 Excellent (13 reviews) "Absolutely beautiful area. Cabin is so cozy" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron CA $123 CA $291 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Augusta-Hotels-Adorable-Augusta-Cabin.h110062608.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/d4de2daa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/0aa09261.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/216e0674.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/45000000/44130000/44124700/44124669/03086e89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pet and kid friendly duplex with 2 bedrooms [](https://www.expedia.ca/Pacific-Hotels-Pet-And-Kid-Friendly-Duplex-With-2-Bedrooms.h44124669.Hotel-Information) Pacific 9.6/10 Exceptional (47 reviews) "Such a wonderful weekend. We had everything we needed. Lovely spot! Thank you" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveller CA $185 CA $240 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/Pacific-Hotels-Pet-And-Kid-Friendly-Duplex-With-2-Bedrooms.h44124669.Hotel-Information) ![Smart TV](https://images.trvl-media.com/lodging/94000000/93610000/93608300/93608223/f64528bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/94000000/93610000/93608300/93608223/27a515ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/94000000/93610000/93608300/93608223/d097c082.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/94000000/93610000/93608300/93608223/d2c2d0b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Historic WashMo home [](https://www.expedia.ca/Washington-Hotels-Cozy-Historic-WashMo-Home.h93608223.Hotel-Information) Washington 9.2/10 Wonderful (27 reviews) "Lovely stay, well done on the updates of the house. Upstairs is a little cold, but otherwise it was a great weekend rental. Close to the river, so easy walking " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Valerie R. CA $154 CA $356 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Washington-Hotels-Cozy-Historic-WashMo-Home.h93608223.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/w905h683x60y0-7da69c98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/f45a4107.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/w507h683x260y0-03493f60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/72000000/71510000/71507600/71507563/ca1dea43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### TJ’s Country Getaway- Dog Friendly [](https://www.expedia.ca/Union-Hotels-TJs-Country-Getaway.h71507563.Hotel-Information) Union 10/10 Exceptional (47 reviews) "Wonderful property, clean and very quiet!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lindsay J. CA $97 CA $221 total includes taxes & fees Apr 26 - Apr 27 [](https://www.expedia.ca/Union-Hotels-TJs-Country-Getaway.h71507563.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/1e8558f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/a7d9ee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/5ed26783.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/111000000/110070000/110062700/110062605/b7b6310c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Rustic Augusta Wood Cabin [](https://www.expedia.ca/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information) Augusta 9.2/10 Wonderful (5 reviews) "I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) teresa s. CA $161 CA $429 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/Augusta-Hotels-Rustic-Augusta-Cabin-By-StayLage.h110062605.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/8d0398a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/107ec1ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/08562f32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, books](https://images.trvl-media.com/lodging/104000000/103900000/103890100/103890008/4c428d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL [](https://www.expedia.ca/Augusta-Hotels-WELCOME-TO-THE-OWLS-NEST-2-BEDROOM-HOME-IN-AUGUSTA.h103890008.Hotel-Information) Augusta 10/10 Exceptional (31 reviews) "Adorable place to stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amy F. CA $224 CA $406 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Augusta-Hotels-WELCOME-TO-THE-OWLS-NEST-2-BEDROOM-HOME-IN-AUGUSTA.h103890008.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/24b502b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/5c3f47e7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/5b625011.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/35000000/34820000/34814500/34814455/a62878f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Aspen Heights by Innsbrook Vacations! [](https://www.expedia.ca/Wright-City-Hotels-Aspen-Heights-By-Innsbrook-Vacations.h34814455.Hotel-Information) Innsbrook 9.0/10 Wonderful (10 reviews) "Nice, quiet, relaxing place to stay! Great communication with the host. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lorna M. CA $108 CA $320 total includes taxes & fees Mar 27 - Mar 28 [](https://www.expedia.ca/Wright-City-Hotels-Aspen-Heights-By-Innsbrook-Vacations.h34814455.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/100000000/99230000/99228400/99228367/11f8c334.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, offices](https://images.trvl-media.com/lodging/100000000/99230000/99228400/99228367/66bd6a04.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/100000000/99230000/99228400/99228367/d121d846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/100000000/99230000/99228400/99228367/83c4f82b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fragrance free - spacious Ranch -safe &quiet- 4 br 2 bath [](https://www.expedia.ca/St-Louis-Hotels-Fragrance-Free-Spacious-Ranch-Safe-Quiet-4-Br-2-Bath.h99228367.Hotel-Information) High Ridge 9.4/10 Exceptional (30 reviews) "The Host was in contact throughout the stay and was always making sure we had everything we needed. Nice place and great Hosts!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frank G. CA $275 CA $532 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/St-Louis-Hotels-Fragrance-Free-Spacious-Ranch-Safe-Quiet-4-Br-2-Bath.h99228367.Hotel-Information) ![TV, fireplace](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/w2033h1365x15y0-e5f03757.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, desk, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/90fd5cd3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/adda266d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/111000000/110320000/110319600/110319519/bc9c69f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Blake Cottage Wine Country Home [](https://www.expedia.ca/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information) Augusta 8.4/10 Very good (9 reviews) "We loved the cottage and the town of Augusta. Would definitely stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyler S. CA $196 CA $545 total includes taxes & fees Apr 6 - Apr 7 [](https://www.expedia.ca/Augusta-Hotels-The-Marigold-Cottage-By-StayLage.h110319519.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/35000000/34830000/34822200/34822185/48d89c57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/35000000/34830000/34822200/34822185/618dc765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/35000000/34830000/34822200/34822185/52f4f498.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/35000000/34830000/34822200/34822185/c7daa4fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Lions Den Pt. II by Innsbrook Vacations! [](https://www.expedia.ca/Wright-City-Hotels-The-Lions-Den-Pt-II-By-Innsbrook-Vacations.h34822185.Hotel-Information) Innsbrook 8.8/10 Excellent (10 reviews) "Comfortable condo right near the lake. We had a great time!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alison T. CA $185 CA $509 total includes taxes & fees Mar 27 - Mar 28 [](https://www.expedia.ca/Wright-City-Hotels-The-Lions-Den-Pt-II-By-Innsbrook-Vacations.h34822185.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/987de7bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/21b63566.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV, fireplace](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/d5079940.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/35000000/34820000/34819200/34819110/51dd894a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Harris Overlook by Innsbrook Vacations! [](https://www.expedia.ca/Wright-City-Hotels-The-Harris-Overlook-By-Innsbrook-Vacations.h34819110.Hotel-Information) Innsbrook 9.4/10 Exceptional (21 reviews) "Great location and property within close distance of all Innsbrook has to offer. Would stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina U. [](https://www.expedia.ca/Wright-City-Hotels-The-Harris-Overlook-By-Innsbrook-Vacations.h34819110.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/eaf810ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/4d333dda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/d4e26647.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/103000000/102260000/102252500/102252443/95cd9c8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Spacious 4BR Home for Families & Pets [](https://www.expedia.ca/St-Louis-Hotels-4-Bedroom-Wentzville-Home-By-StayLage.h102252443.Hotel-Information) Wentzville 9.8/10 Exceptional (6 reviews) "Amazing for attending the fireworks festivals nearby. Great shops walking distance for coffee and food" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tom K. CA $215 CA $668 total includes taxes & fees Mar 31 - Apr 1 [](https://www.expedia.ca/St-Louis-Hotels-4-Bedroom-Wentzville-Home-By-StayLage.h102252443.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/d26497ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Children's area](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/48c79dfa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/w1354h894x2y0-ad017ad0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/105000000/104480000/104472500/104472401/80bc7b28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Studio Condo on the Water @ Innsbrook [](https://www.expedia.ca/Wright-City-Hotels-Bright-Studio-Condo-On-The-Water.h104472401.Hotel-Information) Wright City 9.8/10 Exceptional (46 reviews) "It was very peaceful and close to all the activities we wanted to do like kayak fish and enjoy dinner looking out at the golf course. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mollie L. CA $92 CA $253 total includes taxes & fees Mar 27 - Mar 28 [](https://www.expedia.ca/Wright-City-Hotels-Bright-Studio-Condo-On-The-Water.h104472401.Hotel-Information) ![5 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/270-eee042bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/a076052e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/42026370.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, hair dryer, soap](https://images.trvl-media.com/lodging/35000000/34110000/34101200/34101145/c90a58e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Large Villa Ste A, 1 Mile to Six Flags & Hidden Valley! [](https://www.expedia.ca/St-Louis-Hotels-Large-Villa-Ste-A.h34101145.Hotel-Information) Eureka 9.2/10 Wonderful (46 reviews) "Perfect for large group near 6 flags" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) sean p. CA $344 CA $581 total includes taxes & fees Apr 6 - Apr 7 [](https://www.expedia.ca/St-Louis-Hotels-Large-Villa-Ste-A.h34101145.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/37000000/36860000/36859200/36859133/2193d9c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/37000000/36860000/36859200/36859133/38348e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/37000000/36860000/36859200/36859133/df1c4705.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/37000000/36860000/36859200/36859133/11ca2682.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hound Haus - Dog Friendly, near Purina Farms and WashMO [](https://www.expedia.ca/Villa-Ridge-Hotels-Hound-Haus-Dog-Friendly.h36859133.Hotel-Information) Villa Ridge 9.8/10 Exceptional (34 reviews) "If you want a tiny house experience while attending a dog show at Purina Farms, Hound Haus is the place. 7-10 min from Purina, quiet clean place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Karen M. CA $292 CA $395 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Villa-Ridge-Hotels-Hound-Haus-Dog-Friendly.h36859133.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/63000000/62610000/62603000/62602956/e2923039.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/63000000/62610000/62603000/62602956/d8907016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/63000000/62610000/62603000/62602956/488c5e45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business centre](https://images.trvl-media.com/lodging/63000000/62610000/62603000/62602956/0ab23e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Featured on USA Today - Hot tub, Fenced Yard [](https://www.expedia.ca/Washington-Hotels-Presidents-Office-Featured-On-USA-Today-Travel.h62602956.Hotel-Information) Marthasville 10/10 Exceptional (27 reviews) "Clean place very comfortable. We had a very relaxing stay and would definitely stay again. Relaxing hot tub. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brian CA $377 CA $459 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Washington-Hotels-Presidents-Office-Featured-On-USA-Today-Travel.h62602956.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/93000000/92960000/92957200/92957117/30fad342.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball](https://images.trvl-media.com/lodging/93000000/92960000/92957200/92957117/988c5508.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 bedrooms, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/93000000/92960000/92957200/92957117/b7520d10.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, foosball](https://images.trvl-media.com/lodging/93000000/92960000/92957200/92957117/78f15515.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lots of Space! Central to St Charles and STL. Newly Remodeled. Large Backyard! [](https://www.expedia.ca/St-Louis-Hotels-Lots-Of-Space-Central-To-St-Charles-And-STL-Newly-Remodeled-Large-Backyard.h92957117.Hotel-Information) Maryland Heights 8.6/10 Excellent (26 reviews) "Amazing experience very clean property. Beautiful home with anything you could need for your stay. Helpful host if anything was needed during the stay I knew I could contact the host." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brandon C. CA $315 CA $768 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/St-Louis-Hotels-Lots-Of-Space-Central-To-St-Charles-And-STL-Newly-Remodeled-Large-Backyard.h92957117.Hotel-Information) ![Living area](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/9a628f50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/w2046h3071x2y0-9d212a09.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/86da7218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/97000000/96670000/96666500/96666416/96865d72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy and Modern Augusta Hideaway Near Wineries and Katy Trail [](https://www.expedia.ca/Augusta-Hotels-Cozy-And-Modern-Augusta-Hideaway-Near-Wineries-And-Katy-Trail.h96666416.Hotel-Information) Augusta 10/10 Exceptional (35 reviews) "Great place to stay in Augusta" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William D. CA $296 CA $518 total includes taxes & fees Apr 6 - Apr 7 [](https://www.expedia.ca/Augusta-Hotels-Cozy-And-Modern-Augusta-Hideaway-Near-Wineries-And-Katy-Trail.h96666416.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/120000000/119650000/119642100/119642059/67dc9652.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/120000000/119650000/119642100/119642059/b867baf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/120000000/119650000/119642100/119642059/213c8b19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119650000/119642100/119642059/9b5c84b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Schoolhouse: Dog-friendly, Large Yard, near Purina, Wheelchair friendly [](https://www.expedia.ca/Washington-Hotels-Schoolhouse-Dog-Friendly.h119642059.Hotel-Information) Washington 10/10 Exceptional (5 reviews) "Nice property with great host" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) charlie f. CA $329 CA $398 total includes taxes & fees Mar 29 - Mar 30 [](https://www.expedia.ca/Washington-Hotels-Schoolhouse-Dog-Friendly.h119642059.Hotel-Information) ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/ff8410c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/f7a9c2d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV, fireplace, computer monitors](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/5be8599f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/89000000/88980000/88972400/88972328/6f923e6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming open 4bd and screen-in porch! Sleeps 10! [](https://www.expedia.ca/St-Louis-Hotels-Charming-Open-4bd-And-Screen-In-Porch-Sleeps-10.h88972328.Hotel-Information) Saint Charles 9.2/10 Wonderful (36 reviews) "Stay here for 3 weeks. Place was just as described. Would recommend. Thank you " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eddy CA $300 CA $743 total includes taxes & fees Mar 30 - Mar 31 [](https://www.expedia.ca/St-Louis-Hotels-Charming-Open-4bd-And-Screen-In-Porch-Sleeps-10.h88972328.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-09&endDate=2026-04-10®ionId=6353634&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true) ## Find vacation rentals that suit your style Cabins [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=CABIN) Aparthotels [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=APART_HOTEL) Cottages [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=COTTAGE) Private vacation homes [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=VACATION_HOME) Apartments [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=APARTMENT) Condos [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=CONDO) Villas [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=VILLA) Chalets [](https://www.expedia.ca/Hotel-Search?destination=Defiance%2C+Missouri%2C+United+States+of+America®ionId=6353634&latLong=38.632504%2C-90.778183&adults=2&startDate=2026-06-24&d1=2026-06-24&endDate=2026-06-27&d2=2026-06-27&lodging=CHALET) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Vacation-Rentals.d6353634.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDefiance-Vacation-Rentals.d6353634.Travel-Guide-VacationRentals) ## Top Defiance Hotel Reviews ![Elimwood Hotel, a Ramada by Wyndham](https://images.trvl-media.com/lodging/1000000/30000/25500/25401/6eb87806_y.jpg) ### Elimwood Hotel, a Ramada by Wyndham 2/10 Terrible "I booked a room at this hotel and when I got there, everything’s booked I had to have the merchant canceled the room and then never received my refund" [](https://expedia.ca/St-Louis-Hotels-Elimwood-Hotel.h25401.Hotel-Information) ![Drury Plaza Hotel St. Louis St. Charles](https://images.trvl-media.com/lodging/19000000/18760000/18754300/18754262/79d56802_y.jpg) ### Drury Plaza Hotel St. Louis St. Charles 10/10 Excellent "Very good place especially for families with kids . Excellent service from staff. Very convenient with all the stores around it . One thing though, one elevator was not working and it was very inconveniencing . Hopefully it was a quick fix . " [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-St-Charles.h18754262.Hotel-Information) ![Sonesta ES Suites St. Louis - Chesterfield](https://images.trvl-media.com/lodging/1000000/10000/500/422/6f160867_y.jpg) ### Sonesta ES Suites St. Louis - Chesterfield 10/10 Excellent "Went to visit family. Good location to visit" [](https://expedia.ca/St-Louis-Hotels-Sonesta-ES-Suites-St-Louis-Chesterfield.h422.Hotel-Information) ![Crowne Plaza St. Louis Airport by IHG](https://images.trvl-media.com/lodging/1000000/10000/3100/3010/90ecdcdc_y.jpg) ### Crowne Plaza St. Louis Airport by IHG 10/10 Excellent "Swimming pool wasn't in service " [](https://expedia.ca/St-Louis-Hotels-Crowne-Plaza-St-Louis-Airport.h3010.Hotel-Information) ![Fairfield Inn & Suites by Marriott St. Louis Chesterfield](https://images.trvl-media.com/lodging/1000000/130000/126800/126794/f06ceba4_y.jpg) ### Fairfield Inn & Suites by Marriott St. Louis Chesterfield 10/10 Excellent "The outside was a mess because of construction going on. But the inside was nice. " [](https://expedia.ca/St-Louis-Hotels-SpringHill-Suites-By-Marriott-St-Louis-Chesterfield.h126794.Hotel-Information) ![Drury Inn & Suites Southwest St. Louis](https://images.trvl-media.com/lodging/1000000/980000/976200/976140/416a6a90_y.jpg) ### Drury Inn & Suites Southwest St. Louis 10/10 Excellent "This hotel was an unexpected surprise! We arrived about 5:00, just in time for dinner! The assortment of food was amazing! Next morning, breakfast was served , too! The rooms were very nice and comfortable… we will return!" [](https://expedia.ca/St-Louis-Hotels-Drury-Inn-Suites-Southwest-St-Louis.h976140.Hotel-Information) ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db_y.jpg) ### Ameristar Casino Resort and Spa 10/10 Excellent "great place to stay and play" [](https://expedia.ca/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![Drury Plaza Hotel St. Louis Chesterfield](https://images.trvl-media.com/lodging/2000000/1350000/1346800/1346760/69d580ec_y.jpg) ### Drury Plaza Hotel St. Louis Chesterfield 10/10 Excellent "Fantastic stay." [](https://expedia.ca/St-Louis-Hotels-Drury-Plaza-Hotel-St-Louis-Chesterfield.h1346760.Hotel-Information) ![Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West](https://images.trvl-media.com/lodging/2000000/1660000/1659000/1658956/a165f739_y.jpg) ### Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West 2/10 Terrible "Cards constantly messing up One time had to wait 30 mins for front desk to come and she was in the room right behind the desk even after knocking a few times " [](https://expedia.ca/St-Louis-Hotels-Larkspur-Landing-Extended-Stay-Suites-St-Louis-Riverport-Airport-West.h1658956.Hotel-Information) ## Find out more about Defiance You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded. As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Defiance. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do. ## Explore a world of travel with Expedia - Trending destinations on Expedia.ca - All accommodation types in Defiance ### Trending destinations on Expedia.ca - [Canmore Vacation Rentals ](https://www.expedia.ca/Canmore-Vacation-Rentals.d10131.Travel-Guide-VacationRentals) - [Maui Vacation Rentals ](https://www.expedia.ca/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals) - [Kelowna Vacation Rentals ](https://www.expedia.ca/Kelowna-Vacation-Rentals.d3997.Travel-Guide-VacationRentals) - [Whistler Vacation Rentals ](https://www.expedia.ca/Whistler-Vacation-Rentals.d4115.Travel-Guide-VacationRentals) - [Florida Vacation Rentals ](https://www.expedia.ca/Destinations-In-Florida.d211.Vacation-Rental-Destinations) - [Victoria Vacation Rentals ](https://www.expedia.ca/Victoria-Vacation-Rentals.d4138.Travel-Guide-VacationRentals) - [Vancouver Vacation Rentals ](https://www.expedia.ca/Vancouver-Vacation-Rentals.d178315.Travel-Guide-VacationRentals) - [Palm Springs Vacation Rentals ](https://www.expedia.ca/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals) - [Tofino Vacation Rentals ](https://www.expedia.ca/Tofino-Vacation-Rentals.d6094955.Travel-Guide-VacationRentals) - [Calgary Vacation Rentals ](https://www.expedia.ca/Calgary-Vacation-Rentals.d178245.Travel-Guide-VacationRentals) - [Costa Rica Vacation Rentals ](https://www.expedia.ca/Destinations-In-Costa-Rica.d42.Vacation-Rental-Destinations) - [Vancouver Island Vacation Rentals ](https://www.expedia.ca/Vancouver-Island-Vacation-Rentals.d6058387.Travel-Guide-VacationRentals) - [Puerto Vallarta Vacation Rentals ](https://www.expedia.ca/Puerto-Vallarta-Vacation-Rentals.d180016.Travel-Guide-VacationRentals) - [Hawaii Vacation Rentals ](https://www.expedia.ca/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations) - [Toronto Vacation Rentals ](https://www.expedia.ca/Toronto-Vacation-Rentals.d178314.Travel-Guide-VacationRentals) - [Banff Vacation Rentals ](https://www.expedia.ca/Banff-Vacation-Rentals.d10550.Travel-Guide-VacationRentals) - [Penticton Vacation Rentals ](https://www.expedia.ca/Penticton-Vacation-Rentals.d4135.Travel-Guide-VacationRentals) - [Osoyoos Vacation Rentals ](https://www.expedia.ca/Osoyoos-Vacation-Rentals.d181782.Travel-Guide-VacationRentals) - [Mont Tremblant Vacation Rentals ](https://www.expedia.ca/Mont-Tremblant-Vacation-Rentals.d55374.Travel-Guide-VacationRentals) - [Big White Ski Resort Vacation Rentals ](https://www.expedia.ca/Big-White-Ski-Resort-Vacation-Rentals.d6058319.Travel-Guide-VacationRentals) - [Ontario Vacation Rentals ](https://www.expedia.ca/Destinations-In-Ontario.d11178.Vacation-Rental-Destinations) - [British Columbia Vacation Rentals ](https://www.expedia.ca/Destinations-In-British-Columbia.d11117.Vacation-Rental-Destinations) - [Prince Edward Island Vacation Rentals ](https://www.expedia.ca/Destinations-In-Prince-Edward-Island.d6058122.Vacation-Rental-Destinations) - [Québec Vacation Rentals ](https://www.expedia.ca/Quebec-Vacation-Rentals.d180017.Travel-Guide-VacationRentals) - [Vacation Homes in Defiance ](https://expedia.ca/Defiance-Private-Vacation-Homes.d6353634-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Chalets in Defiance ](https://expedia.ca/Defiance-Chalets.d6353634-aaChalets.Travel-Guide-Accommodation) - [Apartments in Defiance ](https://expedia.ca/Defiance-Apartments.d6353634-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Defiance ](https://expedia.ca/Defiance-Condos.d6353634-aaCondos.Travel-Guide-Accommodation) - [Cottages in Defiance ](https://expedia.ca/Defiance-Cottages.d6353634-aaCottages.Travel-Guide-Accommodation) - [Cabin Rentals in Defiance ](https://expedia.ca/Defiance-Cabins.d6353634-aaCabins.Travel-Guide-Accommodation) - [B&B in Defiance ](https://expedia.ca/Defiance-Bed-And-Breakfast.d6353634-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Motels in Defiance ](https://expedia.ca/Defiance-Motels.d6353634-aaMotels.Travel-Guide-Accommodation) - [Aparthotels in Defiance ](https://expedia.ca/Defiance-Apart-Hotels.d6353634-aaApartHotels.Travel-Guide-Accommodation) - [Villas in Defiance ](https://expedia.ca/Defiance-Villas.d6353634-aaVillas.Travel-Guide-Accommodation) - [RV Parks in Defiance ](https://expedia.ca/Defiance-RV-Parks.d6353634-aaRVParks.Travel-Guide-Accommodation) - [Lodges in Defiance ](https://expedia.ca/Defiance-Lodges.d6353634-aaLodges.Travel-Guide-Accommodation) - [Inns in Defiance ](https://expedia.ca/Defiance-Inns.d6353634-aaInns.Travel-Guide-Accommodation) - [Hostels in Defiance ](https://expedia.ca/Defiance-Hostels.d6353634-aaHostels.Travel-Guide-Accommodation) - [Resorts in Defiance ](https://expedia.ca/Defiance-Resort-Hotels.d6353634-aaResortHotels.Travel-Guide-Accommodation) - [Guest Houses in Defiance ](https://expedia.ca/Defiance-Guest-Houses.d6353634-aaGuestHouses.Travel-Guide-Accommodation) ## Frequently asked questions ### Can I find vacation rentals in Defiance? ### What are some of the best vacation home rentals that Defiance has to offer? ### How many vacation rentals will I find in Defiance? ### What’s there to see and do in Defiance? ### What’s a vacation rental in Defiance like? ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app